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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Social Capital and Sleep Quality in Individuals Who Self-Isolated for 14 Days During the Coronavirus Disease 2019 (COVID-19) Outbreak in January 2020 in China</title>
<author><name sortKey="Xiao, Han" sort="Xiao, Han" uniqKey="Xiao H" first="Han" last="Xiao">Han Xiao</name>
<affiliation><nlm:aff id="af1-medscimonit-26-e923921">Department of Respiration, Xuanwu Hospital, Capital Medical University, Beijing, P.R. China</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Zhang, Yan" sort="Zhang, Yan" uniqKey="Zhang Y" first="Yan" last="Zhang">Yan Zhang</name>
<affiliation><nlm:aff id="af2-medscimonit-26-e923921">College of Humanities and Social Sciences, Harbin Engineering University, Harbin, Heilongjiang, P.R. China</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kong, Desheng" sort="Kong, Desheng" uniqKey="Kong D" first="Desheng" last="Kong">Desheng Kong</name>
<affiliation><nlm:aff id="af2-medscimonit-26-e923921">College of Humanities and Social Sciences, Harbin Engineering University, Harbin, Heilongjiang, P.R. China</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Li, Shiyue" sort="Li, Shiyue" uniqKey="Li S" first="Shiyue" last="Li">Shiyue Li</name>
<affiliation><nlm:aff id="af3-medscimonit-26-e923921">School of Health Sciences, Wuhan University, Wuhan, Hubei, P.R. China</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Yang, Ningxi" sort="Yang, Ningxi" uniqKey="Yang N" first="Ningxi" last="Yang">Ningxi Yang</name>
<affiliation><nlm:aff id="af2-medscimonit-26-e923921">College of Humanities and Social Sciences, Harbin Engineering University, Harbin, Heilongjiang, P.R. China</nlm:aff>
</affiliation>
</author>
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<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">32194290</idno>
<idno type="pmc">7111105</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111105</idno>
<idno type="RBID">PMC:7111105</idno>
<idno type="doi">10.12659/MSM.923921</idno>
<date when="2020">2020</date>
<idno type="wicri:Area/Pmc/Corpus">000775</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Social Capital and Sleep Quality in Individuals Who Self-Isolated for 14 Days During the Coronavirus Disease 2019 (COVID-19) Outbreak in January 2020 in China</title>
<author><name sortKey="Xiao, Han" sort="Xiao, Han" uniqKey="Xiao H" first="Han" last="Xiao">Han Xiao</name>
<affiliation><nlm:aff id="af1-medscimonit-26-e923921">Department of Respiration, Xuanwu Hospital, Capital Medical University, Beijing, P.R. China</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Zhang, Yan" sort="Zhang, Yan" uniqKey="Zhang Y" first="Yan" last="Zhang">Yan Zhang</name>
<affiliation><nlm:aff id="af2-medscimonit-26-e923921">College of Humanities and Social Sciences, Harbin Engineering University, Harbin, Heilongjiang, P.R. China</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kong, Desheng" sort="Kong, Desheng" uniqKey="Kong D" first="Desheng" last="Kong">Desheng Kong</name>
<affiliation><nlm:aff id="af2-medscimonit-26-e923921">College of Humanities and Social Sciences, Harbin Engineering University, Harbin, Heilongjiang, P.R. China</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Li, Shiyue" sort="Li, Shiyue" uniqKey="Li S" first="Shiyue" last="Li">Shiyue Li</name>
<affiliation><nlm:aff id="af3-medscimonit-26-e923921">School of Health Sciences, Wuhan University, Wuhan, Hubei, P.R. China</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Yang, Ningxi" sort="Yang, Ningxi" uniqKey="Yang N" first="Ningxi" last="Yang">Ningxi Yang</name>
<affiliation><nlm:aff id="af2-medscimonit-26-e923921">College of Humanities and Social Sciences, Harbin Engineering University, Harbin, Heilongjiang, P.R. China</nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Medical Science Monitor : International Medical Journal of Experimental and Clinical Research</title>
<idno type="ISSN">1234-1010</idno>
<idno type="eISSN">1643-3750</idno>
<imprint><date when="2020">2020</date>
</imprint>
</series>
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<front><div type="abstract" xml:lang="en"><sec><title>Background</title>
<p>From the end of December 2019, coronavirus disease 2019 (COVID-19) began to spread in central China. Social capital is a measure of social trust, belonging, and participation. This study aimed to investigate the effects of social capital on sleep quality and the mechanisms involved in people who self-isolated at home for 14 days in January 2020 during the COVID-19 epidemic in central China.</p>
</sec>
<sec><title>Methods</title>
<p>Individuals (n=170) who self-isolated at home for 14 days in central China, completed self-reported questionnaires on the third day of isolation. Individual social capital was assessed using the Personal Social Capital Scale 16 (PSCI-16) questionnaire. Anxiety was assessed using the Self-Rating Anxiety Scale (SAS) questionnaire, stress was assessed using the Stanford Acute Stress Reaction (SASR) questionnaire, and sleep was assessed using the Pittsburgh Sleep Quality Index (PSQI) questionnaire. Path analysis was performed to evaluate the relationships between a dependent variable (social capital) and two or more independent variables, using Pearson’s correlation analysis and structural equation modeling (SEM).</p>
</sec>
<sec><title>Results</title>
<p>Low levels of social capital were associated with increased levels of anxiety and stress, but increased levels of social capital were positively associated with increased quality of sleep. Anxiety was associated with stress and reduced sleep quality, and the combination of anxiety and stress reduced the positive effects of social capital on sleep quality.</p>
</sec>
<sec><title>Conclusion</title>
<p>During a period of individual self-isolation during the COVID-19 virus epidemic in central China, increased social capital improved sleep quality by reducing anxiety and stress.</p>
</sec>
</div>
</front>
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<pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Med Sci Monit</journal-id>
<journal-id journal-id-type="iso-abbrev">Med. Sci. Monit</journal-id>
<journal-id journal-id-type="publisher-id">Medical Science Monitor</journal-id>
<journal-title-group><journal-title>Medical Science Monitor : International Medical Journal of Experimental and Clinical Research</journal-title>
</journal-title-group>
<issn pub-type="ppub">1234-1010</issn>
<issn pub-type="epub">1643-3750</issn>
<publisher><publisher-name>International Scientific Literature, Inc.</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">32194290</article-id>
<article-id pub-id-type="pmc">7111105</article-id>
<article-id pub-id-type="doi">10.12659/MSM.923921</article-id>
<article-id pub-id-type="publisher-id">923921</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Clinical Research</subject>
</subj-group>
</article-categories>
<title-group><article-title>Social Capital and Sleep Quality in Individuals Who Self-Isolated for 14 Days During the Coronavirus Disease 2019 (COVID-19) Outbreak in January 2020 in China</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Xiao</surname>
