Sarcoidosis – a clinically orientated review
Identifieur interne : 000197 ( Istex/Corpus ); précédent : 000196; suivant : 000198Sarcoidosis – a clinically orientated review
Auteurs : Mahmoud Dastoori ; Stefano Fedele ; Jair C. Leao ; Stephen R. PorterSource :
- Journal of Oral Pathology & Medicine [ 0904-2512 ] ; 2013-04.
English descriptors
- Teeft :
- Asymptomatic, Baughman, Cardiac, Chloroquine, Clin, Corticosteroid, Crit, Cutaneous, Dastoori, Epidemiology, Erythema nodosum, Granuloma, Granulomatous, Hepatic, Hepatic sarcoidosis, Macrophage, Neopterin, Nodule, Ocular sarcoidosis, Oral pathol, Orientated, Orientated review dastoori, Pathol, Pulmonary sarcoidosis, Respir, Respir crit care, Sarcoid, Sarcoidosis, Sarcoidosis vasc, Vasc.
Abstract
Sarcoidosis is a multisystem disease of unknown cause. Sarcoidosis can affect all individuals with any race, sex, or age but commonly affects young‐ and middle‐aged adults and usually presents with bilateral hilar lymphadenopathy, pulmonary infiltration, skin and ocular lesions. Other organs can also be affected. Diagnosis is established when clinical and radiological findings are supported by the presence of non‐caseating epithelioid cell granulomas, however, local sarcoid reactions and granulomas of known cause should be excluded. The optimal management has not been well defined yet, although corticosteroids remain the mainstay of treatment, there is little evidence on which to base the indications for treatment including dosage and duration of therapy. Certain clinical features are helpful in the prognosis of the condition that can vary from a self‐limiting course to progressive life‐threatening fibrosis of the vital organs.
Url:
DOI: 10.1111/j.1600-0714.2012.01198.x
Links to Exploration step
ISTEX:D22791B9A899B442A6D06EDECD30FAF92074E6FELe document en format XML
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Sarcoidosis can affect all individuals with any race, sex, or age but commonly affects young‐ and middle‐aged adults and usually presents with bilateral hilar lymphadenopathy, pulmonary infiltration, skin and ocular lesions. Other organs can also be affected. Diagnosis is established when clinical and radiological findings are supported by the presence of non‐caseating epithelioid cell granulomas, however, local sarcoid reactions and granulomas of known cause should be excluded. The optimal management has not been well defined yet, although corticosteroids remain the mainstay of treatment, there is little evidence on which to base the indications for treatment including dosage and duration of therapy. Certain clinical features are helpful in the prognosis of the condition that can vary from a self‐limiting course to progressive life‐threatening fibrosis of the vital organs.</div></front></TEI><istex><corpusName>wiley</corpusName><keywords><teeft><json:string>sarcoidosis</json:string><json:string>corticosteroid</json:string><json:string>respir</json:string><json:string>nodule</json:string><json:string>pulmonary sarcoidosis</json:string><json:string>hepatic</json:string><json:string>pathol</json:string><json:string>clin</json:string><json:string>granuloma</json:string><json:string>crit</json:string><json:string>granulomatous</json:string><json:string>asymptomatic</json:string><json:string>oral pathol</json:string><json:string>respir crit care</json:string><json:string>cutaneous</json:string><json:string>orientated</json:string><json:string>baughman</json:string><json:string>sarcoid</json:string><json:string>orientated review dastoori</json:string><json:string>dastoori</json:string><json:string>macrophage</json:string><json:string>epidemiology</json:string><json:string>sarcoidosis vasc</json:string><json:string>neopterin</json:string><json:string>chloroquine</json:string><json:string>vasc</json:string><json:string>ocular sarcoidosis</json:string><json:string>hepatic sarcoidosis</json:string><json:string>erythema nodosum</json:string><json:string>cardiac</json:string><json:string>ocular</json:string><json:string>lesion</json:string><json:string>chronic sarcoidosis</json:string><json:string>lupus pernio</json:string><json:string>ocular involvement</json:string><json:string>cutaneous sarcoidosis</json:string><json:string>caucasian</json:string><json:string>anterior uveitis</json:string><json:string>weight loss</json:string><json:string>constitutional symptoms</json:string><json:string>oral corticosteroids</json:string><json:string>serum level</json:string><json:string>sarcoidosis patients</json:string><json:string>corticosteroid therapy</json:string><json:string>white patients</json:string><json:string>skin lesions</json:string><json:string>pulmonary involvement</json:string><json:string>vital organs</json:string><json:string>semin respir crit care</json:string><json:string>sace level</json:string><json:string>syndrome</json:string><json:string>sarcoid granulomas</json:string><json:string>systemic involvement</json:string><json:string>asymptomatic sarcoidosis</json:string><json:string>differential diagnosis</json:string><json:string>joint statement</json:string><json:string>organ involvement</json:string><json:string>disease activity</json:string><json:string>systemic corticosteroids</json:string><json:string>mild disease</json:string><json:string>other treatment</json:string><json:string>neurological involvement</json:string><json:string>systemic therapy</json:string><json:string>clinical course</json:string><json:string>environmental factors</json:string><json:string>neurological sarcoidosis</json:string><json:string>common cause</json:string><json:string>sudden death</json:string><json:string>acute form</json:string><json:string>mortality rate</json:string><json:string>higher mortality rates</json:string><json:string>genetic factors</json:string><json:string>clinical features</json:string><json:string>unknown origin</json:string><json:string>lung function</json:string><json:string>access research group</json:string><json:string>case control etiologic study</json:string><json:string>arch intern</json:string><json:string>little evidence</json:string><json:string>ocular lesions</json:string><json:string>clin chest</json:string><json:string>hepatic nodules</json:string><json:string>portal hypertension</json:string><json:string>occupational risk factors</json:string><json:string>gastric variceal</json:string><json:string>unknown cause</json:string><json:string>arch neurol</json:string><json:string>therapeutic considerations</json:string><json:string>refractory neurosarcoidosis</json:string><json:string>systemic sarcoidosis</json:string><json:string>arch dermatol</json:string><json:string>cardiac sarcoidosis</json:string><json:string>arch pathol</json:string><json:string>myocardial sarcoidosis</json:string><json:string>sarcoidosis therapy</json:string></teeft></keywords><author><json:item><name>Mahmoud Dastoori</name><affiliations><json:string>Department of Maxillofacial Medicine and Surgery, Oral Medicine unit, UCL Eastman Dental Institute, London, UK</json:string></affiliations></json:item><json:item><name>Stefano Fedele</name><affiliations><json:string>Department of Maxillofacial Medicine and Surgery, Oral Medicine unit, UCL Eastman Dental Institute, London, UK</json:string></affiliations></json:item><json:item><name>Jair C. 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Certain clinical features are helpful in the prognosis of the condition that can vary from a self‐limiting course to progressive life‐threatening fibrosis of the vital organs.</p></abstract><textClass><keywords><term xml:id="jop1198-kwd-0001">oral lesions</term><term xml:id="jop1198-kwd-0002">oral medicine</term><term xml:id="jop1198-kwd-0003">sarcoidosis</term></keywords><keywords rend="articleCategory"><term>Review Article</term></keywords><keywords rend="tocHeading1"><term>Review article</term></keywords></textClass><langUsage><language ident="en"></language></langUsage></profileDesc><revisionDesc><change when="2019-12-20" who="#istex" xml:id="pub2tei">formatting</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-K8QVNKJ5-1/fulltext.txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component type="serialArticle" version="2.0" xml:id="jop1198" xml:lang="en"><header><publicationMeta level="product"><doi origin="wiley" registered="yes">10.1111/(ISSN)1600-0714</doi><issn type="print">0904-2512</issn><issn type="electronic">1600-0714</issn><idGroup><id type="product" value="JOP"></id></idGroup><titleGroup><title sort="JOURNAL OF ORAL PATHOLOGY AND MEDICINE" type="main">Journal of Oral Pathology & Medicine</title><title type="short">J Oral Pathol Med</title></titleGroup></publicationMeta><publicationMeta level="part" position="04104"><doi origin="wiley">10.1111/jop.2013.42.issue-4</doi><copyright ownership="publisher">Copyright © 2013 John Wiley & Sons A/S</copyright><numberingGroup><numbering