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Calcification in choroidal melanoma after transpupillary thermotherapy

Identifieur interne : 001231 ( Istex/Checkpoint ); précédent : 001230; suivant : 001232

Calcification in choroidal melanoma after transpupillary thermotherapy

Auteurs : Hayyam Kiratli [Turquie] ; Sevgül Bilgiç [Turquie]

Source :

RBID : ISTEX:951AEC3D74144013A55863DC2B8485AECD79AAF5

English descriptors

Abstract

Abstract: PURPOSE: To report the response of calcification in choroidal melanoma after transpupillary thermotherapy.METHODS: Interventional case report. A 66-year-old male with a posterior uveal melanoma measuring 10 × 8 × 4.4 mm underwent infrared diode laser transpupillary thermotherapy three times, each 12 weeks apart. For each treatment, a 3-mm spot size of 1-minute duration was used, and the power setting varied between 450 mW and 500 mW.RESULTS: Two months after the last transpupillary thermotherapy session, A- and B-mode echographic patterns strongly suggestive of intratumor calcification were observed. The tumor regressed to 2.8 mm in thickness, but calcification persisted. Local recurrence or distant metastasis was not detected during a follow-up of 14 months.CONCLUSION: Clinically detectable calcification is extremely rare in choroidal melanomas. Tumor regression with slowly progressive calcification may occur after transpupillary thermotherapy.

Url:
DOI: 10.1016/S0002-9394(01)01186-2


Affiliations:


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ISTEX:951AEC3D74144013A55863DC2B8485AECD79AAF5

Le document en format XML

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<term>Brachytherapy</term>
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<term>Iris melanoma</term>
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<term>Malignant melanoma</term>
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<term>Spect</term>
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<term>Thermotherapy</term>
<term>Transpupillary</term>
<term>Transpupillary thermotherapy</term>
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<div type="abstract" xml:lang="en">Abstract: PURPOSE: To report the response of calcification in choroidal melanoma after transpupillary thermotherapy.METHODS: Interventional case report. A 66-year-old male with a posterior uveal melanoma measuring 10 × 8 × 4.4 mm underwent infrared diode laser transpupillary thermotherapy three times, each 12 weeks apart. For each treatment, a 3-mm spot size of 1-minute duration was used, and the power setting varied between 450 mW and 500 mW.RESULTS: Two months after the last transpupillary thermotherapy session, A- and B-mode echographic patterns strongly suggestive of intratumor calcification were observed. The tumor regressed to 2.8 mm in thickness, but calcification persisted. Local recurrence or distant metastasis was not detected during a follow-up of 14 months.CONCLUSION: Clinically detectable calcification is extremely rare in choroidal melanomas. Tumor regression with slowly progressive calcification may occur after transpupillary thermotherapy.</div>
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