<given-names>Han</given-names>
</name>
<xref ref-type="aff" rid="af1-medscimonit-26-e923921">1</xref>
<xref ref-type="author-notes" rid="fn5-medscimonit-26-e923921">E</xref>
<xref ref-type="author-notes" rid="fn6-medscimonit-26-e923921">F</xref>
<xref ref-type="author-notes" rid="fn8-medscimonit-26-e923921">*</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Zhang</surname>
<given-names>Yan</given-names>
</name>
<xref ref-type="aff" rid="af2-medscimonit-26-e923921">2</xref>
<xref ref-type="author-notes" rid="fn1-medscimonit-26-e923921">A</xref>
<xref ref-type="author-notes" rid="fn3-medscimonit-26-e923921">C</xref>
<xref ref-type="author-notes" rid="fn6-medscimonit-26-e923921">F</xref>
<xref ref-type="author-notes" rid="fn8-medscimonit-26-e923921">*</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kong</surname>
<given-names>Desheng</given-names>
</name>
<xref ref-type="aff" rid="af2-medscimonit-26-e923921">2</xref>
<xref ref-type="author-notes" rid="fn3-medscimonit-26-e923921">C</xref>
<xref ref-type="author-notes" rid="fn4-medscimonit-26-e923921">D</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Li</surname>
<given-names>Shiyue</given-names>
</name>
<xref ref-type="aff" rid="af3-medscimonit-26-e923921">3</xref>
<xref ref-type="author-notes" rid="fn1-medscimonit-26-e923921">A</xref>
<xref ref-type="author-notes" rid="fn2-medscimonit-26-e923921">B</xref>
<xref ref-type="author-notes" rid="fn7-medscimonit-26-e923921">G</xref>
</contrib>
<contrib contrib-type="author" corresp="yes"><name><surname>Yang</surname>
<given-names>Ningxi</given-names>
</name>
<xref ref-type="aff" rid="af2-medscimonit-26-e923921">2</xref>
<xref ref-type="author-notes" rid="fn1-medscimonit-26-e923921">A</xref>
<xref ref-type="author-notes" rid="fn5-medscimonit-26-e923921">E</xref>
<xref ref-type="author-notes" rid="fn6-medscimonit-26-e923921">F</xref>
<xref ref-type="author-notes" rid="fn7-medscimonit-26-e923921">G</xref>
</contrib>
</contrib-group>
<aff id="af1-medscimonit-26-e923921"><label>1</label>
Department of Respiration, Xuanwu Hospital, Capital Medical University, Beijing, P.R. China</aff>
<aff id="af2-medscimonit-26-e923921"><label>2</label>
College of Humanities and Social Sciences, Harbin Engineering University, Harbin, Heilongjiang, P.R. China</aff>
<aff id="af3-medscimonit-26-e923921"><label>3</label>
School of Health Sciences, Wuhan University, Wuhan, Hubei, P.R. China</aff>
<author-notes><corresp id="c1-medscimonit-26-e923921">Corresponding Author: Ningxi Yang, e-mail: <email>yangningxi@bjmu.edu.cn</email>
</corresp>
<fn id="fn1-medscimonit-26-e923921"><label>A</label>
<p>Study Design</p>
</fn>
<fn id="fn2-medscimonit-26-e923921"><label>B</label>
<p>Data Collection</p>
</fn>
<fn id="fn3-medscimonit-26-e923921"><label>C</label>
<p>Statistical Analysis</p>
</fn>
<fn id="fn4-medscimonit-26-e923921"><label>D</label>
<p>Data Interpretation</p>
</fn>
<fn id="fn5-medscimonit-26-e923921"><label>E</label>
<p>Manuscript Preparation</p>
</fn>
<fn id="fn6-medscimonit-26-e923921"><label>F</label>
<p>Literature Search</p>
</fn>
<fn id="fn7-medscimonit-26-e923921"><label>G</label>
<p>Funds Collection</p>
</fn>
<fn id="fn8-medscimonit-26-e923921"><label>*</label>
<p>Han Xiao and Yan Zhang are both first authors and contributed equally to this study</p>
</fn>
</author-notes>
<pub-date pub-type="collection"><year>2020</year>
</pub-date>
<pub-date pub-type="epub"><day>20</day>
<month>3</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epreprint"><day>12</day>
<month>3</month>
<year>2020</year>
</pub-date>
<volume>26</volume>
<fpage>e923921-1</fpage>
<lpage>e923921-8</lpage>
<history><date date-type="received"><day>01</day>
<month>3</month>
<year>2020</year>
</date>
<date date-type="accepted"><day>07</day>
<month>3</month>
<year>2020</year>
</date>
</history>
<permissions><copyright-statement>© Med Sci Monit, 2020</copyright-statement>
<copyright-year>2020</copyright-year>
<license license-type="open-access"><license-p>This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (<ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by-nc-nd/4.0/">CC BY-NC-ND 4.0</ext-link>
)</license-p>
</license>
</permissions>
<abstract><sec><title>Background</title>
<p>From the end of December 2019, coronavirus disease 2019 (COVID-19) began to spread in central China. Social capital is a measure of social trust, belonging, and participation. This study aimed to investigate the effects of social capital on sleep quality and the mechanisms involved in people who self-isolated at home for 14 days in January 2020 during the COVID-19 epidemic in central China.</p>
</sec>
<sec><title>Methods</title>
<p>Individuals (n=170) who self-isolated at home for 14 days in central China, completed self-reported questionnaires on the third day of isolation. Individual social capital was assessed using the Personal Social Capital Scale 16 (PSCI-16) questionnaire. Anxiety was assessed using the Self-Rating Anxiety Scale (SAS) questionnaire, stress was assessed using the Stanford Acute Stress Reaction (SASR) questionnaire, and sleep was assessed using the Pittsburgh Sleep Quality Index (PSQI) questionnaire. Path analysis was performed to evaluate the relationships between a dependent variable (social capital) and two or more independent variables, using Pearson’s correlation analysis and structural equation modeling (SEM).</p>
</sec>
<sec><title>Results</title>
<p>Low levels of social capital were associated with increased levels of anxiety and stress, but increased levels of social capital were positively associated with increased quality of sleep. Anxiety was associated with stress and reduced sleep quality, and the combination of anxiety and stress reduced the positive effects of social capital on sleep quality.</p>
</sec>
<sec><title>Conclusion</title>
<p>During a period of individual self-isolation during the COVID-19 virus epidemic in central China, increased social capital improved sleep quality by reducing anxiety and stress.</p>
</sec>
</abstract>
<kwd-group><title>MeSH Keywords</title>
<kwd>Anxiety</kwd>
<kwd>Pneumonia</kwd>
<kwd>Sleep</kwd>
</kwd-group>
</article-meta>
</front>
<body><sec><title>Background</title>
<p>From the end of December 2019, coronavirus disease 2019 (COVID-19) began to spread in central China [<xref rid="b1-medscimonit-26-e923921" ref-type="bibr">1</xref>
,<xref rid="b2-medscimonit-26-e923921" ref-type="bibr">2</xref>
]. As of March 4<sup>th</sup>
2020, more than 80,560 people had been diagnosed with COVID-19, and 3010 patients had died from COVID-19 infection in China [<xref rid="b3-medscimonit-26-e923921" ref-type="bibr">3</xref>
]. Outside China, the disease spread worldwide, nearly 13,570 patients were diagnosed with COVID-19 infection, and 270 patients had died from infection by this novel virus [<xref rid="b3-medscimonit-26-e923921" ref-type="bibr">3</xref>
]. The outbreak of COVID-19 was recognized by the World Health Organisation (WHO) as a Public Health Emergency of International Concern (PHEIC) that endangers international public health [<xref rid="b4-medscimonit-26-e923921" ref-type="bibr">4</xref>
