Serveur d'exploration sur Heinrich Schütz

Attention, ce site est en cours de développement !
Attention, site généré par des moyens informatiques à partir de corpus bruts.
Les informations ne sont donc pas validées.

Cancer mortality in a cohort of male German iron foundry workers

Identifieur interne : 000D67 ( Main/Corpus ); précédent : 000D66; suivant : 000D68

Cancer mortality in a cohort of male German iron foundry workers

Auteurs : Karl Einrich Adzersen ; Nikolaus Becker ; Karen Steindorf ; Rainer Frentzel Eyme

Source :

RBID : ISTEX:266DD4AE60847656A4B8D1A09E44A3AF1EC871FA

English descriptors

Abstract

Background: Observations of an increased incidence of cancers of the upper aero‐digestive tract (pharynx, esophagus, larynx, lung) among workers of local German foundries gave rise to concern about a potentially elevated occupational risk of those cancer sites. The purpose of the study was to examine whether occupational exposure in iron foundries increases the risk of cancer. Methods: A historical cohort study of 17,708 male German production workers in 37 iron foundries who were first employed in 1950–1985 with a minimum employment period of 1 year was initiated. Employment and occupational histories were collected. Mortality was compared with that of the German general population during 1950–1993 using a new method for computing the SMR when not all causes of death are available (called SMR*). Results: Mortality from all causes was elevated to SMR = 115.4 (95% confidence interval (CI) = 111.9–119.1), as was for total cancer (SMR* = 123.8, CI = 102.1–152.6), especially cancers of the lung (SMR* = 163.9, CI = 123.9–223.0) and liver (SMR* = 322.5, CI = 149.5–844.8), and diseases of the respiratory system (SMR* = 147.6, CI = 100.4–221.5). Non‐significant elevations of mortality were also found for cancers of the mouth and pharynx (SMR* = 153.5, CI = 82.3–359.8) and larynx (SMR* = 173.1, CI = 85.5–550.5). Mortality from various causes of death was higher among workers with shorter exposure periods than among long‐term employees. The elevated mortality persisted for years and decades after termination of employment. Conclusions: The results provide further evidence for an increased risk of lung cancer and possibly other cancers of the upper aero‐digestive tract among foundry workers. Special attention should be paid to the strongly increased mortality from liver cancer and the mortality pattern among employees having terminated work. Am. J. Ind. Med. 43:295–305, 2003. © 2003 Wiley‐Liss, Inc.

