Normal interhemispheric inhibition in persistent developmental stuttering
Identifieur interne : 000237 ( Istex/Corpus ); précédent : 000236; suivant : 000238Normal interhemispheric inhibition in persistent developmental stuttering
Auteurs : Martin Sommer ; Kathrin Knappmeyer ; Evke Jane Hunter ; Alexander Wolffvon Gudenberg ; Nicole Neef ; Walter PaulusSource :
- Movement Disorders [ 0885-3185 ] ; 2009-04-15.
English descriptors
- KwdEn :
Abstract
Imaging studies suggest a right hemispheric (pre)motor overactivity in patients with persistent developmental stuttering (PDS). The interhemispheric inhibition (IHI) studied with transcranial magnetic stimulation is an established measure of the interplay between right and left motor areas. We assessed IHI in 15 young male adults with PDS and 15 age‐matched fluent‐speaking subjects. We additionally studied the ipsilateral silent period (iSP) duration. We found no significant between‐group difference for IHI or for iSP duration. We conclude that the interplay between the primary motor cortices is normal in patients with PDS. The abnormal right motor and premotor activity observed in functional imaging studies on PDS are not likely to reflect altered primary motor cortex excitability, but are likely to have a different origin. © 2009 Movement Disorder Society
Url:
DOI: 10.1002/mds.22383
Links to Exploration step
ISTEX:202EF5A8F092FA04F01E4A4A364EED1E688EA144Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Normal interhemispheric inhibition in persistent developmental stuttering</title><author><name sortKey="Sommer, Martin" sort="Sommer, Martin" uniqKey="Sommer M" first="Martin" last="Sommer">Martin Sommer</name><affiliation><mods:affiliation>Department of Clinical Neurophysiology, University of Göttingen, Göttingen, Germany</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Clinical Neurophysiology, University of Göttingen, Robert‐Koch‐Str. 40, D‐37075 Göttingen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Knappmeyer, Kathrin" sort="Knappmeyer, Kathrin" uniqKey="Knappmeyer K" first="Kathrin" last="Knappmeyer">Kathrin Knappmeyer</name><affiliation><mods:affiliation>Department of Clinical Neurophysiology, University of Göttingen, Göttingen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Hunter, Evke Jane" sort="Hunter, Evke Jane" uniqKey="Hunter E" first="Evke Jane" last="Hunter">Evke Jane Hunter</name><affiliation><mods:affiliation>Department of Clinical Neurophysiology, University of Göttingen, Göttingen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Gudenberg, Alexander Wolffvon" sort="Gudenberg, Alexander Wolffvon" uniqKey="Gudenberg A" first="Alexander Wolffvon" last="Gudenberg">Alexander Wolffvon Gudenberg</name><affiliation><mods:affiliation>Institut der Kasseler Stottertherapie, Feriendorfstraße 1 34308 Bad Emstal, Germany</mods:affiliation></affiliation></author><author><name sortKey="Neef, Nicole" sort="Neef, Nicole" uniqKey="Neef N" first="Nicole" last="Neef">Nicole Neef</name><affiliation><mods:affiliation>Department of Clinical Neurophysiology, University of Göttingen, Göttingen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Paulus, Walter" sort="Paulus, Walter" uniqKey="Paulus W" first="Walter" last="Paulus">Walter Paulus</name><affiliation><mods:affiliation>Department of Clinical Neurophysiology, University of Göttingen, Göttingen, Germany</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:202EF5A8F092FA04F01E4A4A364EED1E688EA144</idno><date when="2009" year="2009">2009</date><idno type="doi">10.1002/mds.22383</idno><idno type="url">https://api.istex.fr/document/202EF5A8F092FA04F01E4A4A364EED1E688EA144/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000237</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000237</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Normal interhemispheric inhibition in persistent developmental stuttering</title><author><name sortKey="Sommer, Martin" sort="Sommer, Martin" uniqKey="Sommer M" first="Martin" last="Sommer">Martin Sommer</name><affiliation><mods:affiliation>Department of Clinical Neurophysiology, University of Göttingen, Göttingen, Germany</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Clinical Neurophysiology, University of Göttingen, Robert‐Koch‐Str. 40, D‐37075 Göttingen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Knappmeyer, Kathrin" sort="Knappmeyer, Kathrin" uniqKey="Knappmeyer K" first="Kathrin" last="Knappmeyer">Kathrin