Serveur d'exploration Covid et maladies cardiovasculaires

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COVID-19 and the Heart and Vasculature: Novel Approaches to Reduce Virus-Induced Inflammation in Patients With Cardiovascular Disease.

Identifieur interne : 000030 ( Main/Corpus ); précédent : 000029; suivant : 000031

COVID-19 and the Heart and Vasculature: Novel Approaches to Reduce Virus-Induced Inflammation in Patients With Cardiovascular Disease.

Auteurs : Bernard S. Kadosh ; Michael S. Garshick ; Juan Gaztanaga ; Kathryn J. Moore ; Jonathan D. Newman ; Michael Pillinger ; Ravichandran Ramasamy ; Harmony R. Reynolds ; Binita Shah ; Judith Hochman ; Glenn I. Fishman ; Stuart D. Katz

Source :

RBID : pubmed:32687400

Abstract

The coronavirus disease 2019 (COVID-19) pandemic presents an unprecedented challenge and opportunity for translational investigators to rapidly develop safe and effective therapeutic interventions. Greater risk of severe disease in COVID-19 patients with comorbid diabetes mellitus, obesity, and heart disease may be attributable to synergistic activation of vascular inflammation pathways associated with both COVID-19 and cardiometabolic disease. This mechanistic link provides a scientific framework for translational studies of drugs developed for treatment of cardiometabolic disease as novel therapeutic interventions to mitigate inflammation and improve outcomes in patients with COVID-19.

DOI: 10.1161/ATVBAHA.120.314513
PubMed: 32687400

Links to Exploration step

pubmed:32687400

Le document en format XML

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