The Role and Therapeutic Potential of Autophagy Modulation in Controlling Virus‐Induced Cell Death
Identifieur interne : 000314 ( Istex/Corpus ); précédent : 000313; suivant : 000315The Role and Therapeutic Potential of Autophagy Modulation in Controlling Virus‐Induced Cell Death
Auteurs : Gordana Tovilovic ; Biljana Ristic ; Marina Milenkovic ; Maja Stanojevic ; Vladimir TrajkovicSource :
- Medicinal Research Reviews [ 0198-6325 ] ; 2014-07.
Abstract
Macroautophagy (hereafter referred to as autophagy) is an evolutionary conserved catabolic process in which the cytoplasmic content is sequestered and degraded by the lysosomal machinery in order to maintain cellular homeostasis or provide energy during metabolic and hypoxic stress. It also represents an important component of the host response against infectious agents, performing surveillance and effector functions involved in detection and clearance of pathogens, including viruses. Moreover, it appears that autophagy plays a major role in determining the fate of both virally infected and uninfected cells by blocking or promoting their death in a virus‐ and cell‐type‐dependent manner. We here review the current knowledge on the complex involvement of autophagy in survival and death of the host cells during viral infection, focusing on the molecular mechanisms underlying viral modulation of autophagic response and its interference with the cell death pathways. We also discuss a possible significance of the autophagy‐dependent modulation of cell death for the outcome and therapy of viral infections, emphasizing the need for a time‐ and cell‐type‐dependent fine‐tuning of the autophagic response in achieving an optimal balance between beneficial and adverse effects.
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DOI: 10.1002/med.21303
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last="Milenkovic">Marina Milenkovic</name><affiliation><mods:affiliation>Institute of Microbiology and Immunology, School of Medicine, University of Belgrade, Dr. Subotica 1, 11000, Belgrade, Serbia</mods:affiliation></affiliation></author><author><name sortKey="Stanojevic, Maja" sort="Stanojevic, Maja" uniqKey="Stanojevic M" first="Maja" last="Stanojevic">Maja Stanojevic</name><affiliation><mods:affiliation>Institute of Microbiology and Immunology, School of Medicine, University of Belgrade, Dr. Subotica 1, 11000, Belgrade, Serbia</mods:affiliation></affiliation></author><author><name sortKey="Trajkovic, Vladimir" sort="Trajkovic, Vladimir" uniqKey="Trajkovic V" first="Vladimir" last="Trajkovic">Vladimir Trajkovic</name><affiliation><mods:affiliation>Institute of Microbiology and Immunology, School of Medicine, University of Belgrade, Dr. Subotica 1, 11000, Belgrade, Serbia</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: 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11000, Belgrade, Serbia</mods:affiliation></affiliation></author><author><name sortKey="Trajkovic, Vladimir" sort="Trajkovic, Vladimir" uniqKey="Trajkovic V" first="Vladimir" last="Trajkovic">Vladimir Trajkovic</name><affiliation><mods:affiliation>Institute of Microbiology and Immunology, School of Medicine, University of Belgrade, Dr. Subotica 1, 11000, Belgrade, Serbia</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: vtrajkovic@med.bg.ac.rs</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Medicinal Research Reviews</title><title level="j" type="alt">MEDICINAL RESEARCH REVIEWS</title><idno type="ISSN">0198-6325</idno><idno type="eISSN">1098-1128</idno><imprint><biblScope unit="vol">34</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="744">744</biblScope><biblScope unit="page" to="767">767</biblScope><biblScope unit="page-count">24</biblScope><date type="published" 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She obtained a Ph.D. from the Faculty of Biology, University of Belgrade in 2012 for the work on neuroprotective potential of arylpiperazine‐based dopaminergic ligands. She is currently a postdostoral fellow at the Institute for Biological Research, University of Belgrade, and her research is focused on the role of autophagy in neuroprotection and neurodegeneration.
</desc></state><affiliation><orgName type="division">Institute for Biological Research</orgName><orgName type="institution">University of Belgrade</orgName><address><street>Despot Stefan Boulevard 142</street><postCode>11000</postCode><settlement>Belgrade</settlement><country key="RS" xml:lang="en">SERBIA</country></address></affiliation></author><author xml:id="author-0001"><persName><forename type="first">Biljana</forename><surname>Ristic</surname></persName><state type="biography"><desc><hi rend="bold">Biljana Ristic</hi> obtained her M.Sc. in Molecular Biology and Physiology at the Faculty of Biology, University of Belgrade, Serbia, in 2010. She is currently a Ph.D. candidate in Molecular Medicine at the School of Medicine, University of Belgrade. Her research is focused on the mechanisms of pharmacological autophagy induction and its role in death and survival of tumor cells.
</desc></state><affiliation><orgName type="division">Institute of Microbiology and Immunology</orgName><orgName type="division">School of Medicine</orgName><orgName type="institution">University of Belgrade</orgName><address><street>Dr. Subotica 1</street><postCode>11000</postCode><settlement>Belgrade</settlement><country key="RS" xml:lang="en">SERBIA</country></address></affiliation></author><author xml:id="author-0002"><persName><forename type="first">Marina</forename><surname>Milenkovic</surname></persName><state type="biography"><desc><hi rend="bold">Marina Milenkovic</hi> received her M.D. degree from the School of Medicine, University of Belgrade, Serbia, in 2012. She is currently a Ph.D. student in Molecular Medicine at the School of Medicine, University of Belgrade, working on the effects of chemical hypoxia and acid–base imbalance on autophagy induction in different types of malignant cells.
</desc></state><affiliation><orgName type="division">Institute of Microbiology and Immunology</orgName><orgName type="division">School of Medicine</orgName><orgName type="institution">University of Belgrade</orgName><address><street>Dr. Subotica 1</street><postCode>11000</postCode><settlement>Belgrade</settlement><country key="RS" xml:lang="en">SERBIA</country></address></affiliation></author><author xml:id="author-0003"><persName><forename type="first">Maja</forename><surname>Stanojevic</surname></persName><state type="biography"><desc><hi rend="bold">Maja Stanojevic</hi> is Associate Professor at Virology Department, Institute of Microbiology and Immunology, University of Belgrade School of Medicine, Belgrade, Serbia. She obtained a Ph.D. in Virology in 2002 at the University of Belgrade. During her postgraduate training she attended Medical Virology Course at Pasteur Institue, Paris, France, and worked as visiting scientist at Rega Institute of Medical Research KU Leuven, Leuven, Belgium, and Aristotle University, Thessaloniki, Greece. Her research interests are in fields of virus–host interactions, viral coinfections, and molecular evolution of viruses.
</desc></state><affiliation><orgName type="division">Institute of Microbiology and Immunology</orgName><orgName type="division">School of Medicine</orgName><orgName type="institution">University of Belgrade</orgName><address><street>Dr. Subotica 1</street><postCode>11000</postCode><settlement>Belgrade</settlement><country key="RS" xml:lang="en">SERBIA</country></address></affiliation></author><author xml:id="author-0004" role="corresp"><persName><forename type="first">Vladimir</forename><surname>Trajkovic</surname></persName><state type="biography"><desc><hi rend="bold">Vladimir Trajkovic</hi> is Professor of Immunology at University of Belgrade School of Medicine in Belgrade, Serbia. He obtained a Ph.D. in Immunology in 2001 at the University of Belgrade and completed his postdoctoral training in regulation of immune response at Glasgow University, UK, and International Centre for Genetic Engineering and Biotechnology, New Delhi, India. His research interests include the mechanisms of autophagy induction and the role of autophagic response in regulation of cell death and survival in cancer, neurodegeneration, and immune response/infection.
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<ref target="http://www.tei-c.org/">We use TEI</ref></desc></application></appInfo></encodingDesc><profileDesc><abstract style="main"><head>Abstract</head><p>Macroautophagy (hereafter referred to as autophagy) is an evolutionary conserved catabolic process in which the cytoplasmic content is sequestered and degraded by the lysosomal machinery in order to maintain cellular homeostasis or provide energy during metabolic and hypoxic stress. It also represents an important component of the host response against infectious agents, performing surveillance and effector functions involved in detection and clearance of pathogens, including viruses. Moreover, it appears that autophagy plays a major role in determining the fate of both virally infected and uninfected cells by blocking or promoting their death in a virus‐ and cell‐type‐dependent manner. We here review the current knowledge on the complex involvement of autophagy in survival and death of the host cells during viral infection, focusing on the molecular mechanisms underlying viral modulation of autophagic response and its interference with the cell death pathways. We also discuss a possible significance of the autophagy‐dependent modulation of cell death for the outcome and therapy of viral infections, emphasizing the need for a time‐ and cell‐type‐dependent fine‐tuning of the autophagic response in achieving an optimal balance between beneficial and adverse effects.</p></abstract><textClass><keywords><term xml:id="med21303-kwd-0001">autophagy</term><term xml:id="med21303-kwd-0002">virus</term><term xml:id="med21303-kwd-0003">cell death</term><term xml:id="med21303-kwd-0004">apoptosis</term><term xml:id="med21303-kwd-0005">therapy</term></keywords><keywords rend="articleCategory"><term>Review Article</term></keywords><keywords rend="tocHeading1"><term>Review Articles</term></keywords></textClass><langUsage><language ident="en"></language></langUsage></profileDesc><revisionDesc><change when="2019-12-20" who="#istex" xml:id="pub2tei">formatting</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-6LTJWFXN-B/fulltext.txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en" xml:id="med21303"><header><publicationMeta level="product"><doi origin="wiley" registered="yes">10.1002/(ISSN)1098-1128</doi><issn type="print">0198-6325</issn><issn type="electronic">1098-1128</issn><idGroup><id type="product" value="MED"></id></idGroup><titleGroup><title type="main" sort="MEDICINAL RESEARCH REVIEWS">Medicinal Research Reviews</title><title type="short">Med. Res. Rev.</title></titleGroup></publicationMeta><publicationMeta level="part" position="07104"><doi>10.1002/med.2014.34.issue-4</doi><copyright ownership="publisher">Copyright © 2014 Wiley Periodicals, Inc.</copyright><numberingGroup><numbering type="journalVolume" number="34">34</numbering><numbering type="journalIssue">4</numbering></numberingGroup><coverDate startDate="2014-07">July 2014</coverDate></publicationMeta><publicationMeta level="unit" position="30" type="reviewArticle" status="forIssue"><doi origin="wiley">10.1002/med.21303</doi><idGroup><id type="unit" value="MED21303"></id></idGroup><countGroup><count type="pageTotal" number="24"></count></countGroup><titleGroup><title type="articleCategory">Review Article</title><title type="tocHeading1">Review Articles</title></titleGroup><copyright ownership="publisher">© 2013 Wiley Periodicals, Inc.</copyright><eventGroup><event type="xmlCreated" agent="Aptara" date="2013-09-17"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.3.1 mode:FullText" date="2014-06-04"></event><event type="publishedOnlineEarlyUnpaginated" date="2013-09-30"></event><event type="firstOnline" date="2013-09-30"></event><event type="publishedOnlineFinalForm" date="2014-06-04"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.6.4 mode:FullText" date="2015-10-07"></event></eventGroup><numberingGroup><numbering type="pageFirst">744</numbering><numbering type="pageLast">767</numbering></numberingGroup><correspondenceTo><i>Correspondence to</i>: Vladimir Trajkovic, Institute of Microbiology and Immunology, School of Medicine, University of Belgrade, Dr. Subotica 1, 11000 Belgrade, Serbia. E‐mail: <email>vtrajkovic@med.bg.ac.rs</email>.</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:MED.MED21303.pdf"></link></linkGroup></publicationMeta><contentMeta><titleGroup><title type="main">The Role and Therapeutic Potential of Autophagy Modulation in Controlling Virus‐Induced Cell Death</title><title type="shortAuthors">TOVILOVIC ET AL.</title><title type="short">AUTOPHAGY IN VIRUS‐INDUCED CELL DEATH</title></titleGroup><creators><creator xml:id="med21303-cr-0001" creatorRole="author" affiliationRef="#med21303-aff-0001"><personName><givenNames>Gordana</givenNames><familyName>Tovilovic</familyName></personName><biographyInfo xml:id="med21303-biog-0001"><p><b>Gordana Tovilovic</b> graduated from the Faculty of Pharmacy, University of Belgrade, Serbia, in 2002, where she earned an M.Sc. degree in 2007. She obtained a Ph.D. from the Faculty of Biology, University of Belgrade in 2012 for the work on neuroprotective potential of arylpiperazine‐based dopaminergic ligands. She is currently a postdostoral fellow at the Institute for Biological Research, University of Belgrade, and her research is focused on the role of autophagy in neuroprotection and neurodegeneration.</p></biographyInfo></creator><creator xml:id="med21303-cr-0002" creatorRole="author" affiliationRef="#med21303-aff-0002"><personName><givenNames>Biljana</givenNames><familyName>Ristic</familyName></personName><biographyInfo xml:id="med21303-biog-0002"><p><b>Biljana Ristic</b> obtained her M.Sc. in Molecular Biology and Physiology at the Faculty of Biology, University of Belgrade, Serbia, in 2010. She is currently a Ph.D. candidate in Molecular Medicine at the School of Medicine, University of Belgrade. Her research is focused on the mechanisms of pharmacological autophagy induction and its role in death and survival of tumor cells.</p></biographyInfo></creator><creator xml:id="med21303-cr-0003" creatorRole="author" affiliationRef="#med21303-aff-0002"><personName><givenNames>Marina</givenNames><familyName>Milenkovic</familyName></personName><biographyInfo xml:id="med21303-biog-0003"><p><b>Marina Milenkovic</b> received her M.D. degree from the School of Medicine, University of Belgrade, Serbia, in 2012. She is currently a Ph.D. student in Molecular Medicine at the School of Medicine, University of Belgrade, working on the effects of chemical hypoxia and acid–base imbalance on autophagy induction in different types of malignant cells.</p></biographyInfo></creator><creator xml:id="med21303-cr-0004" creatorRole="author" affiliationRef="#med21303-aff-0002"><personName><givenNames>Maja</givenNames><familyName>Stanojevic</familyName></personName><biographyInfo xml:id="med21303-biog-0004"><p><b>Maja Stanojevic</b> is Associate Professor at Virology Department, Institute of Microbiology and Immunology, University of Belgrade School of Medicine, Belgrade, Serbia. She obtained a Ph.D. in Virology in 2002 at the University of Belgrade. During her postgraduate training she attended Medical Virology Course at Pasteur Institue, Paris, France, and worked as visiting scientist at Rega Institute of Medical Research KU Leuven, Leuven, Belgium, and Aristotle University, Thessaloniki, Greece. Her research interests are in fields of virus–host interactions, viral coinfections, and molecular evolution of viruses.</p></biographyInfo></creator><creator xml:id="med21303-cr-0005" creatorRole="author" affiliationRef="#med21303-aff-0002" corresponding="yes"><personName><givenNames>Vladimir</givenNames><familyName>Trajkovic</familyName></personName><biographyInfo xml:id="med21303-biog-0005"><p><b>Vladimir Trajkovic</b> is Professor of Immunology at University of Belgrade School of Medicine in Belgrade, Serbia. He obtained a Ph.D. in Immunology in 2001 at the University of Belgrade and completed his postdoctoral training in regulation of immune response at Glasgow University, UK, and International Centre for Genetic Engineering and Biotechnology, New Delhi, India. His research interests include the mechanisms of autophagy induction and the role of autophagic response in regulation of cell death and survival in cancer, neurodegeneration, and immune response/infection.</p></biographyInfo></creator></creators><affiliationGroup><affiliation xml:id="med21303-aff-0001" countryCode="RS"><orgDiv>Institute for Biological Research</orgDiv><orgName>University of Belgrade</orgName><address><street>Despot Stefan Boulevard 142</street><postCode>11000</postCode><city>Belgrade</city><country>Serbia</country></address></affiliation><affiliation xml:id="med21303-aff-0002" countryCode="RS"><orgDiv>Institute of Microbiology and Immunology</orgDiv><orgDiv>School of Medicine</orgDiv><orgName>University of Belgrade</orgName><address><street>Dr. Subotica 1</street><postCode>11000</postCode><city>Belgrade</city><country>Serbia</country></address></affiliation></affiliationGroup><keywordGroup type="author"><keyword xml:id="med21303-kwd-0001">autophagy</keyword><keyword xml:id="med21303-kwd-0002">virus</keyword><keyword xml:id="med21303-kwd-0003">cell death</keyword><keyword xml:id="med21303-kwd-0004">apoptosis</keyword><keyword xml:id="med21303-kwd-0005">therapy</keyword></keywordGroup><fundingInfo><fundingAgency>Ministry of Education, Science and Technology of the Republic of Serbia</fundingAgency><fundingNumber>41025</fundingNumber><fundingNumber>175024</fundingNumber></fundingInfo><abstractGroup><abstract type="main"><title type="main">Abstract</title><p>Macroautophagy (hereafter referred to as autophagy) is an evolutionary conserved catabolic process in which the cytoplasmic content is sequestered and degraded by the lysosomal machinery in order to maintain cellular homeostasis or provide energy during metabolic and hypoxic stress. It also represents an important component of the host response against infectious agents, performing surveillance and effector functions involved in detection and clearance of pathogens, including viruses. Moreover, it appears that autophagy plays a major role in determining the fate of both virally infected and uninfected cells by blocking or promoting their death in a virus‐ and cell‐type‐dependent manner. We here review the current knowledge on the complex involvement of autophagy in survival and death of the host cells during viral infection, focusing on the molecular mechanisms underlying viral modulation of autophagic response and its interference with the cell death pathways. We also discuss a possible significance of the autophagy‐dependent modulation of cell death for the outcome and therapy of viral infections, emphasizing the need for a time‐ and cell‐type‐dependent fine‐tuning of the autophagic response in achieving an optimal balance between beneficial and adverse effects.</p></abstract></abstractGroup></contentMeta><noteGroup><note xml:id="med21303-note-0001" numbered="no"><p>Contract grant sponsor: Ministry of Education, Science and Technology of the Republic of Serbia; Contract grant numbers: 41025 and 175024.</p></note></noteGroup></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>The Role and Therapeutic Potential of Autophagy Modulation in Controlling Virus‐Induced Cell Death</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>AUTOPHAGY IN VIRUS‐INDUCED CELL DEATH</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>The Role and Therapeutic Potential of Autophagy Modulation in Controlling Virus‐Induced Cell Death</title></titleInfo><name type="personal"><namePart type="given">Gordana</namePart><namePart type="family">Tovilovic</namePart><affiliation>Institute for Biological Research, University of Belgrade, Despot Stefan Boulevard 142, 11000, Belgrade, Serbia</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Biljana</namePart><namePart type="family">Ristic</namePart><affiliation>Institute of Microbiology and Immunology, School of Medicine, University of Belgrade, Dr. Subotica 1, 11000, Belgrade, Serbia</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Marina</namePart><namePart type="family">Milenkovic</namePart><affiliation>Institute of Microbiology and Immunology, School of Medicine, University of Belgrade, Dr. Subotica 1, 11000, Belgrade, Serbia</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Maja</namePart><namePart type="family">Stanojevic</namePart><affiliation>Institute of Microbiology and Immunology, School of Medicine, University of Belgrade, Dr. Subotica 1, 11000, Belgrade, Serbia</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Vladimir</namePart><namePart type="family">Trajkovic</namePart><affiliation>Institute of Microbiology and Immunology, School of Medicine, University of Belgrade, Dr. Subotica 1, 11000, Belgrade, Serbia</affiliation><affiliation>E-mail: vtrajkovic@med.bg.ac.rs</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="review-article" displayLabel="reviewArticle" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-L5L7X3NF-P">review-article</genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><dateIssued encoding="w3cdtf">2014-07</dateIssued><dateCreated encoding="w3cdtf">2013-09-17</dateCreated><copyrightDate encoding="w3cdtf">2014</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><abstract>Macroautophagy (hereafter referred to as autophagy) is an evolutionary conserved catabolic process in which the cytoplasmic content is sequestered and degraded by the lysosomal machinery in order to maintain cellular homeostasis or provide energy during metabolic and hypoxic stress. It also represents an important component of the host response against infectious agents, performing surveillance and effector functions involved in detection and clearance of pathogens, including viruses. Moreover, it appears that autophagy plays a major role in determining the fate of both virally infected and uninfected cells by blocking or promoting their death in a virus‐ and cell‐type‐dependent manner. We here review the current knowledge on the complex involvement of autophagy in survival and death of the host cells during viral infection, focusing on the molecular mechanisms underlying viral modulation of autophagic response and its interference with the cell death pathways. We also discuss a possible significance of the autophagy‐dependent modulation of cell death for the outcome and therapy of viral infections, emphasizing the need for a time‐ and cell‐type‐dependent fine‐tuning of the autophagic response in achieving an optimal balance between beneficial and adverse effects.</abstract><note type="funding">Ministry of Education, Science and Technology of the Republic of Serbia - No. 41025; No. 175024; </note><subject><genre>keywords</genre><topic>autophagy</topic><topic>virus</topic><topic>cell death</topic><topic>apoptosis</topic><topic>therapy</topic></subject><relatedItem type="host"><titleInfo><title>Medicinal Research Reviews</title></titleInfo><titleInfo type="abbreviated"><title>Med. Res. Rev.</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><subject><genre>article-category</genre><topic>Review Article</topic><topic>Review Articles</topic></subject><identifier type="ISSN">0198-6325</identifier><identifier type="eISSN">1098-1128</identifier><identifier type="DOI">10.1002/(ISSN)1098-1128</identifier><identifier type="PublisherID">MED</identifier><part><date>2014</date><detail type="volume"><caption>vol.</caption><number>34</number></detail><detail type="issue"><caption>no.</caption><number>4</number></detail><extent unit="pages"><start>744</start><end>767</end><total>24</total></extent></part></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0001"><titleInfo><title>Mammalian autophagy: Core molecular machinery and signaling regulation</title></titleInfo><name type="personal"><namePart type="given">Z</namePart><namePart type="family">Yang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">DJ</namePart><namePart type="family">Klionsky</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Yang Z, Klionsky DJ. Mammalian autophagy: Core molecular machinery and signaling regulation. Curr Opin Cell Biol 2010;22:124–131.</note><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>22</number></detail><extent unit="pages"><start>124</start><end>131</end></extent></part><relatedItem type="host"><titleInfo><title>Curr Opin Cell Biol</title></titleInfo><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>22</number></detail><extent unit="pages"><start>124</start><end>131</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0002"><titleInfo><title>Overview of macroautophagy regulation in mammalian cells</title></titleInfo><name type="personal"><namePart type="given">M</namePart><namePart type="family">Mehrpour</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Esclatine</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">I</namePart><namePart type="family">Beau</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Codogno</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Mehrpour M, Esclatine A, Beau I, Codogno P. Overview of macroautophagy regulation in mammalian cells. Cell Res 2010;20:748–762.</note><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>20</number></detail><extent unit="pages"><start>748</start><end>762</end></extent></part><relatedItem type="host"><titleInfo><title>Cell Res</title></titleInfo><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>20</number></detail><extent unit="pages"><start>748</start><end>762</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0003"><titleInfo><title>Autophagy and the integrated stress response</title></titleInfo><name type="personal"><namePart type="given">G</namePart><namePart type="family">Kroemer</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Marino</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Levine</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Kroemer G, Marino G, Levine B. Autophagy and the integrated stress response. Mol Cell 2010;40:280–293.</note><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>40</number></detail><extent unit="pages"><start>280</start><end>293</end></extent></part><relatedItem type="host"><titleInfo><title>Mol Cell</title></titleInfo><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>40</number></detail><extent unit="pages"><start>280</start><end>293</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0004"><titleInfo><title>Mitochondrial autophagy in neural function, neurodegenerative disease, neuron cell death, and aging</title></titleInfo><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Batlevi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">AR</namePart><namePart type="family">La Spada</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Batlevi Y, La Spada AR. Mitochondrial autophagy in neural function, neurodegenerative disease, neuron cell death, and aging. Neurobiol Dis 2011;43:46–51.