Improved rheumatoid digital vasculitis in a patient treated with TNFα agent blocking (infliximab)
Identifieur interne : 001E61 ( Istex/Corpus ); précédent : 001E60; suivant : 001E62Improved rheumatoid digital vasculitis in a patient treated with TNFα agent blocking (infliximab)
Auteurs : Maurizio Benucci ; Francesca Li Gobbi ; Gianantonio Saviola ; Mariangela ManfrediSource :
- Rheumatology International [ 0172-8172 ] ; 2008-10-01.
English descriptors
Abstract
Abstract: Rheumatoid vasculitis (RV) is an uncommon but potentially catastrophic complication of rheumatoid arthritis (RA). There are few current extensive studies and no consensus regarding the clinical, laboratory, histologic features and management or prognosis of RV. We report a case of RV in a 74-year old woman with a long (14 years) history of RA, who developed vasculitis of distal arteries with gangrene of digits of upper and lower extremities. After the failure of various immunosuppressive drugs (cyclophosphamide, methotrexate), the patient was treated with anti-TNFalpha infliximab. Digital gangrene healed within four months from the start of anti-TNFalpha treatment.
Url:
DOI: 10.1007/s00296-008-0592-x
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Giovanni di Dio, ASL 10, Florence, Italy</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Rheumatology International</title><title level="j" type="sub">Clinical and Experimental Investigations</title><title level="j" type="abbrev">Rheumatol Int</title><idno type="ISSN">0172-8172</idno><idno type="eISSN">1437-160X</idno><imprint><publisher>Springer-Verlag</publisher><pubPlace>Berlin/Heidelberg</pubPlace><date type="published" when="2008-10-01">2008-10-01</date><biblScope unit="volume">28</biblScope><biblScope unit="issue">12</biblScope><biblScope unit="page" from="1253">1253</biblScope><biblScope unit="page" to="1255">1255</biblScope></imprint><idno type="ISSN">0172-8172</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0172-8172</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Rheumatoid vasculitis</term><term>TNFα blocking agents</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: Rheumatoid vasculitis (RV) is an uncommon but potentially catastrophic complication of rheumatoid arthritis (RA). There are few current extensive studies and no consensus regarding the clinical, laboratory, histologic features and management or prognosis of RV. We report a case of RV in a 74-year old woman with a long (14 years) history of RA, who developed vasculitis of distal arteries with gangrene of digits of upper and lower extremities. After the failure of various immunosuppressive drugs (cyclophosphamide, methotrexate), the patient was treated with anti-TNFalpha infliximab. Digital gangrene healed within four months from the start of anti-TNFalpha treatment.</div></front></TEI><istex><corpusName>springer-journals</corpusName><author><json:item><name>Maurizio Benucci</name><affiliations><json:string>Rheumatology Unit, Nuovo Ospedale S. 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Grant="OpenAccess"></AbstractGrant><BodyPDFGrant Grant="Restricted"></BodyPDFGrant><BodyHTMLGrant Grant="Restricted"></BodyHTMLGrant><BibliographyGrant Grant="Restricted"></BibliographyGrant><ESMGrant Grant="Restricted"></ESMGrant></ArticleGrants></ArticleInfo><ArticleHeader><AuthorGroup><Author AffiliationIDS="Aff1" CorrespondingAffiliationID="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Maurizio</GivenName><FamilyName>Benucci</FamilyName></AuthorName><Contact><Phone>+39-055-7192331</Phone><Fax>+39-055-7192260</Fax><Email>maubenucci@tiscali.it</Email><Email>maurizio.benucci@asf.toscana.it</Email></Contact></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Francesca</GivenName><FamilyName>Li Gobbi</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff2"><AuthorName DisplayOrder="Western"><GivenName>Gianantonio</GivenName><FamilyName>Saviola</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff3"><AuthorName DisplayOrder="Western"><GivenName>Mariangela</GivenName><FamilyName>Manfredi</FamilyName></AuthorName></Author><Affiliation ID="Aff1"><OrgDivision>Rheumatology Unit</OrgDivision><OrgName>Nuovo Ospedale S. Giovanni di Dio</OrgName><OrgAddress><Street>ASL 10 Florence via di Torregalli 3</Street><City>Florence</City><Country