A 74-bp Promoter of the Tnp2 Gene Confers Testis- and Spermatid-Specific Expression in Transgenic Mice
Identifieur interne : 000386 ( Main/Corpus ); précédent : 000385; suivant : 000387A 74-bp Promoter of the Tnp2 Gene Confers Testis- and Spermatid-Specific Expression in Transgenic Mice
Auteurs : Özlem Topaloglu ; Gregor Schlüter ; Karim Nayernia ; Wolfgang EngelSource :
- Biochemical and Biophysical Research Communications [ 0006-291X ] ; 2001.
English descriptors
Abstract
During the final stages of spermatogenesis, round spermatids undergo several morphological, biochemical, and physiological modifications which result in the formation of mature spermatozoa. One of these is the nuclear condensation, achieved by the replacement of somatic-type and testis-specific histones by transition proteins and protamines leading to cessation of transcription several days before the completion of spermiogenesis. Therefore, a strict temporal and stage-specific gene expression is necessary for the correct differentiation of round spermatids into mature spermatozoa. In this study, the 5′ regulatory region of rat Tnp2 gene was investigated by primer extension analysis and transgenic mice study. Primer extension analysis revealed a transcription start site which lies 70 bp upstream of the translation start codon. By transgenic mice studies, we demonstrated that a 147-bp 5′ untranslated region corresponding to the region −74 to +73 is sufficient to confer testis- and spermatid-specific expression of rat Tnp2 gene.
Url:
DOI: 10.1006/bbrc.2001.5999
Links to Exploration step
ISTEX:946E63187BADFEB705E30243ADE8B69FBD103822Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">A 74-bp Promoter of the Tnp2 Gene Confers Testis- and Spermatid-Specific Expression in Transgenic Mice</title><author><name sortKey="Topaloglu, Ozlem" sort="Topaloglu, Ozlem" uniqKey="Topaloglu O" first="Özlem" last="Topaloglu">Özlem Topaloglu</name><affiliation><mods:affiliation>Institute of Human Genetics, University of Göttingen, Heinrich-Düker-Weg 12, 37073, Göttingen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Schluter, Gregor" sort="Schluter, Gregor" uniqKey="Schluter G" first="Gregor" last="Schlüter">Gregor Schlüter</name><affiliation><mods:affiliation>Institute of Human Genetics, University of Göttingen, Heinrich-Düker-Weg 12, 37073, Göttingen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Nayernia, Karim" sort="Nayernia, Karim" uniqKey="Nayernia K" first="Karim" last="Nayernia">Karim Nayernia</name><affiliation><mods:affiliation>Institute of Human Genetics, University of Göttingen, Heinrich-Düker-Weg 12, 37073, Göttingen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Engel, Wolfgang" sort="Engel, Wolfgang" uniqKey="Engel W" first="Wolfgang" last="Engel">Wolfgang Engel</name><affiliation><mods:affiliation>Institute of Human Genetics, University of Göttingen, Heinrich-Düker-Weg 12, 37073, Göttingen, Germany</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:946E63187BADFEB705E30243ADE8B69FBD103822</idno><date when="2001" year="2001">2001</date><idno type="doi">10.1006/bbrc.2001.5999</idno><idno type="url">https://api.istex.fr/document/946E63187BADFEB705E30243ADE8B69FBD103822/fulltext/pdf</idno><idno type="wicri:Area/Main/Corpus">000386</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">A 74-bp Promoter of the Tnp2 Gene Confers Testis- and Spermatid-Specific Expression in Transgenic Mice</title><author><name sortKey="Topaloglu, Ozlem" sort="Topaloglu, Ozlem" uniqKey="Topaloglu O" first="Özlem" last="Topaloglu">Özlem Topaloglu</name><affiliation><mods:affiliation>Institute of Human Genetics, University of Göttingen, Heinrich-Düker-Weg 12, 37073, Göttingen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Schluter, Gregor" sort="Schluter, Gregor" uniqKey="Schluter G" first="Gregor" last="Schlüter">Gregor Schlüter</name><affiliation><mods:affiliation>Institute of Human Genetics, University of Göttingen, Heinrich-Düker-Weg 12, 37073, Göttingen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Nayernia, Karim" sort="Nayernia, Karim" uniqKey="Nayernia K" first="Karim" last="Nayernia">Karim Nayernia</name><affiliation><mods:affiliation>Institute of Human Genetics, University of Göttingen, Heinrich-Düker-Weg 12, 37073, Göttingen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Engel, Wolfgang" sort="Engel, Wolfgang" uniqKey="Engel W" first="Wolfgang" last="Engel">Wolfgang Engel</name><affiliation><mods:affiliation>Institute of Human Genetics, University of Göttingen, Heinrich-Düker-Weg 12, 37073, Göttingen, Germany</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Biochemical and Biophysical Research Communications</title><title level="j" type="abbrev">YBBRC</title><idno type="ISSN">0006-291X</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="2001">2001</date><biblScope