On the medicinal chemistry of ferrocene
Identifieur interne : 000F25 ( Istex/Corpus ); précédent : 000F24; suivant : 000F26On the medicinal chemistry of ferrocene
Auteurs : Mohammad F. R. Fouda ; Mokhles M. Abd-Elzaher ; Rafeek A. Abdelsamaia ; Ammar A. LabibSource :
- Applied Organometallic Chemistry [ 0268-2605 ] ; 2007-08.
English descriptors
- Teeft :
- Anticancer, Anticancer agents, Antimalarial, Antiproliferative, Antiproliferative effect, Antitumor, Appl, Bioorganometallic, Bioorganometallic chemistry, Biot, Breast cancer cells, Brocard, Cell line, Cell lines, Chem, Copyright, Cytotoxic, Cytotoxic effect, Derivative, Dyson, Electrochemical, Falciparum, Ferrocene, Ferrocene derivatives, Ferrocene moiety, Ferrocenyl, Ferrocenyl compounds, Ferrocenyl derivatives, Ferrocenyl moiety, Ferrocifens, Fouda, Hybridization, Important role, Inorg, Jaouen, John wiley sons, Maciejewski, Medicinal, Medicinal chemistry, Moiety, Neuse, Organomet, Organometal, Para, Plasmodium falciparum, Polym, Receptor, Redox, Redox properties, Tamoxifen, Topoisomerase, Vessieres, Weekly epidemiol.
Abstract
Organometallic chemistry and biochemistry have been merged in the last two decades into a new field: bioorganometallic chemistry. This new research area was devoted to the synthesis of new organometallic compounds and their biological and medical effects against some types of diseases, such as cancer and malaria. For several years, the use of ferrocene in bioorganometallic chemistry has been growing rapidly, and several promising applications have been developed since ferrocene is a stable, nontoxic compound and has good redox properties. This review will focus on ferrocenyl compounds which have been biologically evaluated against certain diseases. This area has attracted many researchers due to the promising results of some ferrocene compounds in the medicinal applications. Copyright © 2007 John Wiley & Sons, Ltd.
The use of ferrocene in bioorganometal‐lic chemistry has been growing rapidly, and several promising applications have been developed since ferrocene is a stable compound, nontoxic and has good redox properties. This review will focus on ferrocenyl compounds which have been biologically evaluated against certain diseases. This area has attracted many researchers due to the promising results of some ferrocene compounds in the medicinal applications.
Url:
DOI: 10.1002/aoc.1202
Links to Exploration step
ISTEX:BB8F889A306378A472CEC2729866C81C1B141542Le document en format XML
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Chem.</title></titleGroup></publicationMeta><publicationMeta level="part" position="80"><doi origin="wiley" registered="yes">10.1002/aoc.v21:8</doi><numberingGroup><numbering type="journalVolume" number="21">21</numbering><numbering type="journalIssue">8</numbering></numberingGroup><coverDate startDate="2007-08">August 2007</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="2" status="forIssue"><doi origin="wiley" registered="yes">10.1002/aoc.1202</doi><idGroup><id type="unit" value="AOC1202"></id></idGroup><countGroup><count type="pageTotal" number="13"></count></countGroup><titleGroup><title type="articleCategory">Bioorganometallic Chemistry</title><title type="tocHeading1">Bioorganometallic Chemistry</title></titleGroup><copyright ownership="publisher">Copyright © 2007 John Wiley & Sons, Ltd.</copyright><eventGroup><event type="manuscriptReceived" date="2006-11-01"></event><event type="manuscriptRevised" date="2006-12-06"></event><event type="manuscriptAccepted" date="2006-12-26"></event><event type="publishedOnlineEarlyUnpaginated" date="2007-04-11"></event><event type="firstOnline" date="2007-04-11"></event><event type="publishedOnlineFinalForm" date="2007-06-28"></event><event type="xmlConverted" agent="Converter:JWSART34_TO_WML3G version:2.3.2 mode:FullText source:HeaderRef result:HeaderRef" date="2010-03-09"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-01-04"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-14"></event></eventGroup><numberingGroup><numbering type="pageFirst">613</numbering><numbering type="pageLast">625</numbering></numberingGroup><correspondenceTo>Inorganic Chemistry Department, National Research Centre, PO 12622 Dokki, Cairo, Egypt.</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:AOC.AOC1202.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="22"></count><count type="tableTotal" number="0"></count><count type="referenceTotal" number="118"></count></countGroup><titleGroup><title type="main" xml:lang="en">On the medicinal chemistry of ferrocene</title><title type="short" xml:lang="en">On the medicinal chemistry of ferrocene</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Mohammad F. R.</givenNames><familyName>Fouda</familyName></personName></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af1" corresponding="yes"><personName><givenNames>Mokhles M.</givenNames><familyName>Abd‐Elzaher</familyName></personName><contactDetails><email>mokhlesm20@yahoo.com</email></contactDetails></creator><creator xml:id="au3" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Rafeek A.</givenNames><familyName>Abdelsamaia</familyName></personName></creator><creator xml:id="au4" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Ammar A.