The potential role of acid suppression in functional dyspepsia: the BOND, OPERA, PILOT, and ENCORE studies.
Identifieur interne : 000621 ( PubMed/Corpus ); précédent : 000620; suivant : 000622The potential role of acid suppression in functional dyspepsia: the BOND, OPERA, PILOT, and ENCORE studies.
Auteurs : N J Talley ; K. LauritsenSource :
- Gut [ 0017-5749 ] ; 2002.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Anti-Ulcer Agents, Omeprazole.
- drug therapy : Dyspepsia.
- Adult, Double-Blind Method, Female, Humans, Male, Randomized Controlled Trials as Topic, Treatment Outcome.
Abstract
Dyspepsia is a common condition in the general population but data are lacking on the benefits of effective acid inhibition with proton pump inhibitors in functional dyspepsia. The results of the large, randomised, double blind clinical trials, BOND and OPERA, the Scandinavian PILOT study, and a follow up study, ENCORE, are reviewed. BOND, OPERA, and PILOT aimed to address the question of whether effective acid inhibition with the proton pump inhibitor omeprazole relieves symptoms in patients with functional dyspepsia. ENCORE followed on from this, addressing the consequences of relieving symptoms in patients with functional dyspepsia once they are off therapy.
PubMed: 11953346
Links to Exploration step
pubmed:11953346Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The potential role of acid suppression in functional dyspepsia: the BOND, OPERA, PILOT, and ENCORE studies.</title><author><name sortKey="Talley, N J" sort="Talley, N J" uniqKey="Talley N" first="N J" last="Talley">N J Talley</name><affiliation><nlm:affiliation>Department of Medicine, University of Sydney, Nepean Hospital, Penrith 2751, Australia. ntalley@blackburn.med.su.oz.au</nlm:affiliation></affiliation></author><author><name sortKey="Lauritsen, K" sort="Lauritsen, K" uniqKey="Lauritsen K" first="K" last="Lauritsen">K. Lauritsen</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2002">2002</date><idno type="RBID">pubmed:11953346</idno><idno type="pmid">11953346</idno><idno type="wicri:Area/PubMed/Corpus">000621</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">The potential role of acid suppression in functional dyspepsia: the BOND, OPERA, PILOT, and ENCORE studies.</title><author><name sortKey="Talley, N J" sort="Talley, N J" uniqKey="Talley N" first="N J" last="Talley">N J Talley</name><affiliation><nlm:affiliation>Department of Medicine, University of Sydney, Nepean Hospital, Penrith 2751, Australia. ntalley@blackburn.med.su.oz.au</nlm:affiliation></affiliation></author><author><name sortKey="Lauritsen, K" sort="Lauritsen, K" uniqKey="Lauritsen K" first="K" last="Lauritsen">K. Lauritsen</name></author></analytic><series><title level="j">Gut</title><idno type="ISSN">0017-5749</idno><imprint><date when="2002" type="published">2002</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Anti-Ulcer Agents (therapeutic use)</term><term>Double-Blind Method</term><term>Dyspepsia (drug therapy)</term><term>Female</term><term>Humans</term><term>Male</term><term>Omeprazole (therapeutic use)</term><term>Randomized Controlled Trials as Topic</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anti-Ulcer Agents</term><term>Omeprazole</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Dyspepsia</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Double-Blind Method</term><term>Female</term><term>Humans</term><term>Male</term><term>Randomized Controlled Trials as Topic</term><term>Treatment Outcome</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Dyspepsia is a common condition in the general population but data are lacking on the benefits of effective acid inhibition with proton pump inhibitors in functional dyspepsia. The results of the large, randomised, double blind clinical trials, BOND and OPERA, the Scandinavian PILOT study, and a follow up study, ENCORE, are reviewed. BOND, OPERA, and PILOT aimed to address the question of whether effective acid inhibition with the proton pump inhibitor omeprazole relieves symptoms in patients with functional dyspepsia. ENCORE followed on from this, addressing the consequences of relieving symptoms in patients with functional dyspepsia once they are off therapy.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">11953346</PMID><DateCreated><Year>2002</Year><Month>04</Month><Day>15</Day></DateCreated><DateCompleted><Year>2002</Year><Month>06</Month><Day>04</Day></DateCompleted><DateRevised><Year>2014</Year><Month>06</Month><Day>13</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0017-5749</ISSN><JournalIssue CitedMedium="Print"><Volume>50 Suppl 4</Volume><PubDate><Year>2002</Year><Month>May</Month></PubDate></JournalIssue><Title>Gut</Title><ISOAbbreviation>Gut</ISOAbbreviation></Journal><ArticleTitle>The potential role of acid suppression in functional dyspepsia: the BOND, OPERA, PILOT, and ENCORE studies.</ArticleTitle><Pagination><MedlinePgn>iv36-41</MedlinePgn></Pagination><Abstract><AbstractText>Dyspepsia is a common condition in the general population but data are lacking on the benefits of effective acid inhibition with proton pump inhibitors in functional dyspepsia. The results of the large, randomised, double blind clinical trials, BOND and OPERA, the Scandinavian PILOT study, and a follow up study, ENCORE, are reviewed. BOND, OPERA, and PILOT aimed to address the question of whether effective acid inhibition with the proton pump inhibitor omeprazole relieves symptoms in patients with functional dyspepsia. ENCORE followed on from this, addressing the consequences of relieving symptoms in patients with functional dyspepsia once they are off therapy.