Neurologic manifestations of chronic methamphetamine abuse
Identifieur interne : 000201 ( Main/Exploration ); précédent : 000200; suivant : 000202Neurologic manifestations of chronic methamphetamine abuse
Auteurs : Daniel E. RusyniakSource :
- Neurologic clinics [ 0733-8619 ] ; 2011.
Abstract
Chronic methamphetamine abuse has devastating effects on the central nervous system. The degree to which addicts will tolerate the dysfunction in the way they think, feel, move, and even look, is a powerful testimony to the addictive properties of this drug. While the mechanisms behind these disorders are complex, at their heart they involve the recurring increase in the concentrations of central monoamines with subsequent dysfunction in dopaminergic neurotransmission. The mainstay of treatment for the problems associated with chronic methamphetamine abuse is abstinence. However, by recognizing the manifestations of chronic abuse, clinicians will be better able to help their patients get treatment for their addiction and to deal with the neurologic complications related to chronic abuse.
Url:
DOI: 10.1016/j.ncl.2011.05.004
PubMed: 21803215
PubMed Central: 3148451
Affiliations:
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