]. The WHO has defined a PHEIC as an infectious disease with international spread, or an unusual, serious, or unexpected public health event that exceeds local health resources, or that requires immediate international action [<xref rid="b4-medscimonit-26-e923921" ref-type="bibr">4</xref>
].</p>
<p>Infectious disease epidemics not only affect the physical health of patients but also affect the psychological health and wellbeing of the non-infected population. Previous studies have shown that the prevalence of novel infectious diseases, such as severe acute respiratory syndrome (SARS), can increase anxiety, depression, and stress levels in the general population [<xref rid="b5-medscimonit-26-e923921" ref-type="bibr">5</xref>
]. These negative emotions also affect sleep [<xref rid="b6-medscimonit-26-e923921" ref-type="bibr">6</xref>
]. At the time of the COVID-19 epidemic in central China, some individuals with mild illness, suspected cases of infection, and people who had been in close contact with patients or a potentially high-risk environment were isolated at home. Even if the self-isolated individuals do not develop an infection and remain physically well, they often suffer from negative psychological effects. Importantly, the effects of mental health and sleep on immunity have been shown by previous studies [<xref rid="b7-medscimonit-26-e923921" ref-type="bibr">7</xref>
]. Good quality sleep can help improve immunity to viral infection [<xref rid="b8-medscimonit-26-e923921" ref-type="bibr">8</xref>
]. Therefore, mental health and sleep quality are important considerations in the population of people who have self-isolated due to their increased risk of COVID-19 infection.</p>
<p>Psychological wellbeing and sleep are affected by several factors. Social factors, such as economic burden, family support, social support, and social capital, are also important factors [<xref rid="b9-medscimonit-26-e923921" ref-type="bibr">9</xref>
]. Recently, several studies have investigated the influence of social factors on mental health [<xref rid="b10-medscimonit-26-e923921" ref-type="bibr">10</xref>
]. Social support is a common variable, but there has been little research on the relationship between social capital and health [<xref rid="b11-medscimonit-26-e923921" ref-type="bibr">11</xref>
,<xref rid="b12-medscimonit-26-e923921" ref-type="bibr">12</xref>
].</p>
<p>The concept of social capital was first proposed by the French sociologist, Portes, in 1980 [<xref rid="b13-medscimonit-26-e923921" ref-type="bibr">13</xref>
]. Portes defined social capital as a collection of actual or potential resources that include social trust, belonging, and participation, and believed that these resources were associated with a lasting network of mutual recognition [<xref rid="b13-medscimonit-26-e923921" ref-type="bibr">13</xref>
]. In 1997, Lynch developed the concept of social capital as the will to generate social cohesion, trust, and participation in community activities [<xref rid="b14-medscimonit-26-e923921" ref-type="bibr">14</xref>
]. There are differences between social support and social capital. Social support represents the size and source of social networks of people helping others, as well as emotional, material, and informative supportive functions [<xref rid="b15-medscimonit-26-e923921" ref-type="bibr">15</xref>
]. Social capital includes social trust, belonging, and social participation. The effect of social capital on psychological wellbeing has been shown by previous studies [<xref rid="b16-medscimonit-26-e923921" ref-type="bibr">16</xref>
].</p>
<p>However, in China, studies on the role of social capital on wellbeing are limited, particularly in the context of acute infectious disease. Therefore, this study aimed to investigate the effects of social capital on sleep quality and the mechanisms involved in people who self-isolated at home for 14 days in January 2020, during the COVID-19 epidemic in central China. In this study, path analysis was performed to evaluate the relationships between a dependent variable (social capital) and two or more independent variables (anxiety, stress, and sleep), using Pearson’s correlation analysis and structural equation modeling (SEM).</p>
</sec>
<sec sec-type="materials|methods"><title>Material and Methods</title>
<sec><title>Ethical approval</title>
<p>This study was conducted in accordance with the Declaration of Helsinki. All participants provided signed informed consent to participate in the study. The Wuhan University School of Medicine Ethics Committee approved the study procedures (Approval number: 20190320).</p>
</sec>
<sec sec-type="methods|subjects"><title>Study participants</title>
<p>A total of 170 people were identified who were isolated at home for 14 days in January 2020 in central China, during the epidemic of coronavirus disease 2019 (COVID-19). The study included adult individuals who had self-isolated following mild infection with COVID-19, suspected cases of COVID-19 infection, people in close contact with patients infected with COVID-19, and people who may have been exposed to the virus in the environment. All study participants were required to be able to provide informed consent to participate in the study. All responses to the study questionnaires were anonymized.</p>
</sec>
<sec sec-type="methods"><title>Study design</title>
<p>Cross-sectional study design was used that included the demographic and sociological data for each participant and disease-related information. On the third day of self-isolation, the participants completed self-reported questionnaires. Individual social capital was assessed using the Personal Social Capital Scale 16 (PSCI-16) questionnaire. Anxiety was assessed using the Self-Rating Anxiety Scale (SAS) questionnaire, stress was assessed using the Stanford Acute Stress Reaction (SASR) questionnaire, and sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI) questionnaire. The questionnaire responses were compared to determine the relationships between anxiety, stress, sleep, and social capital.</p>
</sec>
<sec><title>Measurement of social capital using the PSCI-16 questionnaire</title>
<p>The PSCI-16 questionnaire was used to assess social capital, using a 5-point Likert scale that contained 16 items. Each item scored from 1–5, and the total score ranged from 16–80. A higher score indicated lower social capital. The PSCI-16 questionnaire included the following 16 questions:</p>
<list list-type="order"><list-item><p>How many friends do you have?</p>
</list-item>
<list-item><p>How many relatives, neighbors, friends, co-workers, and classmates do you have?</p>
</list-item>
<list-item><p>Among your co-workers, how many do you trust?</p>
</list-item>
<list-item><p>Among your relatives, how many do you trust?</p>
</list-item>
<list-item><p>Among all your relatives, neighbors, friends, co-workers, and classmates, how many have connections with others?</p>
</list-item>
<list-item><p>Among all your relatives, neighbors, friends, co-workers, and classmates, how many have a professional job?</p>
</list-item>
<list-item><p>How many of your co-workers will help you when asked?</p>
</list-item>
<list-item><p>How many of your friends will help you when asked?</p>
</list-item>