Knappmeyer</name><affiliation><mods:affiliation>Department of Clinical Neurophysiology, University of Göttingen, Göttingen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Hunter, Evke Jane" sort="Hunter, Evke Jane" uniqKey="Hunter E" first="Evke Jane" last="Hunter">Evke Jane Hunter</name><affiliation><mods:affiliation>Department of Clinical Neurophysiology, University of Göttingen, Göttingen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Gudenberg, Alexander Wolffvon" sort="Gudenberg, Alexander Wolffvon" uniqKey="Gudenberg A" first="Alexander Wolffvon" last="Gudenberg">Alexander Wolffvon Gudenberg</name><affiliation><mods:affiliation>Institut der Kasseler Stottertherapie, Feriendorfstraße 1 34308 Bad Emstal, Germany</mods:affiliation></affiliation></author><author><name sortKey="Neef, Nicole" sort="Neef, Nicole" uniqKey="Neef N" first="Nicole" last="Neef">Nicole Neef</name><affiliation><mods:affiliation>Department of Clinical Neurophysiology, University of Göttingen, Göttingen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Paulus, Walter" sort="Paulus, Walter" uniqKey="Paulus W" first="Walter" last="Paulus">Walter Paulus</name><affiliation><mods:affiliation>Department of Clinical Neurophysiology, University of Göttingen, Göttingen, Germany</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2009-04-15">2009-04-15</date><biblScope unit="volume">24</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="769">769</biblScope><biblScope unit="page" to="773">773</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">202EF5A8F092FA04F01E4A4A364EED1E688EA144</idno><idno type="DOI">10.1002/mds.22383</idno><idno type="ArticleID">MDS22383</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>interhemispheric</term><term>ipsilateral silent period</term><term>persistent developmental stuttering</term><term>transcallosal</term><term>transcranial magnetic stimulation</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Imaging studies suggest a right hemispheric (pre)motor overactivity in patients with persistent developmental stuttering (PDS). The interhemispheric inhibition (IHI) studied with transcranial magnetic stimulation is an established measure of the interplay between right and left motor areas. We assessed IHI in 15 young male adults with PDS and 15 age‐matched fluent‐speaking subjects. We additionally studied the ipsilateral silent period (iSP) duration. We found no significant between‐group difference for IHI or for iSP duration. We conclude that the interplay between the primary motor cortices is normal in patients with PDS. The abnormal right motor and premotor activity observed in functional imaging studies on PDS are not likely to reflect altered primary motor cortex excitability, but are likely to have a different origin. © 2009 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Martin Sommer MD</name><affiliations><json:string>Department of Clinical Neurophysiology, University of Göttingen, Göttingen, Germany</json:string><json:string>Department of Clinical Neurophysiology, University of Göttingen, Robert‐Koch‐Str. 40, D‐37075 Göttingen, Germany</json:string></affiliations></json:item><json:item><name>Kathrin Knappmeyer</name><affiliations><json:string>Department of Clinical Neurophysiology, University of Göttingen, Göttingen, Germany</json:string></affiliations></json:item><json:item><name>Evke Jane Hunter</name><affiliations><json:string>Department of Clinical Neurophysiology, University of Göttingen, Göttingen, Germany</json:string></affiliations></json:item><json:item><name>Alexander Wolffvon Gudenberg MD</name><affiliations><json:string>Institut der Kasseler Stottertherapie, Feriendorfstraße 1 34308 Bad Emstal, Germany</json:string></affiliations></json:item><json:item><name>Nicole Neef SLP</name><affiliations><json:string>Department of Clinical Neurophysiology, University of Göttingen, Göttingen, Germany</json:string></affiliations></json:item><json:item><name>Walter Paulus MD</name><affiliations><json:string>Department of Clinical Neurophysiology, University of Göttingen, Göttingen, Germany</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>persistent developmental stuttering</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>transcranial magnetic stimulation</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>interhemispheric</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>transcallosal</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>ipsilateral