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>43</number></detail><extent unit="pages"><start>46</start><end>51</end></extent></part><relatedItem type="host"><titleInfo><title>Neurobiol Dis</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>43</number></detail><extent unit="pages"><start>46</start><end>51</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0005"><titleInfo><title>Autophagy in immunity and inflammation</title></titleInfo><name type="personal"><namePart type="given">B</namePart><namePart type="family">Levine</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">N</namePart><namePart type="family">Mizushima</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">HW</namePart><namePart type="family">Virgin</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Levine B, Mizushima N, Virgin HW. Autophagy in immunity and inflammation. Nature 2011;469:323–335.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>469</number></detail><extent unit="pages"><start>323</start><end>335</end></extent></part><relatedItem type="host"><titleInfo><title>Nature</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>469</number></detail><extent unit="pages"><start>323</start><end>335</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0006"><titleInfo><title>Autophagy in cardiovascular disease</title></titleInfo><name type="personal"><namePart type="given">W</namePart><namePart type="family">Martinet</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MW</namePart><namePart type="family">Knaapen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MM</namePart><namePart type="family">Kockx</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">GR</namePart><namePart type="family">De Meyer</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Martinet W, Knaapen MW, Kockx MM, De Meyer GR. Autophagy in cardiovascular disease. Trends Mol Med 2007;13:482–491.</note><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>13</number></detail><extent unit="pages"><start>482</start><end>491</end></extent></part><relatedItem type="host"><titleInfo><title>Trends Mol Med</title></titleInfo><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>13</number></detail><extent unit="pages"><start>482</start><end>491</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0007"><titleInfo><title>Autophagy as a second level protective process in conferring resistance to environmentally‐induced oxidative stress</title></titleInfo><name type="personal"><namePart type="given">MN</namePart><namePart type="family">Moore</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Moore MN. Autophagy as a second level protective process in conferring resistance to environmentally‐induced oxidative stress. Autophagy 2008;4:254–256.</note><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>4</number></detail><extent unit="pages"><start>254</start><end>256</end></extent></part><relatedItem type="host"><titleInfo><title>Autophagy</title></titleInfo><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>4</number></detail><extent unit="pages"><start>254</start><end>256</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0008"><titleInfo><title>Mapping autophagy on to your metabolic radar</title></titleInfo><name type="personal"><namePart type="given">E</namePart><namePart type="family">Yamada</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Singh</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Yamada E, Singh R. Mapping autophagy on to your metabolic radar. Diabetes 2012;61:272–280.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>61</number></detail><extent unit="pages"><start>272</start><end>280</end></extent></part><relatedItem type="host"><titleInfo><title>Diabetes</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>61</number></detail><extent unit="pages"><start>272</start><end>280</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0009"><titleInfo><title>Interconnections between apoptotic, autophagic and necrotic pathways: Implications for cancer therapy development</title></titleInfo><name type="personal"><namePart type="given">MV</namePart><namePart type="family">Jain</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">AM</namePart><namePart type="family">Paczulla</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Klonisch</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">FN</namePart><namePart type="family">Dimgba</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SB</namePart><namePart type="family">Rao</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Roberg</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F</namePart><namePart type="family">Schweizer</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Lengerke</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Davoodpour</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">VR</namePart><namePart type="family">Palicharla</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Maddika</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Los</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Jain MV, Paczulla AM, Klonisch T, Dimgba FN, Rao SB, Roberg K, Schweizer F, Lengerke C, Davoodpour P, Palicharla VR, Maddika S, Los M. Interconnections between apoptotic, autophagic and necrotic pathways: Implications for cancer therapy development. J Cell Mol Med 2013;17:12–29.</note><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>17</number></detail><extent unit="pages"><start>12</start><end>29</end></extent></part><relatedItem type="host"><titleInfo><title>J Cell Mol Med</title></titleInfo><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>17</number></detail><extent unit="pages"><start>12</start><end>29</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0010"><titleInfo><title>Autophagy and cell death</title></titleInfo><name type="personal"><namePart type="given">D</namePart><namePart type="family">Gozuacik</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Kimchi</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Gozuacik D, Kimchi A. Autophagy and cell death. Curr Top Dev Biol 2007;78:217–245.</note><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>78</number></detail><extent unit="pages"><start>217</start><end>245</end></extent></part><relatedItem type="host"><titleInfo><title>Curr Top Dev Biol</title></titleInfo><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>78</number></detail><extent unit="pages"><start>217</start><end>245</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0011"><titleInfo><title>Autophagy in infection</title></titleInfo><name type="personal"><namePart type="given">V</namePart><namePart type="family">Deretic</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Deretic V. Autophagy in infection. Curr Opin Cell Biol 2010;22:252–262.</note><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>22</number></detail><extent unit="pages"><start>252</start><end>262</end></extent></part><relatedItem type="host"><titleInfo><title>Curr Opin Cell Biol</title></titleInfo><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>22</number></detail><extent unit="pages"><start>252</start><end>262</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0012"><titleInfo><title>Viruses and autophagy</title></titleInfo><name type="personal"><namePart type="given">SB</namePart><namePart type="family">Kudchodkar</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Levine</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Kudchodkar SB, Levine B. Viruses and autophagy. Rev Med Virol 2009;19:359–378.</note><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>19</number></detail><extent unit="pages"><start>359</start><end>378</end></extent></part><relatedItem type="host"><titleInfo><title>Rev Med Virol</title></titleInfo><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>19</number></detail><extent unit="pages"><start>359</start><end>378</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0013"><titleInfo><title>Viral proteins targeting mitochondria: Controlling cell death</title></titleInfo><name type="personal"><namePart type="given">P</namePart><namePart type="family">Boya</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">AL</namePart><namePart type="family">Pauleau</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">Poncet</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">RA</namePart><namePart type="family">Gonzalez‐Polo</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">N</namePart><namePart type="family">Zamzami</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Kroemer</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Boya P, Pauleau AL, Poncet D, Gonzalez‐Polo RA, Zamzami N, Kroemer G. Viral proteins targeting mitochondria: Controlling cell death. Biochim Biophys Acta 2004;1659:178–189.</note><part><date>2004</date><detail type="volume"><caption>vol.</caption><number>1659</number></detail><extent unit="pages"><start>178</start><end>189</end></extent></part><relatedItem type="host"><titleInfo><title>Biochim Biophys Acta</title></titleInfo><part><date>2004</date><detail type="volume"><caption>vol.</caption><number>1659</number></detail><extent unit="pages"><start>178</start><end>189</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0014"><titleInfo><title>Virus‐induced neuronal apoptosis as pathological and protective responses of the host</title></titleInfo><name type="personal"><namePart type="given">I</namePart><namePart type="family">Mori</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Nishiyama</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Yokochi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Kimura</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Mori I, Nishiyama Y, Yokochi T, Kimura Y. Virus‐induced neuronal apoptosis as pathological and protective responses of the host. Rev Med Virol 2004;14:209–216.</note><part><date>2004</date><detail type="volume"><caption>vol.</caption><number>14</number></detail><extent unit="pages"><start>209</start><end>216</end></extent></part><relatedItem type="host"><titleInfo><title>Rev Med Virol</title></titleInfo><part><date>2004</date><detail type="volume"><caption>vol.</caption><number>14</number></detail><extent unit="pages"><start>209</start><end>216</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0015"><titleInfo><title>Autophagy in HIV‐induced T cell death</title></titleInfo><name type="personal"><namePart type="given">L</namePart><namePart type="family">Espert</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Biard‐Piechaczyk</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Espert L, Biard‐Piechaczyk M. Autophagy in HIV‐induced T cell death. Curr Top Microbiol Immunol 2009;335:307–321.</note><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>335</number></detail><extent unit="pages"><start>307</start><end>321</end></extent></part><relatedItem type="host"><titleInfo><title>Curr Top Microbiol Immunol</title></titleInfo><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>335</number></detail><extent unit="pages"><start>307</start><end>321</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0016"><titleInfo><title>Silencing T cells or T‐cell silencing: Concepts in virus‐induced immunosuppression</title></titleInfo><name type="personal"><namePart type="given">S</namePart><namePart type="family">Schneider‐Schaulies</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">U</namePart><namePart type="family">Dittmer</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Schneider‐Schaulies S, Dittmer U. Silencing T cells or T‐cell silencing: Concepts in virus‐induced immunosuppression. J Gen Virol 2006;87:1423–1438.</note><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>87</number></detail><extent unit="pages"><start>1423</start><end>1438</end></extent></part><relatedItem type="host"><titleInfo><title>J Gen Virol</title></titleInfo><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>87</number></detail><extent unit="pages"><start>1423</start><end>1438</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0017"><titleInfo><title>Involvement of autophagy in viral infections: Antiviral function and subversion by viruses</title></titleInfo><name type="personal"><namePart type="given">L</namePart><namePart type="family">Espert</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Codogno</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Biard‐Piechaczyk</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Espert L, Codogno P, Biard‐Piechaczyk M. Involvement of autophagy in viral infections: Antiviral function and subversion by viruses. J Mol Med (Berl) 2007;85:811–823.</note><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>85</number></detail><extent unit="pages"><start>811</start><end>823</end></extent></part><relatedItem type="host"><titleInfo><title>J Mol Med (Berl)</title></titleInfo><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>85</number></detail><extent unit="pages"><start>811</start><end>823</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0018"><titleInfo><title>Manipulation or capitulation: Virus interactions with autophagy</title></titleInfo><name type="personal"><namePart type="given">TX</namePart><namePart type="family">Jordan</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Randall</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Jordan TX, Randall G. Manipulation or capitulation: Virus interactions with autophagy. Microbes Infect 2012;14:126–139.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>14</number></detail><extent unit="pages"><start>126</start><end>139</end></extent></part><relatedItem type="host"><titleInfo><title>Microbes Infect</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>14</number></detail><extent unit="pages"><start>126</start><end>139</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0019"><titleInfo><title>Viral evasion of autophagy</title></titleInfo><name type="personal"><namePart type="given">A</namePart><namePart type="family">Orvedahl</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Levine</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Orvedahl A, Levine B. Viral evasion of autophagy. Autophagy 2008;4:280–285.</note><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>4</number></detail><extent unit="pages"><start>280</start><end>285</end></extent></part><relatedItem type="host"><titleInfo><title>Autophagy</title></titleInfo><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>4</number></detail><extent unit="pages"><start>280</start><end>285</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0020"><titleInfo><title>Autophagy in antiviral innate immunity</title></titleInfo><name type="personal"><namePart type="given">C</namePart><namePart type="family">Richetta</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Faure</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Richetta C, Faure M. Autophagy in antiviral innate immunity. Cell Microbiol 2013;15:368–376.</note><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>15</number></detail><extent unit="pages"><start>368</start><end>376</end></extent></part><relatedItem type="host"><titleInfo><title>Cell Microbiol</title></titleInfo><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>15</number></detail><extent unit="pages"><start>368</start><end>376</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0021"><titleInfo><title>Autophagy, antiviral immunity, and viral countermeasures</title></titleInfo><name type="personal"><namePart type="given">S</namePart><namePart type="family">Shoji‐Kawata</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Levine</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Shoji‐Kawata S, Levine B. Autophagy, antiviral immunity, and viral countermeasures. Biochim Biophys Acta 2009;1793:1478–1484.</note><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>1793</number></detail><extent unit="pages"><start>1478</start><end>1484</end></extent></part><relatedItem type="host"><titleInfo><title>Biochim Biophys Acta</title></titleInfo><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>1793</number></detail><extent unit="pages"><start>1478</start><end>1484</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0022"><titleInfo><title>Autophagy in viral replication and pathogenesis</title></titleInfo><name type="personal"><namePart type="given">D</namePart><namePart type="family">Sir</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JH</namePart><namePart type="family">Ou</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Sir D, Ou JH. Autophagy in viral replication and pathogenesis. Mol Cells 2010;29:1–7.</note><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>29</number></detail><extent unit="pages"><start>1</start><end>7</end></extent></part><relatedItem type="host"><titleInfo><title>Mol Cells</title></titleInfo><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>29</number></detail><extent unit="pages"><start>1</start><end>7</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0023"><titleInfo><title>Aggresomes and autophagy generate sites for virus replication</title></titleInfo><name type="personal"><namePart type="given">T</namePart><namePart type="family">Wileman</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Wileman T. Aggresomes and autophagy generate sites for virus replication. Science 2006;312:875–878.</note><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>312</number></detail><extent unit="pages"><start>875</start><end>878</end></extent></part><relatedItem type="host"><titleInfo><title>Science</title></titleInfo><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>312</number></detail><extent unit="pages"><start>875</start><end>878</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0024"><titleInfo><title>Herpesviruses and autophagy: Catch me if you can!</title></titleInfo><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Cavignac</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Esclatine</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Cavignac Y, Esclatine A. Herpesviruses and autophagy: Catch me if you can! Viruses 2010;2:314–333.</note><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>2</number></detail><extent unit="pages"><start>314</start><end>333</end></extent></part><relatedItem type="host"><titleInfo><title>Viruses</title></titleInfo><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>2</number></detail><extent unit="pages"><start>314</start><end>333</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0025"><titleInfo><title>Autophagy and viruses: Adversaries or allies?</title></titleInfo><name type="personal"><namePart type="given">X</namePart><namePart type="family">Dong</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Levine</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Dong X, Levine B. Autophagy and viruses: Adversaries or allies? J Innate Immun 2013;5:480–493.</note><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>5</number></detail><extent unit="pages"><start>480</start><end>493</end></extent></part><relatedItem type="host"><titleInfo><title>J Innate Immun</title></titleInfo><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>5</number></detail><extent unit="pages"><start>480</start><end>493</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0026"><titleInfo><title>Guidelines for the use and interpretation of assays for monitoring autophagy</title></titleInfo><name type="personal"><namePart type="given">DJ</namePart><namePart type="family">Klionsky</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">FC</namePart><namePart type="family">Abdalla</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">H</namePart><namePart type="family">Abeliovich</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">RT</namePart><namePart type="family">Abraham</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Acevedo‐Arozena</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Adeli</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo‐Arozena A, Adeli K, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012;8:445–544. http://www.ncbi.nlm.nih.gov/pubmed/?term=Autophagy+2012%3B8%3A445%E2%80%93544</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>8</number></detail><extent unit="pages"><start>445</start><end>544</end></extent></part><relatedItem type="host"><titleInfo><title>Autophagy</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>8</number></detail><extent unit="pages"><start>445</start><end>544</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0027"><titleInfo><title>Regulation of macroautophagy by mTOR and Beclin 1 complexes</title></titleInfo><name type="personal"><namePart type="given">S</namePart><namePart type="family">Pattingre</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Espert</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Biard‐Piechaczyk</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Codogno</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Pattingre S, Espert L, Biard‐Piechaczyk M, Codogno P. Regulation of macroautophagy by mTOR and Beclin 1 complexes. Biochimie 2008;90:313–323.</note><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>90</number></detail><extent unit="pages"><start>313</start><end>323</end></extent></part><relatedItem type="host"><titleInfo><title>Biochimie</title></titleInfo><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>90</number></detail><extent unit="pages"><start>313</start><end>323</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0028"><titleInfo><title>Role of AMPK‐mTOR‐Ulk1/2 in the regulation of autophagy: Cross talk, shortcuts, and feedbacks</title></titleInfo><name type="personal"><namePart type="given">S</namePart><namePart type="family">Alers</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">AS</namePart><namePart type="family">Loffler</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Wesselborg</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Stork</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Alers S, Loffler AS, Wesselborg S, Stork B. Role of AMPK‐mTOR‐Ulk1/2 in the regulation of autophagy: Cross talk, shortcuts, and feedbacks. Mol Cell Biol 2012;32:2–11.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>32</number></detail><extent unit="pages"><start>2</start><end>11</end></extent></part><relatedItem type="host"><titleInfo><title>Mol Cell Biol</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>32</number></detail><extent unit="pages"><start>2</start><end>11</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0029"><titleInfo><title>Compound C induces protective autophagy in cancer cells through AMPK inhibition‐independent blockade of Akt/mTOR pathway</title></titleInfo><name type="personal"><namePart type="given">L</namePart><namePart type="family">Vucicevic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Misirkic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Janjetovic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">U</namePart><namePart type="family">Vilimanovich</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E</namePart><namePart type="family">Sudar</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E</namePart><namePart type="family">Isenovic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Prica</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Harhaji‐Trajkovic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Kravic‐Stevovic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">V</namePart><namePart type="family">Bumbasirevic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">V</namePart><namePart type="family">Trajkovic</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Vucicevic L, Misirkic M, Janjetovic K, Vilimanovich U, Sudar E, Isenovic E, Prica M, Harhaji‐Trajkovic L, Kravic‐Stevovic T, Bumbasirevic V, Trajkovic V. Compound C induces protective autophagy in cancer cells through AMPK inhibition‐independent blockade of Akt/mTOR pathway. Autophagy 2011;7:40–50.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>7</number></detail><extent unit="pages"><start>40</start><end>50</end></extent></part><relatedItem type="host"><titleInfo><title>Autophagy</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>7</number></detail><extent unit="pages"><start>40</start><end>50</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0030"><titleInfo><title>Autophagy fights disease through cellular self‐digestion</title></titleInfo><name type="personal"><namePart type="given">N</namePart><namePart type="family">Mizushima</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Levine</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">AM</namePart><namePart type="family">Cuervo</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">DJ</namePart><namePart type="family">Klionsky</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Mizushima N, Levine B, Cuervo AM, Klionsky DJ. Autophagy fights disease through cellular self‐digestion. Nature 2008;451:1069–1075.</note><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>451</number></detail><extent unit="pages"><start>1069</start><end>1075</end></extent></part><relatedItem type="host"><titleInfo><title>Nature</title></titleInfo><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>451</number></detail><extent unit="pages"><start>1069</start><end>1075</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0031"><titleInfo><title>Virus‐triggered autophagy in viral hepatitis—Possible novel strategies for drug development</title></titleInfo><name type="personal"><namePart type="given">SM</namePart><namePart type="family">Alavian</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SR</namePart><namePart type="family">Ande</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">KM</namePart><namePart type="family">Coombs</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Yeganeh</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Davoodpour</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Hashemi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Los</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Ghavami</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Alavian SM, Ande SR, Coombs KM, Yeganeh B, Davoodpour P, Hashemi M, Los M, Ghavami S. Virus‐triggered autophagy in viral hepatitis—Possible novel strategies for drug development. J Viral Hepat 2011;18:821–830.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>18</number></detail><extent unit="pages"><start>821</start><end>830</end></extent></part><relatedItem type="host"><titleInfo><title>J Viral Hepat</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>18</number></detail><extent unit="pages"><start>821</start><end>830</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0032"><titleInfo><title>Impact of the autophagy machinery on hepatitis C virus infection</title></titleInfo><name type="personal"><namePart type="given">M</namePart><namePart type="family">Dreux</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">FV</namePart><namePart type="family">Chisari</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Dreux M, Chisari FV. Impact of the autophagy machinery on hepatitis C virus infection. Viruses 2011;3:1342–1357.