Url:
DOI: 10.1002/ajim.10187

Links to Exploration step

ISTEX:266DD4AE60847656A4B8D1A09E44A3AF1EC871FA

Le document en format XML

<record>
<TEI wicri:istexFullTextTei="biblStruct">
<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="en">Cancer mortality in a cohort of male German iron foundry workers</title>
<author>
<name sortKey="Adzersen, Karl Einrich" sort="Adzersen, Karl Einrich" uniqKey="Adzersen K" first="Karl Einrich" last="Adzersen">Karl Einrich Adzersen</name>
<affiliation>
<mods:affiliation>German Cancer Research Center (DKFZ), Division of Clinical Epidemiology, Heidelberg, Germany</mods:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Becker, Nikolaus" sort="Becker, Nikolaus" uniqKey="Becker N" first="Nikolaus" last="Becker">Nikolaus Becker</name>
<affiliation>
<mods:affiliation>German Cancer Research Center (DKFZ), Division of Clinical Epidemiology, Heidelberg, Germany</mods:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Steindorf, Karen" sort="Steindorf, Karen" uniqKey="Steindorf K" first="Karen" last="Steindorf">Karen Steindorf</name>
<affiliation>
<mods:affiliation>German Cancer Research Center (DKFZ), Unit of Environmental Epidemiology, Heidelberg, Germany</mods:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Frentzel Eyme, Rainer" sort="Frentzel Eyme, Rainer" uniqKey="Frentzel Eyme R" first="Rainer" last="Frentzel Eyme">Rainer Frentzel Eyme</name>
<affiliation>
<mods:affiliation>Bremen Institute for Prevention Research and Social Medicine (BIPS), Division of Epidemiology, Bremen, Germany</mods:affiliation>
</affiliation>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:266DD4AE60847656A4B8D1A09E44A3AF1EC871FA</idno>
<date when="2003" year="2003">2003</date>
<idno type="doi">10.1002/ajim.10187</idno>
<idno type="url">https://api.istex.fr/document/266DD4AE60847656A4B8D1A09E44A3AF1EC871FA/fulltext/pdf</idno>
<idno type="wicri:Area/Main/Corpus">000D67</idno>
</publicationStmt>
<sourceDesc>
<biblStruct>
<analytic>
<title level="a" type="main" xml:lang="en">Cancer mortality in a cohort of male German iron foundry workers</title>
<author>
<name sortKey="Adzersen, Karl Einrich" sort="Adzersen, Karl Einrich" uniqKey="Adzersen K" first="Karl Einrich" last="Adzersen">Karl Einrich Adzersen</name>
<affiliation>
<mods:affiliation>German Cancer Research Center (DKFZ), Division of Clinical Epidemiology, Heidelberg, Germany</mods:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Becker, Nikolaus" sort="Becker, Nikolaus" uniqKey="Becker N" first="Nikolaus" last="Becker">Nikolaus Becker</name>
<affiliation>
<mods:affiliation>German Cancer Research Center (DKFZ), Division of Clinical Epidemiology, Heidelberg, Germany</mods:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Steindorf, Karen" sort="Steindorf, Karen" uniqKey="Steindorf K" first="Karen" last="Steindorf">Karen Steindorf</name>
<affiliation>
<mods:affiliation>German Cancer Research Center (DKFZ), Unit of Environmental Epidemiology, Heidelberg, Germany</mods:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Frentzel Eyme, Rainer" sort="Frentzel Eyme, Rainer" uniqKey="Frentzel Eyme R" first="Rainer" last="Frentzel Eyme">Rainer Frentzel Eyme</name>
<affiliation>
<mods:affiliation>Bremen Institute for Prevention Research and Social Medicine (BIPS), Division of Epidemiology, Bremen, Germany</mods:affiliation>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series>
<title level="j">American Journal of Industrial Medicine</title>
<title level="j" type="abbrev">Am. J. Ind. Med.</title>
<idno type="ISSN">0271-3586</idno>
<idno type="eISSN">1097-0274</idno>
<imprint>
<publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<pubPlace>New York</pubPlace>
<date type="published" when="2003-03">2003-03</date>
<biblScope unit="volume">43</biblScope>
<biblScope unit="issue">3</biblScope>
<biblScope unit="page" from="295">295</biblScope>
<biblScope unit="page" to="305">305</biblScope>
</imprint>
<idno type="ISSN">0271-3586</idno>
</series>
<idno type="istex">266DD4AE60847656A4B8D1A09E44A3AF1EC871FA</idno>
<idno type="DOI">10.1002/ajim.10187</idno>
<idno type="ArticleID">AJIM10187</idno>
</biblStruct>
</sourceDesc>
<seriesStmt>
<idno type="ISSN">0271-3586</idno>
</seriesStmt>
</fileDesc>
<profileDesc>
<textClass>
<keywords scheme="KwdEn" xml:lang="en">
<term>cancer</term>
<term>cohort study</term>
<term>epidemiology</term>
<term>iron foundry</term>
<term>larynx</term>
<term>liver</term>
<term>lung</term>
<term>missing death certificates</term>
<term>mortality</term>
<term>mouth</term>
<term>occupation</term>
</keywords>
</textClass>
<langUsage>