silent period</value></json:item></subject><articleId><json:string>MDS22383</json:string></articleId><language><json:string>eng</json:string></language><originalGenre><json:string>article</json:string></originalGenre><abstract>Imaging studies suggest a right hemispheric (pre)motor overactivity in patients with persistent developmental stuttering (PDS). The interhemispheric inhibition (IHI) studied with transcranial magnetic stimulation is an established measure of the interplay between right and left motor areas. We assessed IHI in 15 young male adults with PDS and 15 age‐matched fluent‐speaking subjects. We additionally studied the ipsilateral silent period (iSP) duration. We found no significant between‐group difference for IHI or for iSP duration. We conclude that the interplay between the primary motor cortices is normal in patients with PDS. The abnormal right motor and premotor activity observed in functional imaging studies on PDS are not likely to reflect altered primary motor cortex excitability, but are likely to have a different origin. © 2009 Movement Disorder Society</abstract><qualityIndicators><score>6.512</score><pdfVersion>1.3</pdfVersion><pdfPageSize>612 x 810 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractCharCount>869</abstractCharCount><pdfWordCount>14401</pdfWordCount><pdfCharCount>93409</pdfCharCount><pdfPageCount>24</pdfPageCount><abstractWordCount>126</abstractWordCount></qualityIndicators><title>Normal interhemispheric inhibition in persistent developmental stuttering</title><genre><json:string>article</json:string></genre><host><volume>24</volume><publisherId><json:string>MDS</json:string></publisherId><pages><total>5</total><last>773</last><first>769</first></pages><issn><json:string>0885-3185</json:string></issn><issue>5</issue><subject><json:item><value>Brief Report</value></json:item></subject><genre><json:string>journal</json:string></genre><language><json:string>unknown</json:string></language><eissn><json:string>1531-8257</json:string></eissn><title>Movement Disorders</title><doi><json:string>10.1002/(ISSN)1531-8257</json:string></doi></host><categories><wos><json:string>science</json:string><json:string>clinical neurology</json:string></wos><scienceMetrix><json:string>health sciences</json:string><json:string>clinical medicine</json:string><json:string>neurology & neurosurgery</json:string></scienceMetrix></categories><publicationDate>2009</publicationDate><copyrightDate>2009</copyrightDate><doi><json:string>10.1002/mds.22383</json:string></doi><id>202EF5A8F092FA04F01E4A4A364EED1E688EA144</id><score>0.11360189</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/202EF5A8F092FA04F01E4A4A364EED1E688EA144/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/202EF5A8F092FA04F01E4A4A364EED1E688EA144/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/202EF5A8F092FA04F01E4A4A364EED1E688EA144/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Normal interhemispheric inhibition in persistent developmental stuttering</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><availability><p>Copyright © 2009 Movement Disorder Society</p></availability><date>2009</date></publicationStmt><notesStmt><note type="content">*Potential conflict of interest: None reported.</note><note>DFG (Deutsche Forschungsgemeinschaft) - No. SO 429/2‐1; No. SO 429/2‐2;</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Normal interhemispheric inhibition in persistent developmental stuttering</title><author xml:id="author-1"><persName><forename type="first">Martin</forename><surname>Sommer</surname></persName><roleName type="degree">MD</roleName><affiliation>Department of Clinical Neurophysiology, University of Göttingen, Göttingen, Germany</affiliation><affiliation>Department of Clinical Neurophysiology, University of Göttingen, Robert‐Koch‐Str. 40, D‐37075 Göttingen, Germany</affiliation></author><author xml:id="author-2"><persName><forename type="first">Kathrin</forename><surname>Knappmeyer</surname></persName><affiliation>Department of Clinical Neurophysiology, University of Göttingen, Göttingen, Germany</affiliation></author><author xml:id="author-3"><persName><forename type="first">Evke Jane</forename><surname>Hunter</surname></persName><affiliation>Department of Clinical Neurophysiology, University of Göttingen, Göttingen, Germany</affiliation></author><author xml:id="author-4"><persName><forename type="first">Alexander