Perceived Health Mediates Effects of Physical Activity on Quality of Life in Patients With a Fontan Circulation.
Identifieur interne : 000511 ( Main/Corpus ); précédent : 000510; suivant : 000512Perceived Health Mediates Effects of Physical Activity on Quality of Life in Patients With a Fontan Circulation.
Auteurs : Christina E. Holbein ; Gruschen R. Veldtman ; Philip Moons ; Adrienne H. Kovacs ; Koen Luyckx ; Silke Apers ; Shanti Chidambarathanu ; Alexandra Soufi ; Katrine Eriksen ; Jamie L. Jackson ; Junko Enomoto ; Susan M. Fernandes ; Bengt Johansson ; Luis Alday ; Mikael Dellborg ; Malin Berghammer ; Samuel Menahem ; Maryanne Caruana ; Shelby Kutty ; Andrew S. Mackie ; Corina Thomet ; Werner Budts ; Kamila White ; Maayke A. Sluman ; Edward Callus ; Stephen C. Cook ; Paul Khairy ; Ari CedarsSource :
- The American journal of cardiology [ 1879-1913 ] ; 2019.
English descriptors
- KwdEn :
- Adult (MeSH), Cross-Sectional Studies (MeSH), Exercise (MeSH), Female (MeSH), Fontan Procedure (MeSH), Health Status (MeSH), Heart Defects, Congenital (physiopathology), Heart Defects, Congenital (psychology), Heart Defects, Congenital (surgery), Humans (MeSH), Male (MeSH), Quality of Life (MeSH), Sedentary Behavior (MeSH), Self Concept (MeSH), Self Report (MeSH), Young Adult (MeSH).
- MESH :
- physiopathology : Heart Defects, Congenital.
- psychology : Heart Defects, Congenital.
- surgery : Heart Defects, Congenital.
- Adult, Cross-Sectional Studies, Exercise, Female, Fontan Procedure, Health Status, Humans, Male, Quality of Life, Sedentary Behavior, Self Concept, Self Report, Young Adult.
Abstract
Patients with a Fontan circulation are at risk of a sedentary lifestyle. Given the direct relationship between physical activity and health, promotion of physical activity has the potential to improve outcomes, including quality of life (QOL). This study aimed to describe self-reported physical activity levels in adult Fontan patients and examine associations between physical activity, perceived health status and QOL. The sample consisted of 177 Fontan patients (Mage = 27.5 ± 7.6 years, 52% male) who reported their physical activity, perceived health status, and QOL as part of the cross-sectional Assessment of Patterns of Patient-Reported Outcomes in Adults with Congenital Heart disease - International Study. Descriptive statistics and univariate analyses of variance with planned contrasts were computed to describe physical activity characteristics. Mediation analyses tested whether perceived health status variables mediated the association between physical activity and QOL. Forty-six percent of patients were sedentary while only 40% met international physical activity guidelines. Higher physical activity was associated with younger age, lower NYHA class, higher perceived general health, and greater QOL. Patients who commuted by walking and engaged in sports reported better perceived health and QOL. Mediation analyses revealed that perceived general health but not NYHA functional class mediated the association between physical activity and QOL (αβ = 0.22, 95% confidence interval = 0.04 to 0.49). In conclusion, Fontan patients likely benefit from regular physical activity, having both higher perceived general health and functional capacity; greater perceived health status may contribute to enhanced QOL. In conclusion, these data support the pivotal role of regular physical activity for Fontan patients.