type="journalVolume" number="42">42</numbering><numbering type="journalIssue">4</numbering></numberingGroup><coverDate startDate="2013-04">April 2013</coverDate></publicationMeta><publicationMeta level="unit" position="10" status="forIssue" type="reviewArticle"><doi>10.1111/j.1600-0714.2012.01198.x</doi><idGroup><id type="unit" value="JOP1198"></id></idGroup><countGroup><count number="9" type="pageTotal"></count></countGroup><titleGroup><title type="articleCategory">Review Article</title><title type="tocHeading1"><i>Review article</i></title></titleGroup><copyright ownership="publisher">© 2012 John Wiley & Sons A/S. All rights reserved</copyright><eventGroup><event date="2012-06-12" type="manuscriptAccepted"></event><event agent="SPS" date="2012-07-04" type="xmlCreated"></event><event type="publishedOnlineEarlyUnpaginated" date="2012-07-28"></event><event type="firstOnline" date="2012-07-28"></event><event type="publishedOnlineFinalForm" date="2013-04-01"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-01-31"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.6.4 mode:FullText" date="2015-10-03"></event></eventGroup><numberingGroup><numbering type="pageFirst">281</numbering><numbering type="pageLast">289</numbering></numberingGroup><correspondenceTo>Correspondence: Stephen Porter, Professor, Director's Office, UCL Eastman Dental Institute, 256 Gray's Inn Road, London WC1X 8LD, UK. Tel: +44 (0) 203456 1038, Fax: +44 (0) 203456 1039, E‐mail: <email>s.porter@ucl.ac.uk</email></correspondenceTo><selfCitationGroup><citation type="self" xml:id="jop1198-cit-0126"><i>J Oral Pathol Med</i> (2013) 42: 281−289</citation></selfCitationGroup><linkGroup><link type="toTypesetVersion" href="file:JOP.JOP1198.pdf"></link></linkGroup></publicationMeta><contentMeta><titleGroup><title type="main">Sarcoidosis – a clinically orientated review</title><title type="shortAuthors">Dastoori et al.</title></titleGroup><creators><creator affiliationRef="#jop1198-aff-0001" creatorRole="author" xml:id="jop1198-cr-0001"><personName><givenNames>Mahmoud</givenNames> <familyName>Dastoori</familyName></personName></creator><creator affiliationRef="#jop1198-aff-0001" creatorRole="author" xml:id="jop1198-cr-0002"><personName><givenNames>Stefano</givenNames> <familyName>Fedele</familyName></personName></creator><creator affiliationRef="#jop1198-aff-0001 #jop1198-aff-0002" creatorRole="author" xml:id="jop1198-cr-0003"><personName><givenNames>Jair C.</givenNames> <familyName>Leao</familyName></personName></creator><creator affiliationRef="#jop1198-aff-0001" corresponding="yes" creatorRole="author" xml:id="jop1198-cr-0004"><personName><givenNames>Stephen R.</givenNames> <familyName>Porter</familyName></personName></creator></creators><affiliationGroup><affiliation countryCode="GB" type="organization" xml:id="jop1198-aff-0001"><orgDiv>Department of Maxillofacial Medicine and Surgery</orgDiv> <orgName>Oral Medicine unit</orgName> <orgName>UCL Eastman Dental Institute</orgName> <address><city>London</city> <country>UK</country></address></affiliation><affiliation countryCode="BR" type="organization" xml:id="jop1198-aff-0002"><orgDiv>Departamento de Clinica e Odontologia Preventiva</orgDiv> <orgName>Universidade Federal de Pernambuco</orgName> <address><city>Recife</city> <country>Brazil</country></address></affiliation></affiliationGroup><keywordGroup type="author"><keyword xml:id="jop1198-kwd-0001">oral lesions</keyword><keyword xml:id="jop1198-kwd-0002">oral medicine</keyword><keyword xml:id="jop1198-kwd-0003">sarcoidosis</keyword></keywordGroup><abstractGroup><abstract type="main" xml:id="jop1198-abs-0001"><p>Sarcoidosis is a multisystem disease of unknown cause. Sarcoidosis can affect all individuals with any race, sex, or age but commonly affects young‐ and middle‐aged adults and usually presents with bilateral hilar lymphadenopathy, pulmonary infiltration, skin and ocular lesions. Other organs can also be affected. Diagnosis is established when clinical and radiological findings are supported by the presence of non‐caseating epithelioid cell granulomas, however, local sarcoid reactions and granulomas of known cause should be excluded. The optimal management has not been well defined yet, although corticosteroids remain the mainstay of treatment, there is little evidence on which to base the indications for treatment including dosage and duration of therapy. Certain clinical features are helpful in the prognosis of the condition that can vary from a self‐limiting course to progressive life‐threatening fibrosis of the vital organs.