Structural basis of efficient contagion: measles variations on a theme by parainfluenza viruses
Identifieur interne : 000D62 ( Pmc/Corpus ); précédent : 000D61; suivant : 000D63Structural basis of efficient contagion: measles variations on a theme by parainfluenza viruses
Auteurs : Mathieu Mateo ; Chanakha K. Navaratnarajah ; Roberto CattaneoSource :
- Current opinion in virology [ 1879-6257 ] ; 2014.
Abstract
A quartet of attachment proteins and a trio of fusion protein subunits play the cell entry concert of parainfluenza viruses. While many of these viruses bind sialic acid to enter cells, wild type measles binds exclusively two tissue-specific proteins, the lymphatic receptor signaling lymphocytic activation molecule (SLAM), and the epithelial receptor nectin-4. SLAM binds near the stalk-head junction of the hemagglutinin. Nectin-4 binds a hydrophobic groove located between blades 4 and 5 of the hemagglutinin β-propeller head. The mutated vaccine strain hemagglutinin binds in addition the ubiquitous protein CD46, which explains attenuation. The measles virus entry concert has four movements.
Url:
DOI: 10.1016/j.coviro.2014.01.004
PubMed: 24492202
PubMed Central: 4028398
Links to Exploration step
PMC:4028398***** Acces problem to record *****\Le document en format XML
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Musique/explor/OperaV1/Data/Pmc/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000D62 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd -nk 000D62 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Musique |area= OperaV1 |flux= Pmc |étape= Corpus |type= RBID |clé= PMC:4028398 |texte= Structural basis of efficient contagion: measles variations on a theme by parainfluenza viruses }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/RBID.i -Sk "pubmed:24492202" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd \ | NlmPubMed2Wicri -a OperaV1
![]() | This area was generated with Dilib version V0.6.21. | ![]() |