Concerted evolution of members of the multisequence family chAB4 located on various nonhomologous chromosomes
Identifieur interne : 000731 ( Istex/Corpus ); précédent : 000730; suivant : 000732Concerted evolution of members of the multisequence family chAB4 located on various nonhomologous chromosomes
Auteurs : Günter Assum ; Juanjo Pasantes ; Birgitta Gl Ser ; Werner Schempp ; Gudrun WöhrSource :
- Mammalian Genome [ 0938-8990 ] ; 1998-01-01.
Abstract
Abstract: During the last years it became obvious that a lot of families of long-range repetitive DNA elements are located within the genomes of mammals. The principles underlying the evolution of such families, therefore, may have a greater impact than anticipated on the evolution of the mammalian genome as a whole. One of these families, called chAB4, is represented with about 50 copies within the human and the chimpanzee genomes and with only a few copies in the genomes of gorilla, orang-utan, and gibbon. Members of chAB4 are located on 10 different human chromosomes. FISH of chAB4-specific probes to chromosome preparations of the great apes showed that chAB4 is located, with only one exception, at orthologous places in the human and the chimpanzee genome. About half the copies in the human genome belong to two species-specific subfamilies that evolved after the divergence of the human and the chimpanzee lineages. The analysis of chAB4-specific PCR-products derived from DNA of rodent/human cell hybrids showed that members of the two human-specific subfamilies can be found on 9 of the 10 chAB4-carrying chromosomes. Taken together, these results demonstrate that the members of DNA sequence families can evolve as a unit despite their location at multiple sites on different chromosomes. The concerted evolution of the family members is a result of frequent exchanges of DNA sequences between copies located on different chromosomes. Interchromosomal exchanges apparently take place without greater alterations in chromosome structure.
Url:
DOI: 10.1007/s003359900680
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ISTEX:894A0A12AB8DFAD3D277F1B7B5A2F3CE125FD789Le document en format XML
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The principles underlying the evolution of such families, therefore, may have a greater impact than anticipated on the evolution of the mammalian genome as a whole. One of these families, called chAB4, is represented with about 50 copies within the human and the chimpanzee genomes and with only a few copies in the genomes of gorilla, orang-utan, and gibbon. Members of chAB4 are located on 10 different human chromosomes. FISH of chAB4-specific probes to chromosome preparations of the great apes showed that chAB4 is located, with only one exception, at orthologous places in the human and the chimpanzee genome. About half the copies in the human genome belong to two species-specific subfamilies that evolved after the divergence of the human and the chimpanzee lineages. The analysis of chAB4-specific PCR-products derived from DNA of rodent/human cell hybrids showed that members of the two human-specific subfamilies can be found on 9 of the 10 chAB4-carrying chromosomes. Taken together, these results demonstrate that the members of DNA sequence families can evolve as a unit despite their location at multiple sites on different chromosomes. The concerted evolution of the family members is a result of frequent exchanges of DNA sequences between copies located on different chromosomes. Interchromosomal exchanges apparently take place without greater alterations in chromosome structure.</div></front></TEI><istex><corpusName>springer-journals</corpusName><author><json:item><name>Günter Assum</name><affiliations><json:string>Abteilung Humangenetik der Universität Ulm, Albert-Einstein-Allee 11, D-89081, Ulm, Germany</json:string></affiliations></json:item><json:item><name>Juanjo Pasantes</name><affiliations><json:string>Institut für Humangenetik und Anthropologie der Albert-Ludwigs-Universität, D-79106, Freiburg, Germany</json:string><json:string>Genetics Laboratory of the University Vigo, Spain</json:string></affiliations></json:item><json:item><name>Birgitta Gläser</name><affiliations><json:string>Institut für Humangenetik und Anthropologie der Albert-Ludwigs-Universität, D-79106, Freiburg, Germany</json:string></affiliations></json:item><json:item><name>Werner