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>3</number></detail><extent unit="pages"><start>1342</start><end>1357</end></extent></part><relatedItem type="host"><titleInfo><title>Viruses</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>3</number></detail><extent unit="pages"><start>1342</start><end>1357</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0033"><titleInfo><title>Dengue virus and autophagy</title></titleInfo><name type="personal"><namePart type="given">NS</namePart><namePart type="family">Heaton</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Randall</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Heaton NS, Randall G. Dengue virus and autophagy. Viruses 2011;3:1332–1341.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>3</number></detail><extent unit="pages"><start>1332</start><end>1341</end></extent></part><relatedItem type="host"><titleInfo><title>Viruses</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>3</number></detail><extent unit="pages"><start>1332</start><end>1341</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0034"><titleInfo><title>Hepatitis C virus genotype 1a growth and induction of autophagy</title></titleInfo><name type="personal"><namePart type="given">M</namePart><namePart type="family">Ait‐Goughoulte</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Kanda</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Meyer</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JS</namePart><namePart type="family">Ryerse</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">RB</namePart><namePart type="family">Ray</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Ray</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Ait‐Goughoulte M, Kanda T, Meyer K, Ryerse JS, Ray RB, Ray R. Hepatitis C virus genotype 1a growth and induction of autophagy. J Virol 2008;82:2241–2249.</note><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>82</number></detail><extent unit="pages"><start>2241</start><end>2249</end></extent></part><relatedItem type="host"><titleInfo><title>J Virol</title></titleInfo><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>82</number></detail><extent unit="pages"><start>2241</start><end>2249</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0035"><titleInfo><title>A role for autophagolysosomes in dengue virus 3 production in HepG2 cells</title></titleInfo><name type="personal"><namePart type="given">A</namePart><namePart type="family">Khakpoor</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Panyasrivanit</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">N</namePart><namePart type="family">Wikan</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">DR</namePart><namePart type="family">Smith</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Khakpoor A, Panyasrivanit M, Wikan N, Smith DR. A role for autophagolysosomes in dengue virus 3 production in HepG2 cells. J Gen Virol 2009;90:1093–1103.</note><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>90</number></detail><extent unit="pages"><start>1093</start><end>1103</end></extent></part><relatedItem type="host"><titleInfo><title>J Gen Virol</title></titleInfo><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>90</number></detail><extent unit="pages"><start>1093</start><end>1103</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0036"><titleInfo><title>Autophagy pathway intersects with HIV‐1 biosynthesis and regulates viral yields in macrophages</title></titleInfo><name type="personal"><namePart type="given">GB</namePart><namePart type="family">Kyei</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Dinkins</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">AS</namePart><namePart type="family">Davis</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E</namePart><namePart type="family">Roberts</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SB</namePart><namePart type="family">Singh</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Dong</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Wu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E</namePart><namePart type="family">Kominami</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Ueno</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Yamamoto</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Federico</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Panganiban</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">I</namePart><namePart type="family">Vergne</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">V</namePart><namePart type="family">Deretic</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Kyei GB, Dinkins C, Davis AS, Roberts E, Singh SB, Dong C, Wu L, Kominami E, Ueno T, Yamamoto A, Federico M, Panganiban A, Vergne I, Deretic V. Autophagy pathway intersects with HIV‐1 biosynthesis and regulates viral yields in macrophages. J Cell Biol 2009;186:255–268.</note><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>186</number></detail><extent unit="pages"><start>255</start><end>268</end></extent></part><relatedItem type="host"><titleInfo><title>J Cell Biol</title></titleInfo><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>186</number></detail><extent unit="pages"><start>255</start><end>268</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0037"><titleInfo><title>Subversion of cellular autophagy machinery by hepatitis B virus for viral envelopment</title></titleInfo><name type="personal"><namePart type="given">J</namePart><namePart type="family">Li</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Liu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Z</namePart><namePart type="family">Wang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Liu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Wang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Liu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">H</namePart><namePart type="family">Ding</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Z</namePart><namePart type="family">Yuan</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Li J, Liu Y, Wang Z, Liu K, Wang Y, Liu J, Ding H, Yuan Z. Subversion of cellular autophagy machinery by hepatitis B virus for viral envelopment. J Virol 2011;85:6319–6333.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>85</number></detail><extent unit="pages"><start>6319</start><end>6333</end></extent></part><relatedItem type="host"><titleInfo><title>J Virol</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>85</number></detail><extent unit="pages"><start>6319</start><end>6333</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0038"><titleInfo><title>Autophagy is involved in the early step of Japanese encephalitis virus infection</title></titleInfo><name type="personal"><namePart type="given">JK</namePart><namePart type="family">Li</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JJ</namePart><namePart type="family">Liang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">CL</namePart><namePart type="family">Liao</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">YL</namePart><namePart type="family">Lin</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Li JK, Liang JJ, Liao CL, Lin YL. Autophagy is involved in the early step of Japanese encephalitis virus infection. Microbes Infect 2012;14:159–168.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>14</number></detail><extent unit="pages"><start>159</start><end>168</end></extent></part><relatedItem type="host"><titleInfo><title>Microbes Infect</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>14</number></detail><extent unit="pages"><start>159</start><end>168</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0039"><titleInfo><title>The invasion of tobacco mosaic virus RNA induces endoplasmic reticulum stress‐related autophagy in HeLa cells</title></titleInfo><name type="personal"><namePart type="given">L</namePart><namePart type="family">Li</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Wang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Xiao</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Zhu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Li</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Liu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Yang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Z</namePart><namePart type="family">Tang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Li</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">W</namePart><namePart type="family">Huang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Chen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">X</namePart><namePart type="family">Zheng</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">He</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Tan</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Li L, Wang L, Xiao R, Zhu G, Li Y, Liu C, Yang R, Tang Z, Li J, Huang W, Chen L, Zheng X, He Y, Tan J. The invasion of tobacco mosaic virus RNA induces endoplasmic reticulum stress‐related autophagy in HeLa cells. Biosci Rep 2012;32:171–186.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>32</number></detail><extent unit="pages"><start>171</start><end>186</end></extent></part><relatedItem type="host"><titleInfo><title>Biosci Rep</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>32</number></detail><extent unit="pages"><start>171</start><end>186</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0040"><titleInfo><title>Endogenous MHC class II processing of a viral nuclear antigen after autophagy</title></titleInfo><name type="personal"><namePart type="given">C</namePart><namePart type="family">Paludan</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">Schmid</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Landthaler</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Vockerodt</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">Kube</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Tuschl</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Munz</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Paludan C, Schmid D, Landthaler M, Vockerodt M, Kube D, Tuschl T, Munz C. Endogenous MHC class II processing of a viral nuclear antigen after autophagy. Science 2005;307:593–596.</note><part><date>2005</date><detail type="volume"><caption>vol.</caption><number>307</number></detail><extent unit="pages"><start>593</start><end>596</end></extent></part><relatedItem type="host"><titleInfo><title>Science</title></titleInfo><part><date>2005</date><detail type="volume"><caption>vol.</caption><number>307</number></detail><extent unit="pages"><start>593</start><end>596</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0041"><titleInfo><title>Autophagy is involved in anti‐viral activity of pentagalloylglucose (PGG) against Herpes simplex virus type 1 infection in vitro</title></titleInfo><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Pei</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">ZP</namePart><namePart type="family">Chen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">HQ</namePart><namePart type="family">Ju</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Komatsu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">YH</namePart><namePart type="family">Ji</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Liu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">CW</namePart><namePart type="family">Guo</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">YJ</namePart><namePart type="family">Zhang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">CR</namePart><namePart type="family">Yang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">YF</namePart><namePart type="family">Wang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Kitazato</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Pei Y, Chen ZP, Ju HQ, Komatsu M, Ji YH, Liu G, Guo CW, Zhang YJ, Yang CR, Wang YF, Kitazato K. Autophagy is involved in anti‐viral activity of pentagalloylglucose (PGG) against Herpes simplex virus type 1 infection in vitro. Biochem Biophys Res Commun 2011;405:186–191.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>405</number></detail><extent unit="pages"><start>186</start><end>191</end></extent></part><relatedItem type="host"><titleInfo><title>Biochem Biophys Res Commun</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>405</number></detail><extent unit="pages"><start>186</start><end>191</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0042"><titleInfo><title>Autophagy promotes the replication of encephalomyocarditis virus in host cells</title></titleInfo><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Zhang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Z</namePart><namePart type="family">Li</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Xinna</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Xin</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">H</namePart><namePart type="family">Yang</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Zhang Y, Li Z, Xinna G, Xin G, Yang H. Autophagy promotes the replication of encephalomyocarditis virus in host cells. Autophagy 2011;7:613–628.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>7</number></detail><extent unit="pages"><start>613</start><end>628</end></extent></part><relatedItem type="host"><titleInfo><title>Autophagy</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>7</number></detail><extent unit="pages"><start>613</start><end>628</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0043"><titleInfo><title>Human immunodeficiency virus‐1 inhibition of immunoamphisomes in dendritic cells impairs early innate and adaptive immune responses</title></titleInfo><name type="personal"><namePart type="given">FP</namePart><namePart type="family">Blanchet</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Moris</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">DS</namePart><namePart type="family">Nikolic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Lehmann</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Cardinaud</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Stalder</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E</namePart><namePart type="family">Garcia</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Dinkins</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F</namePart><namePart type="family">Leuba</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Wu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">O</namePart><namePart type="family">Schwartz</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">V</namePart><namePart type="family">Deretic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">V</namePart><namePart type="family">Piguet</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Blanchet FP, Moris A, Nikolic DS, Lehmann M, Cardinaud S, Stalder R, Garcia E, Dinkins C, Leuba F, Wu L, Schwartz O, Deretic V, Piguet V. Human immunodeficiency virus‐1 inhibition of immunoamphisomes in dendritic cells impairs early innate and adaptive immune responses. Immunity 2010;32:654–669.</note><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>32</number></detail><extent unit="pages"><start>654</start><end>669</end></extent></part><relatedItem type="host"><titleInfo><title>Immunity</title></titleInfo><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>32</number></detail><extent unit="pages"><start>654</start><end>669</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0044"><titleInfo><title>Autophagy protects against Sindbis virus infection of the central nervous system</title></titleInfo><name type="personal"><namePart type="given">A</namePart><namePart type="family">Orvedahl</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">MacPherson</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Sumpter Jr.</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Z</namePart><namePart type="family">Talloczy</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Z</namePart><namePart type="family">Zou</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Levine</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Orvedahl A, MacPherson S, Sumpter R, Jr., Talloczy Z, Zou Z, Levine B. Autophagy protects against Sindbis virus infection of the central nervous system. Cell Host Microbe 2010;7:115–127.</note><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>7</number></detail><extent unit="pages"><start>115</start><end>127</end></extent></part><relatedItem type="host"><titleInfo><title>Cell Host Microbe</title></titleInfo><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>7</number></detail><extent unit="pages"><start>115</start><end>127</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0045"><titleInfo><title>Hepatitis C virus upregulates Beclin1 for induction of autophagy and activates mTOR signaling</title></titleInfo><name type="personal"><namePart type="given">S</namePart><namePart type="family">Shrivastava</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Bhanja Chowdhury</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Steele</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Ray</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">RB</namePart><namePart type="family">Ray</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Shrivastava S, Bhanja Chowdhury J, Steele R, Ray R, Ray RB. Hepatitis C virus upregulates Beclin1 for induction of autophagy and activates mTOR signaling. J Virol 2012;86:8705–8712.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>86</number></detail><extent unit="pages"><start>8705</start><end>8712</end></extent></part><relatedItem type="host"><titleInfo><title>J Virol</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>86</number></detail><extent unit="pages"><start>8705</start><end>8712</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0046"><titleInfo><title>Rab5 and class III phosphoinositide 3‐kinase Vps34 are involved in hepatitis C virus NS4B‐induced autophagy</title></titleInfo><name type="personal"><namePart type="given">WC</namePart><namePart type="family">Su</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">TC</namePart><namePart type="family">Chao</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">YL</namePart><namePart type="family">Huang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SC</namePart><namePart type="family">Weng</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">KS</namePart><namePart type="family">Jeng</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MM</namePart><namePart type="family">Lai</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Su WC, Chao TC, Huang YL, Weng SC, Jeng KS, Lai MM. Rab5 and class III phosphoinositide 3‐kinase Vps34 are involved in hepatitis C virus NS4B‐induced autophagy. J Virol 2011;85:10561–10571.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>85</number></detail><extent unit="pages"><start>10561</start><end>10571</end></extent></part><relatedItem type="host"><titleInfo><title>J Virol</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>85</number></detail><extent unit="pages"><start>10561</start><end>10571</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0047"><titleInfo><title>Newcastle disease virus triggers autophagy in U251 glioma cells to enhance virus replication</title></titleInfo><name type="personal"><namePart type="given">C</namePart><namePart type="family">Meng</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Z</namePart><namePart type="family">Zhou</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Jiang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Yu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Jia</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Wu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Liu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Meng</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Ding</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Meng C, Zhou Z, Jiang K, Yu S, Jia L, Wu Y, Liu Y, Meng S, Ding C. Newcastle disease virus triggers autophagy in U251 glioma cells to enhance virus replication. Arch Virol 2012;157:1011–1018.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>157</number></detail><extent unit="pages"><start>1011</start><end>1018</end></extent></part><relatedItem type="host"><titleInfo><title>Arch Virol</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>157</number></detail><extent unit="pages"><start>1011</start><end>1018</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0048"><titleInfo><title>Bovine herpesvirus type 4 infection modulates autophagy in a permissive cell line</title></titleInfo><name type="personal"><namePart type="given">S</namePart><namePart type="family">Montagnaro</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Ciarcia</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F</namePart><namePart type="family">Pagnini</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">De Martino</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MV</namePart><namePart type="family">Puzio</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">GE</namePart><namePart type="family">Granato</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F</namePart><namePart type="family">Avino</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">U</namePart><namePart type="family">Pagnini</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Iovane</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Giordano</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Montagnaro S, Ciarcia R, Pagnini F, De Martino L, Puzio MV, Granato GE, Avino F, Pagnini U, Iovane G, Giordano A. Bovine herpesvirus type 4 infection modulates autophagy in a permissive cell line. J Cell Biochem 2013;114:1529–1535.</note><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>114</number></detail><extent unit="pages"><start>1529</start><end>1535</end></extent></part><relatedItem type="host"><titleInfo><title>J Cell Biochem</title></titleInfo><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>114</number></detail><extent unit="pages"><start>1529</start><end>1535</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0049"><titleInfo><title>Enterovirus 71‐induced autophagy detected in vitro and in vivo promotes viral replication</title></titleInfo><name type="personal"><namePart type="given">SC</namePart><namePart type="family">Huang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">CL</namePart><namePart type="family">Chang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">PS</namePart><namePart type="family">Wang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Tsai</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">HS</namePart><namePart type="family">Liu</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Huang SC, Chang CL, Wang PS, Tsai Y, Liu HS. Enterovirus 71‐induced autophagy detected in vitro and in vivo promotes viral replication. J Med Virol 2009;81:1241–1252.</note><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>81</number></detail><extent unit="pages"><start>1241</start><end>1252</end></extent></part><relatedItem type="host"><titleInfo><title>J Med Virol</title></titleInfo><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>81</number></detail><extent unit="pages"><start>1241</start><end>1252</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0050"><titleInfo><title>Avian influenza A virus H5N1 causes autophagy‐mediated cell death through suppression of mTOR signaling</title></titleInfo><name type="personal"><namePart type="given">J</namePart><namePart type="family">Ma</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Q</namePart><namePart type="family">Sun</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Mi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">H</namePart><namePart type="family">Zhang</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Ma J, Sun Q, Mi R, Zhang H. Avian influenza A virus H5N1 causes autophagy‐mediated cell death through suppression of mTOR signaling. J Genet Genomics 2011;38:533–537.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>38</number></detail><extent unit="pages"><start>533</start><end>537</end></extent></part><relatedItem type="host"><titleInfo><title>J Genet Genomics</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>38</number></detail><extent unit="pages"><start>533</start><end>537</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0051"><titleInfo><title>The p17 nonstructural protein of avian reovirus triggers autophagy enhancing virus replication via activation of phosphatase and tensin deleted on chromosome 10 (PTEN) and AMP‐activated protein kinase (AMPK), as well as dsRNA‐dependent protein kinase (PKR)/eIF2alpha signaling pathways</title></titleInfo><name type="personal"><namePart type="given">PI</namePart><namePart type="family">Chi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">WR</namePart><namePart type="family">Huang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">IH</namePart><namePart type="family">Lai</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">CY</namePart><namePart type="family">Cheng</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">HJ</namePart><namePart type="family">Liu</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Chi PI, Huang WR, Lai IH, Cheng CY, Liu HJ. The p17 nonstructural protein of avian reovirus triggers autophagy enhancing virus replication via activation of phosphatase and tensin deleted on chromosome 10 (PTEN) and AMP‐activated protein kinase (AMPK), as well as dsRNA‐dependent protein kinase (PKR)/eIF2alpha signaling pathways. J Biol Chem 2013;288:3571–3584.</note><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>288</number></detail><extent unit="pages"><start>3571</start><end>3584</end></extent></part><relatedItem type="host"><titleInfo><title>J Biol Chem</title></titleInfo><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>288</number></detail><extent unit="pages"><start>3571</start><end>3584</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0052"><titleInfo><title>Avian reovirus triggers autophagy in primary chicken fibroblast cells and Vero cells to promote virus production</title></titleInfo><name type="personal"><namePart type="given">S</namePart><namePart type="family">Meng</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Jiang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">X</namePart><namePart type="family">Zhang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Zhang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Z</namePart><namePart type="family">Zhou</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Hu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Yang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Sun</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Wu</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Meng S, Jiang K, Zhang X, Zhang M, Zhou Z, Hu M, Yang R, Sun C, Wu Y. Avian reovirus triggers autophagy in primary chicken fibroblast cells and Vero cells to promote virus production. Arch Virol 2012;157:661–668.