ChloroquineV1, Hal, Checkpoint, bibRecord, 000213

Antiplasmodial phenolic compounds from Piptadenia pervillei.

Identifieur interne : 000213 ( Hal/Checkpoint ); précédent : 000212; suivant : 000214

Antiplasmodial phenolic compounds from Piptadenia pervillei.

Auteurs : Voahangy Ramanandraibe ; Philippe Grellier ; Marie-Thérèse Martin [France] ; Alexandre Deville ; Roger Joyeau ; David Ramanitrahasimbola ; Elisabeth Mouray ; Philippe Rasoanaivo ; Lengo Mambu

Source :

Planta Medica [ 0032-0943 ] ; 2008-03.

RBID : Hal:hal-00294805

Abstract

Piptadenia pervillei Vatke (Fabaceae) was selected from a screening programme devoted to the search of naturally-occuring antimalarial compounds from plants of Madagascar. Bioassay-guided fractionation of the ethyl acetate extract of the leaves led to the isolation of four phenolic compounds, (+)-catechin ( 1), (+)-catechin 5-gallate ( 2), (+)-catechin 3-gallate ( 3) and ethyl gallate ( 4). Structures were determined by NMR and mass spectroscopy. Compounds 2 and 3 displayed the highest in vitro activity against the chloroquine-resistant strain FcB1 of Plasmodium falciparum with IC (50) values of 1.2 microM and 1.0 microM, respectively, and no significant cytotoxicity against the human embryonic lung cells MRC-5 was measured (IC (50) values > 75 microM). Five analogues ( 5 - 9) of (+)-catechin 5-gallate ( 2) were synthesized and evaluated for their antiplasmodial activity.

Url:

https://hal.archives-ouvertes.fr/hal-00294805

DOI: 10.1055/s-2008-1034328

Links toward previous steps (curation, corpus...)