<language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">Background: Observations of an increased incidence of cancers of the upper aero‐digestive tract (pharynx, esophagus, larynx, lung) among workers of local German foundries gave rise to concern about a potentially elevated occupational risk of those cancer sites. The purpose of the study was to examine whether occupational exposure in iron foundries increases the risk of cancer. Methods: A historical cohort study of 17,708 male German production workers in 37 iron foundries who were first employed in 1950–1985 with a minimum employment period of 1 year was initiated. Employment and occupational histories were collected. Mortality was compared with that of the German general population during 1950–1993 using a new method for computing the SMR when not all causes of death are available (called SMR*). Results: Mortality from all causes was elevated to SMR = 115.4 (95% confidence interval (CI) = 111.9–119.1), as was for total cancer (SMR* = 123.8, CI = 102.1–152.6), especially cancers of the lung (SMR* = 163.9, CI = 123.9–223.0) and liver (SMR* = 322.5, CI = 149.5–844.8), and diseases of the respiratory system (SMR* = 147.6, CI = 100.4–221.5). Non‐significant elevations of mortality were also found for cancers of the mouth and pharynx (SMR* = 153.5, CI = 82.3–359.8) and larynx (SMR* = 173.1, CI = 85.5–550.5). Mortality from various causes of death was higher among workers with shorter exposure periods than among long‐term employees. The elevated mortality persisted for years and decades after termination of employment. Conclusions: The results provide further evidence for an increased risk of lung cancer and possibly other cancers of the upper aero‐digestive tract among foundry workers. Special attention should be paid to the strongly increased mortality from liver cancer and the mortality pattern among employees having terminated work. Am. J. Ind. Med. 43:295–305, 2003. © 2003 Wiley‐Liss, Inc.</div>
</front>
</TEI>
<istex>
<corpusName>wiley</corpusName>
<author>
<json:item>
<name>Karl‐Heinrich Adzersen MD</name>
<affiliations>
<json:string>German Cancer Research Center (DKFZ), Division of Clinical Epidemiology, Heidelberg, Germany</json:string>
</affiliations>
</json:item>
<json:item>
<name>Nikolaus Becker PhD</name>
<affiliations>
<json:string>German Cancer Research Center (DKFZ), Division of Clinical Epidemiology, Heidelberg, Germany</json:string>
</affiliations>
</json:item>
<json:item>
<name>Karen Steindorf PhD</name>
<affiliations>
<json:string>German Cancer Research Center (DKFZ), Unit of Environmental Epidemiology, Heidelberg, Germany</json:string>
</affiliations>
</json:item>
<json:item>
<name>Rainer Frentzel‐Beyme MD</name>
<affiliations>
<json:string>Bremen Institute for Prevention Research and Social Medicine (BIPS), Division of Epidemiology, Bremen, Germany</json:string>
</affiliations>
</json:item>
</author>
<subject>
<json:item>
<lang>
<json:string>eng</json:string>
</lang>
<value>cancer</value>
</json:item>
<json:item>
<lang>
<json:string>eng</json:string>
</lang>
<value>cohort study</value>
</json:item>
<json:item>
<lang>
<json:string>eng</json:string>
</lang>
<value>epidemiology</value>
</json:item>
<json:item>
<lang>
<json:string>eng</json:string>
</lang>
<value>iron foundry</value>
</json:item>
<json:item>
<lang>
<json:string>eng</json:string>
</lang>
<value>larynx</value>
</json:item>
<json:item>
<lang>
<json:string>eng</json:string>
</lang>
<value>liver</value>
</json:item>
<json:item>
<lang>
<json:string>eng</json:string>
</lang>
<value>lung</value>
</json:item>
<json:item>
<lang>
<json:string>eng</json:string>
</lang>
<value>missing death certificates</value>
</json:item>
<json:item>
<lang>
<json:string>eng</json:string>
</lang>
<value>mortality</value>
</json:item>
<json:item>
<lang>
<json:string>eng</json:string>
</lang>
<value>mouth</value>
</json:item>
<json:item>
<lang>
<json:string>eng</json:string>
</lang>
<value>occupation</value>
</json:item>
</subject>
<language>
<json:string>eng</json:string>
</language>
<abstract>Background: Observations of an increased incidence of cancers of the upper aero‐digestive tract (pharynx, esophagus, larynx, lung) among workers of local German foundries gave rise to concern about a potentially elevated occupational risk of those cancer sites. The purpose of the study was to examine whether occupational exposure in iron foundries increases the risk of cancer. Methods: A historical cohort study of 17,708 male German production workers in 37 iron foundries who were first employed in 1950–1985 with a minimum employment period of 1 year was initiated. Employment and occupational histories were collected. Mortality was compared with that of the German general population