STEMI and NSTEMI: are they so different? 1 year outcomes in acute myocardial infarction as defined by the ESC/ACC definition (the OPERA registry).
Identifieur interne : 000464 ( PubMed/Corpus ); précédent : 000463; suivant : 000465STEMI and NSTEMI: are they so different? 1 year outcomes in acute myocardial infarction as defined by the ESC/ACC definition (the OPERA registry).
Auteurs : Gilles Montalescot ; Jean Dallongeville ; Eric Van Belle ; Stephanie Rouanet ; Cathrine Baulac ; Alexia Degrandsart ; Eric VicautSource :
- European heart journal [ 0195-668X ] ; 2007.
English descriptors
- KwdEn :
- Age Factors, Aged, Aged, 80 and over, Angioplasty, Balloon, Coronary, Coronary Artery Bypass, Electrocardiography, Female, Fibrinolytic Agents (therapeutic use), France (epidemiology), Heart Conduction System, Hospital Mortality, Humans, Male, Middle Aged, Myocardial Infarction (diagnosis), Myocardial Infarction (mortality), Myocardial Infarction (therapy), Myocardial Reperfusion, Patient Readmission (statistics & numerical data), Prospective Studies, Registries, Risk Factors, Severity of Illness Index, Time Factors.
- MESH :
- chemical , therapeutic use : Fibrinolytic Agents.
- geographic , epidemiology : France.
- diagnosis : Myocardial Infarction.
- mortality : Myocardial Infarction.
- statistics & numerical data : Patient Readmission.
- therapy : Myocardial Infarction.
- Age Factors, Aged, Aged, 80 and over, Angioplasty, Balloon, Coronary, Coronary Artery Bypass, Electrocardiography, Female, Heart Conduction System, Hospital Mortality, Humans, Male, Middle Aged, Myocardial Reperfusion, Prospective Studies, Registries, Risk Factors, Severity of Illness Index, Time Factors.
Abstract
The ESC/ACC redefined myocardial infarction as any amount of necrosis caused by ischaemia. The aim of this study was to describe the management and outcomes using 'real-world' data taking the new definition of acute myocardial infarction into account.
DOI: 10.1093/eurheartj/ehm031
PubMed: 17412730
Links to Exploration step
pubmed:17412730Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">STEMI and NSTEMI: are they so different? 1 year outcomes in acute myocardial infarction as defined by the ESC/ACC definition (the OPERA registry).</title><author><name sortKey="Montalescot, Gilles" sort="Montalescot, Gilles" uniqKey="Montalescot G" first="Gilles" last="Montalescot">Gilles Montalescot</name><affiliation><nlm:affiliation>Institut de Cardiologie and INSERM U856, Pitié-Salpétrière University Hospital, AP-HP, 47 Boulevard de l'Hôpital, Paris 75013, France. gilles.montalescot@psl.aphp.fr</nlm:affiliation></affiliation></author><author><name sortKey="Dallongeville, Jean" sort="Dallongeville, Jean" uniqKey="Dallongeville J" first="Jean" last="Dallongeville">Jean Dallongeville</name></author><author><name sortKey="Van Belle, Eric" sort="Van Belle, Eric" uniqKey="Van Belle E" first="Eric" last="Van Belle">Eric Van Belle</name></author><author><name sortKey="Rouanet, Stephanie" sort="Rouanet, Stephanie" uniqKey="Rouanet S" first="Stephanie" last="Rouanet">Stephanie Rouanet</name></author><author><name sortKey="Baulac, Cathrine" sort="Baulac, Cathrine" uniqKey="Baulac C" first="Cathrine" last="Baulac">Cathrine Baulac</name></author><author><name sortKey="Degrandsart, Alexia" sort="Degrandsart, Alexia" uniqKey="Degrandsart A" first="Alexia" last="Degrandsart">Alexia Degrandsart</name></author><author><name sortKey="Vicaut, Eric" sort="Vicaut, Eric" uniqKey="Vicaut E" first="Eric" last="Vicaut">Eric Vicaut</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2007">2007</date><idno type="doi">10.1093/eurheartj/ehm031</idno><idno type="RBID">pubmed:17412730</idno><idno type="pmid">17412730</idno><idno type="wicri:Area/PubMed/Corpus">000464</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">STEMI and NSTEMI: are they so different? 1 year outcomes in acute myocardial infarction as defined by the ESC/ACC definition (the OPERA registry).</title><author><name sortKey="Montalescot, Gilles" sort="Montalescot, Gilles" uniqKey="Montalescot G" first="Gilles" last="Montalescot">Gilles Montalescot</name><affiliation><nlm:affiliation>Institut de Cardiologie and INSERM U856, Pitié-Salpétrière University Hospital, AP-HP, 47 Boulevard de l'Hôpital, Paris 75013, France. gilles.montalescot@psl.aphp.fr</nlm:affiliation></affiliation></author><author><name sortKey="Dallongeville, Jean" sort="Dallongeville, Jean" uniqKey="Dallongeville J" first="Jean" last="Dallongeville">Jean Dallongeville</name></author><author><name sortKey="Van Belle, Eric" sort="Van Belle, Eric" uniqKey="Van Belle E" first="Eric" last="Van Belle">Eric Van Belle</name></author><author><name