Intravenous Immunoglobulin in Lupus Panniculitis
Identifieur interne : 000159 ( Istex/Corpus ); précédent : 000158; suivant : 000160Intravenous Immunoglobulin in Lupus Panniculitis
Auteurs : João Espírito Santo ; M. F. Gomes ; M. J. Gomes ; L. Peixoto ; S. C. Pereira ; A. Acabado ; J. Freitas ; G. Vinhas De SousaSource :
- Clinical Reviews in Allergy & Immunology [ 1080-0549 ] ; 2010-04-01.
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- KwdEn :
Abstract
Abstract: Systemic lupus erythematosus (SLE) is a disease of unknown cause that may involve one or many organ or systems. Skin involvement is a major feature in this disease, and a wide variety of skin conditions may be present. Lupus erythematosus panniculitis (LEP) constitutes a rare form of cutaneous lupus characterized by recurrent nodular or plaque lesions that can vary from a benign and mild course to a more disfiguring disease. Initial therapy includes corticosteroids, antimalarials, and azathioprine and, in refractory cases, two antimalarials in association, mycophenolate mofetil, or other immunomodulators. Intravenous immuglobulin (IVIG) is used in many autoimmune disorders, like in SLE, although clinical trials have not yet taken place. In this report, we review skin manifestations of SLE and their treatment, IVIG, and finally a case of LEP successfully treated with IVIG when other therapy modalities failed.
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DOI: 10.1007/s12016-009-8162-x
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ISTEX:DCAC39A9829CF6CCCF31537E959F88B5AF6A35F9Le document en format XML
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Pereira</name><affiliation><mods:affiliation>Departement of Medicine 1, Hospital Santa Maria, Lisbon, Portugal</mods:affiliation></affiliation></author><author><name sortKey="Acabado, A" sort="Acabado, A" uniqKey="Acabado A" first="A." last="Acabado">A. Acabado</name><affiliation><mods:affiliation>Departement of Medicine 1, Hospital Santa Maria, Lisbon, Portugal</mods:affiliation></affiliation></author><author><name sortKey="Freitas, J" sort="Freitas, J" uniqKey="Freitas J" first="J." last="Freitas">J. Freitas</name><affiliation><mods:affiliation>Departement of Dermatology, Hospital Santa Maria, Lisbon, Portugal</mods:affiliation></affiliation></author><author><name sortKey="De Sousa, G Vinhas" sort="De Sousa, G Vinhas" uniqKey="De Sousa G" first="G. Vinhas" last="De Sousa">G. Vinhas De Sousa</name><affiliation><mods:affiliation>Departement of Medicine 1, Hospital Santa Maria, Lisbon, Portugal</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Clinical Reviews in Allergy & Immunology</title><title level="j" type="abbrev">Clinic Rev Allerg Immunol</title><idno type="ISSN">1080-0549</idno><idno type="eISSN">1559-0267</idno><imprint><publisher>Humana Press Inc</publisher><pubPlace>New York</pubPlace><date type="published" when="2010-04-01">2010-04-01</date><biblScope unit="volume">38</biblScope><biblScope unit="issue">2-3</biblScope><biblScope unit="page" from="307">307</biblScope><biblScope unit="page" to="318">318</biblScope></imprint><idno type="ISSN">1080-0549</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1080-0549</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>IVIG</term><term>LEP</term><term>SLE</term><term>Skin manifestations of SLE</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: Systemic lupus erythematosus (SLE) is a disease of unknown cause that may involve one or many organ or systems. Skin involvement is a major feature in this disease, and a wide variety of skin conditions may be present. Lupus erythematosus panniculitis (LEP) constitutes a rare form of cutaneous lupus characterized by recurrent nodular or plaque lesions that can vary from a benign and mild course to a more disfiguring disease. Initial therapy includes corticosteroids, antimalarials, and azathioprine and, in refractory cases, two antimalarials in association, mycophenolate mofetil, or other immunomodulators. Intravenous immuglobulin (IVIG) is used in many autoimmune disorders, like in SLE, although clinical trials have not yet taken place. In this report, we review skin manifestations of SLE and their treatment, IVIG, and finally a case of LEP successfully treated with IVIG when other therapy modalities failed.