unit="volume">289</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="597">597</biblScope><biblScope unit="page" to="601">601</biblScope></imprint><idno type="ISSN">0006-291X</idno></series><idno type="istex">946E63187BADFEB705E30243ADE8B69FBD103822</idno><idno type="DOI">10.1006/bbrc.2001.5999</idno><idno type="PII">S0006-291X(01)95999-6</idno><idno type="ArticleID">95999</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0006-291X</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>RNA-binding protein</term><term>transgenic mice</term><term>transition protein 2</term><term>translational control</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">During the final stages of spermatogenesis, round spermatids undergo several morphological, biochemical, and physiological modifications which result in the formation of mature spermatozoa. One of these is the nuclear condensation, achieved by the replacement of somatic-type and testis-specific histones by transition proteins and protamines leading to cessation of transcription several days before the completion of spermiogenesis. Therefore, a strict temporal and stage-specific gene expression is necessary for the correct differentiation of round spermatids into mature spermatozoa. In this study, the 5′ regulatory region of rat Tnp2 gene was investigated by primer extension analysis and transgenic mice study. Primer extension analysis revealed a transcription start site which lies 70 bp upstream of the translation start codon. By transgenic mice studies, we demonstrated that a 147-bp 5′ untranslated region corresponding to the region −74 to +73 is sufficient to confer testis- and spermatid-specific expression of rat Tnp2 gene.</div></front></TEI><istex><corpusName>elsevier</corpusName><author><json:item><name>Özlem Topaloglu</name><affiliations><json:string>Institute of Human Genetics, University of Göttingen, Heinrich-Düker-Weg 12, 37073, Göttingen, Germany</json:string></affiliations></json:item><json:item><name>Gregor Schlüter</name><affiliations><json:string>Institute of Human Genetics, University of Göttingen, Heinrich-Düker-Weg 12, 37073, Göttingen, Germany</json:string></affiliations></json:item><json:item><name>Karim Nayernia</name><affiliations><json:string>Institute of Human Genetics, University of Göttingen, Heinrich-Düker-Weg 12, 37073, Göttingen, Germany</json:string></affiliations></json:item><json:item><name>Wolfgang Engel</name><affiliations><json:string>Institute of Human Genetics, University of Göttingen, Heinrich-Düker-Weg 12, 37073, Göttingen, Germany</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>translational control</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>transgenic mice</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>RNA-binding protein</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>transition protein 2</value></json:item></subject><language><json:string>eng</json:string></language><abstract>During the final stages of spermatogenesis, round spermatids undergo several morphological, biochemical, and physiological modifications which result in the formation of mature spermatozoa. One of these is the nuclear condensation, achieved by the replacement of somatic-type and testis-specific histones by transition proteins and protamines leading to cessation of transcription several days before the completion of spermiogenesis. Therefore, a strict temporal and stage-specific gene expression is necessary for the correct differentiation of round spermatids into mature spermatozoa. In this study, the 5′ regulatory region of rat Tnp2 gene was investigated by primer extension analysis and transgenic mice study. Primer extension analysis revealed a transcription start site which lies 70 bp upstream of the translation start codon. By transgenic mice studies, we demonstrated that a 147-bp 5′ untranslated region corresponding to the region −74 to +73 is sufficient to confer testis- and spermatid-specific expression of rat Tnp2 gene.</abstract><qualityIndicators><score>4.994</score><pdfVersion>1.4</pdfVersion><pdfPageSize>546 x 742 pts</pdfPageSize><refBibsNative>true</refBibsNative><keywordCount>4</keywordCount><abstractCharCount>1042</abstractCharCount><pdfWordCount>2742</pdfWordCount><pdfCharCount>16464</pdfCharCount><pdfPageCount>5</pdfPageCount><abstractWordCount>146</abstractWordCount></qualityIndicators><title>A 74-bp Promoter of the Tnp2 Gene Confers Testis- and Spermatid-Specific Expression in Transgenic Mice</title><pii><json:string>S0006-291X(01)95999-6</json:string></pii><genre><json:string>research-article</json:string></genre><host><volume>289</volume><pii><json:string>S0006-291X(00)X0305-1</json:string></pii><pages><last>601</last><first>597</first></pages><issn><json:string>0006-291X</json:string></issn><issue>2</issue><genre></genre><language><json:string>unknown</json:string></language><title>Biochemical