View source for Clin. Microbiol. Infect. (2009) Gautret

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;Authors:[[Has first author::P. Gautret]]{{Link to affiliation|l1=1}}, [[Has author::W. Yong]], [[Has author::G. Soula]], [[Has author::J. Gaudart]], [[Has author::J. Delmont]], [[Has author::A. Dia]], [[Has author::P. Parola]], [[Has author::P. Brouqui]]
;Affiliations:
* {{Affiliation anchor|l=1}} Service des Maladies Infectieuses et Tropicales, Hôpital Nord, AP-HM, Marseille, France.
;In:[[Is in journal::Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases (journal)|Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases]], ([[Publishing date::2009]])
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==Abstract==
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A prospective epidemiological study was conducted to evaluate the incidence of febrile cough episodes among adult Muslims travelling from Marseille to Saudi Arabia during the Hajj pilgrimage and to assess if use of statin had an influence on this incidence. In total, 580 individuals were presented with a questionnaire. A significant proportion of individuals had chronic medical disorders, e.g. diabetes mellitus (132, 22.8%) and hypertension (147, 25.3%). Pilgrims had a low level of education and a low employment rate. Sixty (10.3%) were treated with statins for hypercholesterolemia. Four hundred and fourty-seven pilgrims were presented a questionnaire on returning home. A total of 74 travellers (16.6%) experienced fever during their stay in Saudi Arabia (67 attended a doctor) and 271 (60.6%) had cough (259 attended a doctor); 70 travellers with cough were febrile (25.9%). Seventy per cent of the travellers who suffered cough episodes developed their first symptoms within 3 days, suggesting a human to human transmission of the responsible pathogen, with short incubation time as evidenced by a bimodal distribution of cough in two peaks at a 24 h interval. None of demographical and socioeconomic characteristics, underlying diseases or vaccination against influenza significantly affected the occurrence of cough. Diabetes correlated with an increased risk of febrile cough (OR = 2.02 (1.05-3.89)) as well as unemployment (OR = 2.22 (0.91-5.53)). Use of statins had no significant influence on the occurrence of cough and/or fever during the pilgrimage. This result suggests that while treatment with a statin has been demonstrated to reduce the mortality from severe sepsis associated with respiratory tract infections, it probably does not play a role in the outcome of regular febrile cough episodes as observed in the cohort studied here.
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==See also==
;External links:
* [https://pubmed.ncbi.nlm.nih.gov/19416305/ Link toward PubMed]
[[Category:Adult (MeSH)]]
[[Category:Aged (MeSH)]]
[[Category:Anticholesteremic Agents (therapeutic use)]]
[[Category:Cohort Studies (MeSH)]]
[[Category:Female (MeSH)]]
[[Category:France (epidemiology)]]
[[Category:Humans (MeSH)]]
[[Category:Incidence (MeSH)]]
[[Category:Male (MeSH)]]
[[Category:Middle Aged (MeSH)]]
[[Category:Prospective Studies (MeSH)]]
[[Category:Respiratory Tract Infections (drug therapy)]]
[[Category:Respiratory Tract Infections (epidemiology)]]
[[Category:Risk Factors (MeSH)]]
[[Category:Saudi Arabia (epidemiology)]]
[[Category:Socioeconomic Factors (MeSH)]]
[[Category:Surveys and Questionnaires (MeSH)]]
[[Category:Travel (MeSH)]]
[[Category:Treatment Outcome (MeSH)]]
[[Category:Young Adult (MeSH)]]
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[[fr:Clin. Microbiol. Infect. (2009) Gautret]]