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>157</number></detail><extent unit="pages"><start>661</start><end>668</end></extent></part><relatedItem type="host"><titleInfo><title>Arch Virol</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>157</number></detail><extent unit="pages"><start>661</start><end>668</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0053"><titleInfo><title>Autophagy induction by the pathogen receptor CD46</title></titleInfo><name type="personal"><namePart type="given">PE</namePart><namePart type="family">Joubert</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Meiffren</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">IP</namePart><namePart type="family">Gregoire</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Pontini</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Richetta</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Flacher</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">O</namePart><namePart type="family">Azocar</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">PO</namePart><namePart type="family">Vidalain</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Vidal</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">V</namePart><namePart type="family">Lotteau</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Codogno</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Rabourdin‐Combe</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Faure</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Joubert PE, Meiffren G, Gregoire IP, Pontini G, Richetta C, Flacher M, Azocar O, Vidalain PO, Vidal M, Lotteau V, Codogno P, Rabourdin‐Combe C, Faure M. Autophagy induction by the pathogen receptor CD46. Cell Host Microbe 2009;6:354–366.</note><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>6</number></detail><extent unit="pages"><start>354</start><end>366</end></extent></part><relatedItem type="host"><titleInfo><title>Cell Host Microbe</title></titleInfo><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>6</number></detail><extent unit="pages"><start>354</start><end>366</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0054"><titleInfo><title>Porcine circovirus type 2 induces autophagy via the AMPK/ERK/TSC2/mTOR signaling pathway in PK‐15 cells</title></titleInfo><name type="personal"><namePart type="given">B</namePart><namePart type="family">Zhu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Zhou</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F</namePart><namePart type="family">Xu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Shuai</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">X</namePart><namePart type="family">Li</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">W</namePart><namePart type="family">Fang</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Zhu B, Zhou Y, Xu F, Shuai J, Li X, Fang W. Porcine circovirus type 2 induces autophagy via the AMPK/ERK/TSC2/mTOR signaling pathway in PK‐15 cells. J Virol 2012;86:12003–12012.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>86</number></detail><extent unit="pages"><start>12003</start><end>12012</end></extent></part><relatedItem type="host"><titleInfo><title>J Virol</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>86</number></detail><extent unit="pages"><start>12003</start><end>12012</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0055"><titleInfo><title>Foot‐and‐mouth disease virus induces autophagosomes during cell entry via a class III phosphatidylinositol 3‐kinase‐independent pathway</title></titleInfo><name type="personal"><namePart type="given">S</namePart><namePart type="family">Berryman</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E</namePart><namePart type="family">Brooks</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Burman</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Hawes</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Roberts</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Netherton</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Monaghan</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Whelband</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E</namePart><namePart type="family">Cottam</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Z</namePart><namePart type="family">Elazar</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Jackson</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Wileman</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Berryman S, Brooks E, Burman A, Hawes P, Roberts R, Netherton C, Monaghan P, Whelband M, Cottam E, Elazar Z, Jackson T, Wileman T. Foot‐and‐mouth disease virus induces autophagosomes during cell entry via a class III phosphatidylinositol 3‐kinase‐independent pathway. J Virol 2012;86:12940–12953.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>86</number></detail><extent unit="pages"><start>12940</start><end>12953</end></extent></part><relatedItem type="host"><titleInfo><title>J Virol</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>86</number></detail><extent unit="pages"><start>12940</start><end>12953</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0056"><titleInfo><title>Hepatitis C virus inhibits AKT‐tuberous sclerosis complex (TSC), the mechanistic target of rapamycin (MTOR) pathway, through endoplasmic reticulum stress to induce autophagy</title></titleInfo><name type="personal"><namePart type="given">H</namePart><namePart type="family">Huang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Kang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Wang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Luo</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">W</namePart><namePart type="family">Yang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Z</namePart><namePart type="family">Zhao</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Huang H, Kang R, Wang J, Luo G, Yang W, Zhao Z. Hepatitis C virus inhibits AKT‐tuberous sclerosis complex (TSC), the mechanistic target of rapamycin (MTOR) pathway, through endoplasmic reticulum stress to induce autophagy. Autophagy 2013;9:175–195.</note><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>9</number></detail><extent unit="pages"><start>175</start><end>195</end></extent></part><relatedItem type="host"><titleInfo><title>Autophagy</title></titleInfo><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>9</number></detail><extent unit="pages"><start>175</start><end>195</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0057"><titleInfo><title>Simian virus 40 small T antigen activates AMPK and triggers autophagy to protect cancer cells from nutrient deprivation</title></titleInfo><name type="personal"><namePart type="given">SH</namePart><namePart type="family">Kumar</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Rangarajan</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Kumar SH, Rangarajan A. Simian virus 40 small T antigen activates AMPK and triggers autophagy to protect cancer cells from nutrient deprivation. J Virol 2009;83:8565–8574.</note><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>83</number></detail><extent unit="pages"><start>8565</start><end>8574</end></extent></part><relatedItem type="host"><titleInfo><title>J Virol</title></titleInfo><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>83</number></detail><extent unit="pages"><start>8565</start><end>8574</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0058"><titleInfo><title>mTOR‐independent autophagy counteracts apoptosis in herpes simplex virus type 1‐infected U251 glioma cells</title></titleInfo><name type="personal"><namePart type="given">G</namePart><namePart type="family">Tovilovic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Ristic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Siljic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">V</namePart><namePart type="family">Nikolic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Kravic‐Stevovic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Dulovic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Milenkovic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Knezevic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Bosnjak</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">V</namePart><namePart type="family">Bumbasirevic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Stanojevic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">V</namePart><namePart type="family">Trajkovic</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Tovilovic G, Ristic B, Siljic M, Nikolic V, Kravic‐Stevovic T, Dulovic M, Milenkovic M, Knezevic A, Bosnjak M, Bumbasirevic V, Stanojevic M, Trajkovic V. mTOR‐independent autophagy counteracts apoptosis in herpes simplex virus type 1‐infected U251 glioma cells. Microbes Infect 2013;15:615–624.</note><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>15</number></detail><extent unit="pages"><start>615</start><end>624</end></extent></part><relatedItem type="host"><titleInfo><title>Microbes Infect</title></titleInfo><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>15</number></detail><extent unit="pages"><start>615</start><end>624</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0059"><titleInfo><title>Regulation of starvation‐ and virus‐induced autophagy by the eIF2alpha kinase signaling pathway</title></titleInfo><name type="personal"><namePart type="given">Z</namePart><namePart type="family">Talloczy</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">W</namePart><namePart type="family">Jiang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">HWt</namePart><namePart type="family">Virgin</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">DA</namePart><namePart type="family">Leib</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">Scheuner</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">RJ</namePart><namePart type="family">Kaufman</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">EL</namePart><namePart type="family">Eskelinen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Levine</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Talloczy Z, Jiang W, Virgin HWt, Leib DA, Scheuner D, Kaufman RJ, Eskelinen EL, Levine B. Regulation of starvation‐ and virus‐induced autophagy by the eIF2alpha kinase signaling pathway. Proc Natl Acad Sci USA 2002;99:190–195.</note><part><date>2002</date><detail type="volume"><caption>vol.</caption><number>99</number></detail><extent unit="pages"><start>190</start><end>195</end></extent></part><relatedItem type="host"><titleInfo><title>Proc Natl Acad Sci USA</title></titleInfo><part><date>2002</date><detail type="volume"><caption>vol.</caption><number>99</number></detail><extent unit="pages"><start>190</start><end>195</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0060"><titleInfo><title>Autophagosome formation during varicella‐zoster virus infection following endoplasmic reticulum stress and the unfolded protein response</title></titleInfo><name type="personal"><namePart type="given">JE</namePart><namePart type="family">Carpenter</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">W</namePart><namePart type="family">Jackson</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Benetti</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Grose</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Carpenter JE, Jackson W, Benetti L, Grose C. Autophagosome formation during varicella‐zoster virus infection following endoplasmic reticulum stress and the unfolded protein response. J Virol 2011;85:9414–9424.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>85</number></detail><extent unit="pages"><start>9414</start><end>9424</end></extent></part><relatedItem type="host"><titleInfo><title>J Virol</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>85</number></detail><extent unit="pages"><start>9414</start><end>9424</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0061"><titleInfo><title>Chikungunya virus‐induced autophagy delays caspase‐dependent cell death</title></titleInfo><name type="personal"><namePart type="given">PE</namePart><namePart type="family">Joubert</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SW</namePart><namePart type="family">Werneke</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Calle</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F</namePart><namePart type="family">Guivel‐Benhassine</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Giodini</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Peduto</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Levine</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">O</namePart><namePart type="family">Schwartz</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">DJ</namePart><namePart type="family">Lenschow</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">ML</namePart><namePart type="family">Albert</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Joubert PE, Werneke SW, de la Calle C, Guivel‐Benhassine F, Giodini A, Peduto L, Levine B, Schwartz O, Lenschow DJ, Albert ML. Chikungunya virus‐induced autophagy delays caspase‐dependent cell death. J Exp Med 2012;209:1029–1047.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>209</number></detail><extent unit="pages"><start>1029</start><end>1047</end></extent></part><relatedItem type="host"><titleInfo><title>J Exp Med</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>209</number></detail><extent unit="pages"><start>1029</start><end>1047</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0062"><titleInfo><title>Activation of the unfolded protein response and autophagy after hepatitis C virus infection suppresses innate antiviral immunity in vitro</title></titleInfo><name type="personal"><namePart type="given">PY</namePart><namePart type="family">Ke</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SS</namePart><namePart type="family">Chen</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Ke PY, Chen SS. Activation of the unfolded protein response and autophagy after hepatitis C virus infection suppresses innate antiviral immunity in vitro. J Clin Invest 2011;121:37–56.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>121</number></detail><extent unit="pages"><start>37</start><end>56</end></extent></part><relatedItem type="host"><titleInfo><title>J Clin Invest</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>121</number></detail><extent unit="pages"><start>37</start><end>56</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0063"><titleInfo><title>Flavivirus NS4A‐induced autophagy protects cells against death and enhances virus replication</title></titleInfo><name type="personal"><namePart type="given">JE</namePart><namePart type="family">McLean</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Wudzinska</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E</namePart><namePart type="family">Datan</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">Quaglino</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Z</namePart><namePart type="family">Zakeri</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">McLean JE, Wudzinska A, Datan E, Quaglino D, Zakeri Z. Flavivirus NS4A‐induced autophagy protects cells against death and enhances virus replication. J Biol Chem 2011;286:22147–22159.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>286</number></detail><extent unit="pages"><start>22147</start><end>22159</end></extent></part><relatedItem type="host"><titleInfo><title>J Biol Chem</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>286</number></detail><extent unit="pages"><start>22147</start><end>22159</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0064"><titleInfo><title>Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein response</title></titleInfo><name type="personal"><namePart type="given">D</namePart><namePart type="family">Sir</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">WL</namePart><namePart type="family">Chen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Choi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Wakita</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">TS</namePart><namePart type="family">Yen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JH</namePart><namePart type="family">Ou</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Sir D, Chen WL, Choi J, Wakita T, Yen TS, Ou JH. Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein response. Hepatology 2008;48:1054–1061.</note><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>48</number></detail><extent unit="pages"><start>1054</start><end>1061</end></extent></part><relatedItem type="host"><titleInfo><title>Hepatology</title></titleInfo><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>48</number></detail><extent unit="pages"><start>1054</start><end>1061</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0065"><titleInfo><title>Early induction of autophagy in human fibroblasts after infection with human cytomegalovirus or herpes simplex virus 1</title></titleInfo><name type="personal"><namePart type="given">S</namePart><namePart type="family">McFarlane</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Aitken</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JS</namePart><namePart type="family">Sutherland</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MJ</namePart><namePart type="family">Nicholl</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">VG</namePart><namePart type="family">Preston</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">CM</namePart><namePart type="family">Preston</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">McFarlane S, Aitken J, Sutherland JS, Nicholl MJ, Preston VG, Preston CM. Early induction of autophagy in human fibroblasts after infection with human cytomegalovirus or herpes simplex virus 1. J Virol 2011;85:4212–4221.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>85</number></detail><extent unit="pages"><start>4212</start><end>4221</end></extent></part><relatedItem type="host"><titleInfo><title>J Virol</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>85</number></detail><extent unit="pages"><start>4212</start><end>4221</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0066"><titleInfo><title>The human cytomegalovirus protein TRS1 inhibits autophagy via its interaction with Beclin 1</title></titleInfo><name type="personal"><namePart type="given">M</namePart><namePart type="family">Chaumorcel</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Lussignol</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Mouna</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Cavignac</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Fahie</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Cotte‐Laffitte</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Geballe</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">W</namePart><namePart type="family">Brune</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">I</namePart><namePart type="family">Beau</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Codogno</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Esclatine</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Chaumorcel M, Lussignol M, Mouna L, Cavignac Y, Fahie K, Cotte‐Laffitte J, Geballe A, Brune W, Beau I, Codogno P, Esclatine A. The human cytomegalovirus protein TRS1 inhibits autophagy via its interaction with Beclin 1. J Virol 2012;86:2571–2584.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>86</number></detail><extent unit="pages"><start>2571</start><end>2584</end></extent></part><relatedItem type="host"><titleInfo><title>J Virol</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>86</number></detail><extent unit="pages"><start>2571</start><end>2584</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0067"><titleInfo><title>Activation of autophagy by alpha‐herpesviruses in myeloid cells is mediated by cytoplasmic viral DNA through a mechanism dependent on stimulator of IFN genes</title></titleInfo><name type="personal"><namePart type="given">SB</namePart><namePart type="family">Rasmussen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">KA</namePart><namePart type="family">Horan</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">CK</namePart><namePart type="family">Holm</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">AJ</namePart><namePart type="family">Stranks</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">TC</namePart><namePart type="family">Mettenleiter</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">AK</namePart><namePart type="family">Simon</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SB</namePart><namePart type="family">Jensen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">FJ</namePart><namePart type="family">Rixon</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">He</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SR</namePart><namePart type="family">Paludan</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Rasmussen SB, Horan KA, Holm CK, Stranks AJ, Mettenleiter TC, Simon AK, Jensen SB, Rixon FJ, He B, Paludan SR. Activation of autophagy by alpha‐herpesviruses in myeloid cells is mediated by cytoplasmic viral DNA through a mechanism dependent on stimulator of IFN genes. J Immunol 2011;187:5268–5276.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>187</number></detail><extent unit="pages"><start>5268</start><end>5276</end></extent></part><relatedItem type="host"><titleInfo><title>J Immunol</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>187</number></detail><extent unit="pages"><start>5268</start><end>5276</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0068"><titleInfo><title>Autophagy is an essential component of Drosophila immunity against vesicular stomatitis virus</title></titleInfo><name type="personal"><namePart type="given">S</namePart><namePart type="family">Shelly</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">N</namePart><namePart type="family">Lukinova</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Bambina</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Berman</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Cherry</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Shelly S, Lukinova N, Bambina S, Berman A, Cherry S. Autophagy is an essential component of Drosophila immunity against vesicular stomatitis virus. Immunity 2009;30:588–598.</note><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>30</number></detail><extent unit="pages"><start>588</start><end>598</end></extent></part><relatedItem type="host"><titleInfo><title>Immunity</title></titleInfo><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>30</number></detail><extent unit="pages"><start>588</start><end>598</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0069"><titleInfo><title>HIV‐1 gp41 fusogenic function triggers autophagy in uninfected cells</title></titleInfo><name type="personal"><namePart type="given">M</namePart><namePart type="family">Denizot</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Varbanov</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Espert</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">V</namePart><namePart type="family">Robert‐Hebmann</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Sagnier</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E</namePart><namePart type="family">Garcia</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Curriu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Mamoun</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Blanco</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Biard‐Piechaczyk</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Denizot M, Varbanov M, Espert L, Robert‐Hebmann V, Sagnier S, Garcia E, Curriu M, Mamoun R, Blanco J, Biard‐Piechaczyk M. HIV‐1 gp41 fusogenic function triggers autophagy in uninfected cells. Autophagy 2008;4:998–1008.</note><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>4</number></detail><extent unit="pages"><start>998</start><end>1008</end></extent></part><relatedItem type="host"><titleInfo><title>Autophagy</title></titleInfo><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>4</number></detail><extent unit="pages"><start>998</start><end>1008</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0070"><titleInfo><title>Autophagy is involved in T cell death after binding of HIV‐1 envelope proteins to CXCR4</title></titleInfo><name type="personal"><namePart type="given">L</namePart><namePart type="family">Espert</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Denizot</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Grimaldi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">V</namePart><namePart type="family">Robert‐Hebmann</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Gay</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Varbanov</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Codogno</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Biard‐Piechaczyk</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Espert L, Denizot M, Grimaldi M, Robert‐Hebmann V, Gay B, Varbanov M, Codogno P, Biard‐Piechaczyk M. Autophagy is involved in T cell death after binding of HIV‐1 envelope proteins to CXCR4. J Clin Invest 2006;116:2161–2172.</note><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>116</number></detail><extent unit="pages"><start>2161</start><end>2172</end></extent></part><relatedItem type="host"><titleInfo><title>J Clin Invest</title></titleInfo><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>116</number></detail><extent unit="pages"><start>2161</start><end>2172</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0071"><titleInfo><title>Production of interferon alpha by human immunodeficiency virus type 1 in human plasmacytoid dendritic cells is dependent on induction of autophagy</title></titleInfo><name type="personal"><namePart type="given">D</namePart><namePart type="family">Zhou</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">KH</namePart><namePart type="family">Kang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SA</namePart><namePart type="family">Spector</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Zhou D, Kang KH, Spector SA. Production of interferon alpha by human immunodeficiency virus type 1 in human plasmacytoid dendritic cells is dependent on induction of autophagy. J Infect Dis 2012;205:1258–1267.