<list-item><p>How do you rate the number of cultural, recreational, and leisure groups and organizations are in your community?</p>
</list-item>
<list-item><p>How do you rate the number of governmental, political, economic, and social groups and organizations in your community?</p>
</list-item>
<list-item><p>How many of these groups and organizations possess broad social connections?</p>
</list-item>
<list-item><p>How many of these groups and organizations have social influence?</p>
</list-item>
<list-item><p>How many of the cultural, recreational, and leisure groups and organizations represent your interests?</p>
</list-item>
<list-item><p>How many of the governmental, political, economic, and social groups and organizations represent your interests?</p>
</list-item>
<list-item><p>How many of the governmental, political, economic, and social groups and organizations will help you when asked?</p>
</list-item>
<list-item><p>How many of the cultural, recreational, and leisure groups and organizations will help you when asked? [<xref rid="b17-medscimonit-26-e923921" ref-type="bibr">17</xref>
].</p>
</list-item>
</list>
<p>The Cronbach’s alpha for internal consistency of this questionnaire was previously determined to be 0.812.</p>
</sec>
<sec><title>Measurement of anxiety using the SAS questionnaire</title>
<p>The SAS questionnaire was used to measure the levels of anxiety of the study participants. There were 20 items in the scale. Each item was divided into four grades according to the feelings of the respondents in the past week and the frequency of symptoms was mainly evaluated. The cumulative score of 20 items was the total SAS score. The standard total score was obtained by taking the total score ×1.25. The higher the score, the greater the degree of anxiety [<xref rid="b18-medscimonit-26-e923921" ref-type="bibr">18</xref>
]. The Cronbach’s alpha for internal consistency of this questionnaire was previously determined to be 0.867.</p>
</sec>
<sec><title>Measurement of stress using the SASR questionnaire</title>
<p>The SASR questionnaire using a six-point Likert scale, which contained 30 items, was used to measure stress. Each item scored from 0–5, with the total scores from 0–150. A higher score indicated higher stress levels [<xref rid="b19-medscimonit-26-e923921" ref-type="bibr">19</xref>
]. The Cronbach’s alpha for internal consistency of this questionnaire was previously determined to be 0.803.</p>
</sec>
<sec><title>Measurement of sleep quality using the PSQI questionnaire</title>
<p>The PSQI questionnaire was used to measure the sleep quality of the study participants. There were 18 items that consisted of seven dimensions, including sleep quality, sleep duration, sleep latency, habitual sleep efficiency, sleep disturbances, use of sleeping×medications, and daytime dysfunction. Each dimension was scored from 0–3, and the total score, which was the sum of the scores from each dimension, ranged from 0–20. A higher score indicated lower sleep quality [<xref rid="b20-medscimonit-26-e923921" ref-type="bibr">20</xref>
]. The Cronbach’s alpha for internal consistency of this questionnaire was previously determined to be 0.872.</p>
</sec>
<sec sec-type="methods"><title>Statistical analysis</title>
<p>Data were presented as the mean ± standard deviation (SD). Path analysis, or multiple regression analysis, was performed to evaluate the relationships between a dependent variable (social capital) and two or more independent variables, using Pearson correlation analysis (r) and structural equation modeling (SEM). The indices for the degree of fit of the SEM were calculated. SPSS Amos version 21.0 (IBM, Armonk, NY, USA) was used to measure the mediation effects of the study variables, with a bootstrap number set as 5000 to test the significance of specific mediation effects, followed by the nonparametric percentile bootstrap method with SD correction. EpiData Entry version 3.1 and SAS version 9.4 were used for data entry and analysis, respectively. A P-value <0.05 was considered to be statistically significant.</p>
</sec>
</sec>
<sec sec-type="results"><title>Results</title>
<sec sec-type="methods|subjects"><title>Study participants</title>
<p>There were 200 people who were initially invited to participate, of which 170 were included in the study, with a participation rate of 85%. The mean age of the study participants was 37.78±4.12 years. The demographic and disease-related data of the study participants are shown in <xref rid="t1-medscimonit-26-e923921" ref-type="table">Table 1</xref>
.</p>
</sec>
<sec><title>The association between social capital, stress, anxiety, and sleep quality</title>
<p>Individual social capital was assessed using the Personal Social Capital Scale 16 (PSCI-16) questionnaire; anxiety was assessed using the Self-Rating Anxiety Scale (SAS) questionnaire; stress was assessed using the Stanford Acute Stress Reaction (SASR) questionnaire; and sleep was assessed using the Pittsburgh Sleep Quality Index (PSQI) questionnaire. Pearson’s correlation analysis showed that the PSCI-16 score for social capital was positively associated with the SAS score for anxiety (r=0.619, P<0.01), the SASR score for stress (r=0.543, P<0.01), and the PSQI score for sleep quality (r=0.479, P<0.01).</p>
<p>The SAS score for anxiety for the study participants was positively associated with the SASR score for stress (r=0.553, P<0.01), and the PSQI score for sleep quality (r=0.523, P<0.01). The SASR score for stress was positively associated with the PSQI score for sleep quality (r=0.628, P<0.01). These findings showed that the social capital of the study participants who self-isolated during the COVID-19 epidemic improved sleep quality, which was reduced by anxiety and stress. Anxiety levels correlated with stress levels, which reduced sleep quality. The results are summarized in <xref rid="t2-medscimonit-26-e923921" ref-type="table">Table 2</xref>
.</p>
</sec>
<sec sec-type="methods"><title>Path analysis and mediation analysis using structural equation modeling (SEM) of social capital on stress, anxiety, and sleep quality</title>
<p>Path analysis and mediation analysis using structural equation modeling (SEM) were used to investigate the relationships between the four variables in this study. The effect of PSCI-16 score for social capital on the PSQI score for sleep quality did not reach statistical significance, and this path was deleted from the model, as shown in <xref ref-type="fig" rid="f1-medscimonit-26-e923921">Figure 1</xref>
. The indices for the degree of fit of the SEM were ideal, as shown by the goodness of fit index (GFI) of 0.995, the comparative fitness index (CFI) of 0.997, the Tucker Lewis index (TLI) of 0.981, the incremental fit index (IFI) of 0.997, the normed fit index (NFI) of 0.993, the adjusted goodness of fit index (AGFI) of 0.948, the root mean square error of approximation (RMSEA) of 0.068, and the chi-squared (χ<sup>2</sup>
) to degree of freedom (df) ratio (χ<sup>2</sup>
/df ) of 1.781.</p>
<p><xref rid="t3-medscimonit-26-e923921" ref-type="table">Table 3</xref>