during 1950–1993 using a new method for computing the SMR when not all causes of death are available (called SMR*). Results: Mortality from all causes was elevated to SMR = 115.4 (95% confidence interval (CI) = 111.9–119.1), as was for total cancer (SMR* = 123.8, CI = 102.1–152.6), especially cancers of the lung (SMR* = 163.9, CI = 123.9–223.0) and liver (SMR* = 322.5, CI = 149.5–844.8), and diseases of the respiratory system (SMR* = 147.6, CI = 100.4–221.5). Non‐significant elevations of mortality were also found for cancers of the mouth and pharynx (SMR* = 153.5, CI = 82.3–359.8) and larynx (SMR* = 173.1, CI = 85.5–550.5). Mortality from various causes of death was higher among workers with shorter exposure periods than among long‐term employees. The elevated mortality persisted for years and decades after termination of employment. Conclusions: The results provide further evidence for an increased risk of lung cancer and possibly other cancers of the upper aero‐digestive tract among foundry workers. Special attention should be paid to the strongly increased mortality from liver cancer and the mortality pattern among employees having terminated work. Am. J. Ind. Med. 43:295–305, 2003. © 2003 Wiley‐Liss, Inc.</abstract>
<qualityIndicators>
<score>8</score>
<pdfVersion>1.3</pdfVersion>
<pdfPageSize>592 x 789 pts</pdfPageSize>
<refBibsNative>true</refBibsNative>
<keywordCount>11</keywordCount>
<abstractCharCount>1921</abstractCharCount>
<pdfWordCount>5472</pdfWordCount>
<pdfCharCount>39742</pdfCharCount>
<pdfPageCount>11</pdfPageCount>
<abstractWordCount>269</abstractWordCount>
</qualityIndicators>
<title>Cancer mortality in a cohort of male German iron foundry workers</title>
<genre>
<json:string>article</json:string>
</genre>
<host>
<volume>43</volume>
<pages>
<total>11</total>
<last>305</last>
<first>295</first>
</pages>
<issn>
<json:string>0271-3586</json:string>
</issn>
<issue>3</issue>
<subject>
<json:item>
<value>Article</value>
</json:item>
</subject>
<genre></genre>
<language>
<json:string>unknown</json:string>
</language>
<eissn>
<json:string>1097-0274</json:string>
</eissn>
<title>American Journal of Industrial Medicine</title>
<doi>
<json:string>10.1002/(ISSN)1097-0274</json:string>
</doi>
</host>
<publicationDate>2003</publicationDate>
<copyrightDate>2003</copyrightDate>
<doi>
<json:string>10.1002/ajim.10187</json:string>
</doi>
<id>266DD4AE60847656A4B8D1A09E44A3AF1EC871FA</id>
<fulltext>
<json:item>
<original>true</original>
<mimetype>application/pdf</mimetype>
<extension>pdf</extension>
<uri>https://api.istex.fr/document/266DD4AE60847656A4B8D1A09E44A3AF1EC871FA/fulltext/pdf</uri>
</json:item>
<json:item>
<original>false</original>
<mimetype>application/zip</mimetype>
<extension>zip</extension>
<uri>https://api.istex.fr/document/266DD4AE60847656A4B8D1A09E44A3AF1EC871FA/fulltext/zip</uri>
</json:item>
<istex:fulltextTEI uri="https://api.istex.fr/document/266DD4AE60847656A4B8D1A09E44A3AF1EC871FA/fulltext/tei">
<teiHeader>
<fileDesc>
<titleStmt>
<title level="a" type="main" xml:lang="en">Cancer mortality in a cohort of male German iron foundry workers</title>
</titleStmt>
<publicationStmt>
<authority>ISTEX</authority>
<publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<pubPlace>New York</pubPlace>
<availability>
<p>WILEY</p>
</availability>
<date>2003</date>
</publicationStmt>
<notesStmt>
<note>Union of the Employer's Compensation Funds of the Iron and Metal Industries (Arbeitsgemeinschaft der Eisen‐ und Metall‐Berufsgenossenschaften)</note>
</notesStmt>
<sourceDesc>
<biblStruct type="inbook">
<analytic>
<title level="a" type="main" xml:lang="en">Cancer mortality in a cohort of male German iron foundry workers</title>
<author>
<persName>
<forename type="first">Karl‐Heinrich</forename>
<surname>Adzersen</surname>
</persName>
<roleName type="degree">MD</roleName>
<affiliation>German Cancer Research Center (DKFZ), Division of Clinical Epidemiology, Heidelberg, Germany</affiliation>
</author>
<author>
<persName>
<forename type="first">Nikolaus</forename>
<surname>Becker</surname>
</persName>
<roleName type="degree">PhD</roleName>
<note type="correspondence">
<p>Correspondence: German Cancer Research Center, Division of Clinical Epidemiology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.</p>
</note>
<affiliation>German Cancer Research Center (DKFZ), Division of Clinical Epidemiology, Heidelberg, Germany</affiliation>
</author>
<author>
<persName>
<forename type="first">Karen</forename>
<surname>Steindorf</surname>
</persName>
<roleName type="degree">PhD</roleName>
<affiliation>German Cancer Research Center (DKFZ), Unit of Environmental Epidemiology, Heidelberg, Germany</affiliation>
