OperaV1, PascalFrancis, Corpus, bibRecord, 000337

STEMI and NSTEMI : are they so different? 1 year outcomes in acute myocardial infarction as defined by the ESC/ACC definition (the OPERA registry). Commentary

Identifieur interne : 000337 ( PascalFrancis/Corpus ); précédent : 000336; suivant : 000338

STEMI and NSTEMI : are they so different? 1 year outcomes in acute myocardial infarction as defined by the ESC/ACC definition (the OPERA registry). Commentary

Auteurs : Christoph Bode ; Andreas Zirlik ; Gilles Montalescot ; Jean Dallongeville ; Eric Van Belle ; Stephanie Rouanet ; Cathrine Baulac ; Alexia Degrandsart ; Eric Vicaut

Source :

European heart journal [ 0195-668X ] ; 2007.

RBID : Pascal:07-0328157

Descripteurs français

Pascal (Inist)
- Infarctus myocarde, Pronostic, Evolution, Aigu, Définition, Registre, Mort, Prédicteur, Facteur prédictif, Prédiction, Appareil circulatoire, Cardiologie, Phlébologie.

English descriptors

KwdEn :
- Acute, Cardiology, Circulatory system, Death, Definition, Evolution, Myocardial infarction, Phlebology, Prediction, Predictive factor, Predictor, Prognosis, Register.

Abstract

Aims The ESC/ACC redefined myocardial infarction as any amount of necrosis caused by ischaemia. The aim of this study was to describe the management and outcomes using 'real-world' data taking the new definition of acute myocardial infarction into account. Methods and results A total of 2151 consecutive patients (76.0% men) with a myocardial infarction were enrolled at 56 centres in France. The median delay to presentation was shorter in patients with ST-segment elevation myocardial infarction (STEMI) vs. non-STEMI (NSTEMI) (4 vs. 7 h, P<0.0001). STEMI patients were more likely to receive fibrinolysis (28.9 vs. 0.7%, P< 0.0001) or undergo PCl (71.0 vs. 51.6%, P< 0.0001) but less likely to have bypass surgery (3.1 vs. 4.9%, P< 0.05). At discharge, patients with STEMI received more aggressive secondary prevention therapies than those with NSTEMI, which was not supported by differences in disease severity. A total of 1878 patients were followed-up for 1 year: 36.7% of STEMI and 41.5% of NSTEMI patients were rehospitalized (P= 0.05); 16% in both groups were revascularized. In-hospital mortality was similar (4.6 vs. 4.3%), and 1-year mortality was 9.0% in STEMI patients and 11.6% in NSTEMI patients (Log-Rank P= 0.09). Independent correlates of in-hospital mortality were untreated dyslipidaemia, advanced age, diabetes, and low blood pressure. The strongest predictors of 1 -year mortality were heart failure and age. Similar predictors were found in STEMI and NSTEMI subgroups. Conclusions Despite different management, patients with STEMI and NSTEMI have similar prognoses and independent correlates of outcome. These findings support the new definition of myocardial infarction.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A11	`01`	`1`		`@1 BODE (Christoph) @9 comment.`
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C01	`01`		`ENG`	@0 Aims The ESC/ACC redefined myocardial infarction as any amount of necrosis caused by ischaemia. The aim of this study was to describe the management and outcomes using 'real-world' data taking the new definition of acute myocardial infarction into account. Methods and results A total of 2151 consecutive patients (76.0% men) with a myocardial infarction were enrolled at 56 centres in France. The median delay to presentation was shorter in patients with ST-segment elevation myocardial infarction (STEMI) vs. non-STEMI (NSTEMI) (4 vs. 7 h, P<0.0001). STEMI patients were more likely to receive fibrinolysis (28.9 vs. 0.7%, P< 0.0001) or undergo PCl (71.0 vs. 51.6%, P< 0.0001) but less likely to have bypass surgery (3.1 vs. 4.9%, P< 0.05). At discharge, patients with STEMI received more aggressive secondary prevention therapies than those with NSTEMI, which was not supported by differences in disease severity. A total of 1878 patients were followed-up for 1 year: 36.7% of STEMI and 41.5% of NSTEMI patients were rehospitalized (P= 0.05); 16% in both groups were revascularized. In-hospital mortality was similar (4.6 vs. 4.3%), and 1-year mortality was 9.0% in STEMI patients and 11.6% in NSTEMI patients (Log-Rank P= 0.09). Independent correlates of in-hospital mortality were untreated dyslipidaemia, advanced age, diabetes, and low blood pressure. The strongest predictors of 1 -year mortality were heart failure and age. Similar predictors were found in STEMI and NSTEMI subgroups. Conclusions Despite different management, patients with STEMI and NSTEMI have similar prognoses and independent correlates of outcome. These findings support the new definition of myocardial infarction.
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Format Inist (serveur)