</div></front></TEI><istex><corpusName>springer-journals</corpusName><author><json:item><name>João Espírito Santo</name><affiliations><json:string>Departement of Medicine 1, Hospital Santa Maria, Lisbon, Portugal</json:string><json:string>E-mail: joao.es@iol.pt</json:string></affiliations></json:item><json:item><name>M. F. Gomes</name><affiliations><json:string>Departement of Medicine 1, Hospital Santa Maria, Lisbon, Portugal</json:string></affiliations></json:item><json:item><name>M. J. Gomes</name><affiliations><json:string>Departement of Medicine 1, Hospital Santa Maria, Lisbon, Portugal</json:string></affiliations></json:item><json:item><name>L. Peixoto</name><affiliations><json:string>Departement of Medicine 1, Hospital Santa Maria, Lisbon, Portugal</json:string></affiliations></json:item><json:item><name>S. 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Vinhas de Sousa</name><affiliations><json:string>Departement of Medicine 1, Hospital Santa Maria, Lisbon, Portugal</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>SLE</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Skin manifestations of SLE</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>LEP</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>IVIG</value></json:item></subject><articleId><json:string>8162</json:string><json:string>s12016-009-8162-x</json:string></articleId><arkIstex>ark:/67375/VQC-NB7K30HF-F</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>OriginalPaper</json:string></originalGenre><abstract>Abstract: Systemic lupus erythematosus (SLE) is a disease of unknown cause that may involve one or many organ or systems. Skin involvement is a major feature in this disease, and a wide variety of skin conditions may be present. Lupus erythematosus panniculitis (LEP) constitutes a rare form of cutaneous lupus characterized by recurrent nodular or plaque lesions that can vary from a benign and mild course to a more disfiguring disease. Initial therapy includes corticosteroids, antimalarials, and azathioprine and, in refractory cases, two antimalarials in association, mycophenolate mofetil, or other immunomodulators. Intravenous immuglobulin (IVIG) is used in many autoimmune disorders, like in SLE, although clinical trials have not yet taken place. 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Skin involvement is a major feature in this disease, and a wide variety of skin conditions may be present. Lupus erythematosus panniculitis (LEP) constitutes a rare form of cutaneous lupus characterized by recurrent nodular or plaque lesions that can vary from a benign and mild course to a more disfiguring disease. Initial therapy includes corticosteroids, antimalarials, and azathioprine and, in refractory cases, two antimalarials in association, mycophenolate mofetil, or other immunomodulators. Intravenous immuglobulin (IVIG) is used in many autoimmune disorders, like in SLE, although clinical trials have not yet taken place. In this report, we review skin manifestations of SLE and their treatment, IVIG, and finally a case of LEP successfully treated with IVIG when other therapy modalities failed.</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>SLE</term></item><item><term>Skin manifestations of SLE</term></item><item><term>LEP</term></item><item><term>IVIG</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>Medicine & Public Health</head><item><term>Internal Medicine</term></item><item><term>Immunology</term></item><item><term>Allergology</term></item></list></keywords></textClass></profileDesc><revisionDesc><change 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Panniculitis</ArticleTitle><ArticleFirstPage>307</ArticleFirstPage><ArticleLastPage>318</ArticleLastPage><ArticleHistory><RegistrationDate><Year>2009</Year><Month>6</Month><Day>15</Day></RegistrationDate><OnlineDate><Year>2009</Year><Month>6</Month><Day>27</Day></OnlineDate></ArticleHistory><ArticleCopyright><CopyrightHolderName>Humana Press Inc.