to stream Hal, to step Corpus: 000258
to stream Hal, to step Curation: 000258

Links to Exploration step

Hal:hal-00294805

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="it">Antiplasmodial phenolic compounds from Piptadenia pervillei.</title>
<author><name sortKey="Ramanandraibe, Voahangy" sort="Ramanandraibe, Voahangy" uniqKey="Ramanandraibe V" first="Voahangy" last="Ramanandraibe">Voahangy Ramanandraibe</name>
</author>
<author><name sortKey="Grellier, Philippe" sort="Grellier, Philippe" uniqKey="Grellier P" first="Philippe" last="Grellier">Philippe Grellier</name>
</author>
<author><name sortKey="Martin, Marie Therese" sort="Martin, Marie Therese" uniqKey="Martin M" first="Marie-Thérèse" last="Martin">Marie-Thérèse Martin</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-440" status="VALID">          <orgName>Institut de Chimie des Substances Naturelles</orgName>
          <orgName type="acronym">ICSN</orgName>
          <desc>            <address>              <addrLine>Avenue de la terrasse 91198 Gif sur yvette cedex</addrLine>
              <country key="FR"></country>
            </address>
          </desc>
          <listRelation>            <relation name="UPR2301" active="#struct-441569" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle name="UPR2301" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID">          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>            <address>              <country key="FR"></country>
            </address>
            <ref type="url">http://www.cnrs.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Deville, Alexandre" sort="Deville, Alexandre" uniqKey="Deville A" first="Alexandre" last="Deville">Alexandre Deville</name>
</author>
<author><name sortKey="Joyeau, Roger" sort="Joyeau, Roger" uniqKey="Joyeau R" first="Roger" last="Joyeau">Roger Joyeau</name>
</author>
<author><name sortKey="Ramanitrahasimbola, David" sort="Ramanitrahasimbola, David" uniqKey="Ramanitrahasimbola D" first="David" last="Ramanitrahasimbola">David Ramanitrahasimbola</name>
</author>
<author><name sortKey="Mouray, Elisabeth" sort="Mouray, Elisabeth" uniqKey="Mouray E" first="Elisabeth" last="Mouray">Elisabeth Mouray</name>
</author>
<author><name sortKey="Rasoanaivo, Philippe" sort="Rasoanaivo, Philippe" uniqKey="Rasoanaivo P" first="Philippe" last="Rasoanaivo">Philippe Rasoanaivo</name>
</author>
<author><name sortKey="Mambu, Lengo" sort="Mambu, Lengo" uniqKey="Mambu L" first="Lengo" last="Mambu">Lengo Mambu</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">HAL</idno>
<idno type="RBID">Hal:hal-00294805</idno>
<idno type="halId">hal-00294805</idno>
<idno type="halUri">https://hal.archives-ouvertes.fr/hal-00294805</idno>
<idno type="url">https://hal.archives-ouvertes.fr/hal-00294805</idno>
<idno type="doi">10.1055/s-2008-1034328</idno>
<date when="2008-03">2008-03</date>
<idno type="wicri:Area/Hal/Corpus">000258</idno>
<idno type="wicri:Area/Hal/Curation">000258</idno>
<idno type="wicri:Area/Hal/Checkpoint">000213</idno>
<idno type="wicri:explorRef" wicri:stream="Hal" wicri:step="Checkpoint">000213</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="it">Antiplasmodial phenolic compounds from Piptadenia pervillei.</title>
<author><name sortKey="Ramanandraibe, Voahangy" sort="Ramanandraibe, Voahangy" uniqKey="Ramanandraibe V" first="Voahangy" last="Ramanandraibe">Voahangy Ramanandraibe</name>
</author>
<author><name sortKey="Grellier, Philippe" sort="Grellier, Philippe" uniqKey="Grellier P" first="Philippe" last="Grellier">Philippe Grellier</name>
</author>
<author><name sortKey="Martin, Marie Therese" sort="Martin, Marie Therese" uniqKey="Martin M" first="Marie-Thérèse" last="Martin">Marie-Thérèse Martin</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-440" status="VALID">          <orgName>Institut de Chimie des Substances Naturelles</orgName>
          <orgName type="acronym">ICSN</orgName>
          <desc>            <address>              <addrLine>Avenue de la terrasse 91198 Gif sur yvette cedex</addrLine>
              <country key="FR"></country>
            </address>
          </desc>
          <listRelation>            <relation name="UPR2301" active="#struct-441569" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle name="UPR2301" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID">          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>            <address>              <country key="FR"></country>
            </address>
            <ref type="url">http://www.cnrs.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Deville, Alexandre" sort="Deville, Alexandre" uniqKey="Deville A" first="Alexandre" last="Deville">Alexandre Deville</name>
</author>
<author><name sortKey="Joyeau, Roger" sort="Joyeau, Roger" uniqKey="Joyeau R" first="Roger" last="Joyeau">Roger Joyeau</name>
</author>
<author><name sortKey="Ramanitrahasimbola, David" sort="Ramanitrahasimbola, David" uniqKey="Ramanitrahasimbola D" first="David" last="Ramanitrahasimbola">David Ramanitrahasimbola</name>
</author>
<author><name sortKey="Mouray, Elisabeth" sort="Mouray, Elisabeth" uniqKey="Mouray E" first="Elisabeth" last="Mouray">Elisabeth Mouray</name>
</author>
<author><name sortKey="Rasoanaivo, Philippe" sort="Rasoanaivo, Philippe" uniqKey="Rasoanaivo P" first="Philippe" last="Rasoanaivo">Philippe Rasoanaivo</name>
</author>
<author><name sortKey="Mambu, Lengo" sort="Mambu, Lengo" uniqKey="Mambu L" first="Lengo" last="Mambu">Lengo Mambu</name>
</author>
</analytic>
<idno type="DOI">10.1055/s-2008-1034328</idno>
<series><title level="j">Planta Medica</title>
<idno type="ISSN">0032-0943</idno>
<imprint><date type="datePub">2008-03</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">              <p>Piptadenia pervillei Vatke (Fabaceae) was selected from a screening programme devoted to the search of naturally-occuring antimalarial compounds from plants of Madagascar. Bioassay-guided fractionation of the ethyl acetate extract of the leaves led to the isolation of four phenolic compounds, (+)-catechin ( 1), (+)-catechin 5-gallate ( 2), (+)-catechin 3-gallate ( 3) and ethyl gallate ( 4). Structures were determined by NMR and mass spectroscopy. Compounds 2 and 3 displayed the highest in vitro activity against the chloroquine-resistant strain FcB1 of Plasmodium falciparum with IC (50) values of 1.2 microM and 1.0 microM, respectively, and no significant cytotoxicity against the human embryonic lung cells MRC-5 was measured (IC (50) values > 75 microM). Five analogues ( 5 - 9) of (+)-catechin 5-gallate ( 2) were synthesized and evaluated for their antiplasmodial activity.</p>
            </div>
</front>
</TEI>
<hal api="V3">          <titleStmt>            <title xml:lang="it">Antiplasmodial phenolic compounds from Piptadenia pervillei.</title>
            <author role="aut">              <persName>                <forename type="first">Voahangy</forename>
                <surname>Ramanandraibe</surname>
              </persName>
              <idno type="halauthorid">296238</idno>
            </author>
            <author role="aut">              <persName>                <forename type="first">Philippe</forename>
                <surname>Grellier</surname>
              </persName>
              <idno type="halauthorid">128593</idno>
            </author>
            <author role="aut">              <persName>                <forename type="first">Marie-Thérèse</forename>
                <surname>Martin</surname>
              </persName>
              <idno type="halauthorid">147373</idno>
              <affiliation ref="#struct-440"></affiliation>
            </author>
            <author role="aut">              <persName>                <forename type="first">Alexandre</forename>
                <surname>Deville</surname>
              </persName>
              <idno type="halauthorid">318332</idno>
            </author>
            <author role="aut">              <persName>                <forename type="first">Roger</forename>
                <surname>Joyeau</surname>
              </persName>
              <idno type="halauthorid">182312</idno>
            </author>
            <author role="aut">              <persName>                <forename type="first">David</forename>
                <surname>Ramanitrahasimbola</surname>
              </persName>
              <idno type="halauthorid">147374</idno>
            </author>
            <author role="aut">              <persName>                <forename type="first">Elisabeth</forename>
                <surname>Mouray</surname>
              </persName>
              <idno type="halauthorid">318333</idno>
            </author>
            <author role="aut">              <persName>                <forename type="first">Philippe</forename>
                <surname>Rasoanaivo</surname>
              </persName>
              <idno type="halauthorid">147375</idno>
            </author>
            <author role="aut">              <persName>                <forename type="first">Lengo</forename>
                <surname>Mambu</surname>
              </persName>
              <idno type="halauthorid">296240</idno>
            </author>
            <editor role="depositor">              <persName>                <forename>Jocelyne</forename>
                <surname>Brunet</surname>
              </persName>
              <email type="md5">5dd83d345d42190f284baae0dc2702e8</email>
              <email type="domain">icsn.cnrs-gif.fr</email>
            </editor>
          </titleStmt>
          <editionStmt>            <edition n="v1" type="current">              <date type="whenSubmitted">2008-07-10 15:03:08</date>
              <date type="whenModified">2018-01-11 06:14:40</date>
              <date type="whenReleased">2008-07-10 15:03:08</date>
              <date type="whenProduced">2008-03</date>
            </edition>
            <respStmt>              <resp>contributor</resp>
              <name key="103776">                <persName>                  <forename>Jocelyne</forename>
                  <surname>Brunet</surname>
                </persName>
                <email type="md5">5dd83d345d42190f284baae0dc2702e8</email>
                <email type="domain">icsn.cnrs-gif.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>            <distributor>CCSD</distributor>
            <idno type="halId">hal-00294805</idno>
            <idno type="halUri">https://hal.archives-ouvertes.fr/hal-00294805</idno>
            <idno type="halBibtex">ramanandraibe:hal-00294805</idno>
            <idno type="halRefHtml">Planta Medica, Georg Thieme Verlag, 2008, 74 (4), pp.417-21. ⟨10.1055/s-2008-1034328⟩</idno>
            <idno type="halRef">Planta Medica, Georg Thieme Verlag, 2008, 74 (4), pp.417-21. ⟨10.1055/s-2008-1034328⟩</idno>
          </publicationStmt>
          <seriesStmt>            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="ICSN">Collection des Publications de l'Institut de Chimie des Substances Naturelles, UPR2301, Gif sur Yvette</idno>
            <idno type="stamp" n="INC-CNRS">Institut de Chimie du CNRS</idno>
          </seriesStmt>
          <notesStmt>            <note type="audience" n="1">Not set</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>            <biblStruct>              <analytic>                <title xml:lang="it">Antiplasmodial phenolic compounds from Piptadenia pervillei.</title>