</author>
<author>
<persName>
<forename type="first">Rainer</forename>
<surname>Frentzel‐Beyme</surname>
</persName>
<roleName type="degree">MD</roleName>
<affiliation>Bremen Institute for Prevention Research and Social Medicine (BIPS), Division of Epidemiology, Bremen, Germany</affiliation>
</author>
</analytic>
<monogr>
<title level="j">American Journal of Industrial Medicine</title>
<title level="j" type="abbrev">Am. J. Ind. Med.</title>
<idno type="pISSN">0271-3586</idno>
<idno type="eISSN">1097-0274</idno>
<idno type="DOI">10.1002/(ISSN)1097-0274</idno>
<imprint>
<publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<pubPlace>New York</pubPlace>
<date type="published" when="2003-03"></date>
<biblScope unit="volume">43</biblScope>
<biblScope unit="issue">3</biblScope>
<biblScope unit="page" from="295">295</biblScope>
<biblScope unit="page" to="305">305</biblScope>
</imprint>
</monogr>
<idno type="istex">266DD4AE60847656A4B8D1A09E44A3AF1EC871FA</idno>
<idno type="DOI">10.1002/ajim.10187</idno>
<idno type="ArticleID">AJIM10187</idno>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc>
<creation>
<date>2003</date>
</creation>
<langUsage>
<language ident="en">en</language>
</langUsage>
<abstract xml:lang="en">
<p>Background: Observations of an increased incidence of cancers of the upper aero‐digestive tract (pharynx, esophagus, larynx, lung) among workers of local German foundries gave rise to concern about a potentially elevated occupational risk of those cancer sites. The purpose of the study was to examine whether occupational exposure in iron foundries increases the risk of cancer. Methods: A historical cohort study of 17,708 male German production workers in 37 iron foundries who were first employed in 1950–1985 with a minimum employment period of 1 year was initiated. Employment and occupational histories were collected. Mortality was compared with that of the German general population during 1950–1993 using a new method for computing the SMR when not all causes of death are available (called SMR*). Results: Mortality from all causes was elevated to SMR = 115.4 (95% confidence interval (CI) = 111.9–119.1), as was for total cancer (SMR* = 123.8, CI = 102.1–152.6), especially cancers of the lung (SMR* = 163.9, CI = 123.9–223.0) and liver (SMR* = 322.5, CI = 149.5–844.8), and diseases of the respiratory system (SMR* = 147.6, CI = 100.4–221.5). Non‐significant elevations of mortality were also found for cancers of the mouth and pharynx (SMR* = 153.5, CI = 82.3–359.8) and larynx (SMR* = 173.1, CI = 85.5–550.5). Mortality from various causes of death was higher among workers with shorter exposure periods than among long‐term employees. The elevated mortality persisted for years and decades after termination of employment. Conclusions: The results provide further evidence for an increased risk of lung cancer and possibly other cancers of the upper aero‐digestive tract among foundry workers. Special attention should be paid to the strongly increased mortality from liver cancer and the mortality pattern among employees having terminated work. Am. J. Ind. Med. 43:295–305, 2003. © 2003 Wiley‐Liss, Inc.</p>
</abstract>
<textClass xml:lang="en">
<keywords scheme="keyword">
<list>
<head>Keywords</head>
<item>
<term>cancer</term>
</item>
<item>
<term>cohort study</term>
</item>
<item>
<term>epidemiology</term>
</item>
<item>
<term>iron foundry</term>
</item>
<item>
<term>larynx</term>
</item>
<item>
<term>liver</term>
</item>
<item>
<term>lung</term>
</item>
<item>
<term>missing death certificates</term>
</item>
<item>
<term>mortality</term>
</item>
<item>
<term>mouth</term>
</item>
<item>
<term>occupation</term>
</item>
</list>
</keywords>
</textClass>
<textClass>
<keywords scheme="Journal Subject">
<list>
<head>article category</head>
<item>
<term>Article</term>
</item>
</list>
</keywords>
</textClass>
</profileDesc>
<revisionDesc>
<change when="2002-10-22">Registration</change>
<change when="2003-03">Published</change>
</revisionDesc>
</teiHeader>
</istex:fulltextTEI>
<json:item>
<original>false</original>
<mimetype>text/plain</mimetype>
<extension>txt</extension>
<uri>https://api.istex.fr/document/266DD4AE60847656A4B8D1A09E44A3AF1EC871FA/fulltext/txt</uri>
</json:item>
</fulltext>
<metadata>
<istex:metadataXml wicri:clean="Wiley, elements deleted: body">
<istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration>
<istex:document>
<component version="2.0" type="serialArticle" xml:lang="en">
<header>
<publicationMeta level="product">
<publisherInfo>
<publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName>
<publisherLoc>New York</publisherLoc>
</publisherInfo>
<doi registered="yes">10.1002/(ISSN)1097-0274</doi>
