Ischemia-modified albumin levels predict long-term outcome in patients with acute myocardial infarction. The French Nationwide OPERA study.
Identifieur interne : 000363 ( PubMed/Curation ); précédent : 000362; suivant : 000364Ischemia-modified albumin levels predict long-term outcome in patients with acute myocardial infarction. The French Nationwide OPERA study.
Auteurs : Eric Van Belle [France] ; Jean Dallongeville ; Eric Vicaut ; Alexia Degrandsart ; Cathrine Baulac ; Gilles MontalescotSource :
- American heart journal ; 2010.
Descripteurs français
- Wicri :
- geographic : France.
English descriptors
- KwdEn :
- MESH :
- chemical , analysis : Albumins.
- geographic : France.
- blood : Myocardial Infarction.
- therapy : Myocardial Infarction.
- Aged, Female, Humans, Male, Middle Aged, Predictive Value of Tests, Time Factors, Treatment Outcome.
Abstract
Little is known about the capacity of ischemia-modified albumin (IMA) plasma concentration to predict long-term cardiac outcome in patients with established acute myocardial infarction (AMI). Because IMA is a marker of ischemia rather than myocardial cell damage, we hypothesized that IMA plasma levels could provide additional prognostic value to classic clinical and biological risk markers in patients with AMI. Therefore, we investigated the predictive value of plasma IMA in patients with AMI enrolled in the French Nationwide OPERA study.
DOI: 10.1016/j.ahj.2009.12.026
PubMed: 20362714
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Ischemia-modified albumin levels predict long-term outcome in patients with acute myocardial infarction. The French Nationwide OPERA study.</title><author><name sortKey="Van Belle, Eric" sort="Van Belle, Eric" uniqKey="Van Belle E" first="Eric" last="Van Belle">Eric Van Belle</name><affiliation wicri:level="1"><nlm:affiliation>Hopital Cardiologique and EA2693, Lille, France. ericvanbelle@aol.com</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Hopital Cardiologique and EA2693, Lille</wicri:regionArea></affiliation></author><author><name sortKey="Dallongeville, Jean" sort="Dallongeville, Jean" uniqKey="Dallongeville J" first="Jean" last="Dallongeville">Jean Dallongeville</name></author><author><name sortKey="Vicaut, Eric" sort="Vicaut, Eric" uniqKey="Vicaut E" first="Eric" last="Vicaut">Eric Vicaut</name></author><author><name sortKey="Degrandsart, Alexia" sort="Degrandsart, Alexia" uniqKey="Degrandsart A" first="Alexia" last="Degrandsart">Alexia Degrandsart</name></author><author><name sortKey="Baulac, Cathrine" sort="Baulac, Cathrine" uniqKey="Baulac C" first="Cathrine" last="Baulac">Cathrine Baulac</name></author><author><name sortKey="Montalescot, Gilles" sort="Montalescot, Gilles" uniqKey="Montalescot G" first="Gilles" last="Montalescot">Gilles Montalescot</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2010">2010</date><idno type="doi">10.1016/j.ahj.2009.12.026</idno><idno type="RBID">pubmed:20362714</idno><idno type="pmid">20362714</idno><idno type="wicri:Area/PubMed/Corpus">000363</idno><idno type="wicri:Area/PubMed/Curation">000363</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Ischemia-modified albumin levels predict long-term outcome in patients with acute myocardial infarction. The French Nationwide OPERA study.</title><author><name sortKey="Van Belle, Eric" sort="Van Belle, Eric" uniqKey="Van Belle E" first="Eric" last="Van Belle">Eric Van Belle</name><affiliation wicri:level="1"><nlm:affiliation>Hopital Cardiologique and EA2693, Lille, France. ericvanbelle@aol.com</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Hopital Cardiologique and EA2693, Lille</wicri:regionArea></affiliation></author><author><name sortKey="Dallongeville, Jean" sort="Dallongeville, Jean" uniqKey="Dallongeville J" first="Jean" last="Dallongeville">Jean Dallongeville</name></author><author><name sortKey="Vicaut, Eric" sort="Vicaut, Eric" uniqKey="Vicaut E" first="Eric" last="Vicaut">Eric Vicaut</name></author><author><name sortKey="Degrandsart, Alexia" sort="Degrandsart, Alexia" uniqKey="Degrandsart A" first="Alexia" last="Degrandsart">Alexia Degrandsart</name></author><author><name sortKey="Baulac, Cathrine" sort="Baulac, Cathrine" uniqKey="Baulac C" first="Cathrine" last="Baulac">Cathrine Baulac</name></author><author><name sortKey="Montalescot, Gilles" sort="Montalescot, Gilles" uniqKey="Montalescot G" first="Gilles" last="Montalescot">Gilles Montalescot</name></author></analytic><series><title level="j">American heart journal</title><idno type="e-ISSN">1097-6744</idno><imprint><date when="2010" type="published">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Albumins (analysis)</term><term>Female</term><term>France</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Myocardial Infarction (blood)</term><term>Myocardial Infarction (therapy)</term><term>Predictive Value of Tests</term><term>Time Factors</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Albumins</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>France</term></keywords><keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Myocardial Infarction</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Myocardial Infarction</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Predictive Value of Tests</term><term>Time Factors</term><term>Treatment Outcome</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>France</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Little is known about the capacity of ischemia-modified albumin (IMA) plasma concentration to predict long-term cardiac outcome in patients with established acute myocardial infarction (AMI). Because IMA is a marker of ischemia rather than myocardial cell damage, we hypothesized that IMA plasma levels could provide additional prognostic value to classic clinical and biological risk markers in patients with AMI. Therefore, we investigated the predictive value of plasma IMA in patients with AMI enrolled in the French Nationwide OPERA study.