DOI: 10.1016/j.amjcard.2019.03.039
PubMed: 31030969
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Perceived Health Mediates Effects of Physical Activity on Quality of Life in Patients With a Fontan Circulation.</title><author><name sortKey="Holbein, Christina E" sort="Holbein, Christina E" uniqKey="Holbein C" first="Christina E" last="Holbein">Christina E. Holbein</name><affiliation><nlm:affiliation>Department of Child and Adolescent Psychiatry and Behavioral Sciences, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.</nlm:affiliation></affiliation></author><author><name sortKey="Veldtman, Gruschen R" sort="Veldtman, Gruschen R" uniqKey="Veldtman G" first="Gruschen R" last="Veldtman">Gruschen R. Veldtman</name><affiliation><nlm:affiliation>King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.</nlm:affiliation></affiliation></author><author><name sortKey="Moons, Philip" sort="Moons, Philip" uniqKey="Moons P" first="Philip" last="Moons">Philip Moons</name><affiliation><nlm:affiliation>KU Leuven Department of Public Health and Primary Care, KU Leuven - University of Leuven, Leuven, Belgium; Institute of Health and Care Sciences, University of Gothenburg, Gothenburg, Sweden; Department of Paediatrics and Child Health, University of Cape Town, Cape Town, South Africa.</nlm:affiliation></affiliation></author><author><name sortKey="Kovacs, Adrienne H" sort="Kovacs, Adrienne H" uniqKey="Kovacs A" first="Adrienne H" last="Kovacs">Adrienne H. Kovacs</name><affiliation><nlm:affiliation>Peter Munk Cardiac Centre, University Health Network, University of Toronto, Toronto, Canada; Knight Cardiovascular Institute, Oregon Health & Science University, Portland, Oregon.</nlm:affiliation></affiliation></author><author><name sortKey="Luyckx, Koen" sort="Luyckx, Koen" uniqKey="Luyckx K" first="Koen" last="Luyckx">Koen Luyckx</name><affiliation><nlm:affiliation>School Psychology and Development in Context, KU Leuven - University of Leuven, Leuven, Belgium; UNIBS, University of the Free State Bloemfontein, Bloemfontein, South Africa.</nlm:affiliation></affiliation></author><author><name sortKey="Apers, Silke" sort="Apers, Silke" uniqKey="Apers S" first="Silke" last="Apers">Silke Apers</name><affiliation><nlm:affiliation>KU Leuven Department of Public Health and Primary Care, KU Leuven - University of Leuven, Leuven, Belgium.</nlm:affiliation></affiliation></author><author><name sortKey="Chidambarathanu, Shanti" sort="Chidambarathanu, Shanti" uniqKey="Chidambarathanu S" first="Shanti" last="Chidambarathanu">Shanti Chidambarathanu</name><affiliation><nlm:affiliation>Pediatric Cardiology, Frontier Lifeline Hospital (Dr. K. M. Cherian Heart Foundation), Chennai, India.</nlm:affiliation></affiliation></author><author><name sortKey="Soufi, Alexandra" sort="Soufi, Alexandra" uniqKey="Soufi A" first="Alexandra" last="Soufi">Alexandra Soufi</name><affiliation><nlm:affiliation>Department of Congenital Heart Disease, Louis Pradel Hospital, Hospices civils de Lyon, Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Eriksen, Katrine" sort="Eriksen, Katrine" uniqKey="Eriksen K" first="Katrine" last="Eriksen">Katrine Eriksen</name><affiliation><nlm:affiliation>Adult Congenital Heart Disease Center, Oslo University Hospital - Rikshospitalet, Oslo, Norway.</nlm:affiliation></affiliation></author><author><name sortKey="Jackson, Jamie L" sort="Jackson, Jamie L" uniqKey="Jackson J" first="Jamie L" last="Jackson">Jamie L. Jackson</name><affiliation><nlm:affiliation>Center for Biobehavioral Health, Nationwide Children's Hospital, Columbus, Ohio.</nlm:affiliation></affiliation></author><author><name sortKey="Enomoto, Junko" sort="Enomoto, Junko" uniqKey="Enomoto J" first="Junko" last="Enomoto">Junko Enomoto</name><affiliation><nlm:affiliation>Department of Adult Congenital Heart Disease, Chiba Cardiovascular Center, Chiba, Japan.</nlm:affiliation></affiliation></author><author><name sortKey="Fernandes, Susan M" sort="Fernandes, Susan M" uniqKey="Fernandes S" first="Susan M" last="Fernandes">Susan M. Fernandes</name><affiliation><nlm:affiliation>Stanford University School of Medicine, Department of Pediatrics and Medicine, Division of Pediatric Cardiology and Cardiovascular Medicine, Palo Alto, California.</nlm:affiliation></affiliation></author><author><name sortKey="Johansson, Bengt" sort="Johansson, Bengt" uniqKey="Johansson B" first="Bengt" last="Johansson">Bengt Johansson</name><affiliation><nlm:affiliation>Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Alday, Luis" sort="Alday, Luis" uniqKey="Alday L" first="Luis" last="Alday">Luis Alday</name><affiliation><nlm:affiliation>Division of Cardiology, Hospital de Niños, Córdoba, Argentina.