Improved Treatment Satisfaction and Self-reported Health Status after Introduction of Basal-Supported Oral Therapy Using Insulin Glargine in Patients with Type 2 Diabetes: Sub-Analysis of ALOHA2 Study.
Identifieur interne : 000077 ( PubMed/Corpus ); précédent : 000076; suivant : 000078Improved Treatment Satisfaction and Self-reported Health Status after Introduction of Basal-Supported Oral Therapy Using Insulin Glargine in Patients with Type 2 Diabetes: Sub-Analysis of ALOHA2 Study.
Auteurs : Shoko Tsukube ; Yukio Ikeda ; Takashi Kadowaki ; Masato OdawaraSource :
- Diabetes therapy : research, treatment and education of diabetes and related disorders [ 1869-6953 ] ; 2015.
Abstract
This study aimed to assess treatment satisfaction and self-reported health status in insulin-naïve patients with type 2 diabetes mellitus (T2DM) who started insulin glargine basal-supported oral therapy (BOT) with glycated hemoglobin (HbA1c) value of ≥6.5%, using data from Add-on Lantus(®) to Oral Hypoglycemic Agents 2 (ALOHA2) study, a 24-week single-arm, observational study of Japanese patients with T2DM, conducted as drug use surveillance in Japan.
DOI: 10.1007/s13300-015-0111-5
PubMed: 26040914
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Improved Treatment Satisfaction and Self-reported Health Status after Introduction of Basal-Supported Oral Therapy Using Insulin Glargine in Patients with Type 2 Diabetes: Sub-Analysis of ALOHA2 Study.</title><author><name sortKey="Tsukube, Shoko" sort="Tsukube, Shoko" uniqKey="Tsukube S" first="Shoko" last="Tsukube">Shoko Tsukube</name><affiliation><nlm:affiliation>Sanofi K.K., Tokyo Opera City Tower, 3-20-2 Nishi-shinjyuku, Shinjyuku-ku, Tokyo, 163-1488, Japan, DiabetesMedical.Sanofi@sanofi.com.</nlm:affiliation></affiliation></author><author><name sortKey="Ikeda, Yukio" sort="Ikeda, Yukio" uniqKey="Ikeda Y" first="Yukio" last="Ikeda">Yukio Ikeda</name></author><author><name sortKey="Kadowaki, Takashi" sort="Kadowaki, Takashi" uniqKey="Kadowaki T" first="Takashi" last="Kadowaki">Takashi Kadowaki</name></author><author><name sortKey="Odawara, Masato" sort="Odawara, Masato" uniqKey="Odawara M" first="Masato" last="Odawara">Masato Odawara</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="doi">10.1007/s13300-015-0111-5</idno><idno type="RBID">pubmed:26040914</idno><idno type="pmid">26040914</idno><idno type="wicri:Area/PubMed/Corpus">000077</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Improved Treatment Satisfaction and Self-reported Health Status after Introduction of Basal-Supported Oral Therapy Using Insulin Glargine in Patients with Type 2 Diabetes: Sub-Analysis of ALOHA2 Study.</title><author><name sortKey="Tsukube, Shoko" sort="Tsukube, Shoko" uniqKey="Tsukube S" first="Shoko" last="Tsukube">Shoko Tsukube</name><affiliation><nlm:affiliation>Sanofi K.K., Tokyo Opera City Tower, 3-20-2 Nishi-shinjyuku, Shinjyuku-ku, Tokyo, 163-1488, Japan, DiabetesMedical.Sanofi@sanofi.com.</nlm:affiliation></affiliation></author><author><name sortKey="Ikeda, Yukio" sort="Ikeda, Yukio" uniqKey="Ikeda Y" first="Yukio" last="Ikeda">Yukio Ikeda</name></author><author><name sortKey="Kadowaki, Takashi" sort="Kadowaki, Takashi" uniqKey="Kadowaki T" first="Takashi" last="Kadowaki">Takashi Kadowaki</name></author><author><name sortKey="Odawara, Masato" sort="Odawara, Masato" uniqKey="Odawara M" first="Masato" last="Odawara">Masato Odawara</name></author></analytic><series><title level="j">Diabetes therapy : research, treatment and education of diabetes and related disorders</title><idno type="ISSN">1869-6953</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">This study aimed to assess treatment satisfaction and self-reported health status in insulin-naïve patients with type 2 diabetes mellitus (T2DM) who started insulin glargine basal-supported oral therapy (BOT) with glycated hemoglobin (HbA1c) value of ≥6.5%, using data from Add-on Lantus(®) to Oral Hypoglycemic Agents 2 (ALOHA2) study, a 24-week single-arm, observational study of Japanese patients with T2DM, conducted as drug use surveillance in Japan.