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">20362714</PMID><DateCreated><Year>2010</Year><Month>04</Month><Day>05</Day></DateCreated><DateCompleted><Year>2010</Year><Month>05</Month><Day>13</Day></DateCompleted><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1097-6744</ISSN><JournalIssue CitedMedium="Internet"><Volume>159</Volume><Issue>4</Issue><PubDate><Year>2010</Year><Month>Apr</Month></PubDate></JournalIssue><Title>American heart journal</Title><ISOAbbreviation>Am. Heart J.</ISOAbbreviation></Journal><ArticleTitle>Ischemia-modified albumin levels predict long-term outcome in patients with acute myocardial infarction. The French Nationwide OPERA study.</ArticleTitle><Pagination><MedlinePgn>570-6</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.ahj.2009.12.026</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Little is known about the capacity of ischemia-modified albumin (IMA) plasma concentration to predict long-term cardiac outcome in patients with established acute myocardial infarction (AMI). Because IMA is a marker of ischemia rather than myocardial cell damage, we hypothesized that IMA plasma levels could provide additional prognostic value to classic clinical and biological risk markers in patients with AMI. Therefore, we investigated the predictive value of plasma IMA in patients with AMI enrolled in the French Nationwide OPERA study.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Plasma concentrations of IMA and other cardiac biomarkers (troponin, C-reactive protein, B-type natriuretic peptide) were measured within 24 hours of hospital admission in 471 patients hospitalized with an AMI (defined using European Society of Cardiology/American College of Cardiology criteria). Patients' characteristics, cardiovascular risk factors and treatments, and clinical outcomes were recorded. Univariate and multivariable predictors of cardiac outcome in-hospital and at 1 year were identified.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">The primary composite end point (death, resuscitated cardiac arrest, recurrent myocardial infarction or ischemia, heart failure, stroke) occurred in 75 (15.6%) patients in-hospital and in 144 (30.6%) at 1 year: 40% of patients in the highest IMA quartile (>104 IU/mL) reached the end point compared with 20% in the lowest (<83 IU/mL) by 1 year. Multivariable logistic regression analysis identified 4 independent predictors of composite end point at 1 year: plasma concentrations of IMA (P = .01), brain natriuretic peptide (P = .001), heart failure (P = .005), and age (P = .003).</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">In patients with AMI, IMA measured within 24 hours is a strong and independent predictor of cardiac outcome at 1 year and may help identify those requiring more aggressive medical management.</AbstractText><CopyrightInformation>Copyright 2010 Mosby, Inc. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Van Belle</LastName><ForeName>Eric</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Hopital Cardiologique and EA2693, Lille, France. ericvanbelle@aol.com</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dallongeville</LastName><ForeName>Jean</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Vicaut</LastName><ForeName>Eric</ForeName><Initials>E</Initials></Author><Author ValidYN="Y"><LastName>Degrandsart</LastName><ForeName>Alexia</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Baulac</LastName><ForeName>Cathrine</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Montalescot</LastName><ForeName>Gilles</ForeName><Initials>G</Initials></Author><Author ValidYN="Y"><CollectiveName>OPERA Investigators</CollectiveName></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Am Heart J</MedlineTA><NlmUniqueID>0370465</NlmUniqueID><ISSNLinking>0002-8703</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000418">Albumins</NameOfSubstance></Chemical></ChemicalList><CitationSubset>AIM</CitationSubset><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000418">Albumins</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000032">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" Type="Geographic" UI="D005602">France</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D009203">Myocardial Infarction</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000097">blood</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000628">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D011237">Predictive Value of Tests</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D013997">Time Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D016896">Treatment Outcome</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2009</Year><Month>8</Month><Day>6</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2009</Year><Month>12</Month><Day>2</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2010</Year><Month>4</Month><Day>6</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2010</Year><Month>4</Month><Day>7</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2010</Year><Month>5</Month><Day>14</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pii">S0002-8703(10)00065-7</ArticleId><ArticleId IdType="doi">10.1016/j.ahj.2009.12.026</ArticleId><ArticleId IdType="pubmed">20362714</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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