</nlm:affiliation></affiliation></author><author><name sortKey="Dellborg, Mikael" sort="Dellborg, Mikael" uniqKey="Dellborg M" first="Mikael" last="Dellborg">Mikael Dellborg</name><affiliation><nlm:affiliation>Adult Congenital Heart Unit, Sahlgrenska University Hospital/Östra, Gothenburg, Sweden; Institute of Medicine, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Berghammer, Malin" sort="Berghammer, Malin" uniqKey="Berghammer M" first="Malin" last="Berghammer">Malin Berghammer</name><affiliation><nlm:affiliation>Institute of Health and Care Sciences, University of Gothenburg, Gothenburg, Sweden; Department of Health Sciences, University West, Trollhättan, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Menahem, Samuel" sort="Menahem, Samuel" uniqKey="Menahem S" first="Samuel" last="Menahem">Samuel Menahem</name><affiliation><nlm:affiliation>Monash Heart, Monash Medical Centre, Monash University, Melbourne, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Caruana, Maryanne" sort="Caruana, Maryanne" uniqKey="Caruana M" first="Maryanne" last="Caruana">Maryanne Caruana</name><affiliation><nlm:affiliation>Department of Cardiology, Mater Dei Hospital, Birkirkara, Malta.</nlm:affiliation></affiliation></author><author><name sortKey="Kutty, Shelby" sort="Kutty, Shelby" uniqKey="Kutty S" first="Shelby" last="Kutty">Shelby Kutty</name><affiliation><nlm:affiliation>Adult Congenital Heart Disease Center, University of Nebraska Medical Center/ Children's Hospital and Medical Center, Omaha, Nebraska.</nlm:affiliation></affiliation></author><author><name sortKey="Mackie, Andrew S" sort="Mackie, Andrew S" uniqKey="Mackie A" first="Andrew S" last="Mackie">Andrew S. Mackie</name><affiliation><nlm:affiliation>Division of Cardiology, Stollery Children's Hospital, University of Alberta, Edmonton, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Thomet, Corina" sort="Thomet, Corina" uniqKey="Thomet C" first="Corina" last="Thomet">Corina Thomet</name><affiliation><nlm:affiliation>Center for Congenital Heart Disease, Department of Cardiology, Inselspital - Bern University Hospital, University of Bern, Bern, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Budts, Werner" sort="Budts, Werner" uniqKey="Budts W" first="Werner" last="Budts">Werner Budts</name><affiliation><nlm:affiliation>Division of Congenital and Structural Cardiology, University Hospitals Leuven, Leuven, Belgium; KU Leuven Department of Cardiovascular Sciences, KU Leuven - University of Leuven, Leuven, Belgium.</nlm:affiliation></affiliation></author><author><name sortKey="White, Kamila" sort="White, Kamila" uniqKey="White K" first="Kamila" last="White">Kamila White</name><affiliation><nlm:affiliation>Adult Congenital Heart Disease Center, Washington University and Barnes Jewish Heart & Vascular Center, University of Missouri, Saint Louis, Missouri.</nlm:affiliation></affiliation></author><author><name sortKey="Sluman, Maayke A" sort="Sluman, Maayke A" uniqKey="Sluman M" first="Maayke A" last="Sluman">Maayke A. Sluman</name><affiliation><nlm:affiliation>Department of Cardiology, Academic Medical Center, Amsterdam, the Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Callus, Edward" sort="Callus, Edward" uniqKey="Callus E" first="Edward" last="Callus">Edward Callus</name><affiliation><nlm:affiliation>Clinical Psychology Service, IRCCS Policlinico San Donato, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Cook, Stephen C" sort="Cook, Stephen C" uniqKey="Cook S" first="Stephen C" last="Cook">Stephen C. Cook</name><affiliation><nlm:affiliation>Adult Congenital Heart Disease Center, Helen DeVos Children's Hospital, Grand Rapids, Michigan.</nlm:affiliation></affiliation></author><author><name sortKey="Khairy, Paul" sort="Khairy, Paul" uniqKey="Khairy P" first="Paul" last="Khairy">Paul Khairy</name><affiliation><nlm:affiliation>Adult Congenital Heart Center, Montreal Heart Institute, Université de Montréal, Montreal, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Cedars, Ari" sort="Cedars, Ari" uniqKey="Cedars A" first="Ari" last="Cedars">Ari Cedars</name><affiliation><nlm:affiliation>The University of Texas Southwestern Medical Center, Dallas, Texas. Electronic address: ari.cedars@utsouthwestern.edu.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2019">2019</date><idno type="RBID">pubmed:31030969</idno><idno type="pmid">31030969</idno><idno type="doi">10.1016/j.amjcard.2019.03.039</idno><idno type="wicri:Area/Main/Corpus">000511</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000511</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Perceived Health Mediates Effects of Physical Activity on Quality of Life in Patients With a Fontan Circulation.</title><author><name sortKey="Holbein, Christina E" sort="Holbein, Christina E" uniqKey="Holbein C" first="Christina E" last="Holbein">Christina E. Holbein</name><affiliation><nlm:affiliation>Department of Child and Adolescent Psychiatry and Behavioral Sciences, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.