Dynamic High-Cadence Cycling Improves Motor Symptoms in Parkinson’s Disease
Identifieur interne : 000025 ( Pmc/Checkpoint ); précédent : 000024; suivant : 000026Dynamic High-Cadence Cycling Improves Motor Symptoms in Parkinson’s Disease
Auteurs : Angela L. Ridgel [États-Unis] ; Robert S. Phillips [États-Unis] ; Benjamin L. Walter [États-Unis] ; Fred M. Discenzo [États-Unis] ; Kenneth A. Loparo [États-Unis]Source :
- Frontiers in Neurology [ 1664-2295 ] ; 2015.
Abstract
Individuals with Parkinson’s disease (PD) often have deficits in kinesthesia. There is a need for rehabilitation interventions that improve these kinesthetic deficits. Forced (tandem) cycling at a high cadence improves motor function. However, tandem cycling is difficult to implement in a rehabilitation setting.
To construct an instrumented, motored cycle and to examine if high cadence dynamic cycling promotes improvements in motor function.
This motored cycle had two different modes: dynamic and static cycling. In dynamic mode, the motor maintained 75–85 rpm. In static mode, the rider determined the pedaling cadence. UPDRS Motor III and Timed Up and Go (TUG) were used to assess changes in motor function after three cycling sessions.
Individuals in the static group showed a lower cadence but a higher power, torque and heart rate than the dynamic group. UPDRS score showed a significant 13.9% improvement in the dynamic group and only a 0.9% improvement in the static group. There was also a 16.5% improvement in TUG time in the dynamic group but only an 8% improvement in the static group.
These findings show that dynamic cycling can improve PD motor function and that activation of proprioceptors with a high cadence but variable pattern may be important for motor improvements in PD.
Url:
DOI: 10.3389/fneur.2015.00194
PubMed: 26388836
PubMed Central: 4557094
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Phillips</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Exercise Physiology, Kent State University</institution>,<addr-line>Kent, OH</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Walter, Benjamin L" sort="Walter, Benjamin L" uniqKey="Walter B" first="Benjamin L." last="Walter">Benjamin L. Walter</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Movement Disorders Center, University Hospital Cleveland</institution>,<addr-line>Cleveland, OH</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Department of Neurology, Case Western Reserve University</institution>,<addr-line>Cleveland, OH</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Discenzo, Fred M" sort="Discenzo, Fred M" uniqKey="Discenzo F" first="Fred M." last="Discenzo">Fred M. Discenzo</name><affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Department of Industrial Automation, Rockwell Automation</institution>,<addr-line>Mayfield Heights, OH</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Loparo, Kenneth A" sort="Loparo, Kenneth A" uniqKey="Loparo K" first="Kenneth A." last="Loparo">Kenneth A. Loparo</name><affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Department of Electrical Engineering and Computer Science, Case Western Reserve University</institution>,<addr-line>Cleveland, OH</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26388836</idno><idno type="pmc">4557094</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557094</idno><idno type="RBID">PMC:4557094</idno><idno type="doi">10.3389/fneur.2015.00194</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">000010</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000010</idno><idno type="wicri:Area/Pmc/Curation">000010</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000010</idno><idno type="wicri:Area/Pmc/Checkpoint">000025</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000025</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Dynamic High-Cadence Cycling Improves Motor Symptoms in Parkinson’s Disease</title><author><name sortKey="Ridgel, Angela L" sort="Ridgel, Angela L" uniqKey="Ridgel A" first="Angela L." last="Ridgel">Angela L. Ridgel</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Exercise Physiology, Kent State University</institution>,<addr-line>Kent, OH</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Phillips, Robert S" sort="Phillips, Robert S" uniqKey="Phillips R" first="Robert S." last="Phillips">Robert S. Phillips</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Exercise Physiology, Kent State University</institution>,<addr-line>Kent, OH</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Walter, Benjamin L" sort="Walter, Benjamin L" uniqKey="Walter B" first="Benjamin L." last="Walter">Benjamin L. Walter</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Movement Disorders Center, University Hospital Cleveland</institution>,<addr-line>Cleveland, OH</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Department of Neurology, Case Western Reserve University</institution>,<addr-line>Cleveland, OH</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Discenzo, Fred M" sort="Discenzo, Fred M" uniqKey="Discenzo F" first="Fred M." last="Discenzo">Fred M. Discenzo</name><affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Department of Industrial