ChloroquineV1, Hal, Curation, bibRecord, 000003

A New Xanthone from the Bark Extract of Rheedia acuminata and Antiplasmodial Activity of Its Major Compounds

Identifieur interne : 000003 ( Hal/Curation ); précédent : 000002; suivant : 000004

A New Xanthone from the Bark Extract of Rheedia acuminata and Antiplasmodial Activity of Its Major Compounds

Auteurs : Guillaume Marti [France] ; Véronique Eparvier [France] ; Marc Litaudon [France] ; Philippe Grellier [France] ; Francoise Guéritte [France]

Source :

Molecules [ 1420-3049 ] ; 2010-10.

RBID : Hal:mnhn-02047400

English descriptors

mix :
- Clusiaceae, Rheedia acuminata, antiplasmodial activity, cytotoxicity, xanthones.

Abstract

Bioassay-guided fractionation of the ethyl acetate bark extract of Rheedia acuminata led to the isolation of the new compound 1,5,6-trihydroxy-3-methoxy-7-geranyl-xanthone (1), together with four known compounds 2-5. These compounds were tested in vitro for their antiplasmodial activity on a chloroquine-resistant strain of Plasmodium falciparum (FcB1) and for their cytotoxicity against the human diploid embryonic lung cell line MRC-5.

Url:

https://hal-mnhn.archives-ouvertes.fr/mnhn-02047400

DOI: 10.3390/molecules15107106

Links toward previous steps (curation, corpus...)

to stream Hal, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000003

Links to Exploration step

Hal:mnhn-02047400

Le document en format XML

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A New Xanthone from the Bark Extract of Rheedia acuminata and Antiplasmodial Activity of Its Major Compounds

A New Xanthone from the Bark Extract of Rheedia acuminata and Antiplasmodial Activity of Its Major Compounds

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