Schempp</name><affiliations><json:string>Institut für Humangenetik und Anthropologie der Albert-Ludwigs-Universität, D-79106, Freiburg, Germany</json:string></affiliations></json:item><json:item><name>Gudrun Wöhr</name><affiliations><json:string>Abteilung Humangenetik der Universität Ulm, Albert-Einstein-Allee 11, D-89081, Ulm, Germany</json:string></affiliations></json:item></author><articleId><json:string>90100058</json:string><json:string>Art12</json:string></articleId><arkIstex>ark:/67375/VQC-BMP9SKCD-V</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>OriginalPaper</json:string></originalGenre><abstract>Abstract: During the last years it became obvious that a lot of families of long-range repetitive DNA elements are located within the genomes of mammals. 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Genome</title><title level="j" type="sub">Incorporating Mouse Genome</title><title level="j" type="abbrev">Mammalian Genome</title><idno type="pISSN">0938-8990</idno><idno type="eISSN">1432-1777</idno><idno type="journal-ID">true</idno><idno type="issue-article-count">29</idno><idno type="volume-issue-count">12</idno><imprint><publisher>Springer-Verlag</publisher><pubPlace>New York</pubPlace><date type="published" when="1998-01-01"></date><biblScope unit="volume">9</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="58">58</biblScope><biblScope unit="page" to="63">63</biblScope></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>1997-03-20</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Abstract: During the last years it became obvious that a lot of families of long-range repetitive DNA elements are located within the genomes of mammals. The principles underlying the evolution of such families, therefore, may have a greater impact than anticipated on the evolution of the mammalian genome as a whole. One of these families, called chAB4, is represented with about 50 copies within the human and the chimpanzee genomes and with only a few copies in the genomes of gorilla, orang-utan, and gibbon. Members of chAB4 are located on 10 different human chromosomes. FISH of chAB4-specific probes to chromosome preparations of the great apes showed that chAB4 is located, with only one exception, at orthologous places in the human and the chimpanzee genome. About half the copies in the human genome belong to two species-specific subfamilies that evolved after the divergence of the human and the chimpanzee lineages. The analysis of chAB4-specific PCR-products derived from DNA of rodent/human cell hybrids showed that members of the two human-specific subfamilies can be found on 9 of the 10 chAB4-carrying chromosomes. Taken together, these results demonstrate that the members of DNA sequence families can evolve as a unit despite their location at multiple sites on different chromosomes. The concerted evolution of the family members is a result of frequent exchanges of DNA sequences between copies located on different chromosomes. Interchromosomal exchanges apparently take place without greater alterations in chromosome structure.</p></abstract><textClass><keywords scheme="Journal-Subject-Group"><list><label>L</label><label>L16008</label><label>H12005</label><label>L25007</label><item><term>Life Sciences</term></item><item><term>Cell Biology</term></item><item><term>Anatomy</term></item><item><term>Zoology</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="1997-03-20">Created</change><change when="1998-01-01">Published</change><change xml:id="refBibs-istex" who="#ISTEX-API" when="2017-12-1">References added</change></revisionDesc></teiHeader></istex:fulltextTEI></fulltext><metadata><istex:metadataXml wicri:clean="corpus springer-journals not found" wicri:toSee="no header"><istex:xmlDeclaration>version="1.0" encoding="UTF-8"</istex:xmlDeclaration><istex:docType PUBLIC="-//Springer-Verlag//DTD A++ V2.4//EN" URI="http://devel.springer.de/A++/V2.4/DTD/A++V2.4.dtd" 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Grant="Restricted"></ESMGrant></ArticleGrants><ArticleContext><JournalID>335</JournalID><VolumeIDStart>9</VolumeIDStart><VolumeIDEnd>9</VolumeIDEnd><IssueIDStart>1</IssueIDStart><IssueIDEnd>1</IssueIDEnd></ArticleContext></ArticleInfo><ArticleHeader><AuthorGroup><Author AffiliationIDS="Aff1" CorrespondingAffiliationID="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Günter</GivenName><FamilyName>Assum</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff2 