</CopyrightHolderName><CopyrightYear>2009</CopyrightYear></ArticleCopyright><ArticleGrants Type="Regular"><MetadataGrant Grant="OpenAccess"></MetadataGrant><AbstractGrant Grant="OpenAccess"></AbstractGrant><BodyPDFGrant Grant="Restricted"></BodyPDFGrant><BodyHTMLGrant Grant="Restricted"></BodyHTMLGrant><BibliographyGrant Grant="Restricted"></BibliographyGrant><ESMGrant Grant="Restricted"></ESMGrant></ArticleGrants></ArticleInfo><ArticleHeader><AuthorGroup><Author AffiliationIDS="Aff1" CorrespondingAffiliationID="Aff1"><AuthorName DisplayOrder="Western"><GivenName>João</GivenName><FamilyName>Espírito Santo</FamilyName></AuthorName><Contact><Email>joao.es@iol.pt</Email></Contact></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>M.</GivenName><GivenName>F.</GivenName><FamilyName>Gomes</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>M.</GivenName><GivenName>J.</GivenName><FamilyName>Gomes</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>L.</GivenName><FamilyName>Peixoto</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>S.</GivenName><FamilyName>C. Pereira</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>A.</GivenName><FamilyName>Acabado</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff2"><AuthorName DisplayOrder="Western"><GivenName>J.</GivenName><FamilyName>Freitas</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>G.</GivenName><GivenName>Vinhas</GivenName><Particle>de</Particle><FamilyName>Sousa</FamilyName></AuthorName></Author><Affiliation ID="Aff1"><OrgDivision>Departement of Medicine 1</OrgDivision><OrgName>Hospital Santa Maria</OrgName><OrgAddress><City>Lisbon</City><Country Code="PT">Portugal</Country></OrgAddress></Affiliation><Affiliation ID="Aff2"><OrgDivision>Departement of Dermatology</OrgDivision><OrgName>Hospital Santa Maria</OrgName><OrgAddress><City>Lisbon</City><Country Code="PT">Portugal</Country></OrgAddress></Affiliation></AuthorGroup><Abstract ID="Abs1" Language="En" OutputMedium="All"><Heading>Abstract</Heading><Para>Systemic lupus erythematosus (SLE) is a disease of unknown cause that may involve one or many organ or systems. Skin involvement is a major feature in this disease, and a wide variety of skin conditions may be present. Lupus erythematosus panniculitis (LEP) constitutes a rare form of cutaneous lupus characterized by recurrent nodular or plaque lesions that can vary from a benign and mild course to a more disfiguring disease. Initial therapy includes corticosteroids, antimalarials, and azathioprine and, in refractory cases, two antimalarials in association, mycophenolate mofetil, or other immunomodulators. Intravenous immuglobulin (IVIG) is used in many autoimmune disorders, like in SLE, although clinical trials have not yet taken place. In this report, we review skin manifestations of SLE and their treatment, IVIG, and finally a case of LEP successfully treated with IVIG when other therapy modalities failed.</Para></Abstract><KeywordGroup Language="En" OutputMedium="All"><Heading>Keywords</Heading><Keyword>SLE</Keyword><Keyword>Skin manifestations of SLE</Keyword><Keyword>LEP</Keyword><Keyword>IVIG</Keyword></KeywordGroup></ArticleHeader><NoBody></NoBody></Article></Issue></Volume></Journal></Publisher></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Intravenous Immunoglobulin in Lupus Panniculitis</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Intravenous Immunoglobulin in Lupus Panniculitis</title></titleInfo><name type="personal" displayLabel="corresp"><namePart type="given">João</namePart><namePart type="family">Espírito Santo</namePart><affiliation>Departement of Medicine 1, Hospital Santa Maria, Lisbon, Portugal</affiliation><affiliation>E-mail: joao.es@iol.pt</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M.</namePart><namePart type="given">F.</namePart><namePart type="family">Gomes</namePart><affiliation>Departement of Medicine 1, Hospital Santa Maria, Lisbon, Portugal</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M.</namePart><namePart type="given">J.</namePart><namePart type="family">Gomes</namePart><affiliation>Departement of Medicine 1, Hospital Santa Maria, Lisbon, Portugal</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L.</namePart><namePart type="family">Peixoto</namePart><affiliation>Departement of Medicine 1, Hospital Santa Maria, Lisbon, Portugal</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S.