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Sarcoidosis – a clinically orientated review</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Sarcoidosis – a clinically orientated review</title></titleInfo><name type="personal"><namePart type="given">Mahmoud</namePart><namePart type="family">Dastoori</namePart><affiliation>Department of Maxillofacial Medicine and Surgery, Oral Medicine unit, UCL Eastman Dental Institute, London, UK</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Stefano</namePart><namePart type="family">Fedele</namePart><affiliation>Department of Maxillofacial Medicine and Surgery, Oral Medicine unit, UCL Eastman Dental Institute, London, UK</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jair C.</namePart><namePart type="family">Leao</namePart><affiliation>Department of Maxillofacial Medicine and Surgery, Oral Medicine unit, UCL Eastman Dental Institute, London, UK</affiliation><affiliation>Departamento de Clinica e Odontologia Preventiva, Universidade Federal de Pernambuco, Recife, Brazil</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Stephen R.</namePart><namePart type="family">Porter</namePart><affiliation>Department of Maxillofacial Medicine and Surgery, Oral Medicine unit, UCL Eastman Dental Institute, London, UK</affiliation><affiliation>E-mail: s.porter@ucl.ac.uk</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="review-article" displayLabel="reviewArticle" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-L5L7X3NF-P">review-article</genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><dateIssued encoding="w3cdtf">2013-04</dateIssued><dateCreated encoding="w3cdtf">2012-07-04</dateCreated><dateValid encoding="w3cdtf">2012-06-12</dateValid><edition>J Oral Pathol Med (2013) 42: 281−289</edition><copyrightDate encoding="w3cdtf">2013</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><abstract>Sarcoidosis is a multisystem disease of unknown cause. Sarcoidosis can affect all individuals with any race, sex, or age but commonly affects young‐ and middle‐aged adults and usually presents with bilateral hilar lymphadenopathy, pulmonary infiltration, skin and ocular lesions. Other organs can also be affected. Diagnosis is established when clinical and radiological findings are supported by the presence of non‐caseating epithelioid cell granulomas, however, local sarcoid reactions and granulomas of known cause should be excluded. The optimal management has not been well defined yet, although corticosteroids remain the mainstay of treatment, there is little evidence on which to base the indications for treatment including dosage and duration of therapy. Certain clinical features are helpful in the prognosis of the condition that can vary from a self‐limiting course to progressive life‐threatening fibrosis of the vital organs.</abstract><subject><genre>keywords</genre><topic>oral lesions</topic><topic>oral medicine</topic><topic>sarcoidosis</topic></subject><relatedItem type="host"><titleInfo><title>Journal of Oral Pathology & Medicine</title></titleInfo><titleInfo type="abbreviated"><title>J Oral Pathol Med</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><subject><genre>article-category</genre><topic>Review Article</topic><topic>Review article</topic></subject><identifier type="ISSN">0904-2512</identifier><identifier type="eISSN">1600-0714</identifier><identifier type="DOI">10.1111/(ISSN)1600-0714</identifier><identifier type="PublisherID">JOP</identifier><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>42</number></detail><detail type="issue"><caption>no.</caption><number>4</number></detail><extent unit="pages"><start>281</start><end>289</end><total>9</total></extent></part></relatedItem><relatedItem type="references" displayLabel="jop1198-cit-0001"><titleInfo><title>[Epidemiology, presentation forms, radiological stage and diagnostic methods of sarcoidosis in the area of Leon (2001–2008)]</title></titleInfo><name type="personal"><namePart type="given">GS</namePart><namePart type="family">Fernandez</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">GR</namePart><namePart type="family">Lopez</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Fernandez GS, Lopez GR. 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