and Biophysical Research Communications</title><publicationDate>2001</publicationDate></host><publicationDate>2001</publicationDate><copyrightDate>2001</copyrightDate><doi><json:string>10.1006/bbrc.2001.5999</json:string></doi><id>946E63187BADFEB705E30243ADE8B69FBD103822</id><fulltext><json:item><original>true</original><mimetype>application/pdf</mimetype><extension>pdf</extension><uri>https://api.istex.fr/document/946E63187BADFEB705E30243ADE8B69FBD103822/fulltext/pdf</uri></json:item><json:item><original>false</original><mimetype>application/zip</mimetype><extension>zip</extension><uri>https://api.istex.fr/document/946E63187BADFEB705E30243ADE8B69FBD103822/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/946E63187BADFEB705E30243ADE8B69FBD103822/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">A 74-bp Promoter of the Tnp2 Gene Confers Testis- and Spermatid-Specific Expression in Transgenic Mice</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>ELSEVIER</publisher><availability><p>ELSEVIER</p></availability><date>2001</date></publicationStmt><notesStmt><note type="content">Section title: Regular Article</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">A 74-bp Promoter of the Tnp2 Gene Confers Testis- and Spermatid-Specific Expression in Transgenic Mice</title><author><persName><forename type="first">Özlem</forename><surname>Topaloglu</surname></persName><note type="biography">Both authors contributed equally to this work.</note><affiliation>Both authors contributed equally to this work.</affiliation><affiliation>Institute of Human Genetics, University of Göttingen, Heinrich-Düker-Weg 12, 37073, Göttingen, Germany</affiliation></author><author><persName><forename type="first">Gregor</forename><surname>Schlüter</surname></persName><note type="biography">Both authors contributed equally to this work.</note><affiliation>Both authors contributed equally to this work.</affiliation><affiliation>Institute of Human Genetics, University of Göttingen, Heinrich-Düker-Weg 12, 37073, Göttingen, Germany</affiliation></author><author><persName><forename type="first">Karim</forename><surname>Nayernia</surname></persName><affiliation>Institute of Human Genetics, University of Göttingen, Heinrich-Düker-Weg 12, 37073, Göttingen, Germany</affiliation></author><author><persName><forename type="first">Wolfgang</forename><surname>Engel</surname></persName><affiliation>Institute of Human Genetics, University of Göttingen, Heinrich-Düker-Weg 12, 37073, Göttingen, Germany</affiliation></author></analytic><monogr><title level="j">Biochemical and Biophysical Research Communications</title><title level="j" type="abbrev">YBBRC</title><idno type="pISSN">0006-291X</idno><idno type="PII">S0006-291X(00)X0305-1</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="2001"></date><biblScope unit="volume">289</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="597">597</biblScope><biblScope unit="page" to="601">601</biblScope></imprint></monogr><idno type="istex">946E63187BADFEB705E30243ADE8B69FBD103822</idno><idno type="DOI">10.1006/bbrc.2001.5999</idno><idno type="PII">S0006-291X(01)95999-6</idno><idno type="ArticleID">95999</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2001</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>During the final stages of spermatogenesis, round spermatids undergo several morphological, biochemical, and physiological modifications which result in the formation of mature spermatozoa. One of these is the nuclear condensation, achieved by the replacement of somatic-type and testis-specific histones by transition proteins and protamines leading to cessation of transcription several days before the completion of spermiogenesis. Therefore, a strict temporal and stage-specific gene expression is necessary for the correct differentiation of round spermatids into mature spermatozoa. In this study, the 5′ regulatory region of rat Tnp2 gene was investigated by primer extension analysis and transgenic mice study. Primer extension analysis revealed a transcription start site which lies 70 bp upstream of the translation start codon. By transgenic mice studies, we demonstrated that a 147-bp 5′ untranslated region corresponding to the region −74 to +73 is sufficient to confer testis- and spermatid-specific expression of rat Tnp2 gene.