</namePart><namePart type="family">C. Pereira</namePart><affiliation>Departement of Medicine 1, Hospital Santa Maria, Lisbon, Portugal</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A.</namePart><namePart type="family">Acabado</namePart><affiliation>Departement of Medicine 1, Hospital Santa Maria, Lisbon, Portugal</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J.</namePart><namePart type="family">Freitas</namePart><affiliation>Departement of Dermatology, Hospital Santa Maria, Lisbon, Portugal</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G.</namePart><namePart type="given">Vinhas</namePart><namePart type="family">de Sousa</namePart><affiliation>Departement of Medicine 1, Hospital Santa Maria, Lisbon, Portugal</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="OriginalPaper" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-1JC4F85T-7">research-article</genre><originInfo><publisher>Humana Press Inc</publisher><place><placeTerm type="text">New York</placeTerm></place><dateIssued encoding="w3cdtf">2010-04-01</dateIssued><copyrightDate encoding="w3cdtf">2009</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><abstract lang="en">Abstract: Systemic lupus erythematosus (SLE) is a disease of unknown cause that may involve one or many organ or systems. Skin involvement is a major feature in this disease, and a wide variety of skin conditions may be present. Lupus erythematosus panniculitis (LEP) constitutes a rare form of cutaneous lupus characterized by recurrent nodular or plaque lesions that can vary from a benign and mild course to a more disfiguring disease. Initial therapy includes corticosteroids, antimalarials, and azathioprine and, in refractory cases, two antimalarials in association, mycophenolate mofetil, or other immunomodulators. Intravenous immuglobulin (IVIG) is used in many autoimmune disorders, like in SLE, although clinical trials have not yet taken place. In this report, we review skin manifestations of SLE and their treatment, IVIG, and finally a case of LEP successfully treated with IVIG when other therapy modalities failed.</abstract><subject lang="en"><genre>Keywords</genre><topic>SLE</topic><topic>Skin manifestations of SLE</topic><topic>LEP</topic><topic>IVIG</topic></subject><relatedItem type="host"><titleInfo><title>Clinical Reviews in Allergy & Immunology</title></titleInfo><titleInfo type="abbreviated"><title>Clinic Rev Allerg Immunol</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><originInfo><publisher>Springer</publisher><dateIssued encoding="w3cdtf">2010-03-30</dateIssued><copyrightDate encoding="w3cdtf">2010</copyrightDate></originInfo><subject><genre>Medicine & Public Health</genre><topic>Internal Medicine</topic><topic>Immunology</topic><topic>Allergology</topic></subject><identifier type="ISSN">1080-0549</identifier><identifier type="eISSN">1559-0267</identifier><identifier type="JournalID">12016</identifier><identifier type="IssueArticleCount">26</identifier><identifier type="VolumeIssueCount">3</identifier><part><date>2010</date><detail type="issue"><title>Challenges for the Autoimmunologist: Yehuda Shoenfeld, MD, FRCP</title></detail><detail type="volume"><number>38</number><caption>vol.</caption></detail><detail type="issue"><number>2-3</number><caption>no.</caption></detail><extent unit="pages"><start>307</start><end>318</end></extent></part><recordInfo><recordOrigin>Springer Science+Business Media, LLC, 2010</recordOrigin></recordInfo></relatedItem><identifier type="istex">DCAC39A9829CF6CCCF31537E959F88B5AF6A35F9</identifier><identifier type="ark">ark:/67375/VQC-NB7K30HF-F</identifier><identifier type="DOI">10.1007/s12016-009-8162-x</identifier><identifier type="ArticleID">8162</identifier><identifier type="ArticleID">s12016-009-8162-x</identifier><accessCondition type="use and reproduction" contentType="copyright">Humana Press Inc., 2009</accessCondition><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-3XSW68JL-F">springer</recordContentSource><recordOrigin>Humana Press Inc., 2009</recordOrigin></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/ark:/67375/VQC-NB7K30HF-F/record.json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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