AutomedicationFrancoV1, Main, Exploration, bibRecord, 000753

The influence of progression of atrial fibrillation on quality of life: a report from the Euro Heart Survey.

Identifieur interne : 000753 ( Main/Exploration ); précédent : 000752; suivant : 000754

The influence of progression of atrial fibrillation on quality of life: a report from the Euro Heart Survey.

Auteurs : Elton A M P. Dudink [Pays-Bas] ; Ömer Erküner [Pays-Bas] ; Jenny Berg [Suède] ; Robby Nieuwlaat [Canada] ; Cees B. De Vos [Pays-Bas] ; Bob Weijs [Pays-Bas] ; Alessandro Capucci [Italie] ; A John Camm [Royaume-Uni] ; Günter Breithardt [Allemagne] ; Jean-Yves Le Heuzey [France] ; Justin G L M. Luermans [Pays-Bas] ; Harry J G M. Crijns [Pays-Bas]

Source :

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology [ 1532-2092 ] ; 2018.

RBID : pubmed:29016989

Descripteurs français

KwdFr :
- Accident vasculaire cérébral (psychologie), Accident vasculaire cérébral (étiologie), Adulte d'âge moyen (MeSH), Appréciation des risques (MeSH), Défaillance cardiaque (psychologie), Défaillance cardiaque (étiologie), Défibrillateurs implantables (psychologie), Défibrillateurs implantables (statistiques et données numériques), Effets indésirables à long terme (psychologie), Effets indésirables à long terme (étiologie), Enquêtes de santé (MeSH), Europe (épidémiologie), Facteurs de risque (MeSH), Facteurs âges (MeSH), Femelle (MeSH), Fibrillation auriculaire (physiopathologie), Fibrillation auriculaire (psychologie), Fibrillation auriculaire (thérapie), Fibrillation auriculaire (épidémiologie), Humains (MeSH), Mâle (MeSH), Qualité de vie (MeSH), Sujet âgé (MeSH), Évolution de la maladie (MeSH).
MESH :
- physiopathologie : Fibrillation auriculaire.
- psychologie : Accident vasculaire cérébral, Défaillance cardiaque, Défibrillateurs implantables, Effets indésirables à long terme, Fibrillation auriculaire.
- statistiques et données numériques : Défibrillateurs implantables.
- thérapie : Fibrillation auriculaire.
- épidémiologie : Europe, Fibrillation auriculaire.
- étiologie : Accident vasculaire cérébral, Défaillance cardiaque, Effets indésirables à long terme.
- Adulte d'âge moyen, Appréciation des risques, Enquêtes de santé, Facteurs de risque, Facteurs âges, Femelle, Humains, Mâle, Qualité de vie, Sujet âgé, Évolution de la maladie.

English descriptors

KwdEn :
- Age Factors (MeSH), Aged (MeSH), Atrial Fibrillation (epidemiology), Atrial Fibrillation (physiopathology), Atrial Fibrillation (psychology), Atrial Fibrillation (therapy), Defibrillators, Implantable (psychology), Defibrillators, Implantable (statistics & numerical data), Disease Progression (MeSH), Europe (epidemiology), Female (MeSH), Health Surveys (MeSH), Heart Failure (etiology), Heart Failure (psychology), Humans (MeSH), Long Term Adverse Effects (etiology), Long Term Adverse Effects (psychology), Male (MeSH), Middle Aged (MeSH), Quality of Life (MeSH), Risk Assessment (MeSH), Risk Factors (MeSH), Stroke (etiology), Stroke (psychology).
MESH :
- geographic , epidemiology : Europe.
- epidemiology : Atrial Fibrillation.
- etiology : Heart Failure, Long Term Adverse Effects, Stroke.
- physiopathology : Atrial Fibrillation.
- psychology : Atrial Fibrillation, Defibrillators, Implantable, Heart Failure, Long Term Adverse Effects, Stroke.
- statistics & numerical data : Defibrillators, Implantable.
- therapy : Atrial Fibrillation.
- Age Factors, Aged, Disease Progression, Female, Health Surveys, Humans, Male, Middle Aged, Quality of Life, Risk Assessment, Risk Factors.