Automation, Rockwell Automation</institution>,<addr-line>Mayfield Heights, OH</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Loparo, Kenneth A" sort="Loparo, Kenneth A" uniqKey="Loparo K" first="Kenneth A." last="Loparo">Kenneth A. Loparo</name><affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Department of Electrical Engineering and Computer Science, Case Western Reserve University</institution>,<addr-line>Cleveland, OH</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Frontiers in Neurology</title><idno type="eISSN">1664-2295</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="ST1"><title>Rationale</title><p>Individuals with Parkinson’s disease (PD) often have deficits in kinesthesia. There is a need for rehabilitation interventions that improve these kinesthetic deficits. Forced (tandem) cycling at a high cadence improves motor function. However, tandem cycling is difficult to implement in a rehabilitation setting.</p></sec><sec id="ST2"><title>Objective</title><p>To construct an instrumented, motored cycle and to examine if high cadence dynamic cycling promotes improvements in motor function.</p></sec><sec id="ST3"><title>Method</title><p>This motored cycle had two different modes: dynamic and static cycling. In dynamic mode, the motor maintained 75–85 rpm. In static mode, the rider determined the pedaling cadence. UPDRS Motor III and Timed Up and Go (TUG) were used to assess changes in motor function after three cycling sessions.</p></sec><sec id="ST4"><title>Results</title><p>Individuals in the static group showed a lower cadence but a higher power, torque and heart rate than the dynamic group. UPDRS score showed a significant 13.9% improvement in the dynamic group and only a 0.9% improvement in the static group. There was also a 16.5% improvement in TUG time in the dynamic group but only an 8% improvement in the static group.</p></sec><sec id="ST5"><title>Conclusion</title><p>These findings show that dynamic cycling can improve PD motor function and that activation of proprioceptors with a high cadence but variable pattern may be important for motor improvements in PD.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Kowal, Sl" uniqKey="Kowal S">SL Kowal</name></author><author><name sortKey="Dall, Tm" uniqKey="Dall T">TM Dall</name></author><author><name sortKey="Chakrabarti, R" uniqKey="Chakrabarti R">R Chakrabarti</name></author><author><name sortKey="Storm, Mv" uniqKey="Storm M">MV Storm</name></author><author><name sortKey="Jain, A" uniqKey="Jain A">A Jain</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ahlskog, Je" uniqKey="Ahlskog J">JE Ahlskog</name></author><author><name sortKey="Muenter, 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<front><journal-meta><journal-id journal-id-type="nlm-ta">Front Neurol</journal-id><journal-id journal-id-type="iso-abbrev">Front Neurol</journal-id><journal-id journal-id-type="publisher-id">Front. Neurol.</journal-id><journal-title-group><journal-title>Frontiers in Neurology</journal-title></journal-title-group><issn pub-type="epub">1664-2295</issn><publisher><publisher-name>Frontiers Media S.A.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">26388836</article-id><article-id pub-id-type="pmc">4557094</article-id><article-id pub-id-type="doi">10.3389/fneur.2015.00194</article-id><article-categories><subj-group subj-group-type="heading"><subject>Neuroscience</subject><subj-group><subject>Original Research</subject></subj-group></subj-group></article-categories><title-group><article-title>Dynamic High-Cadence Cycling Improves Motor Symptoms in Parkinson’s Disease</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Ridgel</surname><given-names>Angela L.</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="corresp" rid="cor1">*</xref><uri xlink:type="simple" xlink:href="http://frontiersin.org/people/u/200201"></uri></contrib><contrib contrib-type="author"><name><surname>Phillips</surname><given-names>Robert S.</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><uri xlink:type="simple" xlink:href="http://frontiersin.org/people/u/258185"></uri></contrib><contrib contrib-type="author"><name><surname>Walter</surname><given-names>Benjamin L.</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref><xref ref-type="aff" rid="aff3"><sup>3</sup></xref></contrib><contrib contrib-type="author"><name><surname>Discenzo</surname><given-names>Fred M.</given-names></name><xref ref-type="aff" rid="aff4"><sup>4</sup></xref><uri xlink:type="simple" xlink:href="http://frontiersin.org/people/u/265090"></uri></contrib><contrib contrib-type="author"><name><surname>Loparo</surname><given-names>Kenneth A.</given-names></name><xref ref-type="aff" rid="aff5"><sup>5</sup></xref><uri xlink:type="simple" xlink:href="http://frontiersin.org/people/u/265117"></uri></contrib></contrib-group><aff id="aff1"><sup>1</sup><institution>Department of Exercise Physiology, Kent State University</institution>,<addr-line>Kent, OH</addr-line>,<country>USA</country></aff><aff id="aff2"><sup>2</sup><institution>Movement Disorders Center, University Hospital Cleveland</institution>,<addr-line>Cleveland, OH</addr-line>,<country>USA</country></aff><aff id="aff3"><sup>3</sup><institution>Department of Neurology, Case Western Reserve University</institution>,<addr-line>Cleveland, OH</addr-line>,<country>USA</country></aff><aff id="aff4"><sup>4</sup><institution>Department of Industrial Automation, Rockwell Automation</institution>,<addr-line>Mayfield Heights, OH</addr-line>,<country>USA</country></aff><aff id="aff5"><sup>5</sup><institution>Department of Electrical Engineering and Computer Science, Case Western Reserve University</institution>,<addr-line>Cleveland, OH</addr-line>,<country>USA</country></aff><author-notes><fn fn-type="edited-by"><p>Edited by: Marta Bienkiewicz, Aix-Marseille University, France</p></fn><fn fn-type="edited-by"><p>Reviewed by: Elizabeth B. Torres, Rutgers University, USA; William Richard Young, Brunel University, UK</p></fn><corresp content-type="corresp" id="cor1">*Correspondence: Angela L. Ridgel, Department of Exercise Physiology, Kent State University, 350 Midway Dr, Kent, OH 44242, USA, <email>aridgel@kent.edu</email></corresp><fn fn-type="other" id="fn001"><p>Specialty section: This article was submitted to Movement Disorders, a section of the journal Frontiers in Neurology</p></fn></author-notes><pub-date pub-type="epub"><day>02</day><month>9</month><year>2015</year></pub-date><pub-date pub-type="collection"><year>2015</year></pub-date><volume>6</volume><elocation-id>194</elocation-id><history><date date-type="received"><day>22</day><month>7</month><year>2015</year></date><date date-type="accepted"><day>20</day><month>8</month><year>2015</year></date></history><permissions><copyright-statement>Copyright © 2015 Ridgel, Phillips, Walter, Discenzo and Loparo.</copyright-statement><copyright-year>2015</copyright-year><copyright-holder>Ridgel, Phillips, Walter, Discenzo and Loparo</copyright-holder><license xlink:href="http://creativecommons.org/licenses/by/4.0/"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</license-p></license></permissions><abstract abstract-type="executive-summary"><sec id="ST1"><title>Rationale</title><p>Individuals with Parkinson’s disease (PD) often have deficits in kinesthesia. There is a need for rehabilitation interventions that improve these kinesthetic deficits. Forced (tandem) cycling at a high cadence improves motor function. However, tandem cycling is difficult to implement in a rehabilitation setting.</p></sec><sec id="ST2"><title>Objective</title><p>To construct an instrumented, motored cycle and to examine if high cadence dynamic cycling promotes improvements in motor function.</p></sec><sec id="ST3"><title>Method</title><p>This motored cycle had two different modes: dynamic and static cycling. In dynamic mode, the motor maintained 75–85 rpm. In static mode, the rider determined the pedaling cadence. UPDRS Motor III and Timed Up and Go (TUG) were used to assess changes in motor function after three cycling sessions.</p></sec><sec id="ST4"><title>Results</title><p>Individuals in the static group showed a lower cadence but a higher power, torque and heart rate than the dynamic group. UPDRS score showed a significant 13.9% improvement in the dynamic group and only a 0.9% improvement in the static group. There was also a 16.5% improvement in TUG time in the dynamic group but only an 8% improvement in the static group.</p></sec><sec id="ST5"><title>Conclusion</title><p>These findings show that dynamic cycling can improve PD motor function and that activation of proprioceptors with a high cadence but variable pattern may be important for motor improvements in PD.</p></sec></abstract><kwd-group><kwd>movement disorders</kwd><kwd>exercise</kwd><kwd>rehabilitation</kwd><kwd>neuroplasticity</kwd><kwd>bradykinesia</kwd><kwd>motor function</kwd></kwd-group><funding-group><award-group><funding-source id="cn01">National Institutes of Health<named-content content-type="fundref-id">10.13039/100000002</named-content></funding-source><award-id rid="cn01">R21 HD068846</award-id></award-group></funding-group><counts><fig-count count="4"></fig-count><table-count count="2"></table-count><equation-count count="0"></equation-count><ref-count count="50"></ref-count><page-count count="8"></page-count><word-count count="6143"></word-count></counts></article-meta></front></pmc><affiliations><list><country><li>États-Unis</li></country></list><tree><country name="États-Unis"><noRegion><name sortKey="Ridgel, Angela L" sort="Ridgel, Angela L" uniqKey="Ridgel A" first="Angela L." last="Ridgel">Angela L. Ridgel</name></noRegion><name sortKey="Discenzo, Fred M" sort="Discenzo, Fred M" uniqKey="Discenzo F" first="Fred M." last="Discenzo">Fred M. Discenzo</name><name sortKey="Loparo, Kenneth A" sort="Loparo, Kenneth A" uniqKey="Loparo K" first="Kenneth A." last="Loparo">Kenneth A. Loparo</name><name sortKey="Phillips, Robert S" sort="Phillips, Robert S" uniqKey="Phillips R" first="Robert S." last="Phillips">Robert S. Phillips</name><name sortKey="Walter, Benjamin L" sort="Walter, Benjamin L" uniqKey="Walter B" first="Benjamin L." last="Walter">Benjamin L. Walter</name><name sortKey="Walter, Benjamin L" sort="Walter, Benjamin L" uniqKey="Walter B" first="Benjamin L." last="Walter">Benjamin L. Walter</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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