Wolffvon</forename><surname>Gudenberg</surname></persName><roleName type="degree">MD</roleName><affiliation>Institut der Kasseler Stottertherapie, Feriendorfstraße 1 34308 Bad Emstal, Germany</affiliation></author><author xml:id="author-5"><persName><forename type="first">Nicole</forename><surname>Neef</surname></persName><roleName type="degree">SLP</roleName><affiliation>Department of Clinical Neurophysiology, University of Göttingen, Göttingen, Germany</affiliation></author><author xml:id="author-6"><persName><forename type="first">Walter</forename><surname>Paulus</surname></persName><roleName type="degree">MD</roleName><affiliation>Department of Clinical Neurophysiology, University of Göttingen, Göttingen, Germany</affiliation></author></analytic><monogr><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="pISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><idno type="DOI">10.1002/(ISSN)1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2009-04-15"></date><biblScope unit="volume">24</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="769">769</biblScope><biblScope unit="page" to="773">773</biblScope></imprint></monogr><idno type="istex">202EF5A8F092FA04F01E4A4A364EED1E688EA144</idno><idno type="DOI">10.1002/mds.22383</idno><idno type="ArticleID">MDS22383</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2009</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Imaging studies suggest a right hemispheric (pre)motor overactivity in patients with persistent developmental stuttering (PDS). The interhemispheric inhibition (IHI) studied with transcranial magnetic stimulation is an established measure of the interplay between right and left motor areas. We assessed IHI in 15 young male adults with PDS and 15 age‐matched fluent‐speaking subjects. We additionally studied the ipsilateral silent period (iSP) duration. We found no significant between‐group difference for IHI or for iSP duration. We conclude that the interplay between the primary motor cortices is normal in patients with PDS. The abnormal right motor and premotor activity observed in functional imaging studies on PDS are not likely to reflect altered primary motor cortex excitability, but are likely to have a different origin. © 2009 Movement Disorder Society</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>keywords</head><item><term>persistent developmental stuttering</term></item><item><term>transcranial magnetic stimulation</term></item><item><term>interhemispheric</term></item><item><term>transcallosal</term></item><item><term>ipsilateral silent period</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>article-category</head><item><term>Brief Report</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2008-05-26">Received</change><change when="2008-10-15">Registration</change><change when="2009-04-15">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/202EF5A8F092FA04F01E4A4A364EED1E688EA144/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>Hoboken</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1531-8257</doi><issn type="print">0885-3185</issn><issn type="electronic">1531-8257</issn><idGroup><id type="product" value="MDS"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="MOVEMENT DISORDERS">Movement Disorders</title><title type="subtitle">Official Journal of the Movement Disorder Society</title><title type="short">Mov. Disord.</title></titleGroup></publicationMeta><publicationMeta level="part" position="50"><doi origin="wiley" registered="yes">10.1002/mds.v24:5</doi><numberingGroup><numbering type="journalVolume" number="24">24</numbering><numbering type="journalIssue">5</numbering></numberingGroup><coverDate startDate="2009-04-15">15 April 2009</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="220" status="forIssue"><doi origin="wiley" registered="yes">10.1002/mds.22383</doi><idGroup><id type="unit" value="MDS22383"></id></idGroup><countGroup><count type="pageTotal" number="5"></count></countGroup><titleGroup><title type="articleCategory">Brief Report</title><title type="tocHeading1">Brief Reports</title></titleGroup><copyright ownership="thirdParty">Copyright © 2009 Movement Disorder Society</copyright><eventGroup><event type="manuscriptReceived" date="2008-05-26"></event><event type="manuscriptRevised" date="2008-10-09"></event><event type="manuscriptAccepted" date="2008-10-15"></event><event type="publishedOnlineEarlyUnpaginated" date="2009-02-17"></event><event