Abstract

Aims

Progression of atrial fibrillation (AF) from paroxysmal to persistent forms is an active field of research. The influence of AF progression on health related quality of life (HRQoL) is currently unknown. We aimed to assess the influence of AF progression on HRQoL, and whether this association is mediated through symptoms, treatment, and major adverse events.

Methods and results

In the Euro Heart Survey, 967 patients were included with paroxysmal AF who filled out EuroQoL-5D at baseline and at 1 year follow-up. Those who progressed (n = 132, 13.6%) developed more problems during follow-up than those who did not, on all EuroQoL-5D domains (increase in problems on mobility 20.5% vs. 11.4%; self-care 12.9% vs. 6.2%; usual activities 23.5% vs. 14.0%; pain/discomfort 20.5% vs. 13.7%; and anxiety/depression 22.7% vs. 15.7%; all P < 0.05), leading to a decrease in utility [baseline 0.744 ± 0.26, follow-up 0.674 ± 0.36; difference -0.07 (95% CI [-0.126,-0.013], P = 0.02)]. Multivariate analysis showed that the effect of progression on utility is mediated by a large effect of adverse events [stroke (-0.27 (95% CI [-0.43,-0.11]); P = 0.001], heart failure [-0.12 (95% CI [-0.20,-0.05]); P = 0.001], malignancy (-0.31 (95% CI [-0.56,-0.05]); P = 0.02] or implantation of an implantable cardiac defibrillator [-0.12 (95% CI [-0.23,-0.02]); P = 0.03)], as well as symptomatic AF [-0.04 (95% CI [-0.08,-0.01]); P = 0.008].

Conclusion

AF progression is associated with a decrease in HRQoL. However, multivariate analysis revealed that AF progression itself does not have a negative effect on HRQoL, but that this effect can be attributed to a minor effect of the associated symptoms and a major effect of associated adverse events.

DOI: 10.1093/europace/eux217
PubMed: 29016989

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000A23
to stream Main, to step Curation: 000A23