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>205</number></detail><extent unit="pages"><start>1258</start><end>1267</end></extent></part><relatedItem type="host"><titleInfo><title>J Infect Dis</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>205</number></detail><extent unit="pages"><start>1258</start><end>1267</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0072"><titleInfo><title>Virus recognition by Toll‐7 activates antiviral autophagy in Drosophila</title></titleInfo><name type="personal"><namePart type="given">M</namePart><namePart type="family">Nakamoto</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">RH</namePart><namePart type="family">Moy</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Xu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Bambina</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Yasunaga</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SS</namePart><namePart type="family">Shelly</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Gold</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Cherry</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Nakamoto M, Moy RH, Xu J, Bambina S, Yasunaga A, Shelly SS, Gold B, Cherry S. Virus recognition by Toll‐7 activates antiviral autophagy in Drosophila. Immunity 2012;36:658–667.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>36</number></detail><extent unit="pages"><start>658</start><end>667</end></extent></part><relatedItem type="host"><titleInfo><title>Immunity</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>36</number></detail><extent unit="pages"><start>658</start><end>667</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0073"><titleInfo><title>IRGM is a common target of RNA viruses that subvert the autophagy network</title></titleInfo><name type="personal"><namePart type="given">IP</namePart><namePart type="family">Gregoire</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Richetta</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Meyniel‐Schicklin</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Borel</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F</namePart><namePart type="family">Pradezynski</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">O</namePart><namePart type="family">Diaz</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Deloire</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">O</namePart><namePart type="family">Azocar</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Baguet</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Le Breton</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">PE</namePart><namePart type="family">Mangeot</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">V</namePart><namePart type="family">Navratil</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">PE</namePart><namePart type="family">Joubert</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Flacher</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">PO</namePart><namePart type="family">Vidalain</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">André</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">V</namePart><namePart type="family">Lotteau</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Biard‐Piechaczyk</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Rabourdin‐Combe</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Faure</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Gregoire IP, Richetta C, Meyniel‐Schicklin L, Borel S, Pradezynski F, Diaz O, Deloire A, Azocar O, Baguet J, Le Breton M, Mangeot PE, Navratil V, Joubert PE, Flacher M, Vidalain PO, André P, Lotteau V, Biard‐Piechaczyk M, Rabourdin‐Combe C, Faure M. IRGM is a common target of RNA viruses that subvert the autophagy network. PLoS Pathog 2011;7:e1002422.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>7</number></detail><extent unit="pages"><start>e1002422</start></extent></part><relatedItem type="host"><titleInfo><title>PLoS Pathog</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>7</number></detail><extent unit="pages"><start>e1002422</start></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0074"><titleInfo><title>Matrix protein 2 of influenza A virus blocks autophagosome fusion with lysosomes</title></titleInfo><name type="personal"><namePart type="given">M</namePart><namePart type="family">Gannage</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">Dormann</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Albrecht</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Dengjel</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Torossi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">PC</namePart><namePart type="family">Ramer</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Lee</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Strowig</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F</namePart><namePart type="family">Arrey</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Conenello</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Pypaert</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Andersen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Garcia‐Sastre</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Munz</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Gannage M, Dormann D, Albrecht R, Dengjel J, Torossi T, Ramer PC, Lee M, Strowig T, Arrey F, Conenello G, Pypaert M, Andersen J, Garcia‐Sastre A, Munz C. Matrix protein 2 of influenza A virus blocks autophagosome fusion with lysosomes. Cell Host Microbe 2009;6:367–380.</note><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>6</number></detail><extent unit="pages"><start>367</start><end>380</end></extent></part><relatedItem type="host"><titleInfo><title>Cell Host Microbe</title></titleInfo><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>6</number></detail><extent unit="pages"><start>367</start><end>380</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0075"><titleInfo><title>Structural and biochemical bases for the inhibition of autophagy and apoptosis by viral BCL‐2 of murine gamma‐herpesvirus 68</title></titleInfo><name type="personal"><namePart type="given">B</namePart><namePart type="family">Ku</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JS</namePart><namePart type="family">Woo</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Liang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">KH</namePart><namePart type="family">Lee</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">HS</namePart><namePart type="family">Hong</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">X</namePart><namePart type="family">E</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">KS</namePart><namePart type="family">Kim</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JU</namePart><namePart type="family">Jung</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">BH</namePart><namePart type="family">Oh</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Ku B, Woo JS, Liang C, Lee KH, Hong HS, E X, Kim KS, Jung JU, Oh BH. Structural and biochemical bases for the inhibition of autophagy and apoptosis by viral BCL‐2 of murine gamma‐herpesvirus 68. PLoS Pathog 2008;4:e25.</note><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>4</number></detail><extent unit="pages"><start>e25</start></extent></part><relatedItem type="host"><titleInfo><title>PLoS Pathog</title></titleInfo><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>4</number></detail><extent unit="pages"><start>e25</start></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0076"><titleInfo><title>HSV‐1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein</title></titleInfo><name type="personal"><namePart type="given">A</namePart><namePart type="family">Orvedahl</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">Alexander</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Z</namePart><namePart type="family">Talloczy</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Q</namePart><namePart type="family">Sun</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Wei</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">W</namePart><namePart type="family">Zhang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">Burns</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">DA</namePart><namePart type="family">Leib</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Levine</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Orvedahl A, Alexander D, Talloczy Z, Sun Q, Wei Y, Zhang W, Burns D, Leib DA, Levine B. HSV‐1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein. Cell Host Microbe 2007;1:23–35.</note><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>1</number></detail><extent unit="pages"><start>23</start><end>35</end></extent></part><relatedItem type="host"><titleInfo><title>Cell Host Microbe</title></titleInfo><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>1</number></detail><extent unit="pages"><start>23</start><end>35</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0077"><titleInfo><title>Molecular basis of the regulation of Beclin 1‐dependent autophagy by the gamma‐herpesvirus 68 Bcl‐2 homolog M11</title></titleInfo><name type="personal"><namePart type="given">S</namePart><namePart type="family">Sinha</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">CL</namePart><namePart type="family">Colbert</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">N</namePart><namePart type="family">Becker</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Wei</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Levine</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Sinha S, Colbert CL, Becker N, Wei Y, Levine B. Molecular basis of the regulation of Beclin 1‐dependent autophagy by the gamma‐herpesvirus 68 Bcl‐2 homolog M11. Autophagy 2008;4:989–997.</note><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>4</number></detail><extent unit="pages"><start>989</start><end>997</end></extent></part><relatedItem type="host"><titleInfo><title>Autophagy</title></titleInfo><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>4</number></detail><extent unit="pages"><start>989</start><end>997</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0078"><titleInfo><title>Bcl‐2 antiapoptotic proteins inhibit Beclin 1‐dependent autophagy</title></titleInfo><name type="personal"><namePart type="given">S</namePart><namePart type="family">Pattingre</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Tassa</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">X</namePart><namePart type="family">Qu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Garuti</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">XH</namePart><namePart type="family">Liang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">N</namePart><namePart type="family">Mizushima</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Packer</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MD</namePart><namePart type="family">Schneider</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Levine</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Pattingre S, Tassa A, Qu X, Garuti R, Liang XH, Mizushima N, Packer M, Schneider MD, Levine B. Bcl‐2 antiapoptotic proteins inhibit Beclin 1‐dependent autophagy. Cell 2005;122:927–939.</note><part><date>2005</date><detail type="volume"><caption>vol.</caption><number>122</number></detail><extent unit="pages"><start>927</start><end>939</end></extent></part><relatedItem type="host"><titleInfo><title>Cell</title></titleInfo><part><date>2005</date><detail type="volume"><caption>vol.</caption><number>122</number></detail><extent unit="pages"><start>927</start><end>939</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0079"><titleInfo><title>The herpes simplex virus 1 Us11 protein inhibits autophagy through its interaction with the protein kinase PKR</title></titleInfo><name type="personal"><namePart type="given">M</namePart><namePart type="family">Lussignol</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Queval</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MF</namePart><namePart type="family">Bernet‐Camard</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Cotte‐Laffitte</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">I</namePart><namePart type="family">Beau</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Codogno</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Esclatine</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Lussignol M, Queval C, Bernet‐Camard MF, Cotte‐Laffitte J, Beau I, Codogno P, Esclatine A. The herpes simplex virus 1 Us11 protein inhibits autophagy through its interaction with the protein kinase PKR. J Virol 2013;87:859–871.</note><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>87</number></detail><extent unit="pages"><start>859</start><end>871</end></extent></part><relatedItem type="host"><titleInfo><title>J Virol</title></titleInfo><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>87</number></detail><extent unit="pages"><start>859</start><end>871</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0080"><titleInfo><title>FLIP‐mediated autophagy regulation in cell death control</title></titleInfo><name type="personal"><namePart type="given">JS</namePart><namePart type="family">Lee</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Q</namePart><namePart type="family">Li</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JY</namePart><namePart type="family">Lee</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SH</namePart><namePart type="family">Lee</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JH</namePart><namePart type="family">Jeong</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">HR</namePart><namePart type="family">Lee</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">H</namePart><namePart type="family">Chang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">FC</namePart><namePart type="family">Zhou</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SJ</namePart><namePart type="family">Gao</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Liang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JU</namePart><namePart type="family">Jung</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Lee JS, Li Q, Lee JY, Lee SH, Jeong JH, Lee HR, Chang H, Zhou FC, Gao SJ, Liang C, Jung JU. FLIP‐mediated autophagy regulation in cell death control. Nat Cell Biol 2009;11:1355–1362.</note><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>11</number></detail><extent unit="pages"><start>1355</start><end>1362</end></extent></part><relatedItem type="host"><titleInfo><title>Nat Cell Biol</title></titleInfo><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>11</number></detail><extent unit="pages"><start>1355</start><end>1362</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0081"><titleInfo><title>Cellular entry of human papillomavirus type 16 involves activation of the phosphatidylinositol 3‐kinase/Akt/mTOR pathway and inhibition of autophagy</title></titleInfo><name type="personal"><namePart type="given">Z</namePart><namePart type="family">Surviladze</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">RT</namePart><namePart type="family">Sterk</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SA</namePart><namePart type="family">DeHaro</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MA</namePart><namePart type="family">Ozbun</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Surviladze Z, Sterk RT, DeHaro SA, Ozbun MA. Cellular entry of human papillomavirus type 16 involves activation of the phosphatidylinositol 3‐kinase/Akt/mTOR pathway and inhibition of autophagy. J Virol 2013;87:2508–2517.</note><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>87</number></detail><extent unit="pages"><start>2508</start><end>2517</end></extent></part><relatedItem type="host"><titleInfo><title>J Virol</title></titleInfo><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>87</number></detail><extent unit="pages"><start>2508</start><end>2517</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0082"><titleInfo><title>Human cytomegalovirus controls a new autophagy‐dependent cellular antiviral defense mechanism</title></titleInfo><name type="personal"><namePart type="given">M</namePart><namePart type="family">Chaumorcel</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Souquere</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Pierron</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Codogno</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Esclatine</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Chaumorcel M, Souquere S, Pierron G, Codogno P, Esclatine A. Human cytomegalovirus controls a new autophagy‐dependent cellular antiviral defense mechanism. Autophagy 2008;4:46–53.</note><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>4</number></detail><extent unit="pages"><start>46</start><end>53</end></extent></part><relatedItem type="host"><titleInfo><title>Autophagy</title></titleInfo><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>4</number></detail><extent unit="pages"><start>46</start><end>53</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0083"><titleInfo><title>Disruption of neuronal autophagy by infected microglia results in neurodegeneration</title></titleInfo><name type="personal"><namePart type="given">M</namePart><namePart type="family">Alirezaei</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">WB</namePart><namePart type="family">Kiosses</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">CT</namePart><namePart type="family">Flynn</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">NR</namePart><namePart type="family">Brady</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">HS</namePart><namePart type="family">Fox</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Alirezaei M, Kiosses WB, Flynn CT, Brady NR, Fox HS. Disruption of neuronal autophagy by infected microglia results in neurodegeneration. PLoS One 2008;3:e2906.</note><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>3</number></detail><extent unit="pages"><start>e2906</start></extent></part><relatedItem type="host"><titleInfo><title>PLoS One</title></titleInfo><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>3</number></detail><extent unit="pages"><start>e2906</start></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0084"><titleInfo><title>Autophagy hijacked through viroporin‐activated calcium/calmodulin‐dependent kinase kinase‐beta signaling is required for rotavirus replication</title></titleInfo><name type="personal"><namePart type="given">SE</namePart><namePart type="family">Crawford</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JM</namePart><namePart type="family">Hyser</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Utama</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MK</namePart><namePart type="family">Estes</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Crawford SE, Hyser JM, Utama B, Estes MK. Autophagy hijacked through viroporin‐activated calcium/calmodulin‐dependent kinase kinase‐beta signaling is required for rotavirus replication. Proc Natl Acad Sci USA 2012;109:E3405–E3413.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>109</number></detail><extent unit="pages"><start>E3405</start><end>E3413</end></extent></part><relatedItem type="host"><titleInfo><title>Proc Natl Acad Sci USA</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>109</number></detail><extent unit="pages"><start>E3405</start><end>E3413</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0085"><titleInfo><title>Human immunodeficiency virus type‐1 infection inhibits autophagy</title></titleInfo><name type="personal"><namePart type="given">D</namePart><namePart type="family">Zhou</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SA</namePart><namePart type="family">Spector</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Zhou D, Spector SA. Human immunodeficiency virus type‐1 infection inhibits autophagy. Aids 2008;22:695–699.</note><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>22</number></detail><extent unit="pages"><start>695</start><end>699</end></extent></part><relatedItem type="host"><titleInfo><title>Aids</title></titleInfo><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>22</number></detail><extent unit="pages"><start>695</start><end>699</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0086"><titleInfo><title>Dual role of 3‐methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3‐kinase</title></titleInfo><name type="personal"><namePart type="given">YT</namePart><namePart type="family">Wu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">HL</namePart><namePart type="family">Tan</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Shui</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Bauvy</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Q</namePart><namePart type="family">Huang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MR</namePart><namePart type="family">Wenk</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">CN</namePart><namePart type="family">Ong</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Codogno</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">HM</namePart><namePart type="family">Shen</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Wu YT, Tan HL, Shui G, Bauvy C, Huang Q, Wenk MR, Ong CN, Codogno P, Shen HM. Dual role of 3‐methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3‐kinase. J Biol Chem 2010;285:10850–10861.</note><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>285</number></detail><extent unit="pages"><start>10850</start><end>10861</end></extent></part><relatedItem type="host"><titleInfo><title>J Biol Chem</title></titleInfo><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>285</number></detail><extent unit="pages"><start>10850</start><end>10861</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0087"><titleInfo><title>Chloroquine‐mediated lysosomal dysfunction enhances the anticancer effect of nutrient deprivation</title></titleInfo><name type="personal"><namePart type="given">L</namePart><namePart type="family">Harhaji‐Trajkovic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Arsikin</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Kravic‐Stevovic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Petricevic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Tovilovic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Pantovic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">N</namePart><namePart type="family">Zogovic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Ristic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Janjetovic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">V</namePart><namePart type="family">Bumbasirevic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">V</namePart><namePart type="family">Trajkovic</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Harhaji‐Trajkovic L, Arsikin K, Kravic‐Stevovic T, Petricevic S, Tovilovic G, Pantovic A, Zogovic N, Ristic B, Janjetovic K, Bumbasirevic V, Trajkovic V. Chloroquine‐mediated lysosomal dysfunction enhances the anticancer effect of nutrient deprivation. Pharm Res 2012;29:2249–2263.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>29</number></detail><extent unit="pages"><start>2249</start><end>2263</end></extent></part><relatedItem type="host"><titleInfo><title>Pharm Res</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>29</number></detail><extent unit="pages"><start>2249</start><end>2263</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0088"><titleInfo><title>Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy</title></titleInfo><name type="personal"><namePart type="given">P</namePart><namePart type="family">Maycotte</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Aryal</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">CT</namePart><namePart type="family">Cummings</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Thorburn</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MJ</namePart><namePart type="family">Morgan</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Thorburn</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Maycotte P, Aryal S, Cummings CT, Thorburn J, Morgan MJ, Thorburn A. Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy. Autophagy 2012;8:200–212.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>8</number></detail><extent unit="pages"><start>200</start><end>212</end></extent></part><relatedItem type="host"><titleInfo><title>Autophagy</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>8</number></detail><extent unit="pages"><start>200</start><end>212</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0089"><titleInfo><title>Receptor‐mediated entry by equine infectious anemia virus utilizes a pH‐dependent endocytic pathway</title></titleInfo><name type="personal"><namePart type="given">S</namePart><namePart type="family">Jin</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Zhang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">OA</namePart><namePart type="family">Weisz</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">RC</namePart><namePart type="family">Montelaro</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Jin S, Zhang B, Weisz OA, Montelaro RC. Receptor‐mediated entry by equine infectious anemia virus utilizes a pH‐dependent endocytic pathway. J Virol 2005;79:14489–14497.</note><part><date>2005</date><detail type="volume"><caption>vol.</caption><number>79</number></detail><extent unit="pages"><start>14489</start><end>14497</end></extent></part><relatedItem type="host"><titleInfo><title>J Virol</title></titleInfo><part><date>2005</date><detail type="volume"><caption>vol.</caption><number>79</number></detail><extent unit="pages"><start>14489</start><end>14497</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0090"><titleInfo><title>Porcine reproductive and respiratory syndrome virus enters cells through a low pH‐dependent endocytic pathway</title></titleInfo><name type="personal"><namePart type="given">LC</namePart><namePart type="family">Kreutz</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MR</namePart><namePart type="family">Ackermann</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Kreutz LC, Ackermann MR. Porcine reproductive and respiratory syndrome virus enters cells through a low pH‐dependent endocytic pathway. Virus Res 1996;42:137–147.</note><part><date>1996</date><detail type="volume"><caption>vol.</caption><number>42</number></detail><extent unit="pages"><start>137</start><end>147</end></extent></part><relatedItem type="host"><titleInfo><title>Virus Res</title></titleInfo><part><date>1996</date><detail type="volume"><caption>vol.</caption><number>42</number></detail><extent unit="pages"><start>137</start><end>147</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0091"><titleInfo><title>Entry of bovine viral diarrhea virus into ovine cells occurs through clathrin‐dependent endocytosis and low pH‐dependent fusion</title></titleInfo><name type="personal"><namePart type="given">BS</namePart><namePart type="family">Mathapati</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">N</namePart><namePart type="family">Mishra</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Rajukumar</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">RK</namePart><namePart type="family">Nema</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SP</namePart><namePart type="family">Behera</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SC</namePart><namePart type="family">Dubey</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Mathapati BS, Mishra N, Rajukumar K, Nema RK, Behera SP, Dubey SC. Entry of bovine viral diarrhea virus into ovine cells occurs through clathrin‐dependent endocytosis and low pH‐dependent fusion. In Vitro Cell Dev Biol Anim 2010;46:403–407.