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Talley</LastName><ForeName>N J</ForeName><Initials>NJ</Initials><AffiliationInfo><Affiliation>Department of Medicine, University of Sydney, Nepean Hospital, Penrith 2751, Australia. ntalley@blackburn.med.su.oz.au</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lauritsen</LastName><ForeName>K</ForeName><Initials>K</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D017418">Meta-Analysis</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Gut</MedlineTA><NlmUniqueID>2985108R</NlmUniqueID><ISSNLinking>0017-5749</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000897">Anti-Ulcer Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>KG60484QX9</RegistryNumber><NameOfSubstance UI="D009853">Omeprazole</NameOfSubstance></Chemical></ChemicalList><CitationSubset>AIM</CitationSubset><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Gut. 2000 Oct;47(4):473-80</RefSource><PMID Version="1">10986206</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Gut. 1999 Jul;45 Suppl 1:I32-5</RefSource><PMID Version="1">10457034</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Clin Gastroenterol. 1987 Jun;9(3):303-9</RefSource><PMID Version="1">3611684</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Ann Intern Med. 1988 Jun;108(6):865-79</RefSource><PMID Version="1">3285748</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Dig Dis Sci. 1989 Feb;34(2):246-50</RefSource><PMID Version="1">2914546</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Scand J Gastroenterol. 1989 Mar;24(2):145-50</RefSource><PMID Version="1">2928729</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Gastroenterology. 1989 Aug;97(2):376-83</RefSource><PMID Version="1">2744356</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Gastroenterology. 1991 Jul;101(1):3-6</RefSource><PMID Version="1">2044924</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Scand J Gastroenterol Suppl. 1991;182:47-60</RefSource><PMID Version="1">1896830</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Gastroenterology. 1992 Apr;102(4 Pt 1):1259-68</RefSource><PMID Version="1">1551533</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Gut. 1995 Apr;36(4):534-8</RefSource><PMID Version="1">7737559</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Aliment Pharmacol Ther. 1995 Apr;9(2):107-15</RefSource><PMID Version="1">7605850</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Am J Gastroenterol. 1996 Apr;91(4):660-73</RefSource><PMID Version="1">8677926</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Aliment Pharmacol Ther. 1997 Jun;11(3):541-6</RefSource><PMID Version="1">9218080</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Aliment Pharmacol Ther. 1998 Mar;12(3):263-71</RefSource><PMID Version="1">9570261</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Aliment Pharmacol Ther. 1998 Feb;12(2):147-57</RefSource><PMID Version="1">9692689</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Aliment Pharmacol Ther. 1998 Nov;12(11):1055-65</RefSource><PMID Version="1">9845395</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Gastroenterology. 1999 Mar;116(3):515-20</RefSource><PMID Version="1">10029608</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Scand J Gastroenterol. 1999 Jun;34(6):566-74</RefSource><PMID Version="1">10440605</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Scand J Gastroenterol Suppl. 1985;109:41-7</RefSource><PMID Version="1">3860922</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000328">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000897">Anti-Ulcer Agents</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000627">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D004311">Double-Blind Method</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D004415">Dyspepsia</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000188">drug therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D009853">Omeprazole</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000627">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D016032">Randomized Controlled Trials as Topic</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D016896">Treatment Outcome</DescriptorName></MeshHeading></MeshHeadingList><OtherID Source="NLM">PMC1867693</OtherID></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2002</Year><Month>4</Month><Day>16</Day><Hour>10</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2002</Year><Month>6</Month><Day>5</Day><Hour>10</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2002</Year><Month>4</Month><Day>16</Day><Hour>10</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">11953346</ArticleId><ArticleId IdType="pmc">PMC1867693</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Musique/explor/OperaV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000621 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 000621 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Musique
|area= OperaV1
|flux= PubMed
|étape= Corpus
|type= RBID
|clé= pubmed:11953346
|texte= The potential role of acid suppression in functional dyspepsia: the BOND, OPERA, PILOT, and ENCORE studies.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:11953346" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a OperaV1
| This area was generated with Dilib version V0.6.21. |  |