Genetically Encoded pH Sensor for Tracking Surface Proteins through Endocytosis
Identifieur interne : 000405 ( Istex/Checkpoint ); précédent : 000404; suivant : 000406Genetically Encoded pH Sensor for Tracking Surface Proteins through Endocytosis
Auteurs : Anmol Grover [États-Unis] ; Brigitte F. Schmidt [États-Unis] ; Russell D. Salter [États-Unis] ; Simon C. Watkins [États-Unis] ; Alan S. Waggoner [États-Unis] ; Marcel P. Bruchez [États-Unis]Source :
- Angewandte Chemie [ 0044-8249 ] ; 2012-05-14.
English descriptors
- Teeft :
- Angewandte chemie, Biological sciences, Biosensor, Carrier control, Cell biol, Cell surface proteins, Chem, Dendritic cells, Donor cells, Endocytic, Endocytic compartments, Energy transfer, Green emission, Imaging, Molecular biosensor, Plasma membrane, Receptor, Receptor trafficking, Recipient cell, Recipient cells, Significant change, Spectral overlap, Surface proteins, Surface selection, Trafficking, Verlag gmbh, Vesicle, Weinheim angew.
Abstract
Verkehrsüberwachung: Ein Tandemfarbstoff aus einem FRET‐Akzeptor und einem fluorogenen Donor funktioniert als ratiometrischer pH‐Indikator für Zelloberflächen, mit dem sich nach Internalisierung der Proteintransport während der Endozytose verfolgen lässt. Der Sensor wurde auf zweierlei Weise eingesetzt: zur Analyse der Agonist‐abhängigen Internalisierung des β2‐adrenergen Rezeptors (siehe Schema) und zur Untersuchung des direkten Antigentransfers von der Oberfläche zum Endosom zwischen dendritischen Zellen.
Url:
DOI: 10.1002/ange.201108107
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
ISTEX:F3EFBEF63FC4A0A3EA96BC1D18B4B1CFE739CF31Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Genetically Encoded pH Sensor for Tracking Surface Proteins through Endocytosis</title><author><name sortKey="Grover, Anmol" sort="Grover, Anmol" uniqKey="Grover A" first="Anmol" last="Grover">Anmol Grover</name></author><author><name sortKey="Schmidt, Brigitte F" sort="Schmidt, Brigitte F" uniqKey="Schmidt B" first="Brigitte F." last="Schmidt">Brigitte F. Schmidt</name></author><author><name sortKey="Salter, Russell D" sort="Salter, Russell D" uniqKey="Salter R" first="Russell D." last="Salter">Russell D. Salter</name></author><author><name sortKey="Watkins, Simon C" sort="Watkins, Simon C" uniqKey="Watkins S" first="Simon C." last="Watkins">Simon C. Watkins</name></author><author><name sortKey="Waggoner, Alan S" sort="Waggoner, Alan S" uniqKey="Waggoner A" first="Alan S." last="Waggoner">Alan S. Waggoner</name></author><author><name sortKey="Bruchez, Marcel P" sort="Bruchez, Marcel P" uniqKey="Bruchez M" first="Marcel P." last="Bruchez">Marcel P. Bruchez</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:F3EFBEF63FC4A0A3EA96BC1D18B4B1CFE739CF31</idno><date when="2012" year="2012">2012</date><idno type="doi">10.1002/ange.201108107</idno><idno type="url">https://api.istex.fr/ark:/67375/WNG-S99WNX0N-7/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">001892</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001892</idno><idno type="wicri:Area/Istex/Curation">001892</idno><idno type="wicri:Area/Istex/Checkpoint">000405</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000405</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Genetically Encoded pH Sensor for Tracking Surface Proteins through Endocytosis</title><author><name sortKey="Grover, Anmol" sort="Grover, Anmol" uniqKey="Grover A" first="Anmol" last="Grover">Anmol Grover</name><affiliation wicri:level="4"><country>États-Unis</country><placeName><settlement type="city">Pittsburgh</settlement><region type="state">Pennsylvanie</region></placeName><orgName type="university">Université Carnegie-Mellon</orgName></affiliation></author><author><name sortKey="Schmidt, Brigitte F" sort="Schmidt, Brigitte F" uniqKey="Schmidt B" first="Brigitte F." last="Schmidt">Brigitte F. Schmidt</name><affiliation wicri:level="4"><country>États-Unis</country><placeName><settlement type="city">Pittsburgh</settlement><region type="state">Pennsylvanie</region></placeName><orgName type="university">Université Carnegie-Mellon</orgName></affiliation></author><author><name sortKey="Salter, Russell D" sort="Salter, Russell D" uniqKey="Salter R" first="Russell D." last="Salter">Russell D. Salter</name><affiliation wicri:level="3"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Cell Biology and Physiology, University of Pittsburgh School of Medicine, Pittsburgh</wicri:regionArea><placeName><settlement type="city">Pittsburgh</settlement><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Watkins, Simon C" sort="Watkins, Simon C" uniqKey="Watkins S" first="Simon C." last="Watkins">Simon C. Watkins</name><affiliation wicri:level="3"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Cell Biology and Physiology, University of Pittsburgh School of Medicine, Pittsburgh</wicri:regionArea><placeName><settlement type="city">Pittsburgh</settlement><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Waggoner, Alan