</note><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>46</number></detail><extent unit="pages"><start>403</start><end>407</end></extent></part><relatedItem type="host"><titleInfo><title>In Vitro Cell Dev Biol Anim</title></titleInfo><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>46</number></detail><extent unit="pages"><start>403</start><end>407</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0092"><titleInfo><title>Knockdown of autophagy enhances the innate immune response in hepatitis C virus‐infected hepatocytes</title></titleInfo><name type="personal"><namePart type="given">S</namePart><namePart type="family">Shrivastava</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Raychoudhuri</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Steele</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Ray</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">RB</namePart><namePart type="family">Ray</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Shrivastava S, Raychoudhuri A, Steele R, Ray R, Ray RB. Knockdown of autophagy enhances the innate immune response in hepatitis C virus‐infected hepatocytes. Hepatology 2011;53:406–414.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>53</number></detail><extent unit="pages"><start>406</start><end>414</end></extent></part><relatedItem type="host"><titleInfo><title>Hepatology</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>53</number></detail><extent unit="pages"><start>406</start><end>414</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0093"><titleInfo><title>Dysfunction of autophagy participates in vacuole formation and cell death in cells replicating hepatitis C virus</title></titleInfo><name type="personal"><namePart type="given">S</namePart><namePart type="family">Taguwa</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">H</namePart><namePart type="family">Kambara</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">N</namePart><namePart type="family">Fujita</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Noda</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Yoshimori</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Koike</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Moriishi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Matsuura</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Taguwa S, Kambara H, Fujita N, Noda T, Yoshimori T, Koike K, Moriishi K, Matsuura Y. Dysfunction of autophagy participates in vacuole formation and cell death in cells replicating hepatitis C virus. J Virol 2011;85:13185–13194.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>85</number></detail><extent unit="pages"><start>13185</start><end>13194</end></extent></part><relatedItem type="host"><titleInfo><title>J Virol</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>85</number></detail><extent unit="pages"><start>13185</start><end>13194</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0094"><titleInfo><title>Japanese encephalitis virus activates autophagy as a viral immune evasion strategy</title></titleInfo><name type="personal"><namePart type="given">R</namePart><namePart type="family">Jin</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">W</namePart><namePart type="family">Zhu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Cao</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Chen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">H</namePart><namePart type="family">Jin</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Liu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Wang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">W</namePart><namePart type="family">Wang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Xiao</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Jin R, Zhu W, Cao S, Chen R, Jin H, Liu Y, Wang S, Wang W, Xiao G. Japanese encephalitis virus activates autophagy as a viral immune evasion strategy. PLoS One 2013;8:e52909.</note><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>8</number></detail><extent unit="pages"><start>e52909</start></extent></part><relatedItem type="host"><titleInfo><title>PLoS One</title></titleInfo><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>8</number></detail><extent unit="pages"><start>e52909</start></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0095"><titleInfo><title>Gammaherpesvirus 68 infection of endothelial cells requires both host autophagy genes and viral oncogenes for optimal survival and persistence</title></titleInfo><name type="personal"><namePart type="given">AL</namePart><namePart type="family">Suarez</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Kong</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">George</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">He</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Z</namePart><namePart type="family">Yue</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">LF</namePart><namePart type="family">van Dyk</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Suarez AL, Kong R, George T, He L, Yue Z, van Dyk LF. Gammaherpesvirus 68 infection of endothelial cells requires both host autophagy genes and viral oncogenes for optimal survival and persistence. J Virol 2011;85:6293–6308.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>85</number></detail><extent unit="pages"><start>6293</start><end>6308</end></extent></part><relatedItem type="host"><titleInfo><title>J Virol</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>85</number></detail><extent unit="pages"><start>6293</start><end>6308</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0098"><titleInfo><title>Autophagy regulates programmed cell death during the plant innate immune response</title></titleInfo><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Liu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Schiff</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Czymmek</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Z</namePart><namePart type="family">Talloczy</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Levine</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SP</namePart><namePart type="family">Dinesh‐Kumar</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Liu Y, Schiff M, Czymmek K, Talloczy Z, Levine B, Dinesh‐Kumar SP. Autophagy regulates programmed cell death during the plant innate immune response. Cell 2005;121:567–577.</note><part><date>2005</date><detail type="volume"><caption>vol.</caption><number>121</number></detail><extent unit="pages"><start>567</start><end>577</end></extent></part><relatedItem type="host"><titleInfo><title>Cell</title></titleInfo><part><date>2005</date><detail type="volume"><caption>vol.</caption><number>121</number></detail><extent unit="pages"><start>567</start><end>577</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0099"><titleInfo><title>Herpes simplex virus type 1 and Alzheimer's disease: The autophagy connection</title></titleInfo><name type="personal"><namePart type="given">RF</namePart><namePart type="family">Itzhaki</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SL</namePart><namePart type="family">Cosby</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MA</namePart><namePart type="family">Wozniak</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Itzhaki RF, Cosby SL, Wozniak MA. Herpes simplex virus type 1 and Alzheimer's disease: The autophagy connection. J Neurovirol 2008;14:1–4.</note><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>14</number></detail><extent unit="pages"><start>1</start><end>4</end></extent></part><relatedItem type="host"><titleInfo><title>J Neurovirol</title></titleInfo><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>14</number></detail><extent unit="pages"><start>1</start><end>4</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0100"><titleInfo><title>Herpes simplex virus type I induces the accumulation of intracellular beta‐amyloid in autophagic compartments and the inhibition of the non‐amyloidogenic pathway in human neuroblastoma cells</title></titleInfo><name type="personal"><namePart type="given">S</namePart><namePart type="family">Santana</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Recuero</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MJ</namePart><namePart type="family">Bullido</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F</namePart><namePart type="family">Valdivieso</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Aldudo</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Santana S, Recuero M, Bullido MJ, Valdivieso F, Aldudo J. Herpes simplex virus type I induces the accumulation of intracellular beta‐amyloid in autophagic compartments and the inhibition of the non‐amyloidogenic pathway in human neuroblastoma cells. Neurobiol Aging 2012;33:430.e19–430.e33.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>33</number></detail><extent unit="pages"><start>430.e19</start><end>430.e33</end></extent></part><relatedItem type="host"><titleInfo><title>Neurobiol Aging</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>33</number></detail><extent unit="pages"><start>430.e19</start><end>430.e33</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0101"><titleInfo><title>Mechanisms of apoptosis regulation by viral oncogenes in infection and tumorigenesis</title></titleInfo><name type="personal"><namePart type="given">E</namePart><namePart type="family">White</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">White E. Mechanisms of apoptosis regulation by viral oncogenes in infection and tumorigenesis. Cell Death Differ 2006;13:1371–1377.</note><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>13</number></detail><extent unit="pages"><start>1371</start><end>1377</end></extent></part><relatedItem type="host"><titleInfo><title>Cell Death Differ</title></titleInfo><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>13</number></detail><extent unit="pages"><start>1371</start><end>1377</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0096"><titleInfo><title>Hepatitis B virus X protein reduces starvation‐induced cell death through activation of autophagy and inhibition of mitochondrial apoptotic pathway</title></titleInfo><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Mao</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Da</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">H</namePart><namePart type="family">Tang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Yang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Lei</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Tiollais</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Li</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Zhao</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Mao Y, Da L, Tang H, Yang J, Lei Y, Tiollais P, Li T, Zhao M. Hepatitis B virus X protein reduces starvation‐induced cell death through activation of autophagy and inhibition of mitochondrial apoptotic pathway. Biochem Biophys Res Commun 2011;415:68–74.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>415</number></detail><extent unit="pages"><start>68</start><end>74</end></extent></part><relatedItem type="host"><titleInfo><title>Biochem Biophys Res Commun</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>415</number></detail><extent unit="pages"><start>68</start><end>74</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0097"><titleInfo><title>Viral FLICE inhibitory protein of rhesus monkey rhadinovirus inhibits apoptosis by enhancing autophagosome formation</title></titleInfo><name type="personal"><namePart type="given">K</namePart><namePart type="family">Ritthipichai</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Nan</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">I</namePart><namePart type="family">Bossis</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Zhang</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Ritthipichai K, Nan Y, Bossis I, Zhang Y. Viral FLICE inhibitory protein of rhesus monkey rhadinovirus inhibits apoptosis by enhancing autophagosome formation. PLoS One 2012;7:e39438.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>7</number></detail><extent unit="pages"><start>e39438</start></extent></part><relatedItem type="host"><titleInfo><title>PLoS One</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>7</number></detail><extent unit="pages"><start>e39438</start></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0102"><titleInfo><title>The evolution of virus‐induced apoptosis</title></titleInfo><name type="personal"><namePart type="given">DC</namePart><namePart type="family">Krakauer</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">RJ</namePart><namePart type="family">Payne</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Krakauer DC, Payne RJ. The evolution of virus‐induced apoptosis. Proc Biol Sci 1997;264:1757–1762.</note><part><date>1997</date><detail type="volume"><caption>vol.</caption><number>264</number></detail><extent unit="pages"><start>1757</start><end>1762</end></extent></part><relatedItem type="host"><titleInfo><title>Proc Biol Sci</title></titleInfo><part><date>1997</date><detail type="volume"><caption>vol.</caption><number>264</number></detail><extent unit="pages"><start>1757</start><end>1762</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0103"><titleInfo><title>Chikungunya virus mobilizes the apoptotic machinery to invade host cell defenses</title></titleInfo><name type="personal"><namePart type="given">P</namePart><namePart type="family">Krejbich‐Trotot</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Denizot</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JJ</namePart><namePart type="family">Hoarau</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MC</namePart><namePart type="family">Jaffar‐Bandjee</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Das</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Gasque</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Krejbich‐Trotot P, Denizot M, Hoarau JJ, Jaffar‐Bandjee MC, Das T, Gasque P. Chikungunya virus mobilizes the apoptotic machinery to invade host cell defenses. Faseb J 2011;25:314–325.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>25</number></detail><extent unit="pages"><start>314</start><end>325</end></extent></part><relatedItem type="host"><titleInfo><title>Faseb J</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>25</number></detail><extent unit="pages"><start>314</start><end>325</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0104"><titleInfo><title>The interplays between autophagy and apoptosis induced by enterovirus 71</title></titleInfo><name type="personal"><namePart type="given">X</namePart><namePart type="family">Xi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">X</namePart><namePart type="family">Zhang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Wang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Wang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Wang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">H</namePart><namePart type="family">Huang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Wang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Q</namePart><namePart type="family">Jin</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Z</namePart><namePart type="family">Zhao</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Xi X, Zhang X, Wang B, Wang T, Wang J, Huang H, Wang J, Jin Q, Zhao Z. The interplays between autophagy and apoptosis induced by enterovirus 71. PLoS One 2013;8:e56966.</note><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>8</number></detail><extent unit="pages"><start>e56966</start></extent></part><relatedItem type="host"><titleInfo><title>PLoS One</title></titleInfo><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>8</number></detail><extent unit="pages"><start>e56966</start></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0105"><titleInfo><title>The crosstalk between autophagy and apoptosis: Where does this lead?</title></titleInfo><name type="personal"><namePart type="given">C</namePart><namePart type="family">Gordy</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">YW</namePart><namePart type="family">He</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Gordy C, He YW. The crosstalk between autophagy and apoptosis: Where does this lead? Protein Cell 2012;3:17–27.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>3</number></detail><extent unit="pages"><start>17</start><end>27</end></extent></part><relatedItem type="host"><titleInfo><title>Protein Cell</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>3</number></detail><extent unit="pages"><start>17</start><end>27</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0106"><titleInfo><title>Autophagy suppresses RIP kinase‐dependent necrosis enabling survival to mTOR inhibition</title></titleInfo><name type="personal"><namePart type="given">K</namePart><namePart type="family">Bray</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Mathew</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Lau</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JJ</namePart><namePart type="family">Kamphorst</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Fan</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Chen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">HY</namePart><namePart type="family">Chen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Ghavami</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Stein</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">RS</namePart><namePart type="family">DiPaola</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">Zhang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JD</namePart><namePart type="family">Rabinowitz</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E</namePart><namePart type="family">White</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Bray K, Mathew R, Lau A, Kamphorst JJ, Fan J, Chen J, Chen HY, Ghavami A, Stein M, DiPaola RS, Zhang D, Rabinowitz JD, White E. Autophagy suppresses RIP kinase‐dependent necrosis enabling survival to mTOR inhibition. PLoS One 2012;7:e41831.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>7</number></detail><extent unit="pages"><start>e41831</start></extent></part><relatedItem type="host"><titleInfo><title>PLoS One</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>7</number></detail><extent unit="pages"><start>e41831</start></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0107"><titleInfo><title>Receptor interacting protein kinase 2‐mediated mitophagy regulates inflammasome activation during virus infection</title></titleInfo><name type="personal"><namePart type="given">C</namePart><namePart type="family">Lupfer</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">PG</namePart><namePart type="family">Thomas</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">PK</namePart><namePart type="family">Anand</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Vogel</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Milasta</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Martinez</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Huang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Green</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Kundu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">H</namePart><namePart type="family">Chi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">RJ</namePart><namePart type="family">Xavier</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">DR</namePart><namePart type="family">Green</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Lamkanfi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">CA</namePart><namePart type="family">Dinarello</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">PC</namePart><namePart type="family">Doherty</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">TD</namePart><namePart type="family">Kanneganti</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Lupfer C, Thomas PG, Anand PK, Vogel P, Milasta S, Martinez J, Huang G, Green M, Kundu M, Chi H, Xavier RJ, Green DR, Lamkanfi M, Dinarello CA, Doherty PC, Kanneganti TD. Receptor interacting protein kinase 2‐mediated mitophagy regulates inflammasome activation during virus infection. Nat Immunol 2013;14:480–488.</note><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>14</number></detail><extent unit="pages"><start>480</start><end>488</end></extent></part><relatedItem type="host"><titleInfo><title>Nat Immunol</title></titleInfo><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>14</number></detail><extent unit="pages"><start>480</start><end>488</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0108"><titleInfo><title>Autophagy in cell death: An innocent convict?</title></titleInfo><name type="personal"><namePart type="given">B</namePart><namePart type="family">Levine</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Yuan</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Levine B, Yuan J. Autophagy in cell death: An innocent convict? J Clin Invest 2005;115:2679–2688.</note><part><date>2005</date><detail type="volume"><caption>vol.</caption><number>115</number></detail><extent unit="pages"><start>2679</start><end>2688</end></extent></part><relatedItem type="host"><titleInfo><title>J Clin Invest</title></titleInfo><part><date>2005</date><detail type="volume"><caption>vol.</caption><number>115</number></detail><extent unit="pages"><start>2679</start><end>2688</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0109"><titleInfo><title>Cell death by autophagy: Facts and apparent artefacts</title></titleInfo><name type="personal"><namePart type="given">D</namePart><namePart type="family">Denton</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Nicolson</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Kumar</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Denton D, Nicolson S, Kumar S. Cell death by autophagy: Facts and apparent artefacts. Cell Death Differ 2012;19:87–95.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>19</number></detail><extent unit="pages"><start>87</start><end>95</end></extent></part><relatedItem type="host"><titleInfo><title>Cell Death Differ</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>19</number></detail><extent unit="pages"><start>87</start><end>95</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0111"><titleInfo><title>Beclin 1 is involved in regulation of apoptosis and autophagy during replication of ectromelia virus in permissive L929 cells</title></titleInfo><name type="personal"><namePart type="given">L</namePart><namePart type="family">Martyniszyn</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Szulc</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Boratynska</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MG</namePart><namePart type="family">Niemialtowski</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Martyniszyn L, Szulc L, Boratynska A, Niemialtowski MG. Beclin 1 is involved in regulation of apoptosis and autophagy during replication of ectromelia virus in permissive L929 cells. Arch Immunol Ther Exp (Warsz) 2011;59:463–471.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>59</number></detail><extent unit="pages"><start>463</start><end>471</end></extent></part><relatedItem type="host"><titleInfo><title>Arch Immunol Ther Exp (Warsz)</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>59</number></detail><extent unit="pages"><start>463</start><end>471</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0112"><titleInfo><title>HIV‐1 and HIV‐2 infections induce autophagy in Jurkat and CD4+ T cells</title></titleInfo><name type="personal"><namePart type="given">X</namePart><namePart type="family">Wang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Gao</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Tan</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Devadas</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">V</namePart><namePart type="family">Ragupathy</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Takeda</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Zhao</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">I</namePart><namePart type="family">Hewlett</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Wang X, Gao Y, Tan J, Devadas K, Ragupathy V, Takeda K, Zhao J, Hewlett I. HIV‐1 and HIV‐2 infections induce autophagy in Jurkat and CD4+ T cells. Cell Signal 2012;24:1414–1419.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>24</number></detail><extent unit="pages"><start>1414</start><end>1419</end></extent></part><relatedItem type="host"><titleInfo><title>Cell Signal</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>24</number></detail><extent unit="pages"><start>1414</start><end>1419</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0114"><titleInfo><title>Human adenovirus type 5 induces cell lysis through autophagy and autophagy‐triggered caspase activity</title></titleInfo><name type="personal"><namePart type="given">H</namePart><namePart type="family">Jiang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">EJ</namePart><namePart type="family">White</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">CI</namePart><namePart type="family">Rios‐Vicil</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Xu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Gomez‐Manzano</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Fueyo</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Jiang H, White EJ, Rios‐Vicil CI, Xu J, Gomez‐Manzano C, Fueyo J. Human adenovirus type 5 induces cell lysis through autophagy and autophagy‐triggered caspase activity. J Virol 2011;85:4720–4729.