                <author role="aut">                  <persName>                    <forename type="first">Voahangy</forename>
                    <surname>Ramanandraibe</surname>
                  </persName>
                  <idno type="halauthorid">296238</idno>
                </author>
                <author role="aut">                  <persName>                    <forename type="first">Philippe</forename>
                    <surname>Grellier</surname>
                  </persName>
                  <idno type="halauthorid">128593</idno>
                </author>
                <author role="aut">                  <persName>                    <forename type="first">Marie-Thérèse</forename>
                    <surname>Martin</surname>
                  </persName>
                  <idno type="halauthorid">147373</idno>
                  <affiliation ref="#struct-440"></affiliation>
                </author>
                <author role="aut">                  <persName>                    <forename type="first">Alexandre</forename>
                    <surname>Deville</surname>
                  </persName>
                  <idno type="halauthorid">318332</idno>
                </author>
                <author role="aut">                  <persName>                    <forename type="first">Roger</forename>
                    <surname>Joyeau</surname>
                  </persName>
                  <idno type="halauthorid">182312</idno>
                </author>
                <author role="aut">                  <persName>                    <forename type="first">David</forename>
                    <surname>Ramanitrahasimbola</surname>
                  </persName>
                  <idno type="halauthorid">147374</idno>
                </author>
                <author role="aut">                  <persName>                    <forename type="first">Elisabeth</forename>
                    <surname>Mouray</surname>
                  </persName>
                  <idno type="halauthorid">318333</idno>
                </author>
                <author role="aut">                  <persName>                    <forename type="first">Philippe</forename>
                    <surname>Rasoanaivo</surname>
                  </persName>
                  <idno type="halauthorid">147375</idno>
                </author>
                <author role="aut">                  <persName>                    <forename type="first">Lengo</forename>
                    <surname>Mambu</surname>
                  </persName>
                  <idno type="halauthorid">296240</idno>
                </author>
              </analytic>
              <monogr>                <idno type="localRef">2008065</idno>
                <idno type="halJournalId" status="VALID">18058</idno>
                <idno type="issn">0032-0943</idno>
                <idno type="eissn">1439-0221</idno>
                <title level="j">Planta Medica</title>
                <imprint>                  <publisher>Georg Thieme Verlag</publisher>
                  <biblScope unit="volume">74</biblScope>
                  <biblScope unit="issue">4</biblScope>
                  <biblScope unit="pp">417-21</biblScope>
                  <date type="datePub">2008-03</date>
                </imprint>
              </monogr>
              <idno type="doi">10.1055/s-2008-1034328</idno>
              <idno type="pubmed">18484535</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>            <langUsage>              <language ident="en">English</language>
            </langUsage>
            <textClass>              <classCode scheme="halDomain" n="sdv.bc">Life Sciences [q-bio]/Cellular Biology</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
            </textClass>
            <abstract xml:lang="en">              <p>Piptadenia pervillei Vatke (Fabaceae) was selected from a screening programme devoted to the search of naturally-occuring antimalarial compounds from plants of Madagascar. Bioassay-guided fractionation of the ethyl acetate extract of the leaves led to the isolation of four phenolic compounds, (+)-catechin ( 1), (+)-catechin 5-gallate ( 2), (+)-catechin 3-gallate ( 3) and ethyl gallate ( 4). Structures were determined by NMR and mass spectroscopy. Compounds 2 and 3 displayed the highest in vitro activity against the chloroquine-resistant strain FcB1 of Plasmodium falciparum with IC (50) values of 1.2 microM and 1.0 microM, respectively, and no significant cytotoxicity against the human embryonic lung cells MRC-5 was measured (IC (50) values > 75 microM). Five analogues ( 5 - 9) of (+)-catechin 5-gallate ( 2) were synthesized and evaluated for their antiplasmodial activity.</p>
            </abstract>
          </profileDesc>
        </hal>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/Hal/Checkpoint

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000213 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Hal/Checkpoint/biblio.hfd -nk 000213 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    ChloroquineV1
   |flux=    Hal
   |étape=   Checkpoint
   |type=    RBID
   |clé=     Hal:hal-00294805
   |texte=   Antiplasmodial phenolic compounds from Piptadenia pervillei.
}}

This area was generated with Dilib version V0.6.33.
Data generation: Wed Mar 25 22:43:59 2020. Site generation: Sun Jan 31 12:44:45 2021

	Serveur d'exploration Chloroquine
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration Chloroquine

Antiplasmodial phenolic compounds from Piptadenia pervillei.

Antiplasmodial phenolic compounds from Piptadenia pervillei.

Source :

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri