DanceTherParkinsonV1, Pmc, Corpus, bibRecord, 000000

Huntington's disease: Dancing in a dish

Identifieur interne : 000000 ( Pmc/Corpus ); suivant : 000001

Huntington's disease: Dancing in a dish

Auteurs : Kejing Zhang ; Fei Yi ; Guang-Hui Liu ; Juan Carlos Izpisua Belmonte

Source :

Cell Research [ 1001-0602 ] ; 2012.

RBID : PMC:3515752

Abstract

In a recent landmark paper, the Huntington's disease (HD) iPSC Consortium reports on the establishment and characterization of a panel of iPSC lines from HD patients, and more importantly, the successful modeling of HD in vitro. In the same issue of Cell Stem Cell, An et al. reports on the successful targeted gene correction of HD in human iPSCs. Both advances are exciting, provide new resources for current and future HD research, and uncover new challenges to better understand and, most importantly, treat this devastating disease in the near future.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515752

DOI: 10.1038/cr.2012.116
PubMed: 22868272
PubMed Central: 3515752

Links to Exploration step

PMC:3515752

Le document en format XML

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<author><name sortKey="Zhang, Kejing" sort="Zhang, Kejing" uniqKey="Zhang K" first="Kejing" last="Zhang">Kejing Zhang</name>
<affiliation><nlm:aff id="aff1"><institution>Gene Expression Laboratory, Salk Institute for Biological Studies</institution>
, 10010 North Torrey Pines Road, La Jolla, CA 92037,<country>USA</country>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Yi, Fei" sort="Yi, Fei" uniqKey="Yi F" first="Fei" last="Yi">Fei Yi</name>
<affiliation><nlm:aff id="aff1"><institution>Gene Expression Laboratory, Salk Institute for Biological Studies</institution>
, 10010 North Torrey Pines Road, La Jolla, CA 92037,<country>USA</country>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Liu, Guang Hui" sort="Liu, Guang Hui" uniqKey="Liu G" first="Guang-Hui" last="Liu">Guang-Hui Liu</name>
<affiliation><nlm:aff id="aff1"><institution>Gene Expression Laboratory, Salk Institute for Biological Studies</institution>
, 10010 North Torrey Pines Road, La Jolla, CA 92037,<country>USA</country>
</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff2"><institution>National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences</institution>
, Beijing 100101,<country>China</country>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Belmonte, Juan Carlos Izpisua" sort="Belmonte, Juan Carlos Izpisua" uniqKey="Belmonte J" first="Juan Carlos Izpisua" last="Belmonte">Juan Carlos Izpisua Belmonte</name>
<affiliation><nlm:aff id="aff1"><institution>Gene Expression Laboratory, Salk Institute for Biological Studies</institution>
, 10010 North Torrey Pines Road, La Jolla, CA 92037,<country>USA</country>
</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff3"><institution>Center for Regenerative Medicine in Barcelona</institution>
, Dr. Aiguader 88, 08003 Barcelona,<country>Spain</country>
</nlm:aff>
</affiliation>
</author>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Huntington's disease: Dancing in a dish</title>
<author><name sortKey="Zhang, Kejing" sort="Zhang, Kejing" uniqKey="Zhang K" first="Kejing" last="Zhang">Kejing Zhang</name>
<affiliation><nlm:aff id="aff1"><institution>Gene Expression Laboratory, Salk Institute for Biological Studies</institution>
, 10010 North Torrey Pines Road, La Jolla, CA 92037,<country>USA</country>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Yi, Fei" sort="Yi, Fei" uniqKey="Yi F" first="Fei" last="Yi">Fei Yi</name>
<affiliation><nlm:aff id="aff1"><institution>Gene Expression Laboratory, Salk Institute for Biological Studies</institution>
, 10010 North Torrey Pines Road, La Jolla, CA 92037,<country>USA</country>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Liu, Guang Hui" sort="Liu, Guang Hui" uniqKey="Liu G" first="Guang-Hui" last="Liu">Guang-Hui Liu</name>
<affiliation><nlm:aff id="aff1"><institution>Gene Expression Laboratory, Salk Institute for Biological Studies</institution>
, 10010 North Torrey Pines Road, La Jolla, CA 92037,<country>USA</country>
</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff2"><institution>National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences</institution>
, Beijing 100101,<country>China</country>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Belmonte, Juan Carlos Izpisua" sort="Belmonte, Juan Carlos Izpisua" uniqKey="Belmonte J" first="Juan Carlos Izpisua" last="Belmonte">Juan Carlos Izpisua Belmonte</name>
<affiliation><nlm:aff id="aff1"><institution>Gene Expression Laboratory, Salk Institute for Biological Studies</institution>
, 10010 North Torrey Pines Road, La Jolla, CA 92037,<country>USA</country>
</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff3"><institution>Center for Regenerative Medicine in Barcelona</institution>
, Dr. Aiguader 88, 08003 Barcelona,<country>Spain</country>
</nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Cell Research</title>
