The aging of Wolff's “law”: Ontogeny and responses to mechanical loading in cortical bone
Identifieur interne : 001B95 ( Main/Corpus ); précédent : 001B94; suivant : 001B96The aging of Wolff's “law”: Ontogeny and responses to mechanical loading in cortical bone
Auteurs : Osbjorn M. Pearson ; Daniel E. LiebermanSource :
- American Journal of Physical Anthropology [ 0002-9483 ] ; 2004.
English descriptors
- KwdEn :
Abstract
The premise that bones grow and remodel throughout life to adapt to their mechanical enironment is often called Wolff's law. Wolff's law, however, is not always true, and in fact comprises a variety of different processes that are best considered separately. Here we review the molecular and physiological mechanisms by which bone senses, transduces, and responds to mechanical loads, and the effects of aging processes on the relationship (if any) between cortical bone form and mechanical function. Experimental and comparative evidence suggests that cortical bone is primarily responsive to strain prior to sexual maturity, both in terms of the rate of new bone growth (modeling) as well as rates of turnover (Haversian remodeling). Rates of modeling and Haversian remodeling, however, vary greatly at different skeletal sites. In addition, there is no simple relationship between the orientation of loads in long bone diaphyses and their cross‐sectional geometry. In combination, these data caution against assuming without testing adaptationist views about form‐function relationships in order to infer adult activity patterns from skeletal features such as cross‐sectional geometry, cortical bones density, and musculo‐skeletal stress markers. Efforts to infer function from shape in the human skeleton should be based on biomechanical and developmental models that are experimentally tested and validated. Yrbk Phys Anthropol 47:63–99, 2004. © 2004 Wiley‐Liss, Inc.
Url:
DOI: 10.1002/ajpa.20155
Links to Exploration step
ISTEX:DF63C33B15D43B78C0E2B91B066F2115BAE37613Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">The aging of Wolff's “law”: Ontogeny and responses to mechanical loading in cortical bone</title><author><name sortKey="Pearson, Osbjorn M" sort="Pearson, Osbjorn M" uniqKey="Pearson O" first="Osbjorn M." last="Pearson">Osbjorn M. Pearson</name><affiliation><mods:affiliation>Department of Anthropology, University of New Mexico, Albuquerque, New Mexico 87198‐1086</mods:affiliation></affiliation></author><author><name sortKey="Lieberman, Daniel E" sort="Lieberman, Daniel E" uniqKey="Lieberman D" first="Daniel E." last="Lieberman">Daniel E. Lieberman</name><affiliation><mods:affiliation>Peabody Museum, Harvard University, Cambridge, Massachusetts 02138</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:DF63C33B15D43B78C0E2B91B066F2115BAE37613</idno><date when="2004" year="2004">2004</date><idno type="doi">10.1002/ajpa.20155</idno><idno type="url">https://api.istex.fr/document/DF63C33B15D43B78C0E2B91B066F2115BAE37613/fulltext/pdf</idno><idno type="wicri:Area/Main/Corpus">001B95</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">The aging of Wolff's “law”: Ontogeny and responses to mechanical loading in cortical bone</title><author><name sortKey="Pearson, Osbjorn M" sort="Pearson, Osbjorn M" uniqKey="Pearson O" first="Osbjorn M." last="Pearson">Osbjorn M. Pearson</name><affiliation><mods:affiliation>Department of Anthropology, University of New Mexico, Albuquerque, New Mexico 87198‐1086</mods:affiliation></affiliation></author><author><name sortKey="Lieberman, Daniel E" sort="Lieberman, Daniel E" uniqKey="Lieberman D" first="Daniel E." last="Lieberman">Daniel E. Lieberman</name><affiliation><mods:affiliation>Peabody Museum, Harvard University, Cambridge, Massachusetts 02138</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">American Journal of Physical Anthropology</title><title level="j" type="abbrev">Am. J. Phys. Anthropol.</title><idno type="ISSN">0002-9483</idno><idno type="eISSN">1096-8644</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2004">2004</date><biblScope unit="volume">125</biblScope><biblScope unit="issue">S39</biblScope><biblScope unit="supplement">39</biblScope><biblScope unit="page" from="63">63</biblScope><biblScope unit="page" to="99">99</biblScope></imprint><idno type="ISSN">0002-9483</idno></series><idno type="istex">DF63C33B15D43B78C0E2B91B066F2115BAE37613</idno><idno type="DOI">10.1002/ajpa.20155</idno><idno type="ArticleID">AJPA20155</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0002-9483</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Haversian remodeling</term><term>modeling</term><term>ontogeny</term><term>senesence</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The premise that bones grow and remodel throughout life to adapt to their mechanical enironment is often called Wolff's law. Wolff's law, however, is not always true, and in fact comprises a variety of different processes that are best considered separately. Here we review the molecular and physiological mechanisms by which bone senses, transduces, and responds to mechanical loads, and the effects of aging processes on the relationship (if any) between cortical bone form and mechanical function. Experimental and comparative evidence suggests that cortical bone is primarily responsive to strain prior to sexual maturity, both in terms of the rate of new bone growth (modeling) as well as rates of turnover (Haversian remodeling). Rates of modeling and Haversian remodeling, however, vary greatly at different skeletal sites. In addition, there is no simple relationship between the orientation of loads in long bone diaphyses and their cross‐sectional geometry. In combination, these data caution against assuming without testing adaptationist views about form‐function relationships in order to infer adult activity patterns from skeletal features such as cross‐sectional geometry, cortical bones density, and musculo‐skeletal stress markers. Efforts to infer function from shape in the human skeleton should be based on biomechanical and developmental models that are experimentally tested and validated. Yrbk Phys Anthropol 47:63–99, 2004. © 2004 Wiley‐Liss, Inc.</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Osbjorn M. Pearson</name><affiliations><json:string>Department of Anthropology, University of New Mexico, Albuquerque, New Mexico 87198‐1086</json:string></affiliations></json:item><json:item><name>Daniel E. Lieberman</name><affiliations><json:string>Peabody Museum, Harvard University, Cambridge, Massachusetts 02138</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>ontogeny</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>senesence</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Haversian remodeling</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>modeling</value></json:item></subject><language><json:string>eng</json:string></language><abstract>The premise that bones grow and remodel throughout life to adapt to their mechanical enironment is often called Wolff's law. Wolff's law, however, is not always true, and in fact comprises a variety of different processes that are best considered separately. Here we review the molecular and physiological mechanisms by which bone senses, transduces, and responds to mechanical loads, and the effects of aging processes on the relationship (if any) between cortical bone form and mechanical function. Experimental and comparative evidence suggests that cortical bone is primarily responsive to strain prior to sexual maturity, both in terms of the rate of new bone growth (modeling) as well as rates of turnover (Haversian remodeling). Rates of modeling and Haversian remodeling, however, vary greatly at different skeletal sites. In addition, there is no simple relationship between the orientation of loads in long bone diaphyses and their cross‐sectional geometry. In combination, these data caution against assuming without testing adaptationist views about form‐function relationships in order to infer adult activity patterns from skeletal features such as cross‐sectional geometry, cortical bones density, and musculo‐skeletal stress markers. Efforts to infer function from shape in the human skeleton should be based on biomechanical and developmental models that are experimentally tested and validated. Yrbk Phys Anthropol 47:63–99, 2004. © 2004 Wiley‐Liss, Inc.</abstract><qualityIndicators><score>7.568</score><pdfVersion>1.3</pdfVersion><pdfPageSize>594 x 792 pts</pdfPageSize><refBibsNative>true</refBibsNative><keywordCount>4</keywordCount><abstractCharCount>1472</abstractCharCount><pdfWordCount>28832</pdfWordCount><pdfCharCount>177484</pdfCharCount><pdfPageCount>37</pdfPageCount><abstractWordCount>214</abstractWordCount></qualityIndicators><title>The aging of Wolff's “law”: Ontogeny and responses to mechanical loading in cortical bone</title><genre><json:string>article</json:string></genre><host><volume>125</volume><pages><total>37</total><last>99</last><first>63</first></pages><issn><json:string>0002-9483</json:string></issn><issue>S39</issue><subject><json:item><value>Article</value></json:item></subject><genre></genre><language><json:string>unknown</json:string></language><eissn><json:string>1096-8644</json:string></eissn><title>American Journal of Physical Anthropology</title><doi><json:string>10.1002/(ISSN)1096-8644</json:string></doi></host><publicationDate>2004</publicationDate><copyrightDate>2004</copyrightDate><doi><json:string>10.1002/ajpa.20155</json:string></doi><id>DF63C33B15D43B78C0E2B91B066F2115BAE37613</id><fulltext><json:item><original>true</original><mimetype>application/pdf</mimetype><extension>pdf</extension><uri>https://api.istex.fr/document/DF63C33B15D43B78C0E2B91B066F2115BAE37613/fulltext/pdf</uri></json:item><json:item><original>false</original><mimetype>application/zip</mimetype><extension>zip</extension><uri>https://api.istex.fr/document/DF63C33B15D43B78C0E2B91B066F2115BAE37613/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/DF63C33B15D43B78C0E2B91B066F2115BAE37613/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">The aging of Wolff's “law”: Ontogeny and responses to mechanical loading in cortical bone</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><availability><p>WILEY</p></availability><date>2004</date></publicationStmt><notesStmt><note>NSF - No. IBN 96‐03833;</note><note>American Federation for Aging Research</note><note>George Washington University</note><note>Harvard University</note><note>University of New Mexico</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">The aging of Wolff's “law”: Ontogeny and responses to mechanical loading in cortical bone</title><author><persName><forename type="first">Osbjorn M.</forename><surname>Pearson</surname></persName><note type="correspondence"><p>Correspondence: Department of Anthropology, University of New Mexico, MSC01 1040, Albuquerque, NM 87198‐1086</p></note><affiliation>Department of Anthropology, University of New Mexico, Albuquerque, New Mexico 87198‐1086</affiliation></author><author><persName><forename type="first">Daniel E.</forename><surname>Lieberman</surname></persName><affiliation>Peabody Museum, Harvard University, Cambridge, Massachusetts 02138</affiliation></author></analytic><monogr><title level="j">American Journal of Physical Anthropology</title><title level="j" type="abbrev">Am. J. Phys. Anthropol.</title><idno type="pISSN">0002-9483</idno><idno type="eISSN">1096-8644</idno><idno type="DOI">10.1002/(ISSN)1096-8644</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2004"></date><biblScope unit="volume">125</biblScope><biblScope unit="issue">S39</biblScope><biblScope unit="supplement">39</biblScope><biblScope unit="page" from="63">63</biblScope><biblScope unit="page" to="99">99</biblScope></imprint></monogr><idno type="istex">DF63C33B15D43B78C0E2B91B066F2115BAE37613</idno><idno type="DOI">10.1002/ajpa.20155</idno><idno type="ArticleID">AJPA20155</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2004</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>The premise that bones grow and remodel throughout life to adapt to their mechanical enironment is often called Wolff's law. Wolff's law, however, is not always true, and in fact comprises a variety of different processes that are best considered separately. Here we review the molecular and physiological mechanisms by which bone senses, transduces, and responds to mechanical loads, and the effects of aging processes on the relationship (if any) between cortical bone form and mechanical function. Experimental and comparative evidence suggests that cortical bone is primarily responsive to strain prior to sexual maturity, both in terms of the rate of new bone growth (modeling) as well as rates of turnover (Haversian remodeling). Rates of modeling and Haversian remodeling, however, vary greatly at different skeletal sites. In addition, there is no simple relationship between the orientation of loads in long bone diaphyses and their cross‐sectional geometry. In combination, these data caution against assuming without testing adaptationist views about form‐function relationships in order to infer adult activity patterns from skeletal features such as cross‐sectional geometry, cortical bones density, and musculo‐skeletal stress markers. Efforts to infer function from shape in the human skeleton should be based on biomechanical and developmental models that are experimentally tested and validated. Yrbk Phys Anthropol 47:63–99, 2004. © 2004 Wiley‐Liss, Inc.</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>ontogeny</term></item><item><term>senesence</term></item><item><term>Haversian remodeling</term></item><item><term>modeling</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>article category</head><item><term>Article</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2004">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/DF63C33B15D43B78C0E2B91B066F2115BAE37613/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>Hoboken</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1096-8644</doi><issn type="print">0002-9483</issn><issn type="electronic">1096-8644</issn><idGroup><id type="product" value="AJPA"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY">American Journal of Physical Anthropology</title><title type="short">Am. J. Phys. Anthropol.