</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>translational control</term></item><item><term>transgenic mice</term></item><item><term>RNA-binding protein</term></item><item><term>transition protein 2</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2001-10-22">Received</change><change when="2001">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/946E63187BADFEB705E30243ADE8B69FBD103822/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Elsevier, elements deleted: tail"><istex:xmlDeclaration>version="1.0" encoding="UTF-8"</istex:xmlDeclaration><istex:docType PUBLIC="-//ES//DTD journal article DTD version 4.5.2//EN//XML" URI="art452.dtd" name="istex:docType"></istex:docType><istex:document><converted-article version="4.5.2" docsubtype="fla" xml:lang="en"><item-info><jid>YBBRC</jid><aid>95999</aid><ce:pii>S0006-291X(01)95999-6</ce:pii><ce:doi>10.1006/bbrc.2001.5999</ce:doi><ce:copyright type="full-transfer" year="2001">Elsevier Science (USA)</ce:copyright></item-info><head><ce:dochead><ce:textfn>Regular Article</ce:textfn></ce:dochead><ce:title>A 74-bp Promoter of the Tnp2 Gene Confers Testis- and Spermatid-Specific Expression in Transgenic Mice</ce:title><ce:author-group><ce:author><ce:given-name>Özlem</ce:given-name><ce:surname>Topaloglu</ce:surname><ce:cross-ref refid="FN1"><ce:sup loc="post">1</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Gregor</ce:given-name><ce:surname>Schlüter</ce:surname><ce:cross-ref refid="FN1">1</ce:cross-ref><ce:cross-ref refid="FN2"><ce:sup loc="post">2</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Karim</ce:given-name><ce:surname>Nayernia</ce:surname></ce:author><ce:author><ce:given-name>Wolfgang</ce:given-name><ce:surname>Engel</ce:surname></ce:author><ce:affiliation><ce:textfn>Institute of Human Genetics, University of Göttingen, Heinrich-Düker-Weg 12, 37073, Göttingen, Germany</ce:textfn></ce:affiliation><ce:footnote id="FN1"><ce:label>1</ce:label><ce:note-para>Both authors contributed equally to this work.</ce:note-para></ce:footnote><ce:footnote id="FN2"><ce:label>2</ce:label><ce:note-para>To whom correspondence and reprint requests should be addressed. Fax: +49-551-399303. E-mail: gschlue@gwdg.de.</ce:note-para></ce:footnote></ce:author-group><ce:date-received day="22" month="10" year="2001"></ce:date-received><ce:abstract class="author"><ce:section-title>Abstract</ce:section-title><ce:abstract-sec><ce:simple-para view="all" id="simple-para.0010">During the final stages of spermatogenesis, round spermatids undergo several morphological, biochemical, and physiological modifications which result in the formation of mature spermatozoa. One of these is the nuclear condensation, achieved by the replacement of somatic-type and testis-specific histones by transition proteins and protamines leading to cessation of transcription several days before the completion of spermiogenesis. Therefore, a strict temporal and stage-specific gene expression is necessary for the correct differentiation of round spermatids into mature spermatozoa. In this study, the 5′ regulatory region of rat Tnp2 gene was investigated by primer extension analysis and transgenic mice study. Primer extension analysis revealed a transcription start site which lies 70 bp upstream of the translation start codon. By transgenic mice studies, we demonstrated that a 147-bp 5′ untranslated region corresponding to the region −74 to +73 is sufficient to confer testis- and spermatid-specific expression of rat Tnp2 gene.</ce:simple-para></ce:abstract-sec></ce:abstract><ce:keywords class="keyword"><ce:section-title>Keywords</ce:section-title><ce:keyword><ce:text>translational control</ce:text></ce:keyword><ce:keyword><ce:text>transgenic mice</ce:text></ce:keyword><ce:keyword><ce:text>RNA-binding protein</ce:text></ce:keyword><ce:keyword><ce:text>transition protein 2</ce:text></ce:keyword></ce:keywords></head></converted-article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>A 74-bp Promoter of the Tnp2 Gene Confers Testis- and Spermatid-Specific Expression in Transgenic Mice</title></titleInfo><titleInfo type="alternative" lang="en" contentType="CDATA"><title>A 74-bp Promoter of the Tnp2 Gene Confers Testis- and Spermatid-Specific Expression in Transgenic Mice</title></titleInfo><name type="personal"><namePart type="given">Özlem</namePart><namePart type="family">Topaloglu</namePart><affiliation>Institute of Human Genetics, University of Göttingen, Heinrich-Düker-Weg 12, 37073, Göttingen, Germany</affiliation><description>Both authors contributed equally to this work.</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Gregor</namePart><namePart type="family">Schlüter</namePart><affiliation>Institute of Human Genetics, University of Göttingen, Heinrich-Düker-Weg 12, 37073, Göttingen, Germany</affiliation><description>Both authors contributed equally to this work.