NO :	PASCAL 07-0328157 INIST
ET :	STEMI and NSTEMI : are they so different? 1 year outcomes in acute myocardial infarction as defined by the ESC/ACC definition (the OPERA registry). Commentary
AU :	BODE (Christoph); ZIRLIK (Andreas); MONTALESCOT (Gilles); DALLONGEVILLE (Jean); VAN BELLE (Eric); ROUANET (Stephanie); BAULAC (Cathrine); DEGRANDSART (Alexia); VICAUT (Eric)
AF :	Department of Cardiology and Angiology, III. Medizinische Universitaetsklinik, Hugstetter Str. 55/79106 Freiburg/Allemagne (1 aut., 2 aut.); Institut de Cardiologie and INSERM U856, Pitié-Salpétrière University Hospital, AP-HP, 47 Boulevard de l'Hôpital/Paris 75013/France (3 aut.); Institut Pasteur and INSERM U508/Lille/France (4 aut.); University Hospital and INSERM ERI9/Lille/France (5 aut.); THERAPHARM Recherches/Boulogne -Billancourt/France (6 aut.); Pfizer/Paris/France (7 aut., 8 aut.); Clinical Research Unit, Fernand Vidal Hospital/Paris/France (9 aut.)
DT :	Publication en série; Article; Commentaire; Niveau analytique
SO :	European heart journal; ISSN 0195-668X; Royaume-Uni; Da. 2007; Vol. 28; No. 12; 1403-1404, 1409-1417 [11 p.]; Bibl. 43 ref.
LA :	Anglais
EA :	Aims The ESC/ACC redefined myocardial infarction as any amount of necrosis caused by ischaemia. The aim of this study was to describe the management and outcomes using 'real-world' data taking the new definition of acute myocardial infarction into account. Methods and results A total of 2151 consecutive patients (76.0% men) with a myocardial infarction were enrolled at 56 centres in France. The median delay to presentation was shorter in patients with ST-segment elevation myocardial infarction (STEMI) vs. non-STEMI (NSTEMI) (4 vs. 7 h, P<0.0001). STEMI patients were more likely to receive fibrinolysis (28.9 vs. 0.7%, P< 0.0001) or undergo PCl (71.0 vs. 51.6%, P< 0.0001) but less likely to have bypass surgery (3.1 vs. 4.9%, P< 0.05). At discharge, patients with STEMI received more aggressive secondary prevention therapies than those with NSTEMI, which was not supported by differences in disease severity. A total of 1878 patients were followed-up for 1 year: 36.7% of STEMI and 41.5% of NSTEMI patients were rehospitalized (P= 0.05); 16% in both groups were revascularized. In-hospital mortality was similar (4.6 vs. 4.3%), and 1-year mortality was 9.0% in STEMI patients and 11.6% in NSTEMI patients (Log-Rank P= 0.09). Independent correlates of in-hospital mortality were untreated dyslipidaemia, advanced age, diabetes, and low blood pressure. The strongest predictors of 1 -year mortality were heart failure and age. Similar predictors were found in STEMI and NSTEMI subgroups. Conclusions Despite different management, patients with STEMI and NSTEMI have similar prognoses and independent correlates of outcome. These findings support the new definition of myocardial infarction.
CC :	002B12A03; 002B12A05
FD :	Infarctus myocarde; Pronostic; Evolution; Aigu; Définition; Registre; Mort; Prédicteur; Facteur prédictif; Prédiction; Appareil circulatoire; Cardiologie; Phlébologie
FG :	Appareil circulatoire pathologie; Myocarde pathologie; Cardiopathie
ED :	Myocardial infarction; Prognosis; Evolution; Acute; Definition; Register; Death; Predictor; Predictive factor; Prediction; Circulatory system; Cardiology; Phlebology
EG :	Cardiovascular disease; Myocardial disease; Heart disease
SD :	Infarto miocardio; Pronóstico; Evolución; Agudo; Definición; Registro; Muerte; Predictor; Factor predictivo; Predicción; Aparato circulatorio; Cardiología; Flebología
LO :	INIST-18785.354000146524900020
ID :	07-0328157