shows the normalized path coefficient. The PSCI-16 score of the study participants was positively associated with the SAS score (β=0.619, P<0.001) and the SASR score (β=0.327, P<0.001). The SAS score of the study participants significantly affected the SASR score (β=0.351, P<0.001) and the PSQI score (β=0.253, P<0.001). The SASR score of the study participants was positively associated with the PSQI score (β=0.488, P<0.001). According to the scores from the PSCI-16, SAS, SASR, and PSQI questionnaires, social capital reduced anxiety and stress; increased anxiety levels reinforced stress levels, and reduced sleep quality.</p>
<p>The indices for the degree of fit of the SEM were calculated. SPSS Amos version 21.0 (IBM, Armonk, NY, USA) was used to measure the mediation effects of the study variables, with a bootstrap number set as 5000 to test the significance of specific mediation effects, followed by the nonparametric percentile bootstrap method with standard deviation (SD) correction. The following path was identified: PSCI-16 score for social capital → the SAS score for anxiety → the PSQI score for sleep quality. The SAS score for anxiety had a significant mediating effect between the PSCI-16 score for social capital and the PSQI score for sleep quality (β=0.157, P=0.002) when the confidence interval did not include 0. In the path of the PSCI-16 score for social capital → the SASR score for stress → the PSQI score for sleep quality, the SAS score for anxiety had a significant mediating effect between the PSCI-16 score for social capital and the PSQI score for sleep quality (β=0.159, P<0.0001), when 0 was not included in the confidence interval. The results are shown in <xref rid="t4-medscimonit-26-e923921" ref-type="table">Table 4</xref>
.</p>
</sec>
</sec>
<sec sec-type="discussion"><title>Discussion</title>
<p>The aim of this study was to investigate the effects of social capital on sleep quality and the mechanisms involved in people who self-isolated at home for 14 days in January 2020 during the coronavirus disease 2019 (COVID-19) epidemic in central China. Social capital was assessed using the Personal Social Capital Scale 16 (PSCI-16) questionnaire, which measured social trust, belonging, and participation. Anxiety was assessed using the Self-Rating Anxiety Scale (SAS) questionnaire, stress was assessed using the Stanford Acute Stress Reaction (SASR) questionnaire, and sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI) questionnaire. Path analysis was performed to evaluate the relationships between a dependent variable (social capital) and two or more independent variables, using Pearson’s correlation analysis and structural equation modeling (SEM).</p>
<p>The findings from this study showed that anxiety and stress of isolated individuals were at high levels, while the sleep quality was low, which indicates that psychological health should be considered for individuals who isolate during epidemics and that levels of social capital may affect mental health and sleep. These findings are supported by previous studies, including the findings reported in 2012 by Valencia-Garcia et al., which confirmed that increased social capital reduced the levels of depression and anxiety [<xref rid="b21-medscimonit-26-e923921" ref-type="bibr">21</xref>
]. Li et al. showed that for children living in poverty, more family members, peer support, and school friends in their social capital were associated with better mental health [<xref rid="b22-medscimonit-26-e923921" ref-type="bibr">22</xref>
]. Yamada et al. showed that social capital contributed to reducing distress and preventing complications in patients with diabetes [<xref rid="b23-medscimonit-26-e923921" ref-type="bibr">23</xref>
].</p>
<p>The findings from the present study, and the findings from previous studies, provide support for improving physical and mental health from the perspective of social capital and may be applied to individuals who self-isolate during epidemics, such as the recent COVID-19 epidemic in central China. Individuals who self-isolate at home will suffer from physical stress due to lack of space for physical activity, stress due to limited social interactions, and anxiety associated with fear of the consequences of infection. Most individuals who self-isolate live alone or live with their families and may be more likely to feel lonely. Also, because they are isolated at home rather than in the hospital, they may feel more insecure than the patients who have been hospitalized, with increased uncertainty about their own risk of developing severe disease, or of not being diagnosed or treated in time. Therefore, the mental health of these individuals requires more attention. Social capital may require attention to reduce negative emotions and to cope with the risks from an infection epidemic with a more positive attitude.</p>
<p>This study found that the influence of social capital on sleep was mediated by anxiety and stress. In the first path identified, social capital affected anxiety, and anxiety directly influenced sleep quality. Social capital affects anxiety because when an individual has a wide social network, they may be more likely to interact with other people [<xref rid="b24-medscimonit-26-e923921" ref-type="bibr">24</xref>
]. Social support and social resources reduce negative emotions, such as anxiety [<xref rid="b25-medscimonit-26-e923921" ref-type="bibr">25</xref>
]. Therefore, when individuals are isolated, including during epidemics, online social groups that expand social networks and provide mutual support may reduce the anxiety of isolation [<xref rid="b26-medscimonit-26-e923921" ref-type="bibr">26</xref>
]. The effects of anxiety on sleep have been previously identified [<xref rid="b27-medscimonit-26-e923921" ref-type="bibr">27</xref>
]. Subjectively, people with anxiety may find it difficult to fall asleep, or they may wake up easily [<xref rid="b28-medscimonit-26-e923921" ref-type="bibr">28</xref>
]. Anxiety may lead to increased cortisol levels, changes in cortisol secretion rhythms, and reduced melatonin synthesis, all of which reduces sleep quality [<xref rid="b29-medscimonit-26-e923921" ref-type="bibr">29</xref>
,<xref rid="b30-medscimonit-26-e923921" ref-type="bibr">30</xref>
].</p>
<p>In the second path identified in this study, social capital affected stress, and then stress affected sleep. The stress response refers to the individual nonspecific response caused by various stressors [<xref rid="b31-medscimonit-26-e923921" ref-type="bibr">31</xref>
]. Stress is closely associated with mood, behavior, a sense of wellbeing, and health [<xref rid="b32-medscimonit-26-e923921" ref-type="bibr">32</xref>
]. People who have more social capital usually have less stress because they have spiritual or material support from others. Social support helps to reduce the perception and evaluation of the threat of stress events, the physiological response and inappropriate behavior caused by stress, and the level of fear and anxiety induced by stress [<xref rid="b33-medscimonit-26-e923921" ref-type="bibr">33</xref>
,<xref rid="b34-medscimonit-26-e923921" ref-type="bibr">34</xref>
]. Stress is associated with sleep quality [<xref rid="b35-medscimonit-26-e923921" ref-type="bibr">35</xref>