</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Karim</namePart><namePart type="family">Nayernia</namePart><affiliation>Institute of Human Genetics, University of Göttingen, Heinrich-Düker-Weg 12, 37073, Göttingen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Wolfgang</namePart><namePart type="family">Engel</namePart><affiliation>Institute of Human Genetics, University of Göttingen, Heinrich-Düker-Weg 12, 37073, Göttingen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="Full-length article"></genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">2001</dateIssued><dateCaptured encoding="w3cdtf">2001-10-22</dateCaptured><copyrightDate encoding="w3cdtf">2001</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="en">During the final stages of spermatogenesis, round spermatids undergo several morphological, biochemical, and physiological modifications which result in the formation of mature spermatozoa. One of these is the nuclear condensation, achieved by the replacement of somatic-type and testis-specific histones by transition proteins and protamines leading to cessation of transcription several days before the completion of spermiogenesis. Therefore, a strict temporal and stage-specific gene expression is necessary for the correct differentiation of round spermatids into mature spermatozoa. In this study, the 5′ regulatory region of rat Tnp2 gene was investigated by primer extension analysis and transgenic mice study. Primer extension analysis revealed a transcription start site which lies 70 bp upstream of the translation start codon. By transgenic mice studies, we demonstrated that a 147-bp 5′ untranslated region corresponding to the region −74 to +73 is sufficient to confer testis- and spermatid-specific expression of rat Tnp2 gene.</abstract><note type="content">Section title: Regular Article</note><subject lang="en"><genre>Keywords</genre><topic>translational control</topic><topic>transgenic mice</topic><topic>RNA-binding protein</topic><topic>transition protein 2</topic></subject><relatedItem type="host"><titleInfo><title>Biochemical and Biophysical Research Communications</title></titleInfo><titleInfo type="abbreviated"><title>YBBRC</title></titleInfo><genre type="Journal">journal</genre><originInfo><dateIssued encoding="w3cdtf">20011130</dateIssued></originInfo><identifier type="ISSN">0006-291X</identifier><identifier type="PII">S0006-291X(00)X0305-1</identifier><part><date>20011130</date><detail type="volume"><number>289</number><caption>vol.</caption></detail><detail type="issue"><number>2</number><caption>no.</caption></detail><extent unit="issue pages"><start>311</start><end>641</end></extent><extent unit="pages"><start>597</start><end>601</end></extent></part></relatedItem><identifier type="istex">946E63187BADFEB705E30243ADE8B69FBD103822</identifier><identifier type="DOI">10.1006/bbrc.2001.5999</identifier><identifier type="PII">S0006-291X(01)95999-6</identifier><identifier type="ArticleID">95999</identifier><accessCondition type="use and reproduction" contentType="">© 2001Elsevier Science (USA)</accessCondition><recordInfo><recordContentSource>ELSEVIER</recordContentSource><recordOrigin>Elsevier Science (USA), ©2001</recordOrigin></recordInfo></mods></metadata><enrichments><istex:refBibTEI uri="https://api.istex.fr/document/946E63187BADFEB705E30243ADE8B69FBD103822/enrichments/refBib"><teiHeader></teiHeader><text><front></front><body></body><back><listBibl><biblStruct><analytic><title level="a" type="main">Nuclear basic proteins in spermiogenesis</title><author><persName><forename type="first">D</forename><surname>Wouters-Tyrou</surname></persName></author><author><persName><forename type="first">A</forename><surname>Martinage</surname></persName></author><author><persName><forename type="first">P</forename><surname>Chevaillier</surname></persName></author><author><persName><forename type="first">P</forename><surname>Sautiere</surname></persName></author></analytic><monogr><title level="j">Biochimie</title><imprint><biblScope unit="volume">80</biblScope><biblScope unit="page" from="117" to="128"></biblScope><date type="published" when="1998"></date></imprint></monogr></biblStruct><biblStruct><analytic><title level="a" type="main">DNA packaging in mouse spermatids. Synthesis of protamine variants and four transition proteins</title><author><persName><forename type="first">R</forename><surname>Balhorn</surname></persName></author><author><persName><forename type="first">S</forename><surname>Weston</surname></persName></author><author><persName><forename type="first">C</forename><surname>Thomas</surname></persName></author><author><persName><forename type="first">A</forename><forename type="middle">J</forename><surname>Wyrobek</surname></persName></author></analytic><monogr><title level="j">Exp. Cell Res</title><imprint><biblScope unit="volume">150</biblScope><biblScope unit="page" from="298" to="308"></biblScope><date type="published" when="1984"></date></imprint></monogr></biblStruct><biblStruct><analytic><title level="a" type="main">The mammalian sper-matozoon: Structure and temporal assembly</title><author><persName><forename type="first">A</forename><forename type="middle">R</forename><surname>Bellve</surname></persName></author><author><persName><forename type="first">O</forename><surname>Brien</surname></persName></author><author><persName><forename type="first">D</forename><forename type="middle">A</forename></persName></author></analytic><monogr><title level="m">Mechanisms and Control of Animal Fertilization</title><editor>Hartmann, J. F.