<idno type="ISSN">1001-0602</idno>
<idno type="eISSN">1748-7838</idno>
<imprint><date when="2012">2012</date>
</imprint>
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<front><div type="abstract" xml:lang="en"><p>In a recent landmark paper, the Huntington's disease (HD) iPSC Consortium reports on the establishment and characterization of a panel of iPSC lines from HD patients, and more importantly, the successful modeling of HD <italic>in vitro</italic>
. In the same issue of <italic>Cell Stem Cell</italic>
, An <italic>et al</italic>
. reports on the successful targeted gene correction of HD in human iPSCs. Both advances are exciting, provide new resources for current and future HD research, and uncover new challenges to better understand and, most importantly, treat this devastating disease in the near future.</p>
</div>
</front>
</TEI>
<pmc article-type="other"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
  <front><journal-meta><journal-id journal-id-type="nlm-ta">Cell Res</journal-id>
<journal-id journal-id-type="iso-abbrev">Cell Res</journal-id>
<journal-title-group><journal-title>Cell Research</journal-title>
</journal-title-group>
<issn pub-type="ppub">1001-0602</issn>
<issn pub-type="epub">1748-7838</issn>
<publisher><publisher-name>Nature Publishing Group</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">22868272</article-id>
<article-id pub-id-type="pmc">3515752</article-id>
<article-id pub-id-type="pii">cr2012116</article-id>
<article-id pub-id-type="doi">10.1038/cr.2012.116</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Research Highlight</subject>
</subj-group>
</article-categories>
<title-group><article-title>Huntington's disease: Dancing in a dish</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Zhang</surname>
<given-names>Kejing</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
<xref ref-type="author-notes" rid="note1"><sup>*</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Yi</surname>
<given-names>Fei</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
<xref ref-type="author-notes" rid="note1"><sup>*</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Liu</surname>
<given-names>Guang-Hui</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
<xref ref-type="aff" rid="aff2">2</xref>
<xref ref-type="corresp" rid="caf1">*</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Belmonte</surname>
<given-names>Juan Carlos Izpisua</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
<xref ref-type="aff" rid="aff3">3</xref>
<xref ref-type="corresp" rid="caf2">*</xref>
</contrib>
<aff id="aff1"><label>1</label>
<institution>Gene Expression Laboratory, Salk Institute for Biological Studies</institution>
, 10010 North Torrey Pines Road, La Jolla, CA 92037,<country>USA</country>
</aff>
<aff id="aff2"><label>2</label>
<institution>National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences</institution>
, Beijing 100101,<country>China</country>
</aff>
<aff id="aff3"><label>3</label>
<institution>Center for Regenerative Medicine in Barcelona</institution>
, Dr. Aiguader 88, 08003 Barcelona,<country>Spain</country>
</aff>
</contrib-group>
<author-notes><corresp id="caf1"><label>*</label>
E-mail: <email>ghliu@ibp.ac.cn</email>
</corresp>
<corresp id="caf2"><label>*</label>
E-mail: <email>belmonte@salk.edu</email>
, <email>izpisua@cmrb.eu</email>
</corresp>
<fn fn-type="present-address" id="note1"><label>*</label>
<p>These two authors contributed equally to this work.</p>
</fn>
</author-notes>
<pub-date pub-type="ppub"><month>12</month>
<year>2012</year>
</pub-date>
<pub-date pub-type="epub"><day>07</day>
<month>08</month>
<year>2012</year>
</pub-date>
<volume>22</volume>
<issue>12</issue>
<fpage>1627</fpage>
<lpage>1630</lpage>
<permissions><copyright-statement>Copyright © 2012 Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences</copyright-statement>
<copyright-year>2012</copyright-year>
<copyright-holder>Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences</copyright-holder>
</permissions>
<abstract abstract-type="summary"><p>In a recent landmark paper, the Huntington's disease (HD) iPSC Consortium reports on the establishment and characterization of a panel of iPSC lines from HD patients, and more importantly, the successful modeling of HD <italic>in vitro</italic>
. In the same issue of <italic>Cell Stem Cell</italic>
, An <italic>et al</italic>
. reports on the successful targeted gene correction of HD in human iPSCs. Both advances are exciting, provide new resources for current and future HD research, and uncover new challenges to better understand and, most importantly, treat this devastating disease in the near future.</p>
</abstract>
</article-meta>
</front>
</pmc>
</record>

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Huntington's disease: Dancing in a dish

Huntington's disease: Dancing in a dish

Source :

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki