Central Nervous System Prostaglandins and Ethanol
Identifieur interne : 000B78 ( Main/Merge ); précédent : 000B77; suivant : 000B79Central Nervous System Prostaglandins and Ethanol
Auteurs : Raymond F. Anton [États-Unis] ; Carrie L. Randall [États-Unis]Source :
- Alcoholism: Clinical and Experimental Research [ 0145-6008 ] ; 1987-02.
English descriptors
- Teeft :
- Acute ethanol, Alcohol clin, Anton, Arachidonic, Arachidonic acid, Basal levels, Biochem, Brain homogenates, Brain prostaglandin production, Brain synaptosomes, Brain tissue, Cerebral cortex, Chronic ethanol, Clin, Cyclooxygenase, Endogenous, Ethanol, Free arachidonic acid, Functional importance, Functional significance, Microwave, Mouse brain, Neurochem, Neuronal, Neuronal cells, Neuronal tissue, Neurotransmitter, Norepinephrine, Norepinephrine release, Pgd2, Pge2, Pgf2, Pharmacol, Pharmacol biochem behav, Plasma donors, Proc natl acad, Prostaglandin, Prostaglandin synthesis, Public health, Randall, Receptor, Routine antibody testing, Synaptosomal, Synaptosomes, Thromboxane, Txb2, Vascular tissue.
Abstract
There is growing interest in the effect of ethanol on cellular membranes, generally, and neuronal membrane systems, in particular. Perturbations of membranes have led to numerous enzymatically mediated processes, one of which is prostaglandin production. This paper reviews the nature and role of prostaglandins in the central nervous system, and what is known about the effect of ethanol on prostaglandin production in brain. Areas of central nervous system physiological function in which prostaglandins may mediate the actions of ethanol are discussed. Methodological considerations and future directions for research in the area of ethanol and prostaglandins are highlighted.
Url:
DOI: 10.1111/j.1530-0277.1987.tb01251.x
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ISTEX:0173D7C7AA6D1A6D77907F342DC922CAE6C3E451Le document en format XML
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<sourceDesc><biblStruct><analytic><title level="a" type="main">Central Nervous System Prostaglandins and Ethanol</title>
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<wicri:cityArea>Veterans Administration Medical Center and Medical University of South Carolina, Charleston</wicri:cityArea>
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<term>Alcohol clin</term>
<term>Anton</term>
<term>Arachidonic</term>
<term>Arachidonic acid</term>
<term>Basal levels</term>
<term>Biochem</term>
<term>Brain homogenates</term>
<term>Brain prostaglandin production</term>
<term>Brain synaptosomes</term>
<term>Brain tissue</term>
<term>Cerebral cortex</term>
<term>Chronic ethanol</term>
<term>Clin</term>
<term>Cyclooxygenase</term>
<term>Endogenous</term>
<term>Ethanol</term>
<term>Free arachidonic acid</term>
<term>Functional importance</term>
<term>Functional significance</term>
<term>Microwave</term>
<term>Mouse brain</term>
<term>Neurochem</term>
<term>Neuronal</term>
<term>Neuronal cells</term>
<term>Neuronal tissue</term>
<term>Neurotransmitter</term>
<term>Norepinephrine</term>
<term>Norepinephrine release</term>
<term>Pgd2</term>
<term>Pge2</term>
<term>Pgf2</term>
<term>Pharmacol</term>
<term>Pharmacol biochem behav</term>
<term>Plasma donors</term>
<term>Proc natl acad</term>
<term>Prostaglandin</term>
<term>Prostaglandin synthesis</term>
<term>Public health</term>
<term>Randall</term>
<term>Receptor</term>
<term>Routine antibody testing</term>
<term>Synaptosomal</term>
<term>Synaptosomes</term>
<term>Thromboxane</term>
<term>Txb2</term>
<term>Vascular tissue</term>
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<front><div type="abstract" xml:lang="en">There is growing interest in the effect of ethanol on cellular membranes, generally, and neuronal membrane systems, in particular. Perturbations of membranes have led to numerous enzymatically mediated processes, one of which is prostaglandin production. This paper reviews the nature and role of prostaglandins in the central nervous system, and what is known about the effect of ethanol on prostaglandin production in brain. Areas of central nervous system physiological function in which prostaglandins may mediate the actions of ethanol are discussed. Methodological considerations and future directions for research in the area of ethanol and prostaglandins are highlighted.</div>
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