</nlm:affiliation></affiliation></author><author><name sortKey="Veldtman, Gruschen R" sort="Veldtman, Gruschen R" uniqKey="Veldtman G" first="Gruschen R" last="Veldtman">Gruschen R. Veldtman</name><affiliation><nlm:affiliation>King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.</nlm:affiliation></affiliation></author><author><name sortKey="Moons, Philip" sort="Moons, Philip" uniqKey="Moons P" first="Philip" last="Moons">Philip Moons</name><affiliation><nlm:affiliation>KU Leuven Department of Public Health and Primary Care, KU Leuven - University of Leuven, Leuven, Belgium; Institute of Health and Care Sciences, University of Gothenburg, Gothenburg, Sweden; Department of Paediatrics and Child Health, University of Cape Town, Cape Town, South Africa.</nlm:affiliation></affiliation></author><author><name sortKey="Kovacs, Adrienne H" sort="Kovacs, Adrienne H" uniqKey="Kovacs A" first="Adrienne H" last="Kovacs">Adrienne H. Kovacs</name><affiliation><nlm:affiliation>Peter Munk Cardiac Centre, University Health Network, University of Toronto, Toronto, Canada; Knight Cardiovascular Institute, Oregon Health & Science University, Portland, Oregon.</nlm:affiliation></affiliation></author><author><name sortKey="Luyckx, Koen" sort="Luyckx, Koen" uniqKey="Luyckx K" first="Koen" last="Luyckx">Koen Luyckx</name><affiliation><nlm:affiliation>School Psychology and Development in Context, KU Leuven - University of Leuven, Leuven, Belgium; UNIBS, University of the Free State Bloemfontein, Bloemfontein, South Africa.</nlm:affiliation></affiliation></author><author><name sortKey="Apers, Silke" sort="Apers, Silke" uniqKey="Apers S" first="Silke" last="Apers">Silke Apers</name><affiliation><nlm:affiliation>KU Leuven Department of Public Health and Primary Care, KU Leuven - University of Leuven, Leuven, Belgium.</nlm:affiliation></affiliation></author><author><name sortKey="Chidambarathanu, Shanti" sort="Chidambarathanu, Shanti" uniqKey="Chidambarathanu S" first="Shanti" last="Chidambarathanu">Shanti Chidambarathanu</name><affiliation><nlm:affiliation>Pediatric Cardiology, Frontier Lifeline Hospital (Dr. K. M. Cherian Heart Foundation), Chennai, India.</nlm:affiliation></affiliation></author><author><name sortKey="Soufi, Alexandra" sort="Soufi, Alexandra" uniqKey="Soufi A" first="Alexandra" last="Soufi">Alexandra Soufi</name><affiliation><nlm:affiliation>Department of Congenital Heart Disease, Louis Pradel Hospital, Hospices civils de Lyon, Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Eriksen, Katrine" sort="Eriksen, Katrine" uniqKey="Eriksen K" first="Katrine" last="Eriksen">Katrine Eriksen</name><affiliation><nlm:affiliation>Adult Congenital Heart Disease Center, Oslo University Hospital - Rikshospitalet, Oslo, Norway.</nlm:affiliation></affiliation></author><author><name sortKey="Jackson, Jamie L" sort="Jackson, Jamie L" uniqKey="Jackson J" first="Jamie L" last="Jackson">Jamie L. Jackson</name><affiliation><nlm:affiliation>Center for Biobehavioral Health, Nationwide Children's Hospital, Columbus, Ohio.</nlm:affiliation></affiliation></author><author><name sortKey="Enomoto, Junko" sort="Enomoto, Junko" uniqKey="Enomoto J" first="Junko" last="Enomoto">Junko Enomoto</name><affiliation><nlm:affiliation>Department of Adult Congenital Heart Disease, Chiba Cardiovascular Center, Chiba, Japan.</nlm:affiliation></affiliation></author><author><name sortKey="Fernandes, Susan M" sort="Fernandes, Susan M" uniqKey="Fernandes S" first="Susan M" last="Fernandes">Susan M. Fernandes</name><affiliation><nlm:affiliation>Stanford University School of Medicine, Department of Pediatrics and Medicine, Division of Pediatric Cardiology and Cardiovascular Medicine, Palo Alto, California.</nlm:affiliation></affiliation></author><author><name sortKey="Johansson, Bengt" sort="Johansson, Bengt" uniqKey="Johansson B" first="Bengt" last="Johansson">Bengt Johansson</name><affiliation><nlm:affiliation>Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Alday, Luis" sort="Alday, Luis" uniqKey="Alday L" first="Luis" last="Alday">Luis Alday</name><affiliation><nlm:affiliation>Division of Cardiology, Hospital de Niños, Córdoba, Argentina.</nlm:affiliation></affiliation></author><author><name sortKey="Dellborg, Mikael" sort="Dellborg, Mikael" uniqKey="Dellborg M" first="Mikael" last="Dellborg">Mikael Dellborg</name><affiliation><nlm:affiliation>Adult Congenital Heart Unit, Sahlgrenska University Hospital/Östra, Gothenburg, Sweden; Institute of Medicine, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Berghammer, Malin" sort="Berghammer, Malin" uniqKey="Berghammer M" first="Malin" last="Berghammer">Malin Berghammer</name><affiliation><nlm:affiliation>Institute of Health and Care Sciences, University of Gothenburg, Gothenburg, Sweden; Department of Health Sciences, University West, Trollhättan, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Menahem, Samuel" sort="Menahem, Samuel" uniqKey="Menahem S" first="Samuel" last="Menahem">Samuel Menahem</name><affiliation><nlm:affiliation>Monash Heart, Monash Medical Centre, Monash University, Melbourne, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Caruana, Maryanne" sort="Caruana, Maryanne" uniqKey="Caruana M" first="Maryanne" last="Caruana">Maryanne Caruana</name><affiliation><nlm:affiliation>Department of Cardiology, Mater Dei Hospital, Birkirkara, Malta.