sortKey="Rouanet, Stephanie" sort="Rouanet, Stephanie" uniqKey="Rouanet S" first="Stephanie" last="Rouanet">Stephanie Rouanet</name></author><author><name sortKey="Baulac, Cathrine" sort="Baulac, Cathrine" uniqKey="Baulac C" first="Cathrine" last="Baulac">Cathrine Baulac</name></author><author><name sortKey="Degrandsart, Alexia" sort="Degrandsart, Alexia" uniqKey="Degrandsart A" first="Alexia" last="Degrandsart">Alexia Degrandsart</name></author><author><name sortKey="Vicaut, Eric" sort="Vicaut, Eric" uniqKey="Vicaut E" first="Eric" last="Vicaut">Eric Vicaut</name></author></analytic><series><title level="j">European heart journal</title><idno type="ISSN">0195-668X</idno><imprint><date when="2007" type="published">2007</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Age Factors</term><term>Aged</term><term>Aged, 80 and over</term><term>Angioplasty, Balloon, Coronary</term><term>Coronary Artery Bypass</term><term>Electrocardiography</term><term>Female</term><term>Fibrinolytic Agents (therapeutic use)</term><term>France (epidemiology)</term><term>Heart Conduction System</term><term>Hospital Mortality</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Myocardial Infarction (diagnosis)</term><term>Myocardial Infarction (mortality)</term><term>Myocardial Infarction (therapy)</term><term>Myocardial Reperfusion</term><term>Patient Readmission (statistics & numerical data)</term><term>Prospective Studies</term><term>Registries</term><term>Risk Factors</term><term>Severity of Illness Index</term><term>Time Factors</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Fibrinolytic Agents</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>France</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Myocardial Infarction</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Myocardial Infarction</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Patient Readmission</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Myocardial Infarction</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Age Factors</term><term>Aged</term><term>Aged, 80 and over</term><term>Angioplasty, Balloon, Coronary</term><term>Coronary Artery Bypass</term><term>Electrocardiography</term><term>Female</term><term>Heart Conduction System</term><term>Hospital Mortality</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Myocardial Reperfusion</term><term>Prospective Studies</term><term>Registries</term><term>Risk Factors</term><term>Severity of Illness Index</term><term>Time Factors</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The ESC/ACC redefined myocardial infarction as any amount of necrosis caused by ischaemia. The aim of this study was to describe the management and outcomes using 'real-world' data taking the new definition of acute myocardial infarction into account.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">17412730</PMID><DateCreated><Year>2007</Year><Month>06</Month><Day>21</Day></DateCreated><DateCompleted><Year>2007</Year><Month>12</Month><Day>20</Day></DateCompleted><DateRevised><Year>2013</Year><Month>02</Month><Day>07</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Print">0195-668X</ISSN><JournalIssue CitedMedium="Print"><Volume>28</Volume><Issue>12</Issue><PubDate><Year>2007</Year><Month>Jun</Month></PubDate></JournalIssue><Title>European heart journal</Title><ISOAbbreviation>Eur. Heart J.</ISOAbbreviation></Journal><ArticleTitle>STEMI and NSTEMI: are they so different? 1 year outcomes in acute myocardial infarction as defined by the ESC/ACC definition (the OPERA registry).</ArticleTitle><Pagination><MedlinePgn>1409-17</MedlinePgn></Pagination><Abstract><AbstractText Label="AIMS" NlmCategory="OBJECTIVE">The ESC/ACC redefined myocardial infarction as any amount of necrosis caused by ischaemia. The aim of this study was to describe the management and outcomes using 'real-world' data taking the new definition of acute myocardial infarction into account.</AbstractText><AbstractText Label="METHODS AND RESULTS" NlmCategory="RESULTS">A total of 2,151 consecutive patients (76.0% men) with a myocardial infarction were enrolled at 56 centres in France. The median delay to presentation was shorter in patients with ST-segment elevation myocardial infarction (STEMI) vs. non-STEMI (NSTEMI) (4 vs. 7 h, P < 0.0001). STEMI patients were more likely to receive fibrinolysis (28.9 vs. 0.7%, P < 0.0001) or undergo PCI (71.0 vs. 51.6%, P < 0.0001) but less likely to have bypass surgery (3.1 vs. 4.9%, P < 0.05). At discharge, patients with STEMI received more aggressive secondary prevention therapies than those with NSTEMI, which was not supported by differences in disease severity. A total of 1878 patients were followed-up for 1 year: 36.7% of STEMI and 41.5% of NSTEMI patients were rehospitalized (P = 0.05); 16% in both groups were revascularized. In-hospital mortality was similar (4.6 vs. 4.3%), and 1-year mortality was 9.0% in STEMI patients and 11.6% in NSTEMI patients (Log-Rank P = 0.09). Independent correlates of in-hospital mortality were untreated dyslipidaemia, advanced age, diabetes, and low blood pressure. The strongest predictors of 1-year mortality were heart failure and age. Similar predictors were found in STEMI and NSTEMI subgroups.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Despite different management, patients with STEMI and NSTEMI have similar prognoses and independent correlates of outcome. These findings support the new definition of myocardial infarction.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Montalescot</LastName><ForeName>Gilles</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Institut de Cardiologie and INSERM U856, Pitié-Salpétrière University Hospital, AP-HP, 47 Boulevard de l'Hôpital, Paris 75013, France. gilles.montalescot@psl.aphp.fr</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dallongeville</LastName><ForeName>Jean</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Van Belle</LastName><ForeName>Eric</ForeName><Initials>E</Initials></Author><Author ValidYN="Y"><LastName>Rouanet</LastName><ForeName>Stephanie</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Baulac</LastName><ForeName>Cathrine</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Degrandsart</LastName><ForeName>Alexia</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Vicaut</LastName><ForeName>Eric</ForeName><Initials>E</Initials></Author><Author ValidYN="Y"><CollectiveName>OPERA Investigators</CollectiveName></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2007</Year><Month>04</Month><Day>05</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Eur Heart J</MedlineTA><NlmUniqueID>8006263</NlmUniqueID><ISSNLinking>0195-668X</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D005343">Fibrinolytic Agents</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>Eur Heart J. 2007 Nov;28(21):2685; author reply 2685</RefSource><PMID Version="1">17827201</PMID></CommentsCorrections><CommentsCorrections RefType="CommentIn"><RefSource>Eur Heart J. 2007 Jun;28(12):1403-4</RefSource><PMID Version="1">17526505</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000367">Age Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000369">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D015906">Angioplasty, Balloon, Coronary</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D001026">Coronary Artery Bypass</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D004562">Electrocardiography</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005343">Fibrinolytic Agents</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000627">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" Type="Geographic" UI="D005602">France</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000453">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006329">Heart Conduction System</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D017052">Hospital Mortality</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D009203">Myocardial Infarction</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000175">diagnosis</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000401">mortality</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000628">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D015425">Myocardial Reperfusion</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D010359">Patient Readmission</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000706">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D011446">Prospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D012042">Registries</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D012307">Risk Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D012720">Severity of Illness Index</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D013997">Time Factors</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="aheadofprint"><Year>2007</Year><Month>4</Month><Day>5</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2007</Year><Month>4</Month><Day>7</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2007</Year><Month>12</Month><Day>21</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2007</Year><Month>4</Month><Day>7</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pii">ehm031</ArticleId><ArticleId IdType="doi">10.1093/eurheartj/ehm031</ArticleId><ArticleId IdType="pubmed">17412730</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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