type="firstOnline" date="2009-02-17"></event><event type="publishedOnlineFinalForm" date="2009-04-24"></event><event type="xmlConverted" agent="Converter:JWSART34_TO_WML3G version:2.3.2 mode:FullText source:FullText result:FullText" date="2010-03-09"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-02-02"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-31"></event></eventGroup><numberingGroup><numbering type="pageFirst">769</numbering><numbering type="pageLast">773</numbering></numberingGroup><correspondenceTo>Department of Clinical Neurophysiology, University of Göttingen, Robert‐Koch‐Str. 40, D‐37075 Göttingen, Germany</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:MDS.MDS22383.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="2"></count><count type="tableTotal" number="0"></count><count type="referenceTotal" number="28"></count><count type="wordTotal" number="2912"></count></countGroup><titleGroup><title type="main" xml:lang="en">Normal interhemispheric inhibition in persistent developmental stuttering<link href="#fn1"></link></title><title type="short" xml:lang="en">Interhemispheric Inhibition in Stuttering</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1" corresponding="yes"><personName><givenNames>Martin</givenNames><familyName>Sommer</familyName><degrees>MD</degrees></personName><contactDetails><email normalForm="wpaulus@med.uni-goettingen.de">wpaulus@med.uni‐goettingen.de</email></contactDetails></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Kathrin</givenNames><familyName>Knappmeyer</familyName></personName></creator><creator xml:id="au3" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Evke Jane</givenNames><familyName>Hunter</familyName></personName></creator><creator xml:id="au4" creatorRole="author" affiliationRef="#af2"><personName><givenNames>Alexander Wolffvon</givenNames><familyName>Gudenberg</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au5" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Nicole</givenNames><familyName>Neef</familyName><degrees>SLP</degrees></personName></creator><creator xml:id="au6" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Walter</givenNames><familyName>Paulus</familyName><degrees>MD</degrees></personName></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="DE" type="organization"><unparsedAffiliation>Department of Clinical Neurophysiology, University of Göttingen, Göttingen, Germany</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="DE" type="organization"><unparsedAffiliation>Institut der Kasseler Stottertherapie, Feriendorfstraße 1 34308 Bad Emstal, Germany</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">persistent developmental stuttering</keyword><keyword xml:id="kwd2">transcranial magnetic stimulation</keyword><keyword xml:id="kwd3">interhemispheric</keyword><keyword xml:id="kwd4">transcallosal</keyword><keyword xml:id="kwd5">ipsilateral silent period</keyword></keywordGroup><fundingInfo><fundingAgency>DFG (Deutsche Forschungsgemeinschaft)</fundingAgency><fundingNumber>SO 429/2‐1</fundingNumber><fundingNumber>SO 429/2‐2</fundingNumber></fundingInfo><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>Imaging studies suggest a right hemispheric (pre)motor overactivity in patients with persistent developmental stuttering (PDS). The interhemispheric inhibition (IHI) studied with transcranial magnetic stimulation is an established measure of the interplay between right and left motor areas. We assessed IHI in 15 young male adults with PDS and 15 age‐matched fluent‐speaking subjects. We additionally studied the ipsilateral silent period (iSP) duration. We found no significant between‐group difference for IHI or for iSP duration. We conclude that the interplay between the primary motor cortices is normal in patients with PDS. The abnormal right motor and premotor activity observed in functional imaging studies on PDS are not likely to reflect altered primary motor cortex excitability, but are likely to have a different origin. © 2009 Movement Disorder Society</p></abstract></abstractGroup></contentMeta><noteGroup><note xml:id="fn1"><p>Potential conflict of interest: None reported.