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The influence of progression of atrial fibrillation on quality of life: a report from the Euro Heart Survey.</title>
<author><name sortKey="Dudink, Elton A M P" sort="Dudink, Elton A M P" uniqKey="Dudink E" first="Elton A M P" last="Dudink">Elton A M P. Dudink</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht, the Netherlands.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht</wicri:regionArea>
<wicri:noRegion>6229 HX Maastricht</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Erkuner, Omer" sort="Erkuner, Omer" uniqKey="Erkuner O" first="Ömer" last="Erküner">Ömer Erküner</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht, the Netherlands.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht</wicri:regionArea>
<wicri:noRegion>6229 HX Maastricht</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Berg, Jenny" sort="Berg, Jenny" uniqKey="Berg J" first="Jenny" last="Berg">Jenny Berg</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Learning, Informatics, Management and Ethics, Health Outcomes and Economic Evaluation Research Group, Karolinska Institutet, Tomtebodavägen 18 A, 171 77 Stockholm, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Learning, Informatics, Management and Ethics, Health Outcomes and Economic Evaluation Research Group, Karolinska Institutet, Tomtebodavägen 18 A, 171 77 Stockholm</wicri:regionArea>
<wicri:noRegion>171 77 Stockholm</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Nieuwlaat, Robby" sort="Nieuwlaat, Robby" uniqKey="Nieuwlaat R" first="Robby" last="Nieuwlaat">Robby Nieuwlaat</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St W, Hamilton, ON L8N 3Z5, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St W, Hamilton, ON L8N 3Z5</wicri:regionArea>
<orgName type="university">Université McMaster</orgName>
<placeName><settlement type="city">Hamilton (Ontario)</settlement>
<region type="state">Ontario</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="De Vos, Cees B" sort="De Vos, Cees B" uniqKey="De Vos C" first="Cees B" last="De Vos">Cees B. De Vos</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht, the Netherlands.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht</wicri:regionArea>
<wicri:noRegion>6229 HX Maastricht</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Weijs, Bob" sort="Weijs, Bob" uniqKey="Weijs B" first="Bob" last="Weijs">Bob Weijs</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht, the Netherlands.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht</wicri:regionArea>
<wicri:noRegion>6229 HX Maastricht</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Capucci, Alessandro" sort="Capucci, Alessandro" uniqKey="Capucci A" first="Alessandro" last="Capucci">Alessandro Capucci</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Cardiology, Marche Polytechnic University of Ancona, Via Conca 71, 60126 Ancona, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Cardiology, Marche Polytechnic University of Ancona, Via Conca 71, 60126 Ancona</wicri:regionArea>
<wicri:noRegion>60126 Ancona</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Camm, A John" sort="Camm, A John" uniqKey="Camm A" first="A John" last="Camm">A John Camm</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Cardiology, Molecular and Clinical Sciences Research Institute, Cardiology Clinical Academic Group, St George's University of London, and St George's Hospital, University of London, Cranmer Terrace, London SW17 0RE, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Cardiology, Molecular and Clinical Sciences Research Institute, Cardiology Clinical Academic Group, St George's University of London, and St George's Hospital, University of London, Cranmer Terrace, London SW17 0RE</wicri:regionArea>
<orgName type="university">Université de Londres</orgName>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Breithardt, Gunter" sort="Breithardt, Gunter" uniqKey="Breithardt G" first="Günter" last="Breithardt">Günter Breithardt</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Cardiology and Angiology, University Hospital Münster, Albert-Schweitzer-Campus 1, 48149 Münster, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Cardiology and Angiology, University Hospital Münster, Albert-Schweitzer-Campus 1, 48149 Münster</wicri:regionArea>
<placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region>
<region type="district" nuts="2">District de Münster</region>
<settlement type="city">Münster</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Le Heuzey, Jean Yves" sort="Le Heuzey, Jean Yves" uniqKey="Le Heuzey J" first="Jean-Yves" last="Le Heuzey">Jean-Yves Le Heuzey</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Cardiology, Hôpital Européen Georges Pompidou, Université Paris Descartes, 20 Rue Leblanc, 75015 Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Cardiology, Hôpital Européen Georges Pompidou, Université Paris Descartes, 20 Rue Leblanc, 75015 Paris</wicri:regionArea>
<placeName><region type="region" nuts="2">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