]. When individuals experience stress, they often feel physical tension and mental pressure, they are more sensitive to the sleeping environment, or they focus on sleep too much, which will reduce their sleep quality [<xref rid="b36-medscimonit-26-e923921" ref-type="bibr">36</xref>
]. Also, some variables may interact with each other. For example, anxiety may increase stress, and stress may increase anxiety [<xref rid="b37-medscimonit-26-e923921" ref-type="bibr">37</xref>
]. Also, increased anxiety may lead to poor sleep, and poor sleep may increase anxiety [<xref rid="b38-medscimonit-26-e923921" ref-type="bibr">38</xref>
]. Therefore, all the variables included in the present study, social capital, stress, anxiety, and sleep require attention to prevent a negative cycle of psychological and physical harm.</p>
<p>Therefore, more measures are needed to improve the social capital and mental health status of isolated people during epidemics of infectious disease. For example, professional medical staff should provide online health education to reduce uncertainty and panic caused by a lack of knowledge of new infections and diseases. Social workers and psychotherapists may provide online help or support or support by phone to provide encouragement to communicate with relatives and friends using the internet or phone. These approaches to improving mental health and sleep may also improve immune function, which may improve the ability to resist infectious disease [<xref rid="b39-medscimonit-26-e923921" ref-type="bibr">39</xref>
,<xref rid="b40-medscimonit-26-e923921" ref-type="bibr">40</xref>
].</p>
<p>This study investigated social capital, anxiety, stress, and sleep quality in a population who self-isolated for 14 days during the COVID-19 outbreak in January 2020 and analyzed the relationships between the variables. Social capital affected sleep quality through the mediation effects on anxiety and stress, as people who had high levels of social capital had better sleep quality. However, this study had several limitations. The study sample size was small, and a cross-sectional study design was used, which may have prevented the identification of other associations between social capital and sleep. Also, social capital was measured using the PSCI-16 questionnaire, and the data relied on the ability of the individual to interpret the questions and provide accurate responses, but these responses were not verified objectively. Therefore, some causal relationships may have been missed. Further cohort studies with more samples should be performed, and non-subjective methods should be used. For example, sleep can be measured objectively by polysomnography, and stress levels can be detected using objective measurements of serum cortisol levels.</p>
</sec>
<sec sec-type="conclusions"><title>Conclusions</title>
<p>This study aimed to investigate the effects of social capital on sleep quality and the mechanisms involved in people who self-isolated at home for 14 days in January 2020, during the coronavirus disease 2019 (COVID-19) epidemic in central China. In this study, path analysis was performed to evaluate the relationships between a dependent variable (social capital) and two or more independent variables (anxiety, stress, and sleep), using Pearson’s correlation analysis and structural equation modeling (SEM). During a period of individual self-isolation during the COVID-19 virus epidemic, increased social capital improved sleep quality by reducing anxiety and stress. These findings may have implications for public health provision during epidemics of infectious disease, including improvements in social capital.</p>
</sec>
</body>
<back><ack><title>Acknowledgments</title>
<p>The authors thank all the participants who took part in the study. This study was funded by the Basic Research Project of Coronavirus Disease 2019 Epidemic of Fundamental Research Funds for the Central Universities, Harbin Engineering University.</p>
</ack>
<fn-group><fn id="fn9-medscimonit-26-e923921" fn-type="COI-statement"><p><bold>Conflict of interest</bold>
</p>
<p>None.</p>
</fn>
<fn id="fn10-medscimonit-26-e923921"><p><bold>Source of support:</bold>
This study was funded by the Basic Research Project of Coronavirus Disease 2019 Epidemic of Fundamental Research Funds for the Central Universities, Harbin Engineering University</p>
</fn>
</fn-group>
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<pub-id pub-id-type="pmid">25040302</pub-id>
</element-citation>
</ref>
<ref id="b37-medscimonit-26-e923921"><label>37</label>
<element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Thapar</surname>
<given-names>A</given-names>
</name>
<name><surname>Kerr</surname>
<given-names>M</given-names>
</name>
<name><surname>Harold</surname>
<given-names>G</given-names>
</name>
</person-group>
<article-title>Stress, anxiety, depression, and epilepsy: Investigating the relationship between psychological factors and seizures</article-title>
<source>Epilepsy Behav</source>
<year>2009</year>
<volume>14</volume>
<issue>1</issue>
<fpage>134</fpage>
<lpage>40</lpage>
<pub-id pub-id-type="pmid">18824131</pub-id>
</element-citation>
</ref>
<ref id="b38-medscimonit-26-e923921"><label>38</label>
<element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Babson</surname>
<given-names>KA</given-names>
</name>
<name><surname>Badour</surname>
<given-names>CL</given-names>
</name>
<name><surname>Feldner</surname>
<given-names>MT</given-names>
</name>
<etal></etal>
</person-group>
<article-title>The relationship of sleep quality and PTSD to anxious reactivity from idiographic traumatic event script-driven imagery</article-title>
<source>J Trauma Stress</source>
<year>2012</year>
<volume>25</volume>
<issue>5</issue>
<fpage>503</fpage>
<lpage>10</lpage>
<pub-id pub-id-type="pmid">23047429</pub-id>
</element-citation>
</ref>
<ref id="b39-medscimonit-26-e923921"><label>39</label>
<element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kurien</surname>
<given-names>PA</given-names>
</name>
<name><surname>Chong</surname>
<given-names>SY</given-names>
</name>
<name><surname>Ptáček</surname>
<given-names>LJ</given-names>
</name>
<etal></etal>
</person-group>
<article-title>Sick and tired: how molecular regulators of human sleep schedules and duration impact immune function</article-title>
<source>Curr Opin Neurobiol</source>
<year>2013</year>
<volume>23</volume>
<issue>5</issue>
<fpage>873</fpage>
<lpage>79</lpage>
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</element-citation>
</ref>
<ref id="b40-medscimonit-26-e923921"><label>40</label>
<element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Hulett</surname>
<given-names>JM</given-names>
</name>
<name><surname>Armer</surname>
<given-names>JM</given-names>
</name>
</person-group>
<article-title>A systematic review of spiritually based interventions and psychoneuroimmunological outcomes in breast cancer survivorship</article-title>
<source>Integr Cancer Ther</source>
<year>2016</year>
<volume>15</volume>
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<fpage>405</fpage>
<lpage>23</lpage>
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</back>
<floats-group><fig id="f1-medscimonit-26-e923921" position="float"><label>Figure 1</label>