</givenNames><familyName>Labib</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="EG" type="organization"><unparsedAffiliation>Inorganic Chemistry Department, National Research Centre, PO 12622 Dokki, Cairo, Egypt</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">bioorganometallic</keyword><keyword xml:id="kwd2">ferrocene</keyword><keyword xml:id="kwd3">anticancer</keyword><keyword xml:id="kwd4">antimalarial</keyword><keyword xml:id="kwd5">HIV</keyword><keyword xml:id="kwd6">DNA detection</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>Organometallic chemistry and biochemistry have been merged in the last two decades into a new field: bioorganometallic chemistry. This new research area was devoted to the synthesis of new organometallic compounds and their biological and medical effects against some types of diseases, such as cancer and malaria. For several years, the use of ferrocene in bioorganometallic chemistry has been growing rapidly, and several promising applications have been developed since ferrocene is a stable, nontoxic compound and has good redox properties. This review will focus on ferrocenyl compounds which have been biologically evaluated against certain diseases. This area has attracted many researchers due to the promising results of some ferrocene compounds in the medicinal applications. Copyright © 2007 John Wiley & Sons, Ltd.</p></abstract><abstract type="graphical" xml:lang="en"><p>The use of ferrocene in bioorganometal‐lic chemistry has been growing rapidly, and several promising applications have been developed since ferrocene is a stable compound, nontoxic and has good redox properties. This review will focus on ferrocenyl compounds which have been biologically evaluated against certain diseases. This area has attracted many researchers due to the promising results of some ferrocene compounds in the medicinal applications. <blockFixed type="graphic"><mediaResourceGroup><mediaResource alt="image" eRights="yes" copyright="John Wiley & Sons, Ltd." href="urn:x-wiley:02682605:media:AOC1202:gra001"></mediaResource><mediaResource alt="thumbnail image" rendition="webLoRes" mimeType="image/gif" href=""></mediaResource><mediaResource alt="original image" rendition="webOriginal" mimeType="image/gif" href=""></mediaResource><mediaResource alt="magnified image" rendition="webHiRes" mimeType="image/gif" href=""></mediaResource></mediaResourceGroup></blockFixed></p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>On the medicinal chemistry of ferrocene</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>On the medicinal chemistry of ferrocene</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>On the medicinal chemistry of ferrocene</title></titleInfo><name type="personal"><namePart type="given">Mohammad F. R.</namePart><namePart type="family">Fouda</namePart><affiliation>Inorganic Chemistry Department, National Research Centre, PO 12622 Dokki, Cairo, Egypt</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Mokhles M.</namePart><namePart type="family">Abd‐Elzaher</namePart><affiliation>Inorganic Chemistry Department, National Research Centre, PO 12622 Dokki, Cairo, Egypt</affiliation><affiliation>E-mail: mokhlesm20@yahoo.com</affiliation><affiliation>Correspondence address: Inorganic Chemistry Department, National Research Centre, PO 12622 Dokki, Cairo, Egypt.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Rafeek A.</namePart><namePart type="family">Abdelsamaia</namePart><affiliation>Inorganic Chemistry Department, National Research Centre, PO 12622 Dokki, Cairo, Egypt</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Ammar A.</namePart><namePart type="family">Labib</namePart><affiliation>Inorganic Chemistry Department, National Research Centre, PO 12622 Dokki, Cairo, Egypt</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</genre><originInfo><publisher>John Wiley & Sons, Ltd.</publisher><place><placeTerm type="text">Chichester, UK</placeTerm></place><dateIssued encoding="w3cdtf">2007-08</dateIssued><dateCaptured encoding="w3cdtf">2006-11-01</dateCaptured><dateValid encoding="w3cdtf">2006-12-26</dateValid><copyrightDate encoding="w3cdtf">2007</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><extent unit="figures">22</extent><extent unit="tables">0</extent><extent unit="references">118</extent></physicalDescription><abstract lang="en">Organometallic chemistry and biochemistry have been merged in the last two decades into a new field: bioorganometallic chemistry. This new research area was devoted to the synthesis of new organometallic compounds and their biological and medical effects against some types of diseases, such as cancer and malaria. For several years, the use of ferrocene in bioorganometallic chemistry has been growing rapidly, and several promising applications have been developed since ferrocene is a stable, nontoxic compound and has good redox properties. This review will focus on ferrocenyl compounds which have been biologically evaluated against certain diseases. This area has attracted many researchers due to the promising results of some ferrocene compounds in the medicinal applications. Copyright © 2007 John Wiley & Sons, Ltd.</abstract><abstract type="graphical" lang="en">The use of ferrocene in bioorganometal‐lic chemistry has been growing rapidly, and several promising applications have been developed since ferrocene is a stable compound, nontoxic and has good redox properties. This review will focus on ferrocenyl compounds which have been biologically evaluated against certain diseases. This area has attracted many researchers due to the promising results of some ferrocene compounds in the medicinal applications.</abstract><subject lang="en"><genre>keywords</genre><topic>bioorganometallic</topic><topic>ferrocene</topic><topic>anticancer</topic><topic>antimalarial</topic><topic>HIV</topic><topic>DNA detection</topic></subject><relatedItem type="host"><titleInfo><title>Applied Organometallic Chemistry</title></titleInfo><titleInfo type="abbreviated"><title>Appl. Organometal. 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