Response of Volta children to jet inoculation of combined live measles, smallpox and yellow fever vaccines
Identifieur interne : 000F31 ( Main/Merge ); précédent : 000F30; suivant : 000F32Response of Volta children to jet inoculation of combined live measles, smallpox and yellow fever vaccines
Auteurs : Harry M. Meyer ; Daniel D. Hostetler ; Barbara C. Bernheim ; Nancy G. Rogers ; Paul Lambin ; Albert Chassary ; René Labusquière ; Joseph E. SmadelSource :
- Bulletin of the World Health Organization [ 0042-9686 ] ; 1964.
Abstract
An earlier study established that Upper Volta children respond to vaccination with the Enders live attenuated measles strain in the same general fashion as do children in the USA. The present report describes a second pilot project carried out in Ouagadougou, Upper Volta. During this investigation various mixtures of live measles, smallpox and 17D yellow fever vaccines were introduced into susceptible infants by jet injection. Combining the attenuated virus vaccines did not alter or accentuate the characteristic clinical reactions elicited by the individual components, nor was there evidence of significant immunological interference. From this experience it is concluded that combined vaccination with these agents may be safely and effectively employed in larger programmes as the need dictates.
Url:
PubMed: 14215185
PubMed Central: 2555088
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PMC:2555088Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>An earlier study established that Upper Volta children respond to vaccination with the Enders live attenuated measles strain in the same general fashion as do children in the USA. The present report describes a second pilot project carried out in Ouagadougou, Upper Volta. During this investigation various mixtures of live measles, smallpox and 17D yellow fever vaccines were introduced into susceptible infants by jet injection. Combining the attenuated virus vaccines did not alter or accentuate the characteristic clinical reactions elicited by the individual components, nor was there evidence of significant immunological interference. From this experience it is concluded that combined vaccination with these agents may be safely and effectively employed in larger programmes as the need dictates.</p>
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