Severe spirometric defects in systemic lupus erythematosus A possible role for bronchoalveolar lavage and gallium scanning
Identifieur interne : 001F27 ( Istex/Corpus ); précédent : 001F26; suivant : 001F28Severe spirometric defects in systemic lupus erythematosus A possible role for bronchoalveolar lavage and gallium scanning
Auteurs : R. Y. LinSource :
- Clinical Rheumatology [ 0770-3198 ] ; 1987-06-01.
English descriptors
- KwdEn :
- Teeft :
- Alveolar macrophages, Alveolitis, Bronchoalveolar, Bronchoalveolar lavage, Chronic inflammation, Corticosteroid therapy, Dlco, Erythematosus, Gallium scan, Gallium scanning, Gallium scans, Inflammation, Interstitial, Interstitial disease, Interstitial lung disease, Interstitial markings, Interstitial pneumonitis, Laboratory examination, Lavage, Lung tissue, Lupus, Lupus pneumonitis, Normal urinalysis, Open lung biopsy, Partial relief, Physical examination, Pleuritic chest pain, Pneumonitis, Polymorphonuclear leukocytes, Pulmonary disease, Pulmonary fibrosis, Pulmonary function studies, Pulmonary function tests, Pulmonary function values, Pulmonary functions, Pulmonary inflammation, Serological values, Severe spirometric defects, Steroid therapy, Suppressor ratio, Symptomatic improvement, Systemic, Systemic lupus erythematosus, Tongue ulcers, Treatment efficacy, University hospital.
Abstract
Summary: Two patients with systemic lupus erythematosus (SLE) developed progressive chronic pulmonary disease. Pulmonary bronchoalveolar lavage (BAL) and Gallium-67 scanning were performed and were consistent with alveolitis. In one patient, an open lung biopsy was performed and showed the presence of several immunoreactants as well as interstitial pneumonitis. Although mild pulmonary function abnormalities are common in SLE, some patients such as the two described in this report develop progressive and incapacitating pulmonary impairment. The need for developing standardized indices of pulmonary inflammation such as BAL and gallium scanning for the purposes of diagnosis, prognostication, and monitoring treatment responses in systemic lupus erythematosus is stressed.
Url:
DOI: 10.1007/BF02201037
Links to Exploration step
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<Para>Two patients with systemic lupus erythematosus (SLE) developed progressive chronic pulmonary disease. Pulmonary bronchoalveolar lavage (BAL) and Gallium-67 scanning were performed and were consistent with alveolitis. In one patient, an open lung biopsy was performed and showed the presence of several immunoreactants as well as interstitial pneumonitis. Although mild pulmonary function abnormalities are common in SLE, some patients such as the two described in this report develop progressive and incapacitating pulmonary impairment. The need for developing standardized indices of pulmonary inflammation such as BAL and gallium scanning for the purposes of diagnosis, prognostication, and monitoring treatment responses in systemic lupus erythematosus is stressed.</Para>
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<originInfo><publisher>Springer-Verlag</publisher>
<place><placeTerm type="text">London</placeTerm>
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<dateCreated encoding="w3cdtf">1986-07-15</dateCreated>
<dateIssued encoding="w3cdtf">1987-06-01</dateIssued>
<copyrightDate encoding="w3cdtf">1987</copyrightDate>
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<abstract lang="en">Summary: Two patients with systemic lupus erythematosus (SLE) developed progressive chronic pulmonary disease. Pulmonary bronchoalveolar lavage (BAL) and Gallium-67 scanning were performed and were consistent with alveolitis. In one patient, an open lung biopsy was performed and showed the presence of several immunoreactants as well as interstitial pneumonitis. Although mild pulmonary function abnormalities are common in SLE, some patients such as the two described in this report develop progressive and incapacitating pulmonary impairment. The need for developing standardized indices of pulmonary inflammation such as BAL and gallium scanning for the purposes of diagnosis, prognostication, and monitoring treatment responses in systemic lupus erythematosus is stressed.</abstract>
<note>Case Report</note>
<subject lang="en"><genre>Key words</genre>
<topic>Bronchoalveolar Lavage</topic>
<topic>Gallium Scan</topic>
<topic>Systemic Lupus Erythematosus</topic>
<topic>Pulmonary Function Tests</topic>
<topic>Alveolitis</topic>
</subject>
<relatedItem type="host"><titleInfo><title>Clinical Rheumatology</title>
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<titleInfo type="abbreviated"><title>Clin Rheumatol</title>
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<genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre>
<originInfo><publisher>Springer</publisher>
<dateIssued encoding="w3cdtf">1987-06-01</dateIssued>
<copyrightDate encoding="w3cdtf">1987</copyrightDate>
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<subject><genre>Medicine & Public Health</genre>
<topic>Rheumatology</topic>
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<identifier type="ISSN">0770-3198</identifier>
<identifier type="eISSN">1434-9949</identifier>
<identifier type="JournalID">10067</identifier>
<identifier type="IssueArticleCount">35</identifier>
<identifier type="VolumeIssueCount">4</identifier>
<part><date>1987</date>
<detail type="volume"><number>6</number>
<caption>vol.</caption>
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<detail type="issue"><number>2</number>
<caption>no.</caption>
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<extent unit="pages"><start>276</start>
<end>281</end>
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<recordInfo><recordOrigin>Acta Medica Belgica, 1987</recordOrigin>
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<identifier type="DOI">10.1007/BF02201037</identifier>
<identifier type="ArticleID">BF02201037</identifier>
<identifier type="ArticleID">Art21</identifier>
<accessCondition type="use and reproduction" contentType="copyright">Acta Medica Belgica, 1987</accessCondition>
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