</title></titleGroup></publicationMeta><publicationMeta level="part" position="50"><doi origin="wiley" registered="yes">10.1002/ajpa.v125:39+</doi><titleGroup><title type="supplementTitle">Yearbook of Physical Anthropology</title><title type="supplementSeriesTitle">YearBook Series 47</title></titleGroup><numberingGroup><numbering type="journalVolume" number="125">125</numbering><numbering type="journalIssue">S39</numbering><numbering type="supplement" number="39">39</numbering><numbering type="supplementSeriesVolume">125</numbering></numberingGroup><coverDate startDate="2004">2004</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="4" status="forIssue"><doi origin="wiley" registered="yes">10.1002/ajpa.20155</doi><idGroup><id type="unit" value="AJPA20155"></id></idGroup><countGroup><count type="pageTotal" number="37"></count></countGroup><titleGroup><title type="articleCategory">Article</title><title type="tocHeading1">Articles</title></titleGroup><copyright ownership="publisher">Copyright © 2004 Wiley‐Liss, Inc.</copyright><eventGroup><event type="firstOnline" date="2004-12-16"></event><event type="publishedOnlineFinalForm" date="2004-12-16"></event><event type="xmlConverted" agent="Converter:JWSART34_TO_WML3G version:2.3.18.1 mode:FullText source:HeaderRef result:HeaderRef" date="2010-09-09"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-01-02"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-14"></event></eventGroup><numberingGroup><numbering type="pageFirst">63</numbering><numbering type="pageLast">99</numbering></numberingGroup><correspondenceTo>Department of Anthropology, University of New Mexico, MSC01 1040, Albuquerque, NM 87198‐1086</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:AJPA.AJPA20155.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="12"></count><count type="tableTotal" number="4"></count><count type="referenceTotal" number="432"></count><count type="wordTotal" number="32138"></count></countGroup><titleGroup><title type="main" xml:lang="en">The aging of Wolff's “law”: Ontogeny and responses to mechanical loading in cortical bone</title><title type="short" xml:lang="en">Ontogeny and Responses to Loading</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1" corresponding="yes"><personName><givenNames>Osbjorn M.</givenNames><familyName>Pearson</familyName></personName><contactDetails><email>ompear@unm.edu</email></contactDetails></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af2"><personName><givenNames>Daniel E.</givenNames><familyName>Lieberman</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="US" type="organization"><unparsedAffiliation>Department of Anthropology, University of New Mexico, Albuquerque, New Mexico 87198‐1086</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="US" type="organization"><unparsedAffiliation>Peabody Museum, Harvard University, Cambridge, Massachusetts 02138</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">ontogeny</keyword><keyword xml:id="kwd2">senesence</keyword><keyword xml:id="kwd3">Haversian remodeling</keyword><keyword xml:id="kwd4">modeling</keyword></keywordGroup><fundingInfo><fundingAgency>NSF</fundingAgency><fundingNumber>IBN 96‐03833</fundingNumber></fundingInfo><fundingInfo><fundingAgency>American Federation for Aging Research</fundingAgency></fundingInfo><fundingInfo><fundingAgency>George Washington University</fundingAgency></fundingInfo><fundingInfo><fundingAgency>Harvard University</fundingAgency></fundingInfo><fundingInfo><fundingAgency>University of New Mexico</fundingAgency></fundingInfo><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>The premise that bones grow and remodel throughout life to adapt to their mechanical enironment is often called Wolff's law. Wolff's law, however, is not always true, and in fact comprises a variety of different processes that are best considered separately. Here we review the molecular and physiological mechanisms by which bone senses, transduces, and responds to mechanical loads, and the effects of aging processes on the relationship (if any) between cortical bone form and mechanical function. Experimental and comparative evidence suggests that cortical bone is primarily responsive to strain prior to sexual maturity, both in terms of the rate of new bone growth (modeling) as well as rates of turnover (Haversian remodeling). Rates of modeling and Haversian remodeling, however, vary greatly at different skeletal sites. In addition, there is no simple relationship between the orientation of loads in long bone diaphyses and their cross‐sectional geometry. In combination, these data caution against assuming without testing adaptationist views about form‐function relationships in order to infer adult activity patterns from skeletal features such as cross‐sectional geometry, cortical bones density, and musculo‐skeletal stress markers. Efforts to infer function from shape in the human skeleton should be based on biomechanical and developmental models that are experimentally tested and validated. Yrbk Phys Anthropol 47:63–99, 2004. © 2004 Wiley‐Liss, Inc.