Orexins/hypocretins and aminergic systems
Identifieur interne : 000254 ( Main/Exploration ); précédent : 000253; suivant : 000255Orexins/hypocretins and aminergic systems
Auteurs : K. S. Eriksson ; O. A. Sergeeva [Allemagne] ; H. L. Haas [Allemagne] ; O. Selbach [Allemagne]Source :
- Acta Physiologica [ 1748-1708 ] ; 2010-03.
English descriptors
- Teeft :
- Acta, Acta physiol, Agonist, Amine, Aminergic, Authors journal compilation, Bayer, Behavioural, Behavioural state, Biogenic, Biogenic amines, Boehmer, Bubser, Burdakov, Cholinergic, Comp neurol, Cortical activation, Dentate gyrus, Deutch bubser, Dopamine, Dopaminergic, Dorsal, Dynorphin, Eggermann, Environmental challenges, Eriksson, Excitation, Fadel, Fepsp baseline, Gaba, Gabaergic, Glutamate, Haas, Hippocampus, Histamine, Histamine neurones, Histaminergic, Histaminergic neurons, Hypocretin, Hypocretin neurons, Hypocretins, Korotkova, Lecea, Locomotor activity, Memory functions, Narcolepsy, Narcoleptic dogs, Nervous system, Neuron, Neurones, Neurosci, Neuroscience, Nishino, Noradrenaline, Noradrenergic, Orexin, Orexin neurones, Orexin receptors, Orexin system, Orexinergic, Orexins, Parmentier, Pathway, Peptide, Physiol, Posterior hypothalamus, Proc natl acad, Receptor, Regul pept, Sakurai, Saper, Scandinavian, Selbach, Sergeeva, Serotonergic, Serotonin, Siegel, Siegel boehmer, Synaptic, Synaptic plasticity, Tuberomamillary, Tuberomamillary nucleus, Yanagisawa, Zeitzer.
Abstract
Orexin/hypocretin neurones in the posterior hypothalamus are mutually connected with noradrenergic, serotonergic, dopaminergic, histaminergic, and cholinergic neurone systems. They activate these targets by direct post‐synaptic and indirect pre‐synaptic mechanisms and in turn receive inhibitory feedback and excitatory feed forward control. With respect to behavioural state control, orexin/hypocretin neurones are conducting the orchestra of biogenic amines. This review highlights the role of these players in the control of energy administration, sleep–wake architecture, cortical activation, plasticity, and memory functions in health and disease.
Url:
DOI: 10.1111/j.1748-1716.2009.02015.x
Affiliations:
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They activate these targets by direct post‐synaptic and indirect pre‐synaptic mechanisms and in turn receive inhibitory feedback and excitatory feed forward control. With respect to behavioural state control, orexin/hypocretin neurones are conducting the orchestra of biogenic amines. This review highlights the role of these players in the control of energy administration, sleep–wake architecture, cortical activation, plasticity, and memory functions in health and disease.</div></front></TEI><affiliations><list><country><li>Allemagne</li></country><region><li>District de Düsseldorf</li><li>Rhénanie-du-Nord-Westphalie</li></region><settlement><li>Düsseldorf</li></settlement></list><tree><noCountry><name sortKey="Eriksson, K S" sort="Eriksson, K S" uniqKey="Eriksson K" first="K. S." last="Eriksson">K. S. Eriksson</name></noCountry><country name="Allemagne"><region name="Rhénanie-du-Nord-Westphalie"><name sortKey="Sergeeva, O A" sort="Sergeeva, O A" uniqKey="Sergeeva O" first="O. 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