<caption><p>Path analysis results from the Personal Social Capital Scale 16 (PSCI-16), the Self-Rating Anxiety Scale (SAS), the Stanford Acute Stress Reaction (SASR), and the Pittsburgh Sleep Quality Index (PSQI) of the study participants.</p>
</caption>
<graphic xlink:href="medscimonit-26-e923921-g001"></graphic>
</fig>
<table-wrap id="t1-medscimonit-26-e923921" position="float"><label>Table 1</label>
<caption><p>Participants’ demography and disease related information.</p>
</caption>
<table frame="hsides" rules="rows"><thead><tr><th valign="middle" align="center" rowspan="1" colspan="1">Variable</th>
<th valign="middle" align="center" rowspan="1" colspan="1">Number</th>
<th valign="middle" align="center" rowspan="1" colspan="1">%</th>
</tr>
</thead>
<tbody><tr><td colspan="3" valign="middle" align="left" rowspan="1">Gender</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1"> Male</td>
<td valign="middle" align="right" rowspan="1" colspan="1">101</td>
<td valign="middle" align="right" rowspan="1" colspan="1">59.4</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1"> Female</td>
<td valign="middle" align="right" rowspan="1" colspan="1">69</td>
<td valign="middle" align="right" rowspan="1" colspan="1">40.5</td>
</tr>
<tr><td colspan="3" valign="middle" align="left" rowspan="1">Education</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1"> Junior middle school of below</td>
<td valign="middle" align="right" rowspan="1" colspan="1">11</td>
<td valign="middle" align="right" rowspan="1" colspan="1">6.5</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1"> Senior middle school</td>
<td valign="middle" align="right" rowspan="1" colspan="1">36</td>
<td valign="middle" align="right" rowspan="1" colspan="1">21.2</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1"> College or above</td>
<td valign="middle" align="right" rowspan="1" colspan="1">123</td>
<td valign="middle" align="right" rowspan="1" colspan="1">72.3</td>
</tr>
<tr><td colspan="3" valign="middle" align="left" rowspan="1">Marital status</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1"> Unmarried</td>
<td valign="middle" align="right" rowspan="1" colspan="1">52</td>
<td valign="middle" align="right" rowspan="1" colspan="1">30.6</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1"> Married</td>
<td valign="middle" align="right" rowspan="1" colspan="1">110</td>
<td valign="middle" align="right" rowspan="1" colspan="1">64.7</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1"> Divorced or widowed</td>
<td valign="middle" align="right" rowspan="1" colspan="1">8</td>
<td valign="middle" align="right" rowspan="1" colspan="1">4.7</td>
</tr>
<tr><td colspan="3" valign="middle" align="left" rowspan="1">Homeplace</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1"> Countryside</td>
<td valign="middle" align="right" rowspan="1" colspan="1">8</td>
<td valign="middle" align="right" rowspan="1" colspan="1">4.7</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1"> County town</td>
<td valign="middle" align="right" rowspan="1" colspan="1">10</td>
<td valign="middle" align="right" rowspan="1" colspan="1">5.9</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1"> Urban area</td>
<td valign="middle" align="right" rowspan="1" colspan="1">152</td>
<td valign="middle" align="right" rowspan="1" colspan="1">89.4</td>
</tr>
<tr><td colspan="3" valign="middle" align="left" rowspan="1">Monthly income</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1"> <5000 yuan</td>
<td valign="middle" align="right" rowspan="1" colspan="1">31</td>
<td valign="middle" align="right" rowspan="1" colspan="1">18.2</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1"> 5000–8000 yuan</td>
<td valign="middle" align="right" rowspan="1" colspan="1">120</td>
<td valign="middle" align="right" rowspan="1" colspan="1">70.6</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1"> >8000 yuan</td>
<td valign="middle" align="right" rowspan="1" colspan="1">19</td>
<td valign="middle" align="right" rowspan="1" colspan="1">11.2</td>
</tr>
<tr><td colspan="3" valign="middle" align="left" rowspan="1">Identity</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1"> Mild patients</td>
<td valign="middle" align="right" rowspan="1" colspan="1">18</td>
<td valign="middle" align="right" rowspan="1" colspan="1">10.6</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1"> Suspected case</td>
<td valign="middle" align="right" rowspan="1" colspan="1">32</td>
<td valign="middle" align="right" rowspan="1" colspan="1">18.8</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1"> People in close contact with 2019-nCoV pneumonia patients</td>
<td valign="middle" align="right" rowspan="1" colspan="1">70</td>
<td valign="middle" align="right" rowspan="1" colspan="1">41.2</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1"> People who may be exposed to a virus positive environment</td>
<td valign="middle" align="right" rowspan="1" colspan="1">50</td>
<td valign="middle" align="right" rowspan="1" colspan="1">29.4</td>
</tr>
<tr><td colspan="3" valign="middle" align="left" rowspan="1">Fever</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1"> Yes</td>
<td valign="middle" align="right" rowspan="1" colspan="1">23</td>
<td valign="middle" align="right" rowspan="1" colspan="1">13.5</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1"> No</td>
<td valign="middle" align="right" rowspan="1" colspan="1">147</td>
<td valign="middle" align="right" rowspan="1" colspan="1">86.5</td>
</tr>
<tr><td colspan="3" valign="middle" align="left" rowspan="1">Respiratory symptoms</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1"> Yes</td>
<td valign="middle" align="right" rowspan="1" colspan="1">56</td>
<td valign="middle" align="right" rowspan="1" colspan="1">32.9</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1"> No</td>
<td valign="middle" align="right" rowspan="1" colspan="1">114</td>
<td valign="middle" align="right" rowspan="1" colspan="1">67.1</td>
</tr>
</tbody>
</table>
</table-wrap>
<table-wrap id="t2-medscimonit-26-e923921" position="float"><label>Table 2</label>
<caption><p>The correlations among participants’ social capital (PSCI-16), stress (SASR), anxiety (SAS) and sleep quality (PSQI).</p>
</caption>
<table frame="hsides" rules="rows"><thead><tr><th valign="middle" align="center" rowspan="1" colspan="1"></th>
<th valign="middle" align="center" rowspan="1" colspan="1">Mean</th>
<th valign="middle" align="center" rowspan="1" colspan="1">Std. deviation</th>
<th valign="middle" align="center" rowspan="1" colspan="1">PSCI-16</th>
<th valign="middle" align="center" rowspan="1" colspan="1">SAS</th>
<th valign="middle" align="center" rowspan="1" colspan="1">SASR</th>
<th valign="middle" align="center" rowspan="1" colspan="1">PSQI</th>
</tr>
</thead>
<tbody><tr><td valign="middle" align="left" rowspan="1" colspan="1">PSCI-16</td>
<td valign="middle" align="right" rowspan="1" colspan="1">48.735</td>
<td valign="middle" align="right" rowspan="1" colspan="1">15.211</td>
<td valign="middle" align="center" rowspan="1" colspan="1">1</td>
<td valign="middle" align="center" rowspan="1" colspan="1"></td>
<td valign="middle" align="center" rowspan="1" colspan="1"></td>
<td valign="middle" align="center" rowspan="1" colspan="1"></td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1">SAS</td>
<td valign="middle" align="right" rowspan="1" colspan="1">55.382</td>
<td valign="middle" align="right" rowspan="1" colspan="1">14.291</td>
<td valign="middle" align="center" rowspan="1" colspan="1">.619<xref ref-type="table-fn" rid="tfn1-medscimonit-26-e923921">**</xref>
</td>
<td valign="middle" align="center" rowspan="1" colspan="1">1</td>
<td valign="middle" align="center" rowspan="1" colspan="1"></td>
<td valign="middle" align="center" rowspan="1" colspan="1"></td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1">SASR</td>
<td valign="middle" align="right" rowspan="1" colspan="1">77.488</td>
<td valign="middle" align="right" rowspan="1" colspan="1">30.234</td>
<td valign="middle" align="center" rowspan="1" colspan="1">.543<xref ref-type="table-fn" rid="tfn1-medscimonit-26-e923921">**</xref>
</td>
<td valign="middle" align="center" rowspan="1" colspan="1">.553<xref ref-type="table-fn" rid="tfn1-medscimonit-26-e923921">**</xref>
</td>
<td valign="middle" align="center" rowspan="1" colspan="1">1</td>
<td valign="middle" align="center" rowspan="1" colspan="1"></td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1">PSQI</td>
<td valign="middle" align="right" rowspan="1" colspan="1">8.482</td>
<td valign="middle" align="right" rowspan="1" colspan="1">4.646</td>
<td valign="middle" align="center" rowspan="1" colspan="1">.479<xref ref-type="table-fn" rid="tfn1-medscimonit-26-e923921">**</xref>
</td>
<td valign="middle" align="center" rowspan="1" colspan="1">.523<xref ref-type="table-fn" rid="tfn1-medscimonit-26-e923921">**</xref>
</td>
<td valign="middle" align="center" rowspan="1" colspan="1">.628<xref ref-type="table-fn" rid="tfn1-medscimonit-26-e923921">**</xref>
</td>
<td valign="middle" align="center" rowspan="1" colspan="1">1</td>
</tr>
</tbody>
</table>
<table-wrap-foot><fn id="tfn1-medscimonit-26-e923921"><label>**</label>
<p>P<0.01.</p>
</fn>
<fn id="tfn2-medscimonit-26-e923921"><p>All the data in the form indicates the score of the questionnaire.</p>
</fn>
</table-wrap-foot>
</table-wrap>
<table-wrap id="t3-medscimonit-26-e923921" position="float"><label>Table 3</label>
<caption><p>Normalized path coefficient.</p>
</caption>
<table frame="hsides" rules="rows"><thead><tr><th valign="middle" align="center" rowspan="1" colspan="1">Path</th>
<th valign="middle" align="center" rowspan="1" colspan="1">Standardization coefficient</th>
<th valign="middle" align="center" rowspan="1" colspan="1">Unstandardized coefficients</th>
<th valign="middle" align="center" rowspan="1" colspan="1">S.E.</th>
<th valign="middle" align="center" rowspan="1" colspan="1">C.R.</th>
<th valign="middle" align="center" rowspan="1" colspan="1">P</th>
</tr>
</thead>
<tbody><tr><td valign="middle" align="left" rowspan="1" colspan="1">SAS ← PSCI-16</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.619</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.581</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.057</td>
<td valign="middle" align="right" rowspan="1" colspan="1">10.238</td>
<td valign="middle" align="center" rowspan="1" colspan="1"><xref ref-type="table-fn" rid="tfn3-medscimonit-26-e923921">***</xref>
</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1">SASR ← SAS</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.351</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.742</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.164</td>
<td valign="middle" align="right" rowspan="1" colspan="1">4.514</td>
<td valign="middle" align="center" rowspan="1" colspan="1"><xref ref-type="table-fn" rid="tfn3-medscimonit-26-e923921">***</xref>
</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1">SASR ← PSCI-16</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.327</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.649</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.154</td>
<td valign="middle" align="right" rowspan="1" colspan="1">4.205</td>
<td valign="middle" align="center" rowspan="1" colspan="1"><xref ref-type="table-fn" rid="tfn3-medscimonit-26-e923921">***</xref>
</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1">PSQI ← SASR</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.488</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.075</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.011</td>
<td valign="middle" align="right" rowspan="1" colspan="1">7.052</td>
<td valign="middle" align="center" rowspan="1" colspan="1"><xref ref-type="table-fn" rid="tfn3-medscimonit-26-e923921">***</xref>
</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1">PSQI ← SAS</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.253</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.082</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.022</td>
<td valign="middle" align="right" rowspan="1" colspan="1">3.658</td>
<td valign="middle" align="center" rowspan="1" colspan="1"><xref ref-type="table-fn" rid="tfn3-medscimonit-26-e923921">***</xref>
</td>
</tr>
</tbody>
</table>
<table-wrap-foot><fn id="tfn3-medscimonit-26-e923921"><label>***</label>
<p>P<0.001.</p>
</fn>
<fn id="tfn4-medscimonit-26-e923921"><p>All the data in the form indicates the score of the questionnaire.</p>
</fn>
</table-wrap-foot>
</table-wrap>
<table-wrap id="t4-medscimonit-26-e923921" position="float"><label>Table 4</label>
<caption><p>Result of Bootstrap indirect effects analysis.</p>
</caption>
<table frame="hsides" rules="rows"><thead><tr><th valign="middle" rowspan="2" align="center" colspan="1">Mediation effect path</th>
<th valign="middle" rowspan="2" align="center" colspan="1">Standardization coefficient</th>
<th valign="middle" rowspan="2" align="center" colspan="1">Unstandardized coefficients</th>
<th valign="middle" rowspan="2" align="center" colspan="1">Standard error</th>
<th colspan="2" valign="middle" align="center" rowspan="1">95% CI</th>
<th valign="middle" rowspan="2" align="center" colspan="1">P</th>
</tr>
<tr><th valign="middle" align="center" rowspan="1" colspan="1">Lower</th>
<th valign="middle" align="center" rowspan="1" colspan="1">Upper</th>
</tr>
</thead>
<tbody><tr><td valign="middle" align="left" rowspan="1" colspan="1">PSCI-16 → SAS → PSQI</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.157</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.048</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.016</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.019</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.080</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.002</td>
</tr>
<tr><td valign="middle" align="left" rowspan="1" colspan="1">PSCI-16 → SASR → PSQI</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.159</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.049</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.013</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.026</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.076</td>
<td valign="middle" align="center" rowspan="1" colspan="1">0.000</td>
</tr>
</tbody>
</table>
</table-wrap>
</floats-group>
</pmc>
</record>
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