<issn type="print">0271-3586</issn>
<issn type="electronic">1097-0274</issn>
<idGroup>
<id type="product" value="AJIM"></id>
</idGroup>
<titleGroup>
<title type="main" xml:lang="en" sort="AMERICAN JOURNAL OF INDUSTRIAL MEDICINE">American Journal of Industrial Medicine</title>
<title type="short">Am. J. Ind. Med.</title>
</titleGroup>
</publicationMeta>
<publicationMeta level="part" position="30">
<doi origin="wiley" registered="yes">10.1002/ajim.v43:3</doi>
<numberingGroup>
<numbering type="journalVolume" number="43">43</numbering>
<numbering type="journalIssue">3</numbering>
</numberingGroup>
<coverDate startDate="2003-03">March 2003</coverDate>
</publicationMeta>
<publicationMeta level="unit" type="article" position="8" status="forIssue">
<doi origin="wiley" registered="yes">10.1002/ajim.10187</doi>
<idGroup>
<id type="unit" value="AJIM10187"></id>
</idGroup>
<countGroup>
<count type="pageTotal" number="11"></count>
</countGroup>
<titleGroup>
<title type="articleCategory">Article</title>
<title type="tocHeading1">Articles</title>
</titleGroup>
<copyright ownership="publisher">Copyright © 2003 Wiley‐Liss, Inc.</copyright>
<eventGroup>
<event type="manuscriptAccepted" date="2002-10-22"></event>
<event type="firstOnline" date="2003-02-19"></event>
<event type="publishedOnlineFinalForm" date="2003-02-19"></event>
<event type="xmlConverted" agent="Converter:JWSART34_TO_WML3G version:2.3.18.1 mode:FullText source:HeaderRef result:HeaderRef" date="2010-09-09"></event>
<event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-01-05"></event>
<event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-14"></event>
</eventGroup>
<numberingGroup>
<numbering type="pageFirst">295</numbering>
<numbering type="pageLast">305</numbering>
</numberingGroup>
<correspondenceTo>German Cancer Research Center, Division of Clinical Epidemiology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.</correspondenceTo>
<linkGroup>
<link type="toTypesetVersion" href="file:AJIM.AJIM10187.pdf"></link>
</linkGroup>
</publicationMeta>
<contentMeta>
<countGroup>
<count type="figureTotal" number="0"></count>
<count type="tableTotal" number="9"></count>
<count type="referenceTotal" number="41"></count>
<count type="wordTotal" number="1201"></count>
</countGroup>
<titleGroup>
<title type="main" xml:lang="en">Cancer mortality in a cohort of male German iron foundry workers</title>
<title type="short" xml:lang="en">Cancer Mortality in Iron Foundry Workers</title>
</titleGroup>
<creators>
<creator xml:id="au1" creatorRole="author" affiliationRef="#af1">
<personName>
<givenNames>Karl‐Heinrich</givenNames>
<familyName>Adzersen</familyName>
<degrees>MD</degrees>
</personName>
</creator>
<creator xml:id="au2" creatorRole="author" affiliationRef="#af1" corresponding="yes">
<personName>
<givenNames>Nikolaus</givenNames>
<familyName>Becker</familyName>
<degrees>PhD</degrees>
</personName>
<contactDetails>
<email>n.becker@dkfz.de</email>
</contactDetails>
</creator>
<creator xml:id="au3" creatorRole="author" affiliationRef="#af2">
<personName>
<givenNames>Karen</givenNames>
<familyName>Steindorf</familyName>
<degrees>PhD</degrees>
</personName>
</creator>
<creator xml:id="au4" creatorRole="author" affiliationRef="#af3">
<personName>
<givenNames>Rainer</givenNames>
<familyName>Frentzel‐Beyme</familyName>
<degrees>MD</degrees>
</personName>
</creator>
</creators>
<affiliationGroup>
<affiliation xml:id="af1" countryCode="DE" type="organization">
<unparsedAffiliation>German Cancer Research Center (DKFZ), Division of Clinical Epidemiology, Heidelberg, Germany</unparsedAffiliation>
</affiliation>
<affiliation xml:id="af2" countryCode="DE" type="organization">
<unparsedAffiliation>German Cancer Research Center (DKFZ), Unit of Environmental Epidemiology, Heidelberg, Germany</unparsedAffiliation>
</affiliation>
<affiliation xml:id="af3" countryCode="DE" type="organization">
<unparsedAffiliation>Bremen Institute for Prevention Research and Social Medicine (BIPS), Division of Epidemiology, Bremen, Germany</unparsedAffiliation>
</affiliation>
</affiliationGroup>
<keywordGroup xml:lang="en" type="author">
<keyword xml:id="kwd1">cancer</keyword>
<keyword xml:id="kwd2">cohort study</keyword>
<keyword xml:id="kwd3">epidemiology</keyword>
<keyword xml:id="kwd4">iron foundry</keyword>
<keyword xml:id="kwd5">larynx</keyword>
<keyword xml:id="kwd6">liver</keyword>
<keyword xml:id="kwd7">lung</keyword>
<keyword xml:id="kwd8">missing death certificates</keyword>
<keyword xml:id="kwd9">mortality</keyword>
<keyword xml:id="kwd10">mouth</keyword>
<keyword xml:id="kwd11">occupation</keyword>
</keywordGroup>
<fundingInfo>