Code="IT">Italy</Country></OrgAddress></Affiliation><Affiliation ID="Aff2"><OrgDivision>Rheumatology and Rehabilitation Unit</OrgDivision><OrgName>S. Maugeri Foundation IRCCS</OrgName><OrgAddress><City>Mantua</City><Country Code="IT">Italy</Country></OrgAddress></Affiliation><Affiliation ID="Aff3"><OrgDivision>Immunology and Allergology Laboratory Unit</OrgDivision><OrgName>Nuovo Ospedale S. Giovanni di Dio</OrgName><OrgAddress><Street>ASL 10</Street><City>Florence</City><Country Code="IT">Italy</Country></OrgAddress></Affiliation></AuthorGroup><Abstract ID="Abs1" Language="En"><Heading>Abstract</Heading><Para TextBreak="No">Rheumatoid vasculitis (RV) is an uncommon but potentially catastrophic complication of rheumatoid arthritis (RA). There are few current extensive studies and no consensus regarding the clinical, laboratory, histologic features and management or prognosis of RV. We report a case of RV in a 74-year old woman with a long (14 years) history of RA, who developed vasculitis of distal arteries with gangrene of digits of upper and lower extremities. After the failure of various immunosuppressive drugs (cyclophosphamide, methotrexate), the patient was treated with anti-TNFalpha infliximab. Digital gangrene healed within four months from the start of anti-TNFalpha treatment.</Para></Abstract><KeywordGroup Language="En"><Heading>Keywords</Heading><Keyword>Rheumatoid vasculitis</Keyword><Keyword>TNFα blocking agents</Keyword></KeywordGroup></ArticleHeader><NoBody></NoBody></Article></Issue></Volume></Journal></Publisher></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Improved rheumatoid digital vasculitis in a patient treated with TNFα agent blocking (infliximab)</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Improved rheumatoid digital vasculitis in a patient treated with TNFα agent blocking (infliximab)</title></titleInfo><name type="personal" displayLabel="corresp"><namePart type="given">Maurizio</namePart><namePart type="family">Benucci</namePart><affiliation>Rheumatology Unit, Nuovo Ospedale S. Giovanni di Dio, ASL 10 Florence via di Torregalli 3, Florence, Italy</affiliation><affiliation>E-mail: maubenucci@tiscali.it</affiliation><affiliation>E-mail: maurizio.benucci@asf.toscana.it</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Francesca</namePart><namePart type="family">Li Gobbi</namePart><affiliation>Rheumatology Unit, Nuovo Ospedale S. Giovanni di Dio, ASL 10 Florence via di Torregalli 3, Florence, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Gianantonio</namePart><namePart type="family">Saviola</namePart><affiliation>Rheumatology and Rehabilitation Unit, S. Maugeri Foundation IRCCS, Mantua, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Mariangela</namePart><namePart type="family">Manfredi</namePart><affiliation>Immunology and Allergology Laboratory Unit, Nuovo Ospedale S. Giovanni di Dio, ASL 10, Florence, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="OriginalPaper" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-1JC4F85T-7">research-article</genre><originInfo><publisher>Springer-Verlag</publisher><place><placeTerm type="text">Berlin/Heidelberg</placeTerm></place><dateCreated encoding="w3cdtf">2008-01-08</dateCreated><dateIssued encoding="w3cdtf">2008-10-01</dateIssued><copyrightDate encoding="w3cdtf">2008</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><abstract lang="en">Abstract: Rheumatoid vasculitis (RV) is an uncommon but potentially catastrophic complication of rheumatoid arthritis (RA). There are few current extensive studies and no consensus regarding the clinical, laboratory, histologic features and management or prognosis of RV. We report a case of RV in a 74-year old woman with a long (14 years) history of RA, who developed vasculitis of distal arteries with gangrene of digits of upper and lower extremities. After the failure of various immunosuppressive drugs (cyclophosphamide, methotrexate), the patient was treated with anti-TNFalpha infliximab. 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|type= RBID
|clé= ISTEX:B9FCDE3366A07A35ECFB96948364BD27CE4BD3ED
|texte= Improved rheumatoid digital vasculitis in a patient treated with TNFα agent blocking (infliximab)
}}
| This area was generated with Dilib version V0.6.33. |  |