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>The aging of Wolff's “law”: Ontogeny and responses to mechanical loading in cortical bone</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Ontogeny and Responses to Loading</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>The aging of Wolff's “law”: Ontogeny and responses to mechanical loading in cortical bone</title></titleInfo><name type="personal"><namePart type="given">Osbjorn M.</namePart><namePart type="family">Pearson</namePart><affiliation>Department of Anthropology, University of New Mexico, Albuquerque, New Mexico 87198‐1086</affiliation><description>Correspondence: Department of Anthropology, University of New Mexico, MSC01 1040, Albuquerque, NM 87198‐1086</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Daniel E.</namePart><namePart type="family">Lieberman</namePart><affiliation>Peabody Museum, Harvard University, Cambridge, Massachusetts 02138</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2004</dateIssued><copyrightDate encoding="w3cdtf">2004</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">12</extent><extent unit="tables">4</extent><extent unit="references">432</extent><extent unit="words">32138</extent></physicalDescription><abstract lang="en">The premise that bones grow and remodel throughout life to adapt to their mechanical enironment is often called Wolff's law. Wolff's law, however, is not always true, and in fact comprises a variety of different processes that are best considered separately. Here we review the molecular and physiological mechanisms by which bone senses, transduces, and responds to mechanical loads, and the effects of aging processes on the relationship (if any) between cortical bone form and mechanical function. Experimental and comparative evidence suggests that cortical bone is primarily responsive to strain prior to sexual maturity, both in terms of the rate of new bone growth (modeling) as well as rates of turnover (Haversian remodeling). Rates of modeling and Haversian remodeling, however, vary greatly at different skeletal sites. In addition, there is no simple relationship between the orientation of loads in long bone diaphyses and their cross‐sectional geometry. In combination, these data caution against assuming without testing adaptationist views about form‐function relationships in order to infer adult activity patterns from skeletal features such as cross‐sectional geometry, cortical bones density, and musculo‐skeletal stress markers. Efforts to infer function from shape in the human skeleton should be based on biomechanical and developmental models that are experimentally tested and validated. Yrbk Phys Anthropol 47:63–99, 2004. © 2004 Wiley‐Liss, Inc.</abstract><note type="funding">NSF - No. IBN 96‐03833; </note><note type="funding">American Federation for Aging Research</note><note type="funding">George Washington University</note><note type="funding">Harvard University</note><note type="funding">University of New Mexico</note><subject lang="en"><genre>Keywords</genre><topic>ontogeny</topic><topic>senesence</topic><topic>Haversian remodeling</topic><topic>modeling</topic></subject><relatedItem type="host"><titleInfo><title>American Journal of Physical Anthropology</title></titleInfo><titleInfo type="abbreviated"><title>Am. J. Phys. Anthropol.</title></titleInfo><genre type="Journal">journal</genre><subject><genre>article category</genre><topic>Article</topic></subject><identifier type="ISSN">0002-9483</identifier><identifier type="eISSN">1096-8644</identifier><identifier type="DOI">10.1002/(ISSN)1096-8644</identifier><identifier type="PublisherID">AJPA</identifier><part><date>2004</date><detail type="volume"><caption>vol.</caption><number>125</number></detail><detail type="issue"><caption>no.</caption><number>S39</number></detail><detail type="supplement"><caption>Suppl. no.</caption><number>39</number></detail><extent unit="pages"><start>63</start><end>99</end><total>37</total></extent></part></relatedItem><identifier type="istex">DF63C33B15D43B78C0E2B91B066F2115BAE37613</identifier><identifier type="DOI">10.1002/ajpa.20155</identifier><identifier type="ArticleID">AJPA20155</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2004 Wiley‐Liss, Inc.</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Musique/explor/SchutzV1/Data/Main/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001B95 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Corpus/biblio.hfd -nk 001B95 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Musique
|area= SchutzV1
|flux= Main
|étape= Corpus
|type= RBID
|clé= ISTEX:DF63C33B15D43B78C0E2B91B066F2115BAE37613
|texte= The aging of Wolff's “law”: Ontogeny and responses to mechanical loading in cortical bone
}}
| This area was generated with Dilib version V0.6.38. |  |