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A search for natural bioactive compounds in Bolivia through a multidisciplinary approach

Identifieur interne : 001C46 ( Istex/Corpus ); précédent : 001C45; suivant : 001C47

A search for natural bioactive compounds in Bolivia through a multidisciplinary approach

Auteurs : V. Mu Oz ; M. Sauvain ; G. Bourdy ; S. Arrázola ; J. Callapa ; G. Ruiz ; J. Choque ; E. Deharo

Source :

RBID : ISTEX:87AA0C79768600D53C4113C13AAFE3F57CDCEB41

English descriptors

Abstract

Abstract: A total of 40 plant extracts traditionally used by the Alteños Indians, a native community living between the Andean block and the tropical valleys of Bolivia, were screened for antimalarial activity in vitro on Plasmodium falciparum chloroquine resistant (Indo) strain, and in vivo on rodent malaria Plasmodium vinckei petteri. Eleven extracts displayed good or moderate activity in vivo, and ten extracts good or very good antimalarial activity in vitro. Results of the screening are discussed here, in relation with the traditional use of plants.

Url:
DOI: 10.1016/S0378-8741(99)00191-9

Links to Exploration step

ISTEX:87AA0C79768600D53C4113C13AAFE3F57CDCEB41

Le document en format XML

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<div type="abstract" xml:lang="en">Abstract: A total of 40 plant extracts traditionally used by the Alteños Indians, a native community living between the Andean block and the tropical valleys of Bolivia, were screened for antimalarial activity in vitro on Plasmodium falciparum chloroquine resistant (Indo) strain, and in vivo on rodent malaria Plasmodium vinckei petteri. Eleven extracts displayed good or moderate activity in vivo, and ten extracts good or very good antimalarial activity in vitro. Results of the screening are discussed here, in relation with the traditional use of plants.</div>
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