</editor><meeting><address>New York</address></meeting><imprint><publisher>Academic Press</publisher><date type="published" when="1983"></date><biblScope unit="page" from="55" to="137"></biblScope></imprint></monogr></biblStruct><biblStruct><analytic><title level="a" type="main">Sperm-specific expression of angiotensin-converting enzyme (ACE) is mediated by a 91-base-pair promoter containing a CRE-like element</title><author><persName><forename type="first">T</forename><surname>Howard</surname></persName></author><author><persName><forename type="first">R</forename><surname>Balogh</surname></persName></author><author><persName><forename type="first">P</forename><surname>Overbeek</surname></persName></author><author><persName><forename type="first">K</forename><surname>Berstein</surname></persName></author></analytic><monogr><title level="j">Mol. Cell. Biol</title><imprint><biblScope unit="volume">13</biblScope><biblScope unit="page" from="18" to="27"></biblScope><date type="published" when="1993"></date></imprint></monogr></biblStruct><biblStruct><analytic><title level="a" type="main">Spermatid-specific expression of protamine 1 in transgenic mice</title><author><persName><forename type="first">J</forename><forename type="middle">J</forename><surname>Peschon</surname></persName></author><author><persName><forename type="first">R</forename><forename type="middle">R</forename><surname>Behringer</surname></persName></author><author><persName><forename type="first">R</forename><forename type="middle">L</forename><surname>Brinster</surname></persName></author><author><persName><forename type="first">R</forename><forename type="middle">D</forename><surname>Palmiter</surname></persName></author></analytic><monogr><title level="m">Proc. Natl. Acad. Sci. USA 84</title><meeting>. Natl. Acad. Sci. USA 84</meeting><imprint><date type="published" when="1987"></date><biblScope unit="page" from="5316" to="5319"></biblScope></imprint></monogr></biblStruct><biblStruct><analytic><title level="a" type="main">Expression of mouse protamine 1 genes in trans-genic mice</title><author><persName><forename type="first">J</forename><forename type="middle">J</forename><surname>Peschon</surname></persName></author><author><persName><forename type="first">R</forename><forename type="middle">R</forename><surname>Behringer</surname></persName></author><author><persName><forename type="first">R</forename><forename type="middle">D</forename><surname>Palmiter</surname></persName></author><author><persName><forename type="first">R</forename><forename type="middle">L</forename><surname>Brinster</surname></persName></author></analytic><monogr><title level="j">Ann. NY Acad. Sci</title><imprint><biblScope unit="volume">564</biblScope><biblScope unit="page" from="186" to="197"></biblScope><date type="published" when="1989"></date></imprint></monogr></biblStruct><biblStruct><analytic><title level="a" type="main">Round spermatid-specific transcription of the mouse SP-10 gene is me-diated by a 294-base pair proximal promoter</title><author><persName><forename type="first">P</forename><forename type="middle">P</forename><surname>Reddi</surname></persName></author><author><persName><forename type="first">C</forename><forename type="middle">J</forename><surname>Flickinger</surname></persName></author><author><persName><forename type="first">J</forename><forename type="middle">C</forename><surname>Herr</surname></persName></author></analytic><monogr><title level="j">Biol. Reprod</title><imprint><biblScope unit="volume">61</biblScope><biblScope unit="page" from="1256" to="1266"></biblScope><date type="published" when="1999"></date></imprint></monogr></biblStruct><biblStruct><analytic><title level="a" type="main">Analysis of the mouse protamine 1 promoter in transgenic mice</title><author><persName><forename type="first">B</forename><forename type="middle">P</forename><surname>Zambrowicz</surname></persName></author><author><persName><forename type="first">C</forename><forename type="middle">J</forename><surname>Harendza</surname></persName></author><author><persName><forename type="first">J</forename><forename type="middle">W</forename><surname>Zimmermann</surname></persName></author><author><persName><forename type="first">R</forename><forename