</p></note></noteGroup></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Normal interhemispheric inhibition in persistent developmental stuttering</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Interhemispheric Inhibition in Stuttering</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Normal interhemispheric inhibition in persistent developmental stuttering</title></titleInfo><name type="personal"><namePart type="given">Martin</namePart><namePart type="family">Sommer</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Clinical Neurophysiology, University of Göttingen, Göttingen, Germany</affiliation><affiliation>Department of Clinical Neurophysiology, University of Göttingen, Robert‐Koch‐Str. 40, D‐37075 Göttingen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Kathrin</namePart><namePart type="family">Knappmeyer</namePart><affiliation>Department of Clinical Neurophysiology, University of Göttingen, Göttingen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Evke Jane</namePart><namePart type="family">Hunter</namePart><affiliation>Department of Clinical Neurophysiology, University of Göttingen, Göttingen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Alexander Wolffvon</namePart><namePart type="family">Gudenberg</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Institut der Kasseler Stottertherapie, Feriendorfstraße 1 34308 Bad Emstal, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Nicole</namePart><namePart type="family">Neef</namePart><namePart type="termsOfAddress">SLP</namePart><affiliation>Department of Clinical Neurophysiology, University of Göttingen, Göttingen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Walter</namePart><namePart type="family">Paulus</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Clinical Neurophysiology, University of Göttingen, Göttingen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2009-04-15</dateIssued><dateCaptured encoding="w3cdtf">2008-05-26</dateCaptured><dateValid encoding="w3cdtf">2008-10-15</dateValid><copyrightDate encoding="w3cdtf">2009</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">2</extent><extent unit="references">28</extent><extent unit="words">2912</extent></physicalDescription><abstract lang="en">Imaging studies suggest a right hemispheric (pre)motor overactivity in patients with persistent developmental stuttering (PDS). The interhemispheric inhibition (IHI) studied with transcranial magnetic stimulation is an established measure of the interplay between right and left motor areas. We assessed IHI in 15 young male adults with PDS and 15 age‐matched fluent‐speaking subjects. We additionally studied the ipsilateral silent period (iSP) duration. We found no significant between‐group difference for IHI or for iSP duration. We conclude that the interplay between the primary motor cortices is normal in patients with PDS. The abnormal right motor and premotor activity observed in functional imaging studies on PDS are not likely to reflect altered primary motor cortex excitability, but are likely to have a different origin. © 2009 Movement Disorder Society</abstract><note type="content">*Potential conflict of interest: None reported.</note><note type="funding">DFG (Deutsche Forschungsgemeinschaft) - No. SO 429/2‐1; No. SO 429/2‐2; </note><subject lang="en"><genre>keywords</genre><topic>persistent developmental stuttering</topic><topic>transcranial magnetic stimulation</topic><topic>interhemispheric</topic><topic>transcallosal</topic><topic>ipsilateral silent period</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><genre type="journal">journal</genre><subject><genre>article-category</genre><topic>Brief Report</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>24</number></detail><detail type="issue"><caption>no.</caption><number>5</number></detail><extent unit="pages"><start>769</start><end>773</end><total>5</total></extent></part></relatedItem><identifier type="istex">202EF5A8F092FA04F01E4A4A364EED1E688EA144</identifier><identifier type="DOI">10.1002/mds.22383</identifier><identifier type="ArticleID">MDS22383</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2009 Movement Disorder Society</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Psychologie/explor/DanceTherParkinsonV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000237 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 000237 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Psychologie
|area= DanceTherParkinsonV1
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:202EF5A8F092FA04F01E4A4A364EED1E688EA144
|texte= Normal interhemispheric inhibition in persistent developmental stuttering
}}
| This area was generated with Dilib version V0.6.35. |  |