<orgName type="university">Université Paris-Descartes</orgName>
</affiliation>
</author>
<author><name sortKey="Luermans, Justin G L M" sort="Luermans, Justin G L M" uniqKey="Luermans J" first="Justin G L M" last="Luermans">Justin G L M. Luermans</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht, the Netherlands.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht</wicri:regionArea>
<wicri:noRegion>6229 HX Maastricht</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Crijns, Harry J G M" sort="Crijns, Harry J G M" uniqKey="Crijns H" first="Harry J G M" last="Crijns">Harry J G M. Crijns</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht, the Netherlands.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht</wicri:regionArea>
<wicri:noRegion>6229 HX Maastricht</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2018">2018</date>
<idno type="RBID">pubmed:29016989</idno>
<idno type="pmid">29016989</idno>
<idno type="doi">10.1093/europace/eux217</idno>
<idno type="wicri:Area/Main/Corpus">000A23</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000A23</idno>
<idno type="wicri:Area/Main/Curation">000A23</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000A23</idno>
<idno type="wicri:Area/Main/Exploration">000A23</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">The influence of progression of atrial fibrillation on quality of life: a report from the Euro Heart Survey.</title>
<author><name sortKey="Dudink, Elton A M P" sort="Dudink, Elton A M P" uniqKey="Dudink E" first="Elton A M P" last="Dudink">Elton A M P. Dudink</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht, the Netherlands.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht</wicri:regionArea>
<wicri:noRegion>6229 HX Maastricht</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Erkuner, Omer" sort="Erkuner, Omer" uniqKey="Erkuner O" first="Ömer" last="Erküner">Ömer Erküner</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht, the Netherlands.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht</wicri:regionArea>
<wicri:noRegion>6229 HX Maastricht</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Berg, Jenny" sort="Berg, Jenny" uniqKey="Berg J" first="Jenny" last="Berg">Jenny Berg</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Learning, Informatics, Management and Ethics, Health Outcomes and Economic Evaluation Research Group, Karolinska Institutet, Tomtebodavägen 18 A, 171 77 Stockholm, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Learning, Informatics, Management and Ethics, Health Outcomes and Economic Evaluation Research Group, Karolinska Institutet, Tomtebodavägen 18 A, 171 77 Stockholm</wicri:regionArea>
<wicri:noRegion>171 77 Stockholm</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Nieuwlaat, Robby" sort="Nieuwlaat, Robby" uniqKey="Nieuwlaat R" first="Robby" last="Nieuwlaat">Robby Nieuwlaat</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St W, Hamilton, ON L8N 3Z5, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St W, Hamilton, ON L8N 3Z5</wicri:regionArea>
<orgName type="university">Université McMaster</orgName>
<placeName><settlement type="city">Hamilton (Ontario)</settlement>
<region type="state">Ontario</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="De Vos, Cees B" sort="De Vos, Cees B" uniqKey="De Vos C" first="Cees B" last="De Vos">Cees B. De Vos</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht, the Netherlands.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht</wicri:regionArea>
<wicri:noRegion>6229 HX Maastricht</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Weijs, Bob" sort="Weijs, Bob" uniqKey="Weijs B" first="Bob" last="Weijs">Bob Weijs</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht, the Netherlands.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht</wicri:regionArea>
<wicri:noRegion>6229 HX Maastricht</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Capucci, Alessandro" sort="Capucci, Alessandro" uniqKey="Capucci A" first="Alessandro" last="Capucci">Alessandro Capucci</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Cardiology, Marche Polytechnic University of Ancona, Via Conca 71, 60126 Ancona, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Cardiology, Marche Polytechnic University of Ancona, Via Conca 71, 60126 Ancona</wicri:regionArea>
<wicri:noRegion>60126 Ancona</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Camm, A John" sort="Camm, A John" uniqKey="Camm A" first="A John" last="Camm">A John Camm</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Cardiology, Molecular and Clinical Sciences Research Institute, Cardiology Clinical Academic Group, St George's University of London, and St George's Hospital, University of London, Cranmer Terrace, London SW17 0RE, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Cardiology, Molecular and Clinical Sciences Research Institute, Cardiology Clinical Academic Group, St George's University of London, and St George's Hospital, University of London, Cranmer Terrace, London SW17 0RE</wicri:regionArea>