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Le document en format XML

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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acute</term>
<term>Cardiology</term>
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<term>Definition</term>
<term>Evolution</term>
<term>Myocardial infarction</term>
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<term>Predictive factor</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Infarctus myocarde</term>
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<term>Registre</term>
<term>Mort</term>
<term>Prédicteur</term>
<term>Facteur prédictif</term>
<term>Prédiction</term>
<term>Appareil circulatoire</term>
<term>Cardiologie</term>
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<front><div type="abstract" xml:lang="en">Aims The ESC/ACC redefined myocardial infarction as any amount of necrosis caused by ischaemia. The aim of this study was to describe the management and outcomes using 'real-world' data taking the new definition of acute myocardial infarction into account. Methods and results A total of 2151 consecutive patients (76.0% men) with a myocardial infarction were enrolled at 56 centres in France. The median delay to presentation was shorter in patients with ST-segment elevation myocardial infarction (STEMI) vs. non-STEMI (NSTEMI) (4 vs. 7 h, P<0.0001). STEMI patients were more likely to receive fibrinolysis (28.9 vs. 0.7%, P< 0.0001) or undergo PCl (71.0 vs. 51.6%, P< 0.0001) but less likely to have bypass surgery (3.1 vs. 4.9%, P< 0.05). At discharge, patients with STEMI received more aggressive secondary prevention therapies than those with NSTEMI, which was not supported by differences in disease severity. A total of 1878 patients were followed-up for 1 year: 36.7% of STEMI and 41.5% of NSTEMI patients were rehospitalized (P= 0.05); 16% in both groups were revascularized. In-hospital mortality was similar (4.6 vs. 4.3%), and 1-year mortality was 9.0% in STEMI patients and 11.6% in NSTEMI patients (Log-Rank P= 0.09). Independent correlates of in-hospital mortality were untreated dyslipidaemia, advanced age, diabetes, and low blood pressure. The strongest predictors of 1 -year mortality were heart failure and age. Similar predictors were found in STEMI and NSTEMI subgroups. Conclusions Despite different management, patients with STEMI and NSTEMI have similar prognoses and independent correlates of outcome. These findings support the new definition of myocardial infarction.</div>
</front>
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<inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0195-668X</s0>
</fA01>
<fA03 i2="1"><s0>Eur. heart j.</s0>
</fA03>
<fA05><s2>28</s2>
</fA05>
<fA06><s2>12</s2>
</fA06>
<fA08 i1="01" i2="1" l="ENG"><s1>STEMI and NSTEMI : are they so different? 1 year outcomes in acute myocardial infarction as defined by the ESC/ACC definition (the OPERA registry). Commentary</s1>
</fA08>
<fA11 i1="01" i2="1"><s1>BODE (Christoph)</s1>
<s9>comment.</s9>
</fA11>
<fA11 i1="02" i2="1"><s1>ZIRLIK (Andreas)</s1>
<s9>comment.</s9>
</fA11>
<fA11 i1="03" i2="1"><s1>MONTALESCOT (Gilles)</s1>
</fA11>
<fA11 i1="04" i2="1"><s1>DALLONGEVILLE (Jean)</s1>
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<fA11 i1="05" i2="1"><s1>VAN BELLE (Eric)</s1>
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<fA11 i1="06" i2="1"><s1>ROUANET (Stephanie)</s1>
</fA11>
<fA11 i1="07" i2="1"><s1>BAULAC (Cathrine)</s1>
</fA11>
<fA11 i1="08" i2="1"><s1>DEGRANDSART (Alexia)</s1>
</fA11>
<fA11 i1="09" i2="1"><s1>VICAUT (Eric)</s1>
</fA11>
<fA14 i1="01"><s1>Department of Cardiology and Angiology, III. Medizinische Universitaetsklinik, Hugstetter Str. 55</s1>
<s2>79106 Freiburg</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
</fA14>
<fA14 i1="02"><s1>Institut de Cardiologie and INSERM U856, Pitié-Salpétrière University Hospital, AP-HP, 47 Boulevard de l'Hôpital</s1>
<s2>Paris 75013</s2>
<s3>FRA</s3>
<sZ>3 aut.</sZ>
</fA14>
<fA14 i1="03"><s1>Institut Pasteur and INSERM U508</s1>
<s2>Lille</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
</fA14>
<fA14 i1="04"><s1>University Hospital and INSERM ERI9</s1>
<s2>Lille</s2>
<s3>FRA</s3>
<sZ>5 aut.</sZ>
</fA14>
<fA14 i1="05"><s1>THERAPHARM Recherches</s1>
<s2>Boulogne -Billancourt</s2>
<s3>FRA</s3>
<sZ>6 aut.</sZ>
</fA14>
<fA14 i1="06"><s1>Pfizer</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</fA14>
<fA14 i1="07"><s1>Clinical Research Unit, Fernand Vidal Hospital</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>9 aut.</sZ>
</fA14>
<fA17 i1="01" i2="1"><s1>OPERA Investigators</s1>
<s3>INC</s3>
</fA17>
<fA20><s2>1403-1404, 1409-1417 [11 p.]</s2>
</fA20>
<fA21><s1>2007</s1>