S" sort="Waggoner, Alan S" uniqKey="Waggoner A" first="Alan S." last="Waggoner">Alan S. Waggoner</name><affiliation wicri:level="4"><country>États-Unis</country><placeName><settlement type="city">Pittsburgh</settlement><region type="state">Pennsylvanie</region></placeName><orgName type="university">Université Carnegie-Mellon</orgName></affiliation></author><author><name sortKey="Bruchez, Marcel P" sort="Bruchez, Marcel P" uniqKey="Bruchez M" first="Marcel P." last="Bruchez">Marcel P. Bruchez</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName><wicri:cityArea>Department of Chemistry, Department of Biological Sciences and Molecular Biosensor and Imaging Center, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh</wicri:cityArea></affiliation><affiliation wicri:level="1"><country wicri:rule="url">États-Unis</country></affiliation><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName><wicri:cityArea>Correspondence address: Department of Chemistry, Department of Biological Sciences and Molecular Biosensor and Imaging Center, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh</wicri:cityArea></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Angewandte Chemie</title><title level="j" type="alt">ANGEWANDTE CHEMIE</title><idno type="ISSN">0044-8249</idno><idno type="eISSN">1521-3757</idno><imprint><biblScope unit="vol">124</biblScope><biblScope unit="issue">20</biblScope><biblScope unit="page" from="4922">4922</biblScope><biblScope unit="page" to="4926">4926</biblScope><biblScope unit="page-count">5</biblScope><publisher>WILEY‐VCH Verlag</publisher><pubPlace>Weinheim</pubPlace><date type="published" when="2012-05-14">2012-05-14</date></imprint><idno type="ISSN">0044-8249</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0044-8249</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Angewandte chemie</term><term>Biological sciences</term><term>Biosensor</term><term>Carrier control</term><term>Cell biol</term><term>Cell surface proteins</term><term>Chem</term><term>Dendritic cells</term><term>Donor cells</term><term>Endocytic</term><term>Endocytic compartments</term><term>Energy transfer</term><term>Green emission</term><term>Imaging</term><term>Molecular biosensor</term><term>Plasma membrane</term><term>Receptor</term><term>Receptor trafficking</term><term>Recipient cell</term><term>Recipient cells</term><term>Significant change</term><term>Spectral overlap</term><term>Surface proteins</term><term>Surface selection</term><term>Trafficking</term><term>Verlag gmbh</term><term>Vesicle</term><term>Weinheim angew</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="de">Verkehrsüberwachung: Ein Tandemfarbstoff aus einem FRET‐Akzeptor und einem fluorogenen Donor funktioniert als ratiometrischer pH‐Indikator für Zelloberflächen, mit dem sich nach Internalisierung der Proteintransport während der Endozytose verfolgen lässt. Der Sensor wurde auf zweierlei Weise eingesetzt: zur Analyse der Agonist‐abhängigen Internalisierung des β2‐adrenergen Rezeptors (siehe Schema) und zur Untersuchung des direkten Antigentransfers von der Oberfläche zum Endosom zwischen dendritischen Zellen.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Pennsylvanie</li></region><settlement><li>Pittsburgh</li></settlement><orgName><li>Université Carnegie-Mellon</li></orgName></list><tree><country name="États-Unis"><region name="Pennsylvanie"><name sortKey="Grover, Anmol" sort="Grover, Anmol" uniqKey="Grover A" first="Anmol" last="Grover">Anmol Grover</name></region><name sortKey="Bruchez, Marcel P" sort="Bruchez, Marcel P" uniqKey="Bruchez M" first="Marcel P." last="Bruchez">Marcel P. Bruchez</name><name sortKey="Bruchez, Marcel P" sort="Bruchez, Marcel P" uniqKey="Bruchez M" first="Marcel P." last="Bruchez">Marcel P. Bruchez</name><name sortKey="Bruchez, Marcel P" sort="Bruchez, Marcel P" uniqKey="Bruchez M" first="Marcel P." last="Bruchez">Marcel P. Bruchez</name><name sortKey="Salter, Russell D" sort="Salter, Russell D" uniqKey="Salter R" first="Russell D." last="Salter">Russell D. Salter</name><name sortKey="Schmidt, Brigitte F" sort="Schmidt, Brigitte F" uniqKey="Schmidt B" first="Brigitte F." last="Schmidt">Brigitte F. Schmidt</name><name sortKey="Waggoner, Alan S" sort="Waggoner, Alan S" uniqKey="Waggoner A" first="Alan S." last="Waggoner">Alan S. Waggoner</name><name sortKey="Watkins, Simon C" sort="Watkins, Simon C" uniqKey="Watkins S" first="Simon C." last="Watkins">Simon C. Watkins</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/Istex/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000405 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Checkpoint/biblio.hfd -nk 000405 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= ChloroquineV1
|flux= Istex
|étape= Checkpoint
|type= RBID
|clé= ISTEX:F3EFBEF63FC4A0A3EA96BC1D18B4B1CFE739CF31
|texte= Genetically Encoded pH Sensor for Tracking Surface Proteins through Endocytosis
}}
| This area was generated with Dilib version V0.6.33. |  |