type="middle">L</forename><surname>Brin-Ster</surname></persName></author><author><persName><forename type="first">R</forename><forename type="middle">D</forename><surname>Palmiter</surname></persName></author></analytic><monogr><title level="m">Proc. Natl. Acad. Sci. USA 90</title><meeting>. Natl. Acad. Sci. USA 90</meeting><imprint><date type="published" when="1993"></date><biblScope unit="page" from="5071" to="5"></biblScope></imprint></monogr></biblStruct><biblStruct><analytic><title level="a" type="main">Testis-specific and ubiquitous proteins bind to functionally important regions of the mouse protamine-1 promoter</title><author><persName><forename type="first">B</forename><forename type="middle">P</forename><surname>Zambrowicz</surname></persName></author><author><persName><forename type="first">R</forename><forename type="middle">D</forename><surname>Palmiter</surname></persName></author></analytic><monogr><title level="j">Biol. Reprod</title><imprint><biblScope unit="volume">50</biblScope><biblScope unit="page" from="65" to="72"></biblScope><date type="published" when="1994"></date></imprint></monogr></biblStruct><biblStruct><analytic><title level="a" type="main">Demonstration of a testis-specific trans-acting factor Tet-1 in vitro that binds to the promoter of the mouse protamine 1 gene</title><author><persName><forename type="first">T</forename><surname>Tamura</surname></persName></author><author><persName><forename type="first">Y</forename><surname>Makino</surname></persName></author><author><persName><forename type="first">K</forename><surname>Mikoshiba</surname></persName></author></analytic><monogr><title level="j">J. Biol. Chem</title><imprint><biblScope unit="volume">267</biblScope><biblScope unit="page" from="4327" to="32"></biblScope><date type="published" when="1992"></date></imprint></monogr></biblStruct><biblStruct><analytic><title level="a" type="main">Rat transition nuclear protein 2 regulatory region directs haploid expression of reporter gene in male germ cells of transgenic mice</title><author><persName><forename type="first">K</forename><surname>Nayernia</surname></persName></author><author><persName><forename type="first">D</forename><surname>Bö</surname></persName></author><author><persName><forename type="first">O</forename><forename type="middle">¨</forename><surname>Topaloglu</surname></persName></author><author><persName><forename type="first">G</forename><surname>Schlü Ter</surname></persName></author><author><persName><forename type="first">W</forename><surname>Engel</surname></persName></author></analytic><monogr><title level="j">Mol. Reprod. Dev</title><imprint><biblScope unit="volume">58</biblScope><biblScope unit="page" from="368" to="375"></biblScope><date type="published" when="2001"></date></imprint></monogr></biblStruct><biblStruct><analytic><title level="a" type="main">CAT constructions with mul-tiple unique restriction sites for the functional analysis of eu-karyotic promoters and regulatory elements</title><author><persName><forename type="first">B</forename><surname>Luckow</surname></persName></author><author><persName><forename type="first">G</forename><surname>Schutz</surname></persName></author></analytic><monogr><title level="j">Nucleic Acids Res</title><imprint><biblScope unit="volume">13</biblScope><biblScope unit="page">5490</biblScope><date type="published" when="1987"></date></imprint></monogr></biblStruct><biblStruct><monogr><title level="m" type="main">Manipulating the Mouse Embryo: A Laboratory Manual</title><author><persName><forename type="first">B</forename><surname>Hogan</surname></persName></author><author><persName><forename type="first">F</forename><surname>Constantini</surname></persName></author><author><persName><forename type="first">E</forename><surname>Lacy</surname></persName></author><imprint><date type="published" when="1986"></date><biblScope unit="page" from="151" to="206"></biblScope><pubPlace>NY</pubPlace></imprint></monogr></biblStruct><biblStruct><analytic><title level="a" type="main">Functional and molecular characterization of the transcriptional regulatory region of the proacrosin gene</title><author><persName><forename type="first">K</forename><surname>Nayernia</surname></persName></author><author><persName><forename type="first">S</forename><surname>Nieter</surname></persName></author><author><persName><forename type="first">H</forename><surname>Kremling</surname></persName></author><author><persName><forename type="first">H</forename><surname>Oberwinkler</surname></persName></author><author><persName><forename type="first">W</forename><surname>Engel</surname></persName></author></analytic><monogr><title level="j">J. Biol. Chem</title><imprint><biblScope unit="volume">51</biblScope><biblScope unit="page" from="32181" to="32186"></biblScope><date