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WSFEPP: neuropsychological function and diagnosis in early psychosis

Identifieur interne : 000216 ( Istex/Corpus ); précédent : 000215; suivant : 000217

WSFEPP: neuropsychological function and diagnosis in early psychosis

Auteurs : D. Fitzgerald ; S. Lucas ; M. A. Redoblado ; J. Brennan ; J. Anderson ; M. Sanbrook ; A. Taylor ; A. Harris

Source :

RBID : ISTEX:3471F34C68EEF0CEC939079B45952EC4D14F808C

Abstract

Objective  This study aimed to examine whether neuropsychological profiles of young first‐episode psychosis (FEP) patients varied according to diagnosis.

Url:
DOI: 10.1034/j.1600-0447.106.s413.1_137.x

Links to Exploration step

ISTEX:3471F34C68EEF0CEC939079B45952EC4D14F808C

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<p>Method  A sample of 94 FEP patients aged 13–25 were recruited as part of The Western Sydney First Episode Psychosis Project. Subjects completed a comprehensive battery of tests, grouped into 10 cognitive domains. Differences in cognitive profiles were examined in three diagnostic groups (schizophrenia, mood disorders, mixed psychosis) and compared to healthy controls. Correlations between neuropsychological deficits and clinical characteristics were explored.</p>
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<p>Results  Patterns of deficit were similar across diagnostic categories, but areas of selective deficit differentiated psychotic mood disorders from schizophrenia and other psychosis. Results indicated greater deficits in verbal learning and memory for schizophrenia than psychotic mood disorders. The Mood disorders group demonstrated selective deficits only on speeded processing tasks. Negative symptoms were associated with poorer neuropsychological functioning.</p>
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<b>Objective </b>
This study aimed to examine whether neuropsychological profiles of young first‐episode psychosis (FEP) patients varied according to diagnosis.</p>
<p>
<b>Method </b>
A sample of 94 FEP patients aged 13–25 were recruited as part of The Western Sydney First Episode Psychosis Project. Subjects completed a comprehensive battery of tests, grouped into 10 cognitive domains. Differences in cognitive profiles were examined in three diagnostic groups (schizophrenia, mood disorders, mixed psychosis) and compared to healthy controls. Correlations between neuropsychological deficits and clinical characteristics were explored.</p>
<p>
<b>Results </b>
Patterns of deficit were similar across diagnostic categories, but areas of selective deficit differentiated psychotic mood disorders from schizophrenia and other psychosis. Results indicated greater deficits in verbal learning and memory for schizophrenia than psychotic mood disorders. The Mood disorders group demonstrated selective deficits only on speeded processing tasks. Negative symptoms were associated with poorer neuropsychological functioning.</p>
<p>
<b>Conclusions </b>
Results confirm that significant cognitive deficits are evident in early psychosis and are present regardless of traditional diagnostic categorizations. However, results indicate that schizophrenia and mood disorders can be distinguished on the basis of areas of selective deficit.</p>
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<title>WSFEPP: neuropsychological function and diagnosis in early psychosis</title>
</titleInfo>
<titleInfo type="abbreviated" lang="en">
<title>3rd International Conference on Early Psychosis</title>
</titleInfo>
<titleInfo type="alternative" contentType="CDATA" lang="en">
<title>WSFEPP: neuropsychological function and diagnosis in early psychosis</title>
</titleInfo>
<name type="personal">
<namePart type="given">D.</namePart>
<namePart type="family">Fitzgerald</namePart>
<affiliation>Coral Tree Family Service, North Ryde, Australia,</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">S.</namePart>
<namePart type="family">Lucas</namePart>
<affiliation>Department of Psychology, Westmead Hospital, Australia,</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">M. A.</namePart>
<namePart type="family">Redoblado</namePart>
<affiliation>Department of Child & Adolescent Psychiatry, Westmead Hospital, Australia,</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">J.</namePart>
<namePart type="family">Brennan</namePart>
<affiliation>Department of Child & Adolescent Psychiatry, Westmead Hospital, Australia,</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">J.</namePart>
<namePart type="family">Anderson</namePart>
<affiliation>Department of Child & Adolescent Psychiatry, Westmead Hospital, Australia,</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">M.</namePart>
<namePart type="family">Sanbrook</namePart>
<affiliation>Department of Psychiatry, Nepean Hospital, Australia,</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">A.</namePart>
<namePart type="family">Taylor</namePart>
<affiliation>Department of Psychiatry, Nepean Hospital, Australia,</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">A.</namePart>
<namePart type="family">Harris</namePart>
<affiliation>Department of Psychological Medicine, University of Sydney, Australia</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<typeOfResource>text</typeOfResource>
<genre type="abstract" displayLabel="abstract"></genre>
<originInfo>
<publisher>Blackwell publishers</publisher>
<place>
<placeTerm type="text">Oxford, UK</placeTerm>
</place>
<dateIssued encoding="w3cdtf">2002-09</dateIssued>
<copyrightDate encoding="w3cdtf">2002</copyrightDate>
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<languageTerm type="code" authority="rfc3066">en</languageTerm>
<languageTerm type="code" authority="iso639-2b">eng</languageTerm>
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<abstract>Objective  This study aimed to examine whether neuropsychological profiles of young first‐episode psychosis (FEP) patients varied according to diagnosis.</abstract>
<abstract>Method  A sample of 94 FEP patients aged 13–25 were recruited as part of The Western Sydney First Episode Psychosis Project. Subjects completed a comprehensive battery of tests, grouped into 10 cognitive domains. Differences in cognitive profiles were examined in three diagnostic groups (schizophrenia, mood disorders, mixed psychosis) and compared to healthy controls. Correlations between neuropsychological deficits and clinical characteristics were explored.</abstract>
<abstract>Results  Patterns of deficit were similar across diagnostic categories, but areas of selective deficit differentiated psychotic mood disorders from schizophrenia and other psychosis. Results indicated greater deficits in verbal learning and memory for schizophrenia than psychotic mood disorders. The Mood disorders group demonstrated selective deficits only on speeded processing tasks. Negative symptoms were associated with poorer neuropsychological functioning.</abstract>
<abstract>Conclusions  Results confirm that significant cognitive deficits are evident in early psychosis and are present regardless of traditional diagnostic categorizations. However, results indicate that schizophrenia and mood disorders can be distinguished on the basis of areas of selective deficit.</abstract>
<relatedItem type="host">
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<title>Acta Psychiatrica Scandinavica</title>
</titleInfo>
<genre type="journal">journal</genre>
<identifier type="ISSN">0001-690X</identifier>
<identifier type="eISSN">1600-0447</identifier>
<identifier type="DOI">10.1111/(ISSN)1600-0447</identifier>
<identifier type="PublisherID">ACPS</identifier>
<part>
<date>2002</date>
<detail type="volume">
<caption>vol.</caption>
<number>106</number>
</detail>
<detail type="supplement">
<caption>Suppl. no.</caption>
<number>s413</number>
</detail>
<extent unit="pages">
<start>69</start>
<end>106</end>
</extent>
</part>
</relatedItem>
<identifier type="istex">3471F34C68EEF0CEC939079B45952EC4D14F808C</identifier>
<identifier type="DOI">10.1034/j.1600-0447.106.s413.1_137.x</identifier>
<identifier type="ArticleID">ACPSPO119_137</identifier>
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<recordContentSource>WILEY</recordContentSource>
<recordOrigin>Blackwell publishers</recordOrigin>
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