Late‐onset asymmetric myoclonus: An emerging syndrome
Identifieur interne : 000139 ( Istex/Curation ); précédent : 000138; suivant : 000140Late‐onset asymmetric myoclonus: An emerging syndrome
Auteurs : Petra Katschnig [Royaume-Uni, Autriche] ; João Massano [Royaume-Uni, Portugal] ; Mark J. Edwards [Royaume-Uni] ; Petra Schwingenschuh [Royaume-Uni, Autriche] ; Carla Cordivari [Royaume-Uni] ; Kailash P. Bhatia [Royaume-Uni]Source :
- Movement Disorders [ 0885-3185 ] ; 2011-08-01.
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Abstract
Asymmetric cortical myoclonus is typically thought to be associated with either contralateral cortical structural lesions or degenerative disorders such as corticobasal degeneration when onset is in middle‐aged or aged adults. This view has been challenged after a recent case series brought to light a syndrome of senile‐onset, asymmetric cortical myoclonus not associated with any such identifiable disorders, thus, named “primary progressive myoclonus of aging.” This is rare and no other reports have been published; hence, further such cases need to be highlighted.
Here, we describe 3 patients with some similarities, namely, adult‐onset, asymmetric myoclonus that is most likely to be cortical, with an unremarkable thorough diagnostic workup, but with younger age at onset and longer follow‐up time.
This report expands on previous phenotypical descriptions attempting to further develop and refine this possible diagnostic entity. © 2011 Movement Disorder Society
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DOI: 10.1002/mds.23676
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<front><div type="abstract">Asymmetric cortical myoclonus is typically thought to be associated with either contralateral cortical structural lesions or degenerative disorders such as corticobasal degeneration when onset is in middle‐aged or aged adults. This view has been challenged after a recent case series brought to light a syndrome of senile‐onset, asymmetric cortical myoclonus not associated with any such identifiable disorders, thus, named “primary progressive myoclonus of aging.” This is rare and no other reports have been published; hence, further such cases need to be highlighted.</div>
<div type="abstract">Here, we describe 3 patients with some similarities, namely, adult‐onset, asymmetric myoclonus that is most likely to be cortical, with an unremarkable thorough diagnostic workup, but with younger age at onset and longer follow‐up time.</div>
<div type="abstract">This report expands on previous phenotypical descriptions attempting to further develop and refine this possible diagnostic entity. © 2011 Movement Disorder Society</div>
</front>
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