<fundingAgency>Union of the Employer's Compensation Funds of the Iron and Metal Industries (Arbeitsgemeinschaft der Eisen‐ und Metall‐Berufsgenossenschaften)</fundingAgency>
</fundingInfo>
<abstractGroup>
<abstract type="main" xml:lang="en">
<title type="main">Abstract</title>
<section xml:id="abs1-1">
<title type="main">Background</title>
<p>Observations of an increased incidence of cancers of the upper aero‐digestive tract (pharynx, esophagus, larynx, lung) among workers of local German foundries gave rise to concern about a potentially elevated occupational risk of those cancer sites. The purpose of the study was to examine whether occupational exposure in iron foundries increases the risk of cancer.</p>
</section>
<section xml:id="abs1-2">
<title type="main">Methods</title>
<p>A historical cohort study of 17,708 male German production workers in 37 iron foundries who were first employed in 1950–1985 with a minimum employment period of 1 year was initiated. Employment and occupational histories were collected. Mortality was compared with that of the German general population during 1950–1993 using a new method for computing the SMR when not all causes of death are available (called SMR*).</p>
</section>
<section xml:id="abs1-3">
<title type="main">Results</title>
<p>Mortality from all causes was elevated to SMR = 115.4 (95% confidence interval (CI) = 111.9–119.1), as was for total cancer (SMR* = 123.8, CI = 102.1–152.6), especially cancers of the lung (SMR* = 163.9, CI = 123.9–223.0) and liver (SMR* = 322.5, CI = 149.5–844.8), and diseases of the respiratory system (SMR* = 147.6, CI = 100.4–221.5). Non‐significant elevations of mortality were also found for cancers of the mouth and pharynx (SMR* = 153.5, CI = 82.3–359.8) and larynx (SMR* = 173.1, CI = 85.5–550.5). Mortality from various causes of death was higher among workers with shorter exposure periods than among long‐term employees. The elevated mortality persisted for years and decades after termination of employment.</p>
</section>
<section xml:id="abs1-4">
<title type="main">Conclusions</title>
<p>The results provide further evidence for an increased risk of lung cancer and possibly other cancers of the upper aero‐digestive tract among foundry workers. Special attention should be paid to the strongly increased mortality from liver cancer and the mortality pattern among employees having terminated work. Am. J. Ind. Med. 43:295–305, 2003. © 2003 Wiley‐Liss, Inc.</p>
</section>
</abstract>
</abstractGroup>
</contentMeta>
</header>
</component>
</istex:document>
</istex:metadataXml>
<mods version="3.6">
<titleInfo lang="en">
<title>Cancer mortality in a cohort of male German iron foundry workers</title>
</titleInfo>
<titleInfo type="abbreviated" lang="en">
<title>Cancer Mortality in Iron Foundry Workers</title>
</titleInfo>
<titleInfo type="alternative" contentType="CDATA" lang="en">
<title>Cancer mortality in a cohort of male German iron foundry workers</title>
</titleInfo>
<name type="personal">
<namePart type="given">Karl‐Heinrich</namePart>
<namePart type="family">Adzersen</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>German Cancer Research Center (DKFZ), Division of Clinical Epidemiology, Heidelberg, Germany</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Nikolaus</namePart>
<namePart type="family">Becker</namePart>
<namePart type="termsOfAddress">PhD</namePart>
<affiliation>German Cancer Research Center (DKFZ), Division of Clinical Epidemiology, Heidelberg, Germany</affiliation>
<description>Correspondence: German Cancer Research Center, Division of Clinical Epidemiology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.</description>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Karen</namePart>
<namePart type="family">Steindorf</namePart>
<namePart type="termsOfAddress">PhD</namePart>
<affiliation>German Cancer Research Center (DKFZ), Unit of Environmental Epidemiology, Heidelberg, Germany</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Rainer</namePart>
<namePart type="family">Frentzel‐Beyme</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Bremen Institute for Prevention Research and Social Medicine (BIPS), Division of Epidemiology, Bremen, Germany</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<typeOfResource>text</typeOfResource>
<genre type="article" displayLabel="article"></genre>
<originInfo>
<publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<place>
<placeTerm type="text">New York</placeTerm>
</place>
<dateIssued encoding="w3cdtf">2003-03</dateIssued>
<dateValid encoding="w3cdtf">2002-10-22</dateValid>
<copyrightDate encoding="w3cdtf">2003</copyrightDate>
</originInfo>
<language>
<languageTerm type="code" authority="rfc3066">en</languageTerm>