<orgName type="university">Université de Londres</orgName>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Breithardt, Gunter" sort="Breithardt, Gunter" uniqKey="Breithardt G" first="Günter" last="Breithardt">Günter Breithardt</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Cardiology and Angiology, University Hospital Münster, Albert-Schweitzer-Campus 1, 48149 Münster, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Cardiology and Angiology, University Hospital Münster, Albert-Schweitzer-Campus 1, 48149 Münster</wicri:regionArea>
<placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region>
<region type="district" nuts="2">District de Münster</region>
<settlement type="city">Münster</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Le Heuzey, Jean Yves" sort="Le Heuzey, Jean Yves" uniqKey="Le Heuzey J" first="Jean-Yves" last="Le Heuzey">Jean-Yves Le Heuzey</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Cardiology, Hôpital Européen Georges Pompidou, Université Paris Descartes, 20 Rue Leblanc, 75015 Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Cardiology, Hôpital Européen Georges Pompidou, Université Paris Descartes, 20 Rue Leblanc, 75015 Paris</wicri:regionArea>
<placeName><region type="region" nuts="2">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
<orgName type="university">Université Paris-Descartes</orgName>
</affiliation>
</author>
<author><name sortKey="Luermans, Justin G L M" sort="Luermans, Justin G L M" uniqKey="Luermans J" first="Justin G L M" last="Luermans">Justin G L M. Luermans</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht, the Netherlands.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht</wicri:regionArea>
<wicri:noRegion>6229 HX Maastricht</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Crijns, Harry J G M" sort="Crijns, Harry J G M" uniqKey="Crijns H" first="Harry J G M" last="Crijns">Harry J G M. Crijns</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht, the Netherlands.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht</wicri:regionArea>
<wicri:noRegion>6229 HX Maastricht</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology</title>
<idno type="eISSN">1532-2092</idno>
<imprint><date when="2018" type="published">2018</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Age Factors (MeSH)</term>
<term>Aged (MeSH)</term>
<term>Atrial Fibrillation (epidemiology)</term>
<term>Atrial Fibrillation (physiopathology)</term>
<term>Atrial Fibrillation (psychology)</term>
<term>Atrial Fibrillation (therapy)</term>
<term>Defibrillators, Implantable (psychology)</term>
<term>Defibrillators, Implantable (statistics & numerical data)</term>
<term>Disease Progression (MeSH)</term>
<term>Europe (epidemiology)</term>
<term>Female (MeSH)</term>
<term>Health Surveys (MeSH)</term>
<term>Heart Failure (etiology)</term>
<term>Heart Failure (psychology)</term>
<term>Humans (MeSH)</term>
<term>Long Term Adverse Effects (etiology)</term>
<term>Long Term Adverse Effects (psychology)</term>
<term>Male (MeSH)</term>
<term>Middle Aged (MeSH)</term>
<term>Quality of Life (MeSH)</term>
<term>Risk Assessment (MeSH)</term>
<term>Risk Factors (MeSH)</term>
<term>Stroke (etiology)</term>
<term>Stroke (psychology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Accident vasculaire cérébral (psychologie)</term>
<term>Accident vasculaire cérébral (étiologie)</term>
<term>Adulte d'âge moyen (MeSH)</term>
<term>Appréciation des risques (MeSH)</term>
<term>Défaillance cardiaque (psychologie)</term>
<term>Défaillance cardiaque (étiologie)</term>
<term>Défibrillateurs implantables (psychologie)</term>
<term>Défibrillateurs implantables (statistiques et données numériques)</term>
<term>Effets indésirables à long terme (psychologie)</term>
<term>Effets indésirables à long terme (étiologie)</term>
<term>Enquêtes de santé (MeSH)</term>
<term>Europe (épidémiologie)</term>
<term>Facteurs de risque (MeSH)</term>
<term>Facteurs âges (MeSH)</term>
<term>Femelle (MeSH)</term>
<term>Fibrillation auriculaire (physiopathologie)</term>
<term>Fibrillation auriculaire (psychologie)</term>
<term>Fibrillation auriculaire (thérapie)</term>
<term>Fibrillation auriculaire (épidémiologie)</term>
<term>Humains (MeSH)</term>
<term>Mâle (MeSH)</term>
<term>Qualité de vie (MeSH)</term>
<term>Sujet âgé (MeSH)</term>
<term>Évolution de la maladie (MeSH)</term>
</keywords>
<keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Europe</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Atrial Fibrillation</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Heart Failure</term>
<term>Long Term Adverse Effects</term>
<term>Stroke</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Fibrillation auriculaire</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Atrial Fibrillation</term>
</keywords>
<keywords scheme="MESH" qualifier="psychologie" xml:lang="fr"><term>Accident vasculaire cérébral</term>
<term>Défaillance cardiaque</term>
<term>Défibrillateurs implantables</term>
<term>Effets indésirables à long terme</term>
<term>Fibrillation auriculaire</term>
</keywords>
<keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Atrial Fibrillation</term>