type="published" when="1994"></date></imprint></monogr></biblStruct><biblStruct><analytic><title level="a" type="main">Demonstration of trans-acting factors binding to the promoter region of the testis-specific rat protamine P1 gene</title><author><persName><forename type="first">R</forename><surname>Queralt</surname></persName></author><author><persName><forename type="first">R</forename><surname>Oliva</surname></persName></author></analytic><monogr><title level="j">Biochem. Biophys. Res. Commun</title><imprint><biblScope unit="volume">208</biblScope><biblScope unit="page" from="802" to="812"></biblScope><date type="published" when="1995"></date></imprint></monogr></biblStruct><biblStruct><analytic><title level="a" type="main">Identification of conserved potential regulatory sequences of the protamine-encoding P1 genes from ten different mammals</title><author><persName><forename type="first">R</forename><surname>Queralt</surname></persName></author><author><persName><forename type="first">R</forename><surname>Oliva</surname></persName></author></analytic><monogr><title level="j">Gene</title><imprint><biblScope unit="volume">15</biblScope><biblScope unit="page" from="197" to="204"></biblScope><date type="published" when="1994"></date></imprint></monogr></biblStruct><biblStruct><analytic><title level="a" type="main">Iden-tification of a functional cyclic adenosine 3Ј,5Ј-monophosphate response element in the 5Ј-flanking region of the gene for tran-sition protein 1 (TP1), a basic chromosomal protein of mamma-lian spermatids</title><author><persName><forename type="first">M</forename><forename type="middle">K</forename><surname>Kistler</surname></persName></author><author><persName><forename type="first">P</forename><surname>Sassone-Corsi</surname></persName></author><author><persName><forename type="first">W</forename><forename type="middle">S</forename><surname>Kistler</surname></persName></author></analytic><monogr><title level="j">Biol. Reprod</title><imprint><biblScope unit="volume">51</biblScope><biblScope unit="page" from="1322" to="1329"></biblScope><date type="published" when="1994"></date></imprint></monogr></biblStruct><biblStruct><analytic><title level="a" type="main">Protein binding regions in the mouse and rat protamine-2 genes</title><author><persName><forename type="first">P</forename><forename type="middle">A</forename><surname>Johnson</surname></persName></author><author><persName><forename type="first">D</forename><surname>Bunick</surname></persName></author><author><persName><forename type="first">N</forename><forename type="middle">B</forename><surname>Hecht</surname></persName></author></analytic><monogr><title level="j">Biol. Reprod</title><imprint><biblScope unit="volume">44</biblScope><biblScope unit="page" from="127" to="134"></biblScope><date type="published" when="1991"></date></imprint></monogr></biblStruct><biblStruct><analytic><title level="a" type="main">Characterization of the promoter region of the rat testis-specific histone H1t gene</title><author><persName><forename type="first">S</forename><forename type="middle">E</forename><surname>Clare</surname></persName></author><author><persName><forename type="first">W</forename><forename type="middle">R</forename><surname>Hatfield</surname></persName></author><author><persName><forename type="first">D</forename><forename type="middle">A</forename><surname>Fantz</surname></persName></author><author><persName><forename type="first">W</forename><forename type="middle">S</forename><surname>Kistler</surname></persName></author><author><persName><forename type="first">M</forename><forename type="middle">K</forename><surname>Kistler</surname></persName></author></analytic><monogr><title level="j">Biol. Reprod</title><imprint><biblScope unit="volume">56</biblScope><biblScope unit="page" from="73" to="82"></biblScope><date type="published" when="1997"></date></imprint></monogr></biblStruct><biblStruct><analytic></analytic><monogr><title level="j">BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS</title><imprint><biblScope unit="volume">289</biblScope><biblScope unit="issue">2</biblScope><date type="published" when="2001"></date></imprint></monogr></biblStruct></listBibl></back></text></istex:refBibTEI></enrichments><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Musique/explor/SchutzV1/Data/Main/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000386 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Corpus/biblio.hfd -nk 000386 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Musique
|area= SchutzV1
|flux= Main
|étape= Corpus
|type= RBID
|clé= ISTEX:946E63187BADFEB705E30243ADE8B69FBD103822
|texte= A 74-bp Promoter of the Tnp2 Gene Confers Testis- and Spermatid-Specific Expression in Transgenic Mice
}}
| This area was generated with Dilib version V0.6.38. |  |