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>85</number></detail><extent unit="pages"><start>4720</start><end>4729</end></extent></part><relatedItem type="host"><titleInfo><title>J Virol</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>85</number></detail><extent unit="pages"><start>4720</start><end>4729</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0110"><titleInfo><title>Inhibition of autophagy ameliorates acute lung injury caused by avian influenza A H5N1 infection</title></titleInfo><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Sun</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Li</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Shu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">X</namePart><namePart type="family">Ju</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Z</namePart><namePart type="family">Zou</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">H</namePart><namePart type="family">Wang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Rao</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F</namePart><namePart type="family">Guo</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">H</namePart><namePart type="family">Liu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">W</namePart><namePart type="family">Nan</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Zhao</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Yan</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Tang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Zhao</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Yang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Liu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Wang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">H</namePart><namePart type="family">Lu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">X</namePart><namePart type="family">Li</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Tan</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Gao</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Song</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">X</namePart><namePart type="family">Gao</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">X</namePart><namePart type="family">Tian</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Qin</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">KF</namePart><namePart type="family">Xu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">Li</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">N</namePart><namePart type="family">Jin</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Jiang</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Sun Y, Li C, Shu Y, Ju X, Zou Z, Wang H, Rao S, Guo F, Liu H, Nan W, Zhao Y, Yan Y, Tang J, Zhao C, Yang P, Liu K, Wang S, Lu H, Li X, Tan L, Gao R, Song J, Gao X, Tian X, Qin Y, Xu KF, Li D, Jin N, Jiang C. Inhibition of autophagy ameliorates acute lung injury caused by avian influenza A H5N1 infection. Sci Signal 2012;5:ra16.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>5</number></detail><extent unit="pages"><start>ra16</start></extent></part><relatedItem type="host"><titleInfo><title>Sci Signal</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>5</number></detail><extent unit="pages"><start>ra16</start></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0113"><titleInfo><title>Pancreatic acinar cell‐specific autophagy disruption reduces coxsackievirus replication and pathogenesis in vivo</title></titleInfo><name type="personal"><namePart type="given">M</namePart><namePart type="family">Alirezaei</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">CT</namePart><namePart type="family">Flynn</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MR</namePart><namePart type="family">Wood</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JL</namePart><namePart type="family">Whitton</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Alirezaei M, Flynn CT, Wood MR, Whitton JL. Pancreatic acinar cell‐specific autophagy disruption reduces coxsackievirus replication and pathogenesis in vivo. Cell Host Microbe 2012;11:298–305.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>11</number></detail><extent unit="pages"><start>298</start><end>305</end></extent></part><relatedItem type="host"><titleInfo><title>Cell Host Microbe</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>11</number></detail><extent unit="pages"><start>298</start><end>305</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0115"><titleInfo><title>Beclin 1 modulates the anti‐apoptotic activity of Bcl‐2: Insights from a pathogen infection system</title></titleInfo><name type="personal"><namePart type="given">CL</namePart><namePart type="family">Vazquez</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MI</namePart><namePart type="family">Colombo</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Vazquez CL, Colombo MI. Beclin 1 modulates the anti‐apoptotic activity of Bcl‐2: Insights from a pathogen infection system. Autophagy 2010;6:177–178.</note><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>6</number></detail><extent unit="pages"><start>177</start><end>178</end></extent></part><relatedItem type="host"><titleInfo><title>Autophagy</title></titleInfo><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>6</number></detail><extent unit="pages"><start>177</start><end>178</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0116"><titleInfo><title>Atg5: More than an autophagy factor</title></titleInfo><name type="personal"><namePart type="given">P</namePart><namePart type="family">Codogno</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">AJ</namePart><namePart type="family">Meijer</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Codogno P, Meijer AJ. Atg5: More than an autophagy factor. Nat Cell Biol 2006;8:1045–1047.</note><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>8</number></detail><extent unit="pages"><start>1045</start><end>1047</end></extent></part><relatedItem type="host"><titleInfo><title>Nat Cell Biol</title></titleInfo><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>8</number></detail><extent unit="pages"><start>1045</start><end>1047</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0117"><titleInfo><title>Autophagy promotes necrosis in apoptosis‐deficient cells in response to ER stress</title></titleInfo><name type="personal"><namePart type="given">E</namePart><namePart type="family">Ullman</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Fan</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Stawowczyk</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">HM</namePart><namePart type="family">Chen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Z</namePart><namePart type="family">Yue</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">WX</namePart><namePart type="family">Zong</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Ullman E, Fan Y, Stawowczyk M, Chen HM, Yue Z, Zong WX. Autophagy promotes necrosis in apoptosis‐deficient cells in response to ER stress. Cell Death Differ 2008;15:422–425.</note><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>15</number></detail><extent unit="pages"><start>422</start><end>425</end></extent></part><relatedItem type="host"><titleInfo><title>Cell Death Differ</title></titleInfo><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>15</number></detail><extent unit="pages"><start>422</start><end>425</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0118"><titleInfo><title>Enhanced autophagy and reduced expression of cathepsin D are related to autophagic cell death in Epstein–Barr virus‐associated nasal natural killer/T‐cell lymphomas: An immunohistochemical analysis of beclin‐1, LC3, mitochondria (AE‐1), and cathepsin D in nasopharyngeal lymphomas</title></titleInfo><name type="personal"><namePart type="given">K</namePart><namePart type="family">Hasui</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Wang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">X</namePart><namePart type="family">Jia</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Tanaka</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Nagai</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Matsuyama</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Eizuru</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Hasui K, Wang J, Jia X, Tanaka M, Nagai T, Matsuyama T, Eizuru Y. Enhanced autophagy and reduced expression of cathepsin D are related to autophagic cell death in Epstein–Barr virus‐associated nasal natural killer/T‐cell lymphomas: An immunohistochemical analysis of beclin‐1, LC3, mitochondria (AE‐1), and cathepsin D in nasopharyngeal lymphomas. Acta Histochem Cytochem 2011;44:119–131.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>44</number></detail><extent unit="pages"><start>119</start><end>131</end></extent></part><relatedItem type="host"><titleInfo><title>Acta Histochem Cytochem</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>44</number></detail><extent unit="pages"><start>119</start><end>131</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0119"><titleInfo><title>Changes in autophagic response in patients with chronic hepatitis C virus infection</title></titleInfo><name type="personal"><namePart type="given">PE</namePart><namePart type="family">Rautou</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">Cazals‐Hatem</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Feldmann</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Mansouri</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Grodet</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Barge</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Martinot‐Peignoux</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Duces</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">I</namePart><namePart type="family">Bieche</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">Lebrec</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Bedossa</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">V</namePart><namePart type="family">Paradis</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Marcellin</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">Valla</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Asselah</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Moreau</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Rautou PE, Cazals‐Hatem D, Feldmann G, Mansouri A, Grodet A, Barge S, Martinot‐Peignoux M, Duces A, Bieche I, Lebrec D, Bedossa P, Paradis V, Marcellin P, Valla D, Asselah T, Moreau R. Changes in autophagic response in patients with chronic hepatitis C virus infection. Am J Pathol 2011;178:2708–2715.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>178</number></detail><extent unit="pages"><start>2708</start><end>2715</end></extent></part><relatedItem type="host"><titleInfo><title>Am J Pathol</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>178</number></detail><extent unit="pages"><start>2708</start><end>2715</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0120"><titleInfo><title>Autophagy protects cells from HCV‐induced defects in lipid metabolism</title></titleInfo><name type="personal"><namePart type="given">T</namePart><namePart type="family">Vescovo</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Romagnoli</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">AB</namePart><namePart type="family">Perdomo</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Corazzari</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F</namePart><namePart type="family">Ciccosanti</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Alonzi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Nardacci</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Ippolito</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Tripodi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Garcia‐Monzon</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">O</namePart><namePart type="family">Lo Iacono</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Piacentini</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">GM</namePart><namePart type="family">Fimia</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Vescovo T, Romagnoli A, Perdomo AB, Corazzari M, Ciccosanti F, Alonzi T, Nardacci R, Ippolito G, Tripodi M, Garcia‐Monzon C, Lo Iacono O, Piacentini M, Fimia GM. Autophagy protects cells from HCV‐induced defects in lipid metabolism. Gastroenterology 2012;142:644–653.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>142</number></detail><extent unit="pages"><start>644</start><end>653</end></extent></part><relatedItem type="host"><titleInfo><title>Gastroenterology</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>142</number></detail><extent unit="pages"><start>644</start><end>653</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0121"><titleInfo><title>Autophagy is increased in postmortem brains of persons with HIV‐1‐associated encephalitis</title></titleInfo><name type="personal"><namePart type="given">D</namePart><namePart type="family">Zhou</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E</namePart><namePart type="family">Masliah</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SA</namePart><namePart type="family">Spector</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Zhou D, Masliah E, Spector SA. Autophagy is increased in postmortem brains of persons with HIV‐1‐associated encephalitis. J Infect Dis 2011;203:1647–1657.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>203</number></detail><extent unit="pages"><start>1647</start><end>1657</end></extent></part><relatedItem type="host"><titleInfo><title>J Infect Dis</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>203</number></detail><extent unit="pages"><start>1647</start><end>1657</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0122"><titleInfo><title>Age‐dependent molecular alterations in the autophagy pathway in HIVE patients and in a gp120 tg mouse model: Reversal with beclin‐1 gene transfer</title></titleInfo><name type="personal"><namePart type="given">J</namePart><namePart type="family">Fields</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">W</namePart><namePart type="family">Dumaop</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E</namePart><namePart type="family">Rockenstein</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Mante</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Spencer</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">I</namePart><namePart type="family">Grant</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Ellis</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Letendre</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Patrick</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Adame</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E</namePart><namePart type="family">Masliah</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Fields J, Dumaop W, Rockenstein E, Mante M, Spencer B, Grant I, Ellis R, Letendre S, Patrick C, Adame A, Masliah E. Age‐dependent molecular alterations in the autophagy pathway in HIVE patients and in a gp120 tg mouse model: Reversal with beclin‐1 gene transfer. J Neurovirol 2013;19:89–101.</note><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>19</number></detail><extent unit="pages"><start>89</start><end>101</end></extent></part><relatedItem type="host"><titleInfo><title>J Neurovirol</title></titleInfo><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>19</number></detail><extent unit="pages"><start>89</start><end>101</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0123"><titleInfo><title>Inhibition of human immunodeficiency virus type‐1 through autophagy</title></titleInfo><name type="personal"><namePart type="given">GR</namePart><namePart type="family">Campbell</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SA</namePart><namePart type="family">Spector</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Campbell GR, Spector SA. Inhibition of human immunodeficiency virus type‐1 through autophagy. Curr Opin Microbiol 2013.</note><part><date>2013</date></part><relatedItem type="host"><titleInfo><title>Curr Opin Microbiol</title></titleInfo><part><date>2013</date></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0124"><titleInfo><title>Aloe emodin inhibits the cytotoxic action of tumor necrosis factor</title></titleInfo><name type="personal"><namePart type="given">L</namePart><namePart type="family">Harhaji</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Mijatovic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">Maksimovic‐Ivanic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">Popadic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Isakovic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Todorovic‐Markovic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">V</namePart><namePart type="family">Trajkovic</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Harhaji L, Mijatovic S, Maksimovic‐Ivanic D, Popadic D, Isakovic A, Todorovic‐Markovic B, Trajkovic V. Aloe emodin inhibits the cytotoxic action of tumor necrosis factor. Eur J Pharmacol 2007;568:248–259.</note><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>568</number></detail><extent unit="pages"><start>248</start><end>259</end></extent></part><relatedItem type="host"><titleInfo><title>Eur J Pharmacol</title></titleInfo><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>568</number></detail><extent unit="pages"><start>248</start><end>259</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0125"><titleInfo><title>Synergistic antiglioma action of hyperthermia and nitric oxide</title></titleInfo><name type="personal"><namePart type="given">K</namePart><namePart type="family">Janjetovic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Misirkic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Vucicevic</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Harhaji</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">V</namePart><namePart type="family">Trajkovic</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Janjetovic K, Misirkic M, Vucicevic L, Harhaji L, Trajkovic V. Synergistic antiglioma action of hyperthermia and nitric oxide. Eur J Pharmacol 2008;583:1–10.</note><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>583</number></detail><extent unit="pages"><start>1</start><end>10</end></extent></part><relatedItem type="host"><titleInfo><title>Eur J Pharmacol</title></titleInfo><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>583</number></detail><extent unit="pages"><start>1</start><end>10</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0126"><titleInfo><title>Blocking hypoxia‐induced autophagy in tumors restores cytotoxic T‐cell activity and promotes regression</title></titleInfo><name type="personal"><namePart type="given">MZ</namePart><namePart type="family">Noman</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Janji</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Kaminska</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Van Moer</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Pierson</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Przanowski</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Buart</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Berchem</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Romero</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F</namePart><namePart type="family">Mami‐Chouaib</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Chouaib</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Noman MZ, Janji B, Kaminska B, Van Moer K, Pierson S, Przanowski P, Buart S, Berchem G, Romero P, Mami‐Chouaib F, Chouaib S. Blocking hypoxia‐induced autophagy in tumors restores cytotoxic T‐cell activity and promotes regression. Cancer Res 2011;71:5976–5986.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>71</number></detail><extent unit="pages"><start>5976</start><end>5986</end></extent></part><relatedItem type="host"><titleInfo><title>Cancer Res</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>71</number></detail><extent unit="pages"><start>5976</start><end>5986</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0127"><titleInfo><title>Differential role of autophagy in CD4 T cells and macrophages during X4 and R5 HIV‐1 infection</title></titleInfo><name type="personal"><namePart type="given">L</namePart><namePart type="family">Espert</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Varbanov</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">V</namePart><namePart type="family">Robert‐Hebmann</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Sagnier</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">I</namePart><namePart type="family">Robbins</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F</namePart><namePart type="family">Sanchez</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">V</namePart><namePart type="family">Lafont</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Biard‐Piechaczyk</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Espert L, Varbanov M, Robert‐Hebmann V, Sagnier S, Robbins I, Sanchez F, Lafont V, Biard‐Piechaczyk M. Differential role of autophagy in CD4 T cells and macrophages during X4 and R5 HIV‐1 infection. PLoS One 2009;4:e5787.</note><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>4</number></detail><extent unit="pages"><start>e5787</start></extent></part><relatedItem type="host"><titleInfo><title>PLoS One</title></titleInfo><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>4</number></detail><extent unit="pages"><start>e5787</start></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0128"><titleInfo><title>HIV‐1 inhibits autophagy in bystander macrophage/monocytic cells through Src‐Akt and STAT3</title></titleInfo><name type="personal"><namePart type="given">J</namePart><namePart type="family">Van Grol</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Subauste</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">RM</namePart><namePart type="family">Andrade</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Fujinaga</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Nelson</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">CS</namePart><namePart type="family">Subauste</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Van Grol J, Subauste C, Andrade RM, Fujinaga K, Nelson J, Subauste CS. HIV‐1 inhibits autophagy in bystander macrophage/monocytic cells through Src‐Akt and STAT3. PLoS One 2010;5:e11733.</note><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>5</number></detail><extent unit="pages"><start>e11733</start></extent></part><relatedItem type="host"><titleInfo><title>PLoS One</title></titleInfo><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>5</number></detail><extent unit="pages"><start>e11733</start></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0129"><titleInfo><title>Inhibition of HIV‐1 replication by hydroxychloroquine: Mechanism of action and comparison with zidovudine</title></titleInfo><name type="personal"><namePart type="given">G</namePart><namePart type="family">Chiang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Sassaroli</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Louie</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">H</namePart><namePart type="family">Chen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">VJ</namePart><namePart type="family">Stecher</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Sperber</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Chiang G, Sassaroli M, Louie M, Chen H, Stecher VJ, Sperber K. Inhibition of HIV‐1 replication by hydroxychloroquine: Mechanism of action and comparison with zidovudine. Clin Ther 1996;18:1080–1092.</note><part><date>1996</date><detail type="volume"><caption>vol.</caption><number>18</number></detail><extent unit="pages"><start>1080</start><end>1092</end></extent></part><relatedItem type="host"><titleInfo><title>Clin Ther</title></titleInfo><part><date>1996</date><detail type="volume"><caption>vol.</caption><number>18</number></detail><extent unit="pages"><start>1080</start><end>1092</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0130"><titleInfo><title>Comparison of hydroxychloroquine with zidovudine in asymptomatic patients infected with human immunodeficiency virus type 1</title></titleInfo><name type="personal"><namePart type="given">K</namePart><namePart type="family">Sperber</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Chiang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">H</namePart><namePart type="family">Chen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">W</namePart><namePart type="family">Ross</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E</namePart><namePart type="family">Chusid</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Gonchar</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Chow</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">O</namePart><namePart type="family">Liriano</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Sperber K, Chiang G, Chen H, Ross W, Chusid E, Gonchar M, Chow R, Liriano O. Comparison of hydroxychloroquine with zidovudine in asymptomatic patients infected with human immunodeficiency virus type 1. Clin Ther 1997;19:913–923.</note><part><date>1997</date><detail type="volume"><caption>vol.</caption><number>19</number></detail><extent unit="pages"><start>913</start><end>923</end></extent></part><relatedItem type="host"><titleInfo><title>Clin Ther</title></titleInfo><part><date>1997</date><detail type="volume"><caption>vol.</caption><number>19</number></detail><extent unit="pages"><start>913</start><end>923</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0131"><titleInfo><title>Hydroxychloroquine treatment of patients with human immunodeficiency virus type 1</title></titleInfo><name type="personal"><namePart type="given">K</namePart><namePart type="family">Sperber</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Louie</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Kraus</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Proner</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E</namePart><namePart type="family">Sapira</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Lin</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">V</namePart><namePart type="family">Stecher</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Mayer</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Sperber K, Louie M, Kraus T, Proner J, Sapira E, Lin S, Stecher V, Mayer L. Hydroxychloroquine treatment of patients with human immunodeficiency virus type 1. Clin Ther 1995;17:622–636.</note><part><date>1995</date><detail type="volume"><caption>vol.</caption><number>17</number></detail><extent unit="pages"><start>622</start><end>636</end></extent></part><relatedItem type="host"><titleInfo><title>Clin Ther</title></titleInfo><part><date>1995</date><detail type="volume"><caption>vol.</caption><number>17</number></detail><extent unit="pages"><start>622</start><end>636</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0132"><titleInfo><title>Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs</title></titleInfo><name type="personal"><namePart type="given">F</namePart><namePart type="family">Luciani</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Spada</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">De Milito</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Molinari</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Rivoltini</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Montinaro</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Marra</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Lugini</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Logozzi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F</namePart><namePart type="family">Lozupone</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Federici</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E</namePart><namePart type="family">Iessi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Parmiani</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Arancia</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F</namePart><namePart type="family">Belardelli</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Fais</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Luciani F, Spada M, De Milito A, Molinari A, Rivoltini L, Montinaro A, Marra M, Lugini L, Logozzi M, Lozupone F, Federici C, Iessi E, Parmiani G, Arancia G, Belardelli F, Fais S. Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs. J Natl Cancer Inst 2004;96:1702–1713.</note><part><date>2004</date><detail type="volume"><caption>vol.</caption><number>96</number></detail><extent unit="pages"><start>1702</start><end>1713</end></extent></part><relatedItem type="host"><titleInfo><title>J Natl Cancer Inst</title></titleInfo><part><date>2004</date><detail type="volume"><caption>vol.</caption><number>96</number></detail><extent unit="pages"><start>1702</start><end>1713</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0133"><titleInfo><title>Proton pump inhibitors induce apoptosis of human B‐cell tumors through a caspase‐independent mechanism involving reactive oxygen species</title></titleInfo><name type="personal"><namePart type="given">A</namePart><namePart type="family">Milito</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E</namePart><namePart type="family">Iessi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Logozzi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F</namePart><namePart type="family">Lozupone</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Spada</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">ML</namePart><namePart type="family">Marino</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Federici</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Perdicchio</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Matarrese</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Lugini</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Nilsson</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Fais</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">De Milito A, Iessi E, Logozzi M, Lozupone F, Spada M, Marino ML, Federici C, Perdicchio M, Matarrese P, Lugini L, Nilsson A, Fais S. Proton pump inhibitors induce apoptosis of human B‐cell tumors through a caspase‐independent mechanism involving reactive oxygen species. Cancer Res 2007;67:5408–5417.</note><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>67</number></detail><extent unit="pages"><start>5408</start><end>5417</end></extent></part><relatedItem type="host"><titleInfo><title>Cancer Res</title></titleInfo><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>67</number></detail><extent unit="pages"><start>5408</start><end>5417</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0134"><titleInfo><title>Omeprazole inhibits proliferation and modulates autophagy in pancreatic cancer cells</title></titleInfo><name type="personal"><namePart type="given">A</namePart><namePart type="family">Udelnow</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Kreyes</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Ellinger</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Landfester</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Walther</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Klapperstueck</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Wohlrab</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">Henne‐Bruns</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">U</namePart><namePart type="family">Knippschild</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Wurl</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Udelnow A, Kreyes A, Ellinger S, Landfester K, Walther P, Klapperstueck T, Wohlrab J, Henne‐Bruns D, Knippschild U, Wurl P. Omeprazole inhibits proliferation and modulates autophagy in pancreatic cancer cells. PLoS One 2011;6:e20143.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>6</number></detail><extent unit="pages"><start>e20143</start></extent></part><relatedItem type="host"><titleInfo><title>PLoS One</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>6</number></detail><extent unit="pages"><start>e20143</start></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0135"><titleInfo><title>Proton pump inhibition induces autophagy as a survival mechanism following oxidative stress in human melanoma cells</title></titleInfo><name type="personal"><namePart type="given">ML</namePart><namePart type="family">Marino</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Fais</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Djavaheri‐Mergny</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Villa</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Meschini</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F</namePart><namePart type="family">Lozupone</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Venturi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Della Mina</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Pattingre</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Rivoltini</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Codogno</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">De Milito</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Marino ML, Fais S, Djavaheri‐Mergny M, Villa A, Meschini S, Lozupone F, Venturi G, Della Mina P, Pattingre S, Rivoltini L, Codogno P, De Milito A. Proton pump inhibition induces autophagy as a survival mechanism following oxidative stress in human melanoma cells. Cell Death Dis 2010;1:e87.</note><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>1</number></detail><extent unit="pages"><start>e87</start></extent></part><relatedItem type="host"><titleInfo><title>Cell Death Dis</title></titleInfo><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>1</number></detail><extent unit="pages"><start>e87</start></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0136"><titleInfo><title>Identification of a candidate therapeutic autophagy‐inducing peptide</title></titleInfo><name type="personal"><namePart type="given">S</namePart><namePart type="family">Shoji‐Kawata</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Sumpter</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Leveno</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">GR</namePart><namePart type="family">Campbell</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Z</namePart><namePart type="family">Zou</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Kinch</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">AD</namePart><namePart type="family">Wilkins</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Q</namePart><namePart type="family">Sun</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Pallauf</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">MacDuff</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Huerta</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">HW</namePart><namePart type="family">Virgin</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JB</namePart><namePart type="family">Helms</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Eerland</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SA</namePart><namePart type="family">Tooze</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Xavier</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">DJ</namePart><namePart type="family">Lenschow</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Yamamoto</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">King</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">O</namePart><namePart type="family">Lichtarge</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">NV</namePart><namePart type="family">Grishin</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SA</namePart><namePart type="family">Spector</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">DV</namePart><namePart type="family">Kaloyanova</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Levine</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Shoji‐Kawata S, Sumpter R, Leveno M, Campbell GR, Zou Z, Kinch L, Wilkins AD, Sun Q, Pallauf K, MacDuff D, Huerta C, Virgin HW, Helms JB, Eerland R, Tooze SA, Xavier R, Lenschow DJ, Yamamoto A, King D, Lichtarge O, Grishin NV, Spector SA, Kaloyanova DV, Levine B Identification of a candidate therapeutic autophagy‐inducing peptide. Nature 2013;494:201–206.</note><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>494</number></detail><extent unit="pages"><start>201</start><end>206</end></extent></part><relatedItem type="host"><titleInfo><title>Nature</title></titleInfo><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>494</number></detail><extent unit="pages"><start>201</start><end>206</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0137"><titleInfo><title>Toll‐like receptor 8 ligands activate a vitamin D mediated autophagic response that inhibits human immunodeficiency virus type 1</title></titleInfo><name type="personal"><namePart type="given">GR</namePart><namePart type="family">Campbell</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SA</namePart><namePart type="family">Spector</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Campbell GR, Spector SA. Toll‐like receptor 8 ligands activate a vitamin D mediated autophagic response that inhibits human immunodeficiency virus type 1. PLoS Pathog 2012;8:e1003017.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>8</number></detail><extent unit="pages"><start>e1003017</start></extent></part><relatedItem type="host"><titleInfo><title>PLoS Pathog</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>8</number></detail><extent unit="pages"><start>e1003017</start></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0138"><titleInfo><title>Compromising mitochondrial function with the antiretroviral drug efavirenz induces cell survival‐promoting autophagy</title></titleInfo><name type="personal"><namePart type="given">N</namePart><namePart type="family">Apostolova</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">LJ</namePart><namePart type="family">Gomez‐Sucerquia</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Gortat</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Blas‐Garcia</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JV</namePart><namePart type="family">Esplugues</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Apostolova N, Gomez‐Sucerquia LJ, Gortat A, Blas‐Garcia A, Esplugues JV. Compromising mitochondrial function with the antiretroviral drug efavirenz induces cell survival‐promoting autophagy. Hepatology 2011;54:1009–1019.</note><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>54</number></detail><extent unit="pages"><start>1009</start><end>1019</end></extent></part><relatedItem type="host"><titleInfo><title>Hepatology</title></titleInfo><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>54</number></detail><extent unit="pages"><start>1009</start><end>1019</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0139"><titleInfo><title>Nelfinavir, A lead HIV protease inhibitor, is a broad‐spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo</title></titleInfo><name type="personal"><namePart type="given">JJ</namePart><namePart type="family">Gills</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Lopiccolo</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Tsurutani</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">RH</namePart><namePart type="family">Shoemaker</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">CJ</namePart><namePart type="family">Best</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MS</namePart><namePart type="family">Abu‐Asab</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Borojerdi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">NA</namePart><namePart type="family">Warfel</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">ER</namePart><namePart type="family">Gardner</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Danish</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MC</namePart><namePart type="family">Hollander</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Kawabata</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Tsokos</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">WD</namePart><namePart type="family">Figg</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">PS</namePart><namePart type="family">Steeg</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">PA</namePart><namePart type="family">Dennis</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Gills JJ, Lopiccolo J, Tsurutani J, Shoemaker RH, Best CJ, Abu‐Asab MS, Borojerdi J, Warfel NA, Gardner ER, Danish M, Hollander MC, Kawabata S, Tsokos M, Figg WD, Steeg PS, Dennis PA. Nelfinavir, A lead HIV protease inhibitor, is a broad‐spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo. Clin Cancer Res 2007;13:5183–5194.</note><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>13</number></detail><extent unit="pages"><start>5183</start><end>5194</end></extent></part><relatedItem type="host"><titleInfo><title>Clin Cancer Res</title></titleInfo><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>13</number></detail><extent unit="pages"><start>5183</start><end>5194</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0140"><titleInfo><title>The protease inhibitor atazanavir triggers autophagy and mitophagy in human preadipocytes</title></titleInfo><name type="personal"><namePart type="given">L</namePart><namePart type="family">Gibellini</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">De Biasi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Pinti</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Nasi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Riccio</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Carnevale</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">GM</namePart><namePart type="family">Cavallini</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">FJ</namePart><namePart type="family">Sala de Oyanguren</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JE</namePart><namePart type="family">O'Connor</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Mussini</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">De Pol</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Cossarizza</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Gibellini L, De Biasi S, Pinti M, Nasi M, Riccio M, Carnevale G, Cavallini GM, Sala de Oyanguren FJ, O'Connor JE, Mussini C, De Pol A, Cossarizza A. The protease inhibitor atazanavir triggers autophagy and mitophagy in human preadipocytes. Aids 2012;26:2017–2026.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>26</number></detail><extent unit="pages"><start>2017</start><end>2026</end></extent></part><relatedItem type="host"><titleInfo><title>Aids</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>26</number></detail><extent unit="pages"><start>2017</start><end>2026</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0141"><titleInfo><title>CH05–10, a novel indinavir analog, is a broad‐spectrum antitumor agent that induces cell cycle arrest, apoptosis, endoplasmic reticulum stress and autophagy</title></titleInfo><name type="personal"><namePart type="given">J</namePart><namePart type="family">You</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Z</namePart><namePart type="family">He</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Chen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Deng</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">W</namePart><namePart type="family">Liu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Qin</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F</namePart><namePart type="family">Qiu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">X</namePart><namePart type="family">Chen</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">You J, He Z, Chen L, Deng G, Liu W, Qin L, Qiu F, Chen X. CH05–10, a novel indinavir analog, is a broad‐spectrum antitumor agent that induces cell cycle arrest, apoptosis, endoplasmic reticulum stress and autophagy. Cancer Sci 2010;101:2644–2651.</note><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>101</number></detail><extent unit="pages"><start>2644</start><end>2651</end></extent></part><relatedItem type="host"><titleInfo><title>Cancer Sci</title></titleInfo><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>101</number></detail><extent unit="pages"><start>2644</start><end>2651</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0142"><titleInfo><title>Oncolytic adenovirus: Preclinical and clinical studies in patients with human malignant gliomas</title></titleInfo><name type="personal"><namePart type="given">H</namePart><namePart type="family">Jiang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Gomez‐Manzano</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">FF</namePart><namePart type="family">Lang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Alemany</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Fueyo</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Jiang H, Gomez‐Manzano C, Lang FF, Alemany R, Fueyo J. Oncolytic adenovirus: Preclinical and clinical studies in patients with human malignant gliomas. Curr Gene Ther 2009;9:422–427.</note><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>9</number></detail><extent unit="pages"><start>422</start><end>427</end></extent></part><relatedItem type="host"><titleInfo><title>Curr Gene Ther</title></titleInfo><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>9</number></detail><extent unit="pages"><start>422</start><end>427</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0143"><titleInfo><title>Inhibition of autophagy enhances the effects of E1A‐defective oncolytic adenovirus dl922–947 against glioma cells in vitro and in vivo</title></titleInfo><name type="personal"><namePart type="given">G</namePart><namePart type="family">Botta</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Passaro</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Libertini</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Abagnale</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Barbato</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">AS</namePart><namePart type="family">Maione</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Hallden</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F</namePart><namePart type="family">Beguinot</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Formisano</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Portella</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Botta G, Passaro C, Libertini S, Abagnale A, Barbato S, Maione AS, Hallden G, Beguinot F, Formisano P, Portella G. Inhibition of autophagy enhances the effects of E1A‐defective oncolytic adenovirus dl922–947 against glioma cells in vitro and in vivo. Hum Gene Ther 2012;23:623–634.</note><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>23</number></detail><extent unit="pages"><start>623</start><end>634</end></extent></part><relatedItem type="host"><titleInfo><title>Hum Gene Ther</title></titleInfo><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>23</number></detail><extent unit="pages"><start>623</start><end>634</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0144"><titleInfo><title>Autophagic cell death of malignant glioma cells induced by a conditionally replicating adenovirus</title></titleInfo><name type="personal"><namePart type="given">H</namePart><namePart type="family">Ito</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">H</namePart><namePart type="family">Aoki</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F</namePart><namePart type="family">Kuhnel</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Kondo</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Kubicka</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Wirth</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E</namePart><namePart type="family">Iwado</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Iwamaru</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Fujiwara</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">KR</namePart><namePart type="family">Hess</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">FF</namePart><namePart type="family">Lang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Sawaya</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Kondo</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Ito H, Aoki H, Kuhnel F, Kondo Y, Kubicka S, Wirth T, Iwado E, Iwamaru A, Fujiwara K, Hess KR, Lang FF, Sawaya R, Kondo S. Autophagic cell death of malignant glioma cells induced by a conditionally replicating adenovirus. J Natl Cancer Inst 2006;98:625–636.</note><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>98</number></detail><extent unit="pages"><start>625</start><end>636</end></extent></part><relatedItem type="host"><titleInfo><title>J Natl Cancer Inst</title></titleInfo><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>98</number></detail><extent unit="pages"><start>625</start><end>636</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0145"><titleInfo><title>Examination of the therapeutic potential of Delta‐24‐RGD in brain tumor stem cells: Role of autophagic cell death</title></titleInfo><name type="personal"><namePart type="given">H</namePart><namePart type="family">Jiang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Gomez‐Manzano</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">H</namePart><namePart type="family">Aoki</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MM</namePart><namePart type="family">Alonso</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Kondo</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F</namePart><namePart type="family">McCormick</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Xu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Kondo</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">BN</namePart><namePart type="family">Bekele</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">H</namePart><namePart type="family">Colman</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">FF</namePart><namePart type="family">Lang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Fueyo</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Jiang H, Gomez‐Manzano C, Aoki H, Alonso MM, Kondo S, McCormick F, Xu J, Kondo Y, Bekele BN, Colman H, Lang FF, Fueyo J. Examination of the therapeutic potential of Delta‐24‐RGD in brain tumor stem cells: Role of autophagic cell death. J Natl Cancer Inst 2007;99:1410–1414.</note><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>99</number></detail><extent unit="pages"><start>1410</start><end>1414</end></extent></part><relatedItem type="host"><titleInfo><title>J Natl Cancer Inst</title></titleInfo><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>99</number></detail><extent unit="pages"><start>1410</start><end>1414</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0146"><titleInfo><title>Oncolytic adenovirus with temozolomide induces autophagy and antitumor immune responses in cancer patients</title></titleInfo><name type="personal"><namePart type="given">I</namePart><namePart type="family">Liikanen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Ahtiainen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">ML</namePart><namePart type="family">Hirvinen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Bramante</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">V</namePart><namePart type="family">Cerullo</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Nokisalmi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">O</namePart><namePart type="family">Hemminki</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">I</namePart><namePart type="family">Diaconu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Pesonen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Koski</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Kangasniemi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SK</namePart><namePart type="family">Pesonen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Oksanen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Laasonen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Partanen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Joensuu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F</namePart><namePart type="family">Zhao</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Kanerva</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Hemminki</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Liikanen I, Ahtiainen L, Hirvinen ML, Bramante S, Cerullo V, Nokisalmi P, Hemminki O, Diaconu I, Pesonen S, Koski A, Kangasniemi L, Pesonen SK, Oksanen M, Laasonen L, Partanen K, Joensuu T, Zhao F, Kanerva A, Hemminki A. Oncolytic adenovirus with temozolomide induces autophagy and antitumor immune responses in cancer patients. Mol Ther 2013;21:1212–1223.</note><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>21</number></detail><extent unit="pages"><start>1212</start><end>1223</end></extent></part><relatedItem type="host"><titleInfo><title>Mol Ther</title></titleInfo><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>21</number></detail><extent unit="pages"><start>1212</start><end>1223</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="med21303-cit-0147"><titleInfo><title>Targeting autophagy to enhance oncolytic virus‐based cancer therapy</title></titleInfo><name type="personal"><namePart type="given">S</namePart><namePart type="family">Meng</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Xu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Wu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Ding</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Meng S, Xu J, Wu Y, Ding C. Targeting autophagy to enhance oncolytic virus‐based cancer therapy. Expert Opin Biol Ther 2013;13:863–873.</note><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>13</number></detail><extent unit="pages"><start>863</start><end>873</end></extent></part><relatedItem type="host"><titleInfo><title>Expert Opin Biol Ther</title></titleInfo><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>13</number></detail><extent unit="pages"><start>863</start><end>873</end></extent></part></relatedItem></relatedItem><identifier type="istex">A5DBC900895F3312DBAB477FD6F5F6250A93CDCB</identifier><identifier type="ark">ark:/67375/WNG-6LTJWFXN-B</identifier><identifier type="DOI">10.1002/med.21303</identifier><identifier type="ArticleID">MED21303</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2014 Wiley Periodicals, Inc.© 2013 Wiley Periodicals, Inc.</accessCondition><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-L0C46X92-X">wiley</recordContentSource><recordOrigin>Converted from (version ) to MODS version 3.6.</recordOrigin><recordCreationDate encoding="w3cdtf">2019-11-15</recordCreationDate></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-6LTJWFXN-B/record.json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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