</nlm:affiliation></affiliation></author><author><name sortKey="Kutty, Shelby" sort="Kutty, Shelby" uniqKey="Kutty S" first="Shelby" last="Kutty">Shelby Kutty</name><affiliation><nlm:affiliation>Adult Congenital Heart Disease Center, University of Nebraska Medical Center/ Children's Hospital and Medical Center, Omaha, Nebraska.</nlm:affiliation></affiliation></author><author><name sortKey="Mackie, Andrew S" sort="Mackie, Andrew S" uniqKey="Mackie A" first="Andrew S" last="Mackie">Andrew S. Mackie</name><affiliation><nlm:affiliation>Division of Cardiology, Stollery Children's Hospital, University of Alberta, Edmonton, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Thomet, Corina" sort="Thomet, Corina" uniqKey="Thomet C" first="Corina" last="Thomet">Corina Thomet</name><affiliation><nlm:affiliation>Center for Congenital Heart Disease, Department of Cardiology, Inselspital - Bern University Hospital, University of Bern, Bern, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Budts, Werner" sort="Budts, Werner" uniqKey="Budts W" first="Werner" last="Budts">Werner Budts</name><affiliation><nlm:affiliation>Division of Congenital and Structural Cardiology, University Hospitals Leuven, Leuven, Belgium; KU Leuven Department of Cardiovascular Sciences, KU Leuven - University of Leuven, Leuven, Belgium.</nlm:affiliation></affiliation></author><author><name sortKey="White, Kamila" sort="White, Kamila" uniqKey="White K" first="Kamila" last="White">Kamila White</name><affiliation><nlm:affiliation>Adult Congenital Heart Disease Center, Washington University and Barnes Jewish Heart & Vascular Center, University of Missouri, Saint Louis, Missouri.</nlm:affiliation></affiliation></author><author><name sortKey="Sluman, Maayke A" sort="Sluman, Maayke A" uniqKey="Sluman M" first="Maayke A" last="Sluman">Maayke A. Sluman</name><affiliation><nlm:affiliation>Department of Cardiology, Academic Medical Center, Amsterdam, the Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Callus, Edward" sort="Callus, Edward" uniqKey="Callus E" first="Edward" last="Callus">Edward Callus</name><affiliation><nlm:affiliation>Clinical Psychology Service, IRCCS Policlinico San Donato, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Cook, Stephen C" sort="Cook, Stephen C" uniqKey="Cook S" first="Stephen C" last="Cook">Stephen C. Cook</name><affiliation><nlm:affiliation>Adult Congenital Heart Disease Center, Helen DeVos Children's Hospital, Grand Rapids, Michigan.</nlm:affiliation></affiliation></author><author><name sortKey="Khairy, Paul" sort="Khairy, Paul" uniqKey="Khairy P" first="Paul" last="Khairy">Paul Khairy</name><affiliation><nlm:affiliation>Adult Congenital Heart Center, Montreal Heart Institute, Université de Montréal, Montreal, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Cedars, Ari" sort="Cedars, Ari" uniqKey="Cedars A" first="Ari" last="Cedars">Ari Cedars</name><affiliation><nlm:affiliation>The University of Texas Southwestern Medical Center, Dallas, Texas. Electronic address: ari.cedars@utsouthwestern.edu.</nlm:affiliation></affiliation></author></analytic><series><title level="j">The American journal of cardiology</title><idno type="eISSN">1879-1913</idno><imprint><date when="2019" type="published">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult (MeSH)</term><term>Cross-Sectional Studies (MeSH)</term><term>Exercise (MeSH)</term><term>Female (MeSH)</term><term>Fontan Procedure (MeSH)</term><term>Health Status (MeSH)</term><term>Heart Defects, Congenital (physiopathology)</term><term>Heart Defects, Congenital (psychology)</term><term>Heart Defects, Congenital (surgery)</term><term>Humans (MeSH)</term><term>Male (MeSH)</term><term>Quality of Life (MeSH)</term><term>Sedentary Behavior (MeSH)</term><term>Self Concept (MeSH)</term><term>Self Report (MeSH)</term><term>Young Adult (MeSH)</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Heart Defects, Congenital</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Heart Defects, Congenital</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Heart Defects, Congenital</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Cross-Sectional Studies</term><term>Exercise</term><term>Female</term><term>Fontan Procedure</term><term>Health