<term>Defibrillators, Implantable</term>
<term>Heart Failure</term>
<term>Long Term Adverse Effects</term>
<term>Stroke</term>
</keywords>
<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Defibrillators, Implantable</term>
</keywords>
<keywords scheme="MESH" qualifier="statistiques et données numériques" xml:lang="fr"><term>Défibrillateurs implantables</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Atrial Fibrillation</term>
</keywords>
<keywords scheme="MESH" qualifier="thérapie" xml:lang="fr"><term>Fibrillation auriculaire</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Europe</term>
<term>Fibrillation auriculaire</term>
</keywords>
<keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Accident vasculaire cérébral</term>
<term>Défaillance cardiaque</term>
<term>Effets indésirables à long terme</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Age Factors</term>
<term>Aged</term>
<term>Disease Progression</term>
<term>Female</term>
<term>Health Surveys</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Quality of Life</term>
<term>Risk Assessment</term>
<term>Risk Factors</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Appréciation des risques</term>
<term>Enquêtes de santé</term>
<term>Facteurs de risque</term>
<term>Facteurs âges</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Qualité de vie</term>
<term>Sujet âgé</term>
<term>Évolution de la maladie</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p><b>Aims</b>
</p>
<p>Progression of atrial fibrillation (AF) from paroxysmal to persistent forms is an active field of research. The influence of AF progression on health related quality of life (HRQoL) is currently unknown. We aimed to assess the influence of AF progression on HRQoL, and whether this association is mediated through symptoms, treatment, and major adverse events.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>Methods and results</b>
</p>
<p>In the Euro Heart Survey, 967 patients were included with paroxysmal AF who filled out EuroQoL-5D at baseline and at 1 year follow-up. Those who progressed (n = 132, 13.6%) developed more problems during follow-up than those who did not, on all EuroQoL-5D domains (increase in problems on mobility 20.5% vs. 11.4%; self-care 12.9% vs. 6.2%; usual activities 23.5% vs. 14.0%; pain/discomfort 20.5% vs. 13.7%; and anxiety/depression 22.7% vs. 15.7%; all P < 0.05), leading to a decrease in utility [baseline 0.744 ± 0.26, follow-up 0.674 ± 0.36; difference -0.07 (95% CI [-0.126,-0.013], P = 0.02)]. Multivariate analysis showed that the effect of progression on utility is mediated by a large effect of adverse events [stroke (-0.27 (95% CI [-0.43,-0.11]); P = 0.001], heart failure [-0.12 (95% CI [-0.20,-0.05]); P = 0.001], malignancy (-0.31 (95% CI [-0.56,-0.05]); P = 0.02] or implantation of an implantable cardiac defibrillator [-0.12 (95% CI [-0.23,-0.02]); P = 0.03)], as well as symptomatic AF [-0.04 (95% CI [-0.08,-0.01]); P = 0.008].</p>
</div>
<div type="abstract" xml:lang="en"><p><b>Conclusion</b>
</p>
<p>AF progression is associated with a decrease in HRQoL. However, multivariate analysis revealed that AF progression itself does not have a negative effect on HRQoL, but that this effect can be attributed to a minor effect of the associated symptoms and a major effect of associated adverse events.</p>
</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">29016989</PMID>
<DateCompleted><Year>2019</Year>
<Month>03</Month>
<Day>01</Day>
</DateCompleted>
<DateRevised><Year>2019</Year>
<Month>03</Month>
<Day>01</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1532-2092</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>20</Volume>
<Issue>6</Issue>
<PubDate><Year>2018</Year>
<Month>06</Month>
<Day>01</Day>
</PubDate>
</JournalIssue>
<Title>Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology</Title>
<ISOAbbreviation>Europace</ISOAbbreviation>
</Journal>
<ArticleTitle>The influence of progression of atrial fibrillation on quality of life: a report from the Euro Heart Survey.</ArticleTitle>
<Pagination><MedlinePgn>929-934</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1093/europace/eux217</ELocationID>
<Abstract><AbstractText Label="Aims">Progression of atrial fibrillation (AF) from paroxysmal to persistent forms is an active field of research. The influence of AF progression on health related quality of life (HRQoL) is currently unknown. We aimed to assess the influence of AF progression on HRQoL, and whether this association is mediated through symptoms, treatment, and major adverse events.</AbstractText>