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="PubMed-not-MEDLINE"><PMID Version="1">26040914</PMID><DateCreated><Year>2015</Year><Month>06</Month><Day>24</Day></DateCreated><DateCompleted><Year>2015</Year><Month>06</Month><Day>24</Day></DateCompleted><DateRevised><Year>2015</Year><Month>07</Month><Day>01</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Print">1869-6953</ISSN><JournalIssue CitedMedium="Print"><Volume>6</Volume><Issue>2</Issue><PubDate><Year>2015</Year><Month>Jun</Month></PubDate></JournalIssue><Title>Diabetes therapy : research, treatment and education of diabetes and related disorders</Title><ISOAbbreviation>Diabetes Ther</ISOAbbreviation></Journal><ArticleTitle>Improved Treatment Satisfaction and Self-reported Health Status after Introduction of Basal-Supported Oral Therapy Using Insulin Glargine in Patients with Type 2 Diabetes: Sub-Analysis of ALOHA2 Study.</ArticleTitle><Pagination><MedlinePgn>153-71</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1007/s13300-015-0111-5</ELocationID><Abstract><AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">This study aimed to assess treatment satisfaction and self-reported health status in insulin-naïve patients with type 2 diabetes mellitus (T2DM) who started insulin glargine basal-supported oral therapy (BOT) with glycated hemoglobin (HbA1c) value of ≥6.5%, using data from Add-on Lantus(®) to Oral Hypoglycemic Agents 2 (ALOHA2) study, a 24-week single-arm, observational study of Japanese patients with T2DM, conducted as drug use surveillance in Japan.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Treatment satisfaction was measured using the Diabetes Treatment Satisfaction Questionnaire status version (DTSQs) and change version (DTSQc) and self-reported health status using EuroQol 5 Dimension (EQ-5D). The results were compared between the groups stratified by HbA1c level at the final evaluation point: target-achieved (<7.0%) and target-not-achieved groups (≥7.0%).</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">In 1251 patients (336 in the target-achieved group), scores of DTSQs, DTSQc, and EQ-5D indicated significant improvement from baseline to the final evaluation point (both P < 0.01). The mean change in DTSQs scale score, DTSQs item score, and EQ-5D index score, and mean DTSQc scale score were significantly improved in the target-achieved group compared with the target-not-achieved group (P < 0.05 for all). DTSQs scale score and HbA1c level showed the same pattern of chronological change. Data analysis in patients stratified by DTSQs score showed better glycemic control in the high satisfaction group.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Following insulin glargine BOT introduction, treatment satisfaction and health status were improved from patients' perspectives despite the need for daily injections. Based on the possible association between HbA1c 7.0% level achievement, treatment satisfaction, and health status, better glycemic control may be a key to successful treatment.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Tsukube</LastName><ForeName>Shoko</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Sanofi K.K., Tokyo Opera City Tower, 3-20-2 Nishi-shinjyuku, Shinjyuku-ku, Tokyo, 163-1488, Japan, DiabetesMedical.Sanofi@sanofi.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ikeda</LastName><ForeName>Yukio</ForeName><Initials>Y</Initials></Author><Author ValidYN="Y"><LastName>Kadowaki</LastName><ForeName>Takashi</ForeName><Initials>T</Initials></Author><Author ValidYN="Y"><LastName>Odawara</LastName><ForeName>Masato</ForeName><Initials>M</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2015</Year><Month>06</Month><Day>04</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Diabetes Ther</MedlineTA><NlmUniqueID>101539025</NlmUniqueID></MedlineJournalInfo><OtherID Source="NLM">PMC4478177</OtherID></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2015</Year><Month>4</Month><Day>20</Day></PubMedPubDate><PubMedPubDate PubStatus="aheadofprint"><Year>2015</Year><Month>6</Month><Day>4</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2015</Year><Month>6</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2015</Year><Month>6</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2015</Year><Month>6</Month><Day>5</Day><Hour>6</Hour><Minute>1</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="doi">10.1007/s13300-015-0111-5</ArticleId><ArticleId IdType="pubmed">26040914</ArticleId><ArticleId IdType="pmc">PMC4478177</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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