<languageTerm type="code" authority="iso639-2b">eng</languageTerm>
</language>
<physicalDescription>
<internetMediaType>text/html</internetMediaType>
<extent unit="tables">9</extent>
<extent unit="references">41</extent>
<extent unit="words">1201</extent>
</physicalDescription>
<abstract lang="en">Background: Observations of an increased incidence of cancers of the upper aero‐digestive tract (pharynx, esophagus, larynx, lung) among workers of local German foundries gave rise to concern about a potentially elevated occupational risk of those cancer sites. The purpose of the study was to examine whether occupational exposure in iron foundries increases the risk of cancer. Methods: A historical cohort study of 17,708 male German production workers in 37 iron foundries who were first employed in 1950–1985 with a minimum employment period of 1 year was initiated. Employment and occupational histories were collected. Mortality was compared with that of the German general population during 1950–1993 using a new method for computing the SMR when not all causes of death are available (called SMR*). Results: Mortality from all causes was elevated to SMR = 115.4 (95% confidence interval (CI) = 111.9–119.1), as was for total cancer (SMR* = 123.8, CI = 102.1–152.6), especially cancers of the lung (SMR* = 163.9, CI = 123.9–223.0) and liver (SMR* = 322.5, CI = 149.5–844.8), and diseases of the respiratory system (SMR* = 147.6, CI = 100.4–221.5). Non‐significant elevations of mortality were also found for cancers of the mouth and pharynx (SMR* = 153.5, CI = 82.3–359.8) and larynx (SMR* = 173.1, CI = 85.5–550.5). Mortality from various causes of death was higher among workers with shorter exposure periods than among long‐term employees. The elevated mortality persisted for years and decades after termination of employment. Conclusions: The results provide further evidence for an increased risk of lung cancer and possibly other cancers of the upper aero‐digestive tract among foundry workers. Special attention should be paid to the strongly increased mortality from liver cancer and the mortality pattern among employees having terminated work. Am. J. Ind. Med. 43:295–305, 2003. © 2003 Wiley‐Liss, Inc.</abstract>
<note type="funding">Union of the Employer's Compensation Funds of the Iron and Metal Industries (Arbeitsgemeinschaft der Eisen‐ und Metall‐Berufsgenossenschaften)</note>
<subject lang="en">
<genre>Keywords</genre>
<topic>cancer</topic>
<topic>cohort study</topic>
<topic>epidemiology</topic>
<topic>iron foundry</topic>
<topic>larynx</topic>
<topic>liver</topic>
<topic>lung</topic>
<topic>missing death certificates</topic>
<topic>mortality</topic>
<topic>mouth</topic>
<topic>occupation</topic>
</subject>
<relatedItem type="host">
<titleInfo>
<title>American Journal of Industrial Medicine</title>
</titleInfo>
<titleInfo type="abbreviated">
<title>Am. J. Ind. Med.</title>
</titleInfo>
<genre type="Journal">journal</genre>
<subject>
<genre>article category</genre>
<topic>Article</topic>
</subject>
<identifier type="ISSN">0271-3586</identifier>
<identifier type="eISSN">1097-0274</identifier>
<identifier type="DOI">10.1002/(ISSN)1097-0274</identifier>
<identifier type="PublisherID">AJIM</identifier>
<part>
<date>2003</date>
<detail type="volume">
<caption>vol.</caption>
<number>43</number>
</detail>
<detail type="issue">
<caption>no.</caption>
<number>3</number>
</detail>
<extent unit="pages">
<start>295</start>
<end>305</end>
<total>11</total>
</extent>
</part>
</relatedItem>
<identifier type="istex">266DD4AE60847656A4B8D1A09E44A3AF1EC871FA</identifier>
<identifier type="DOI">10.1002/ajim.10187</identifier>
<identifier type="ArticleID">AJIM10187</identifier>
<accessCondition type="use and reproduction" contentType="copyright">Copyright © 2003 Wiley‐Liss, Inc.</accessCondition>
<recordInfo>
<recordContentSource>WILEY</recordContentSource>
<recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin>
</recordInfo>
</mods>
</metadata>
<serie></serie>
</istex>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Musique/explor/SchutzV1/Data/Main/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000D67 | SxmlIndent | more

Ou

HfdSelect -h $EXPLOR_AREA/Data/Main/Corpus/biblio.hfd -nk 000D67 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Musique
   |area=    SchutzV1
   |flux=    Main
   |étape=   Corpus
   |type=    RBID
   |clé=     ISTEX:266DD4AE60847656A4B8D1A09E44A3AF1EC871FA
   |texte=   Cancer mortality in a cohort of male German iron foundry workers
}}

Wicri

This area was generated with Dilib version V0.6.38.
Data generation: Mon Feb 8 17:34:10 2021. Site generation: Mon Feb 8 17:41:23 2021