Immune parameters in euthymic bipolar patients and normal volunteers
Identifieur interne : 000843 ( Istex/Curation ); précédent : 000842; suivant : 000844Immune parameters in euthymic bipolar patients and normal volunteers
Auteurs : Mark Hyman Rapaport [États-Unis]Source :
- Journal of Affective Disorders [ 0165-0327 ] ; 1994.
English descriptors
- Teeft :
- Affective, Affective disorders, Antithyroglobulin antibodies, Antithyroid antibodies, Antithyroid antibody prevalence, Assay, Autoantibody, Becton dickinson, Becton dickinson immunocytometry systems, Biol, Bipolar, Bipolar affective disorder, Bipolar disorder, Bipolar illness, Bipolar patients, Bipolar subjects, Clinical interview, Current protocols, Euthymic, Euthymic bipolar patients, Euthymic patients, Flow cytometry, Gender differences, Haggerty, Hematologic changes, Immune, Immune activation, Immune measures, Interassay variation, Intraassay variation, Irwin, Kronfol, Lithium, Lithium therapy, Lithium treatment, Lymphocyte, Lymphocyte culture, Lymphocyte population, Lymphocyte subsets, Major depression, Major depressive disorder, Mcallister, Monoclonal antibodies, Normal controls, Normal range, Normal volunteers, Panic disorder, Phenotypic, Phenotypic markers, Psychiatric patients, Psychiatry, Rapaport, Receptor, Room temperature, Sample size, Schizophrenic patients, Serum levels, Significant differences, Soluble receptor, Soluble receptors, Supernatant levels.
Abstract
Abstract: Immune system parameters were investigated in euthymic bipolar patients and matched normal volunteers. A review of the existing literature suggested that bipolar patients might be more likely to demonstrate signs of immune activation. Serum-soluble interleukin-2 receptors, circulating phenotypic lymphocyte markers, levels were measured. Euthymic bipolar patients and normal volunteers did not differ on any of these measures. Furthermore, bipolar patients could not be differentiated by medication status or gender. In conclusion, there was no evidence of immune system activation in euthymic bipolar patients.
Url:
DOI: 10.1016/0165-0327(94)90012-4
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<affiliation><mods:affiliation>∗ Address: Psychopharmacology Research Program, Department of Psychiatry, University of California at San Diego School of Medicine, 8950 Villa La Jolla Drive, Ste 2243, La Jolla, CA 92037, USA. Fax: (1) (619) 540-1491.</mods:affiliation>
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<term>Antithyroid antibody prevalence</term>
<term>Assay</term>
<term>Autoantibody</term>
<term>Becton dickinson</term>
<term>Becton dickinson immunocytometry systems</term>
<term>Biol</term>
<term>Bipolar</term>
<term>Bipolar affective disorder</term>
<term>Bipolar disorder</term>
<term>Bipolar illness</term>
<term>Bipolar patients</term>
<term>Bipolar subjects</term>
<term>Clinical interview</term>
<term>Current protocols</term>
<term>Euthymic</term>
<term>Euthymic bipolar patients</term>
<term>Euthymic patients</term>
<term>Flow cytometry</term>
<term>Gender differences</term>
<term>Haggerty</term>
<term>Hematologic changes</term>
<term>Immune</term>
<term>Immune activation</term>
<term>Immune measures</term>
<term>Interassay variation</term>
<term>Intraassay variation</term>
<term>Irwin</term>
<term>Kronfol</term>
<term>Lithium</term>
<term>Lithium therapy</term>
<term>Lithium treatment</term>
<term>Lymphocyte</term>
<term>Lymphocyte culture</term>
<term>Lymphocyte population</term>
<term>Lymphocyte subsets</term>
<term>Major depression</term>
<term>Major depressive disorder</term>
<term>Mcallister</term>
<term>Monoclonal antibodies</term>
<term>Normal controls</term>
<term>Normal range</term>
<term>Normal volunteers</term>
<term>Panic disorder</term>
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<term>Phenotypic markers</term>
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<term>Rapaport</term>
<term>Receptor</term>
<term>Room temperature</term>
<term>Sample size</term>
<term>Schizophrenic patients</term>
<term>Serum levels</term>
<term>Significant differences</term>
<term>Soluble receptor</term>
<term>Soluble receptors</term>
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<front><div type="abstract" xml:lang="en">Abstract: Immune system parameters were investigated in euthymic bipolar patients and matched normal volunteers. A review of the existing literature suggested that bipolar patients might be more likely to demonstrate signs of immune activation. Serum-soluble interleukin-2 receptors, circulating phenotypic lymphocyte markers, levels were measured. Euthymic bipolar patients and normal volunteers did not differ on any of these measures. Furthermore, bipolar patients could not be differentiated by medication status or gender. In conclusion, there was no evidence of immune system activation in euthymic bipolar patients.</div>
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