CardioCovidV1, Main, Corpus, bibRecord, 000068

Circulating Markers of Angiogenesis and Endotheliopathy in COVID-19.

Identifieur interne : 000068 ( Main/Corpus ); précédent : 000067; suivant : 000069

Circulating Markers of Angiogenesis and Endotheliopathy in COVID-19.

Auteurs : Matthew Meizlish ; Alexander Pine ; George Goshua ; C-Hong Chang ; Hanming Zhang ; Jason Bishai ; Parveen Bahel ; Amisha Patel ; Rana Gbyli ; Jennifer Kwan ; Christina Price ; Charles Dela Cruz ; Stephanie Halene ; David Van Dijk ; John Hwa ; Alfred I. Lee ; Hyung J. Chun

Source :

medRxiv : the preprint server for health sciences ; 2020.

RBID : pubmed:32637968

Abstract

Despite over 9.3 million infected and 479,000 deaths, the pathophysiological factors that determine the wide spectrum of clinical outcomes in COVID-19 remain inadequately defined. Importantly, patients with underlying cardiovascular disease have been found to have worse clinical outcomes,1 and autopsy findings of endotheliopathy as well as angiogenesis in COVID-19 have accumulated.2,3 Nonetheless, circulating vascular markers associated with disease severity and mortality have not been reliably established. To address this limitation and better understand COVID-19 pathogenesis, we report plasma profiling of factors related to the vascular system from a series of patients admitted to Yale-New Haven Hospital with confirmed diagnosis of COVID-19 via PCR, which demonstrate significant increase in markers of angiogenesis and endotheliopathy in patients hospitalized with COVID-19.

DOI: 10.1101/2020.06.29.20140376
PubMed: 32637968
PubMed Central: PMC7340194

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pubmed:32637968

Le document en format XML

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<author><name sortKey="Goshua, George" sort="Goshua, George" uniqKey="Goshua G" first="George" last="Goshua">George Goshua</name>
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Circulating Markers of Angiogenesis and Endotheliopathy in COVID-19.

Circulating Markers of Angiogenesis and Endotheliopathy in COVID-19.

Source :

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