Status</term><term>Humans</term><term>Male</term><term>Quality of Life</term><term>Sedentary Behavior</term><term>Self Concept</term><term>Self Report</term><term>Young Adult</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Patients with a Fontan circulation are at risk of a sedentary lifestyle. Given the direct relationship between physical activity and health, promotion of physical activity has the potential to improve outcomes, including quality of life (QOL). This study aimed to describe self-reported physical activity levels in adult Fontan patients and examine associations between physical activity, perceived health status and QOL. The sample consisted of 177 Fontan patients (M<sub>age</sub> = 27.5 ± 7.6 years, 52% male) who reported their physical activity, perceived health status, and QOL as part of the cross-sectional Assessment of Patterns of Patient-Reported Outcomes in Adults with Congenital Heart disease - International Study. Descriptive statistics and univariate analyses of variance with planned contrasts were computed to describe physical activity characteristics. Mediation analyses tested whether perceived health status variables mediated the association between physical activity and QOL. Forty-six percent of patients were sedentary while only 40% met international physical activity guidelines. Higher physical activity was associated with younger age, lower NYHA class, higher perceived general health, and greater QOL. Patients who commuted by walking and engaged in sports reported better perceived health and QOL. Mediation analyses revealed that perceived general health but not NYHA functional class mediated the association between physical activity and QOL (αβ = 0.22, 95% confidence interval = 0.04 to 0.49). In conclusion, Fontan patients likely benefit from regular physical activity, having both higher perceived general health and functional capacity; greater perceived health status may contribute to enhanced QOL. In conclusion, these data support the pivotal role of regular physical activity for Fontan patients.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">31030969</PMID><DateCompleted><Year>2020</Year><Month>01</Month><Day>31</Day></DateCompleted><DateRevised><Year>2020</Year><Month>01</Month><Day>31</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1879-1913</ISSN><JournalIssue CitedMedium="Internet"><Volume>124</Volume><Issue>1</Issue><PubDate><Year>2019</Year><Month>07</Month><Day>01</Day></PubDate></JournalIssue><Title>The American journal of cardiology</Title><ISOAbbreviation>Am J Cardiol</ISOAbbreviation></Journal><ArticleTitle>Perceived Health Mediates Effects of Physical Activity on Quality of Life in Patients With a Fontan Circulation.</ArticleTitle><Pagination><MedlinePgn>144-150</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0002-9149(19)30398-4</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.amjcard.2019.03.039</ELocationID><Abstract><AbstractText>Patients with a Fontan circulation are at risk of a sedentary lifestyle. Given the direct relationship between physical activity and health, promotion of physical activity has the potential to improve outcomes, including quality of life (QOL). This study aimed to describe self-reported physical activity levels in adult Fontan patients and examine associations between physical activity, perceived health status and QOL. The sample consisted of 177 Fontan patients (M<sub>age</sub> = 27.5 ± 7.6 years, 52% male) who reported their physical activity, perceived health status, and QOL as part of the cross-sectional Assessment of Patterns of Patient-Reported Outcomes in Adults with Congenital Heart disease - International Study. Descriptive statistics and univariate analyses of variance with planned contrasts were computed to describe physical activity characteristics. Mediation analyses tested whether perceived health status variables mediated the association between physical activity and QOL. Forty-six percent of patients were sedentary while only 40% met international physical activity guidelines. Higher physical activity was associated with younger age, lower NYHA class, higher perceived general health, and greater QOL. Patients who commuted by walking and engaged in sports reported better perceived health and QOL. Mediation analyses revealed that perceived general health but not NYHA functional class mediated the association between physical activity and QOL (αβ = 0.22, 95% confidence interval = 0.04 to 0.49). In conclusion, Fontan patients likely benefit from regular physical activity, having both higher perceived general health and functional capacity; greater perceived health status may contribute to enhanced QOL. In conclusion, these data support the pivotal role of regular physical activity for Fontan patients.</AbstractText><CopyrightInformation>Copyright © 2019 Elsevier Inc. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Holbein</LastName><ForeName>Christina E</ForeName><Initials>CE</Initials><AffiliationInfo><Affiliation>Department of Child and Adolescent Psychiatry and Behavioral Sciences, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Veldtman</LastName><ForeName>Gruschen R</ForeName><Initials>GR</Initials><AffiliationInfo><Affiliation>King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Moons</LastName><ForeName>Philip</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>KU Leuven Department of Public Health and Primary Care, KU Leuven - University of Leuven, Leuven, Belgium; Institute of Health and Care Sciences, University of Gothenburg, Gothenburg, Sweden; Department of Paediatrics and Child Health, University of Cape Town, Cape Town, South Africa.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kovacs</LastName><ForeName>Adrienne H</ForeName><Initials>AH</Initials><AffiliationInfo><Affiliation>Peter Munk Cardiac Centre, University Health Network, University of Toronto, Toronto, Canada; Knight Cardiovascular Institute, Oregon Health & Science University, Portland, Oregon.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Luyckx</LastName><ForeName>Koen</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>School Psychology and Development in Context, KU Leuven - University of Leuven, Leuven, Belgium; UNIBS, University of the Free State Bloemfontein, Bloemfontein, South Africa.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Apers</LastName><ForeName>Silke</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>KU Leuven Department of Public Health and Primary Care, KU Leuven - University of Leuven, Leuven, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chidambarathanu</LastName><ForeName>Shanti</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Pediatric Cardiology, Frontier Lifeline Hospital (Dr. K. M. Cherian Heart Foundation), Chennai, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Soufi</LastName><ForeName>Alexandra</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Congenital Heart Disease, Louis Pradel Hospital, Hospices civils de Lyon, Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eriksen</LastName><ForeName>Katrine</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Adult Congenital Heart Disease Center, Oslo University Hospital - Rikshospitalet, Oslo, Norway.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jackson</LastName><ForeName>Jamie L</ForeName><Initials>JL</Initials><AffiliationInfo><Affiliation>Center for Biobehavioral Health, Nationwide Children's Hospital, Columbus, Ohio.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Enomoto</LastName><ForeName>Junko</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Adult Congenital Heart Disease, Chiba Cardiovascular Center, Chiba, Japan.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fernandes</LastName><ForeName>Susan M</ForeName><Initials>SM</Initials><AffiliationInfo><Affiliation>Stanford University School of Medicine, Department of Pediatrics and Medicine, Division of Pediatric Cardiology and Cardiovascular Medicine, Palo Alto, California.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Johansson</LastName><ForeName>Bengt</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Alday</LastName><ForeName>Luis</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Division of Cardiology, Hospital de Niños, Córdoba, Argentina.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dellborg</LastName><ForeName>Mikael</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Adult Congenital Heart Unit, Sahlgrenska University Hospital/Östra, Gothenburg, Sweden; Institute of Medicine, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Berghammer</LastName><ForeName>Malin</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Institute of Health and Care Sciences, University of Gothenburg, Gothenburg, Sweden; Department of Health Sciences, University West, Trollhättan, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Menahem</LastName><ForeName>Samuel</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Monash Heart, Monash Medical Centre, Monash University, Melbourne, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Caruana</LastName><ForeName>Maryanne</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Cardiology, Mater Dei Hospital, Birkirkara, Malta.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kutty</LastName><ForeName>Shelby</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Adult Congenital Heart Disease Center, University of Nebraska Medical Center/ Children's Hospital and Medical Center, Omaha, Nebraska.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mackie</LastName><ForeName>Andrew S</ForeName><Initials>AS</Initials><AffiliationInfo><Affiliation>Division of Cardiology, Stollery Children's Hospital, University of Alberta, Edmonton, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Thomet</LastName><ForeName>Corina</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Center for Congenital Heart Disease, Department of Cardiology, Inselspital - Bern University Hospital, University of Bern, Bern, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Budts</LastName><ForeName>Werner</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Division of Congenital and Structural Cardiology, University Hospitals Leuven, Leuven, Belgium; KU Leuven Department of Cardiovascular Sciences, KU Leuven - University of Leuven, Leuven, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>White</LastName><ForeName>Kamila</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Adult Congenital Heart Disease Center, Washington University and Barnes Jewish Heart & Vascular Center, University of Missouri, Saint Louis, Missouri.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sluman</LastName><ForeName>Maayke A</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Department of Cardiology, Academic Medical Center, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Callus</LastName><ForeName>Edward</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Clinical Psychology Service, IRCCS Policlinico San Donato, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cook</LastName><ForeName>Stephen C</ForeName><Initials>SC</Initials><AffiliationInfo><Affiliation>Adult Congenital Heart Disease Center, Helen DeVos Children's Hospital, Grand Rapids, Michigan.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Khairy</LastName><ForeName>Paul</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Adult Congenital Heart Center, Montreal Heart Institute, Université de Montréal, Montreal, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cedars</LastName><ForeName>Ari</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>The University of Texas Southwestern Medical Center, Dallas, Texas. Electronic address: ari.cedars@utsouthwestern.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>APPROACH-IS consortium and the International Society for Adult Congenital Heart Disease (ISACHD)</CollectiveName></Author></AuthorList><Language>eng</Language><DataBankList CompleteYN="Y"><DataBank><DataBankName>ClinicalTrials.gov</DataBankName><AccessionNumberList><AccessionNumber>NCT02150603</AccessionNumber></AccessionNumberList></DataBank></DataBankList><GrantList CompleteYN="Y"><Grant><GrantID>T32 HD068223</GrantID><Acronym>HD</Acronym><Agency>NICHD NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D052061">Research Support, N.I.H., Extramural</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2019</Year><Month>04</Month><Day>10</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Am J Cardiol</MedlineTA><NlmUniqueID>0207277</NlmUniqueID><ISSNLinking>0002-9149</ISSNLinking></MedlineJournalInfo><CitationSubset>AIM</CitationSubset><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003430" MajorTopicYN="N">Cross-Sectional Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015444" MajorTopicYN="Y">Exercise</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018729" MajorTopicYN="Y">Fontan Procedure</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006304" MajorTopicYN="Y">Health Status</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006330" MajorTopicYN="N">Heart Defects, Congenital</DescriptorName><QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName><QualifierName UI="Q000523" MajorTopicYN="Y">psychology</QualifierName><QualifierName UI="Q000601" MajorTopicYN="N">surgery</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011788" MajorTopicYN="Y">Quality of Life</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D057185" MajorTopicYN="N">Sedentary Behavior</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012649" MajorTopicYN="Y">Self Concept</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D057566" MajorTopicYN="N">Self Report</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2019</Year><Month>01</Month><Day>12</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2019</Year><Month>03</Month><Day>13</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2019</Year><Month>03</Month><Day>15</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2019</Year><Month>4</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>2</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2019</Year><Month>4</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">31030969</ArticleId><ArticleId IdType="pii">S0002-9149(19)30398-4</ArticleId><ArticleId IdType="doi">10.1016/j.amjcard.2019.03.039</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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