Idiopathic Inflammatory Myopathy with Diffuse Alveolar Damage
Identifieur interne : 001F34 ( Istex/Corpus ); précédent : 001F33; suivant : 001F35Idiopathic Inflammatory Myopathy with Diffuse Alveolar Damage
Auteurs : C.-S. Lee ; T.-L. Chen ; C.-Y. Tzen ; F.-J. Lin ; M.-J. Peng ; C.-L. Wu ; P.-J. ChenSource :
- Clinical Rheumatology [ 0770-3198 ] ; 2002-09-01.
English descriptors
Abstract
Abstract:: Interstitial lung disease (ILD) in patients with myositis is defined by the presence of interstitial changes on radiographic examination. The reported prevalence of ILD varies from 0% to nearly 50%. However, only rarely has the pathological pattern of diffuse alveolar damage (DAD) associated with idiopathic inflammatory myopathy (IIM) been reported. We report five patients with IIM (one with dermatomyositis, one with polymyositis, and three with amyopathic dermatomyositis) and respiratory failure. Four underwent open lung biopsy with pathological proof of diffuse alveolar damage (DAD). Despite intensive immunosuppressive therapy, all of them died. In addition to the case reports, we discuss DAD in patients with IIM.
Url:
DOI: 10.1007/s100670200104
Links to Exploration step
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<front><div type="abstract" xml:lang="en">Abstract:: Interstitial lung disease (ILD) in patients with myositis is defined by the presence of interstitial changes on radiographic examination. The reported prevalence of ILD varies from 0% to nearly 50%. However, only rarely has the pathological pattern of diffuse alveolar damage (DAD) associated with idiopathic inflammatory myopathy (IIM) been reported. We report five patients with IIM (one with dermatomyositis, one with polymyositis, and three with amyopathic dermatomyositis) and respiratory failure. Four underwent open lung biopsy with pathological proof of diffuse alveolar damage (DAD). Despite intensive immunosuppressive therapy, all of them died. In addition to the case reports, we discuss DAD in patients with IIM.</div>
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<Para> Interstitial lung disease (ILD) in patients with myositis is defined by the presence of interstitial changes on radiographic examination. The reported prevalence of ILD varies from 0% to nearly 50%. However, only rarely has the pathological pattern of diffuse alveolar damage (DAD) associated with idiopathic inflammatory myopathy (IIM) been reported. We report five patients with IIM (one with dermatomyositis, one with polymyositis, and three with amyopathic dermatomyositis) and respiratory failure. Four underwent open lung biopsy with pathological proof of diffuse alveolar damage (DAD). Despite intensive immunosuppressive therapy, all of them died. In addition to the case reports, we discuss DAD in patients with IIM.</Para>
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<place><placeTerm type="text">London</placeTerm>
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<dateIssued encoding="w3cdtf">2002-09-01</dateIssued>
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<abstract lang="en">Abstract:: Interstitial lung disease (ILD) in patients with myositis is defined by the presence of interstitial changes on radiographic examination. The reported prevalence of ILD varies from 0% to nearly 50%. However, only rarely has the pathological pattern of diffuse alveolar damage (DAD) associated with idiopathic inflammatory myopathy (IIM) been reported. We report five patients with IIM (one with dermatomyositis, one with polymyositis, and three with amyopathic dermatomyositis) and respiratory failure. Four underwent open lung biopsy with pathological proof of diffuse alveolar damage (DAD). Despite intensive immunosuppressive therapy, all of them died. In addition to the case reports, we discuss DAD in patients with IIM.</abstract>
<note>Case Report</note>
<subject lang="en"><topic>Key words:Diffuse alveolar damage – Idiopathic inflammatory myopathy – Respiratory failure</topic>
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<relatedItem type="host"><titleInfo><title>Clinical Rheumatology</title>
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<titleInfo type="abbreviated"><title>Clin Rheumatol</title>
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<originInfo><publisher>Springer</publisher>
<dateIssued encoding="w3cdtf">2002-09-01</dateIssued>
<copyrightDate encoding="w3cdtf">2002</copyrightDate>
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<subject><genre>Journal-Subject-Group</genre>
<topic authority="SpringerSubjectCodes" authorityURI="SCH">Medicine & Public Health</topic>
<topic authority="SpringerSubjectCodes" authorityURI="SCH57009">Rheumatology</topic>
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<identifier type="ISSN">0770-3198</identifier>
<identifier type="eISSN">1434-9949</identifier>
<identifier type="JournalID">10067</identifier>
<identifier type="VolumeIssueCount">6</identifier>
<part><date>2002</date>
<detail type="volume"><number>21</number>
<caption>vol.</caption>
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<detail type="issue"><number>5</number>
<caption>no.</caption>
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<extent unit="pages"><start>391</start>
<end>396</end>
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<identifier type="DOI">10.1007/s100670200104</identifier>
<identifier type="ArticleID">210500391</identifier>
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<accessCondition type="use and reproduction" contentType="copyright">Clinical Rheumatology, 2002</accessCondition>
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