Aff3"><AuthorName DisplayOrder="Western"><GivenName>Juanjo</GivenName><FamilyName>Pasantes</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff2"><AuthorName DisplayOrder="Western"><GivenName>Birgitta</GivenName><FamilyName>Gläser</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff2"><AuthorName DisplayOrder="Western"><GivenName>Werner</GivenName><FamilyName>Schempp</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Gudrun</GivenName><FamilyName>Wöhr</FamilyName></AuthorName></Author><Affiliation ID="Aff1"><OrgName>Abteilung Humangenetik der Universität Ulm</OrgName><OrgAddress><Street>Albert-Einstein-Allee 11</Street><Postcode>D-89081</Postcode><City>Ulm</City><Country>Germany</Country></OrgAddress></Affiliation><Affiliation ID="Aff2"><OrgName>Institut für Humangenetik und Anthropologie der Albert-Ludwigs-Universität</OrgName><OrgAddress><Postcode>D-79106</Postcode><City>Freiburg</City><Country>Germany</Country></OrgAddress></Affiliation><Affiliation ID="Aff3"><OrgName>Genetics Laboratory of the University Vigo</OrgName><OrgAddress><Country>Spain</Country></OrgAddress></Affiliation></AuthorGroup><Abstract ID="Abs1" Language="En"><Heading>Abstract</Heading><Para TextBreak="No">During the last years it became obvious that a lot of families of long-range repetitive DNA elements are located within the genomes of mammals. The principles underlying the evolution of such families, therefore, may have a greater impact than anticipated on the evolution of the mammalian genome as a whole. One of these families, called chAB4, is represented with about 50 copies within the human and the chimpanzee genomes and with only a few copies in the genomes of gorilla, orang-utan, and gibbon. Members of chAB4 are located on 10 different human chromosomes. FISH of chAB4-specific probes to chromosome preparations of the great apes showed that chAB4 is located, with only one exception, at orthologous places in the human and the chimpanzee genome. About half the copies in the human genome belong to two species-specific subfamilies that evolved after the divergence of the human and the chimpanzee lineages. The analysis of chAB4-specific PCR-products derived from DNA of rodent/human cell hybrids showed that members of the two human-specific subfamilies can be found on 9 of the 10 chAB4-carrying chromosomes. Taken together, these results demonstrate that the members of DNA sequence families can evolve as a unit despite their location at multiple sites on different chromosomes. The concerted evolution of the family members is a result of frequent exchanges of DNA sequences between copies located on different chromosomes. Interchromosomal exchanges apparently take place without greater alterations in chromosome structure.</Para></Abstract></ArticleHeader><NoBody></NoBody></Article></Issue></Volume></Journal></Publisher></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Concerted evolution of members of the multisequence family chAB4 located on various nonhomologous chromosomes</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Concerted evolution of members of the multisequence family chAB4 located on various nonhomologous chromosomes</title></titleInfo><name type="personal" displayLabel="corresp"><namePart type="given">Günter</namePart><namePart type="family">Assum</namePart><affiliation>Abteilung Humangenetik der Universität Ulm, Albert-Einstein-Allee 11, D-89081, Ulm, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Juanjo</namePart><namePart type="family">Pasantes</namePart><affiliation>Institut für Humangenetik und Anthropologie der Albert-Ludwigs-Universität, D-79106, Freiburg, Germany</affiliation><affiliation>Genetics Laboratory of the University Vigo, Spain</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Birgitta</namePart><namePart type="family">Gläser</namePart><affiliation>Institut für Humangenetik und Anthropologie der Albert-Ludwigs-Universität, D-79106, Freiburg, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Werner</namePart><namePart type="family">Schempp</namePart><affiliation>Institut für Humangenetik und Anthropologie der Albert-Ludwigs-Universität, D-79106, Freiburg, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Gudrun</namePart><namePart type="family">Wöhr</namePart><affiliation>Abteilung Humangenetik der