<AbstractText Label="Methods and results">In the Euro Heart Survey, 967 patients were included with paroxysmal AF who filled out EuroQoL-5D at baseline and at 1 year follow-up. Those who progressed (n = 132, 13.6%) developed more problems during follow-up than those who did not, on all EuroQoL-5D domains (increase in problems on mobility 20.5% vs. 11.4%; self-care 12.9% vs. 6.2%; usual activities 23.5% vs. 14.0%; pain/discomfort 20.5% vs. 13.7%; and anxiety/depression 22.7% vs. 15.7%; all P < 0.05), leading to a decrease in utility [baseline 0.744 ± 0.26, follow-up 0.674 ± 0.36; difference -0.07 (95% CI [-0.126,-0.013], P = 0.02)]. Multivariate analysis showed that the effect of progression on utility is mediated by a large effect of adverse events [stroke (-0.27 (95% CI [-0.43,-0.11]); P = 0.001], heart failure [-0.12 (95% CI [-0.20,-0.05]); P = 0.001], malignancy (-0.31 (95% CI [-0.56,-0.05]); P = 0.02] or implantation of an implantable cardiac defibrillator [-0.12 (95% CI [-0.23,-0.02]); P = 0.03)], as well as symptomatic AF [-0.04 (95% CI [-0.08,-0.01]); P = 0.008].</AbstractText>
<AbstractText Label="Conclusion">AF progression is associated with a decrease in HRQoL. However, multivariate analysis revealed that AF progression itself does not have a negative effect on HRQoL, but that this effect can be attributed to a minor effect of the associated symptoms and a major effect of associated adverse events.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Dudink</LastName>
<ForeName>Elton A M P</ForeName>
<Initials>EAMP</Initials>
<AffiliationInfo><Affiliation>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht, the Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Erküner</LastName>
<ForeName>Ömer</ForeName>
<Initials>Ö</Initials>
<AffiliationInfo><Affiliation>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht, the Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Berg</LastName>
<ForeName>Jenny</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Department of Learning, Informatics, Management and Ethics, Health Outcomes and Economic Evaluation Research Group, Karolinska Institutet, Tomtebodavägen 18 A, 171 77 Stockholm, Sweden.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Nieuwlaat</LastName>
<ForeName>Robby</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St W, Hamilton, ON L8N 3Z5, Canada.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>de Vos</LastName>
<ForeName>Cees B</ForeName>
<Initials>CB</Initials>
<AffiliationInfo><Affiliation>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht, the Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Weijs</LastName>
<ForeName>Bob</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht, the Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Capucci</LastName>
<ForeName>Alessandro</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Cardiology, Marche Polytechnic University of Ancona, Via Conca 71, 60126 Ancona, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Camm</LastName>
<ForeName>A John</ForeName>
<Initials>AJ</Initials>
<AffiliationInfo><Affiliation>Department of Cardiology, Molecular and Clinical Sciences Research Institute, Cardiology Clinical Academic Group, St George's University of London, and St George's Hospital, University of London, Cranmer Terrace, London SW17 0RE, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Breithardt</LastName>
<ForeName>Günter</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Department of Cardiology and Angiology, University Hospital Münster, Albert-Schweitzer-Campus 1, 48149 Münster, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Le Heuzey</LastName>
<ForeName>Jean-Yves</ForeName>
<Initials>JY</Initials>
<AffiliationInfo><Affiliation>Department of Cardiology, Hôpital Européen Georges Pompidou, Université Paris Descartes, 20 Rue Leblanc, 75015 Paris, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Luermans</LastName>
<ForeName>Justin G L M</ForeName>
<Initials>JGLM</Initials>
<AffiliationInfo><Affiliation>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht, the Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Crijns</LastName>
<ForeName>Harry J G M</ForeName>
<Initials>HJGM</Initials>
<AffiliationInfo><Affiliation>Department of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research Institute Maastricht (CARIM), P. Debyelaan 25, 6229 HX Maastricht, the Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>England</Country>
<MedlineTA>Europace</MedlineTA>
<NlmUniqueID>100883649</NlmUniqueID>
<ISSNLinking>1099-5129</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000367" MajorTopicYN="N">Age Factors</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D001281" MajorTopicYN="Y">Atrial Fibrillation</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName>
<QualifierName UI="Q000523" MajorTopicYN="N">psychology</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D017147" MajorTopicYN="Y">Defibrillators, Implantable</DescriptorName>
<QualifierName UI="Q000523" MajorTopicYN="N">psychology</QualifierName>
<QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018450" MajorTopicYN="N">Disease Progression</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005060" MajorTopicYN="N" Type="Geographic">Europe</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006306" MajorTopicYN="N">Health Surveys</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006333" MajorTopicYN="Y">Heart Failure</DescriptorName>
<QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName>
<QualifierName UI="Q000523" MajorTopicYN="N">psychology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000069451" MajorTopicYN="N">Long Term Adverse Effects</DescriptorName>
<QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName>
<QualifierName UI="Q000523" MajorTopicYN="N">psychology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011788" MajorTopicYN="Y">Quality of Life</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018570" MajorTopicYN="N">Risk Assessment</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012307" MajorTopicYN="N">Risk Factors</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D020521" MajorTopicYN="Y">Stroke</DescriptorName>
<QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName>
<QualifierName UI="Q000523" MajorTopicYN="N">psychology</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2017</Year>
<Month>04</Month>
<Day>04</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2017</Year>
<Month>06</Month>
<Day>02</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2017</Year>
<Month>10</Month>
<Day>11</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2019</Year>
<Month>3</Month>
<Day>2</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2017</Year>
<Month>10</Month>
<Day>11</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">29016989</ArticleId>
<ArticleId IdType="pii">3979528</ArticleId>
<ArticleId IdType="doi">10.1093/europace/eux217</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>Allemagne</li>
<li>Canada</li>
<li>France</li>
<li>Italie</li>
<li>Pays-Bas</li>
<li>Royaume-Uni</li>
<li>Suède</li>
</country>
<region><li>Angleterre</li>
<li>District de Münster</li>
<li>Grand Londres</li>
<li>Ontario</li>
<li>Rhénanie-du-Nord-Westphalie</li>
<li>Île-de-France</li>
</region>
<settlement><li>Hamilton (Ontario)</li>
<li>Londres</li>
<li>Münster</li>
<li>Paris</li>
</settlement>
<orgName><li>Université McMaster</li>
<li>Université Paris-Descartes</li>
<li>Université de Londres</li>
</orgName>
</list>
<tree><country name="Pays-Bas"><noRegion><name sortKey="Dudink, Elton A M P" sort="Dudink, Elton A M P" uniqKey="Dudink E" first="Elton A M P" last="Dudink">Elton A M P. Dudink</name>
</noRegion>
<name sortKey="Crijns, Harry J G M" sort="Crijns, Harry J G M" uniqKey="Crijns H" first="Harry J G M" last="Crijns">Harry J G M. Crijns</name>
<name sortKey="De Vos, Cees B" sort="De Vos, Cees B" uniqKey="De Vos C" first="Cees B" last="De Vos">Cees B. De Vos</name>
<name sortKey="Erkuner, Omer" sort="Erkuner, Omer" uniqKey="Erkuner O" first="Ömer" last="Erküner">Ömer Erküner</name>
<name sortKey="Luermans, Justin G L M" sort="Luermans, Justin G L M" uniqKey="Luermans J" first="Justin G L M" last="Luermans">Justin G L M. Luermans</name>
<name sortKey="Weijs, Bob" sort="Weijs, Bob" uniqKey="Weijs B" first="Bob" last="Weijs">Bob Weijs</name>
</country>
<country name="Suède"><noRegion><name sortKey="Berg, Jenny" sort="Berg, Jenny" uniqKey="Berg J" first="Jenny" last="Berg">Jenny Berg</name>
</noRegion>
</country>
<country name="Canada"><region name="Ontario"><name sortKey="Nieuwlaat, Robby" sort="Nieuwlaat, Robby" uniqKey="Nieuwlaat R" first="Robby" last="Nieuwlaat">Robby Nieuwlaat</name>
</region>
</country>
<country name="Italie"><noRegion><name sortKey="Capucci, Alessandro" sort="Capucci, Alessandro" uniqKey="Capucci A" first="Alessandro" last="Capucci">Alessandro Capucci</name>
</noRegion>
</country>
<country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Camm, A John" sort="Camm, A John" uniqKey="Camm A" first="A John" last="Camm">A John Camm</name>
</region>
</country>
<country name="Allemagne"><region name="Rhénanie-du-Nord-Westphalie"><name sortKey="Breithardt, Gunter" sort="Breithardt, Gunter" uniqKey="Breithardt G" first="Günter" last="Breithardt">Günter Breithardt</name>
</region>
</country>
<country name="France"><region name="Île-de-France"><name sortKey="Le Heuzey, Jean Yves" sort="Le Heuzey, Jean Yves" uniqKey="Le Heuzey J" first="Jean-Yves" last="Le Heuzey">Jean-Yves Le Heuzey</name>
</region>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/AutomedicationFrancoV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000753 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000753 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    AutomedicationFrancoV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:29016989
   |texte=   The influence of progression of atrial fibrillation on quality of life: a report from the Euro Heart Survey.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:29016989" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a AutomedicationFrancoV1

This area was generated with Dilib version V0.6.38.
Data generation: Mon Mar 15 15:24:36 2021. Site generation: Mon Mar 15 15:32:03 2021

	Serveur d'exploration sur l'automédication dans le monde francophone
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur l'automédication dans le monde francophone

The influence of progression of atrial fibrillation on quality of life: a report from the Euro Heart Survey.

The influence of progression of atrial fibrillation on quality of life: a report from the Euro Heart Survey.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki