Children with obsessive-compulsive disorder: are they just “little adults”?
Identifieur interne : 000035 ( Ncbi/Checkpoint ); précédent : 000034; suivant : 000036Children with obsessive-compulsive disorder: are they just “little adults”?
Auteurs : Simran K. Kalra ; Susan E. SwedoSource :
- The Journal of Clinical Investigation [ 0021-9738 ] ; 2009.
Abstract
Childhood-onset obsessive-compulsive disorder (OCD) affects 1%–2% of children and adolescents. It is characterized by recurrent obsessions and compulsions that create distress and interfere with daily life. The symptoms reported by children are similar to those seen among individuals who develop OCD in adulthood, and the two groups of patients are treated with similar symptom-relieving behavior therapies and medications. However, there are differences in sex ratios, patterns of comorbidity, and the results of neuroimaging studies that might be important. Here we review the diagnosis and treatment of childhood-onset OCD in light of pediatric and adult studies. We also discuss current knowledge of the pathophysiology of the disorder. Despite advances in this area, further research is needed to understand better the etiopathogenesis of the disorder and to develop new, more effective therapeutic options.
Url:
DOI: 10.1172/JCI37563
PubMed: 19339765
PubMed Central: 2662563
Affiliations:
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“little adults”?</title><author><name sortKey="Kalra, Simran K" sort="Kalra, Simran K" uniqKey="Kalra S" first="Simran K." last="Kalra">Simran K. Kalra</name></author><author><name sortKey="Swedo, Susan E" sort="Swedo, Susan E" uniqKey="Swedo S" first="Susan E." last="Swedo">Susan E. Swedo</name></author></analytic><series><title level="j">The Journal of Clinical Investigation</title><idno type="ISSN">0021-9738</idno><idno type="eISSN">1558-8238</idno><imprint><date when="2009">2009</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Childhood-onset obsessive-compulsive disorder (OCD) affects 1%–2% of
children and adolescents. It is characterized by recurrent obsessions and
compulsions that create distress and interfere with daily life. The symptoms
reported by children are similar to those seen among individuals who develop OCD
in adulthood, and the two groups of patients are treated with similar
symptom-relieving behavior therapies and medications. However, there are
differences in sex ratios, patterns of comorbidity, and the results of
neuroimaging studies that might be important. Here we review the diagnosis and
treatment of childhood-onset OCD in light of pediatric and adult studies. We
also discuss current knowledge of the pathophysiology of the disorder. Despite
advances in this area, further research is needed to understand better the
etiopathogenesis of the disorder and to develop new, more effective therapeutic
options.</p></div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Kalra, Simran K" sort="Kalra, Simran K" uniqKey="Kalra S" first="Simran K." last="Kalra">Simran K. Kalra</name><name sortKey="Swedo, Susan E" sort="Swedo, Susan E" uniqKey="Swedo S" first="Susan E." last="Swedo">Susan E. Swedo</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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