Universität Ulm, Albert-Einstein-Allee 11, D-89081, Ulm, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="OriginalPaper" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-1JC4F85T-7">research-article</genre><originInfo><publisher>Springer-Verlag</publisher><place><placeTerm type="text">New York</placeTerm></place><dateCreated encoding="w3cdtf">1997-03-20</dateCreated><dateIssued encoding="w3cdtf">1998-01-01</dateIssued><dateIssued encoding="w3cdtf">1998</dateIssued><copyrightDate encoding="w3cdtf">1998</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><abstract lang="en">Abstract: During the last years it became obvious that a lot of families of long-range repetitive DNA elements are located within the genomes of mammals. The principles underlying the evolution of such families, therefore, may have a greater impact than anticipated on the evolution of the mammalian genome as a whole. One of these families, called chAB4, is represented with about 50 copies within the human and the chimpanzee genomes and with only a few copies in the genomes of gorilla, orang-utan, and gibbon. Members of chAB4 are located on 10 different human chromosomes. FISH of chAB4-specific probes to chromosome preparations of the great apes showed that chAB4 is located, with only one exception, at orthologous places in the human and the chimpanzee genome. About half the copies in the human genome belong to two species-specific subfamilies that evolved after the divergence of the human and the chimpanzee lineages. The analysis of chAB4-specific PCR-products derived from DNA of rodent/human cell hybrids showed that members of the two human-specific subfamilies can be found on 9 of the 10 chAB4-carrying chromosomes. Taken together, these results demonstrate that the members of DNA sequence families can evolve as a unit despite their location at multiple sites on different chromosomes. The concerted evolution of the family members is a result of frequent exchanges of DNA sequences between copies located on different chromosomes. Interchromosomal exchanges apparently take place without greater alterations in chromosome structure.</abstract><note>Original Contributions</note><relatedItem type="host"><titleInfo><title>Mammalian Genome</title><subTitle>Incorporating Mouse Genome</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mammalian Genome</title></titleInfo><genre type="journal" displayLabel="Archive Journal" authority="ISTEX" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><originInfo><publisher>Springer</publisher><dateIssued encoding="w3cdtf">1998-01-01</dateIssued><copyrightDate encoding="w3cdtf">1998</copyrightDate></originInfo><subject><genre>Journal-Subject-Group</genre><topic authority="SpringerSubjectCodes" authorityURI="L">Life Sciences</topic><topic authority="SpringerSubjectCodes" authorityURI="L16008">Cell Biology</topic><topic authority="SpringerSubjectCodes" authorityURI="H12005">Anatomy</topic><topic authority="SpringerSubjectCodes" authorityURI="L25007">Zoology</topic></subject><identifier type="ISSN">0938-8990</identifier><identifier type="eISSN">1432-1777</identifier><identifier type="JournalID">335</identifier><identifier type="IssueArticleCount">29</identifier><identifier type="VolumeIssueCount">12</identifier><part><date>1998</date><detail type="volume"><number>9</number><caption>vol.</caption></detail><detail type="issue"><number>1</number><caption>no.</caption></detail><extent unit="pages"><start>58</start><end>63</end></extent></part><recordInfo><recordOrigin>Springer-Verlag, 1998</recordOrigin></recordInfo></relatedItem><identifier type="istex">894A0A12AB8DFAD3D277F1B7B5A2F3CE125FD789</identifier><identifier type="ark">ark:/67375/VQC-BMP9SKCD-V</identifier><identifier type="DOI">10.1007/s003359900680</identifier><identifier type="ArticleID">90100058</identifier><identifier type="ArticleID">Art12</identifier><accessCondition type="use and reproduction" contentType="copyright">Springer-Verlag New York Inc, 1998</accessCondition><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-3XSW68JL-F">springer</recordContentSource><recordOrigin>Springer-Verlag New York Inc, 1998</recordOrigin></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/document/894A0A12AB8DFAD3D277F1B7B5A2F3CE125FD789/metadata/json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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