</fA21>
<fA23 i1="01"><s0>ENG</s0>
</fA23>
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<s2>18785</s2>
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<s1>© 2007 INIST-CNRS. All rights reserved.</s1>
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<fA60><s1>P</s1>
<s3>AR</s3>
<s3>CT</s3>
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<fA64 i1="01" i2="1"><s0>European heart journal</s0>
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<fC01 i1="01" l="ENG"><s0>Aims The ESC/ACC redefined myocardial infarction as any amount of necrosis caused by ischaemia. The aim of this study was to describe the management and outcomes using 'real-world' data taking the new definition of acute myocardial infarction into account. Methods and results A total of 2151 consecutive patients (76.0% men) with a myocardial infarction were enrolled at 56 centres in France. The median delay to presentation was shorter in patients with ST-segment elevation myocardial infarction (STEMI) vs. non-STEMI (NSTEMI) (4 vs. 7 h, P<0.0001). STEMI patients were more likely to receive fibrinolysis (28.9 vs. 0.7%, P< 0.0001) or undergo PCl (71.0 vs. 51.6%, P< 0.0001) but less likely to have bypass surgery (3.1 vs. 4.9%, P< 0.05). At discharge, patients with STEMI received more aggressive secondary prevention therapies than those with NSTEMI, which was not supported by differences in disease severity. A total of 1878 patients were followed-up for 1 year: 36.7% of STEMI and 41.5% of NSTEMI patients were rehospitalized (P= 0.05); 16% in both groups were revascularized. In-hospital mortality was similar (4.6 vs. 4.3%), and 1-year mortality was 9.0% in STEMI patients and 11.6% in NSTEMI patients (Log-Rank P= 0.09). Independent correlates of in-hospital mortality were untreated dyslipidaemia, advanced age, diabetes, and low blood pressure. The strongest predictors of 1 -year mortality were heart failure and age. Similar predictors were found in STEMI and NSTEMI subgroups. Conclusions Despite different management, patients with STEMI and NSTEMI have similar prognoses and independent correlates of outcome. These findings support the new definition of myocardial infarction.</s0>
</fC01>
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<s2>NM</s2>
<s5>01</s5>
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<s2>NM</s2>
<s5>01</s5>
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<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Pronostic</s0>
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<s5>09</s5>
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<fC03 i1="03" i2="X" l="FRE"><s0>Evolution</s0>
<s5>10</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Evolution</s0>
<s5>10</s5>
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<fC03 i1="03" i2="X" l="SPA"><s0>Evolución</s0>
<s5>10</s5>
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<s5>11</s5>
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<s5>11</s5>
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<fC03 i1="04" i2="X" l="SPA"><s0>Agudo</s0>
<s5>11</s5>
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<s5>12</s5>
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<s5>13</s5>
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<s5>13</s5>
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<s5>13</s5>
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<s5>14</s5>
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<fC03 i1="08" i2="X" l="FRE"><s0>Prédicteur</s0>
<s5>15</s5>
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<fC03 i1="08" i2="X" l="ENG"><s0>Predictor</s0>
<s5>15</s5>
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<fC03 i1="08" i2="X" l="SPA"><s0>Predictor</s0>
<s5>15</s5>
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<fC03 i1="09" i2="X" l="FRE"><s0>Facteur prédictif</s0>
<s5>16</s5>
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<s5>16</s5>
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<fC03 i1="09" i2="X" l="SPA"><s0>Factor predictivo</s0>
<s5>16</s5>
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<fC03 i1="10" i2="X" l="FRE"><s0>Prédiction</s0>
<s5>17</s5>
</fC03>
<fC03 i1="10" i2="X" l="ENG"><s0>Prediction</s0>
<s5>17</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA"><s0>Predicción</s0>
<s5>17</s5>
</fC03>
<fC03 i1="11" i2="X" l="FRE"><s0>Appareil circulatoire</s0>
<s5>18</s5>
</fC03>
<fC03 i1="11" i2="X" l="ENG"><s0>Circulatory system</s0>
<s5>18</s5>
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<s5>18</s5>
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<s5>19</s5>
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<s5>19</s5>
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<s5>19</s5>
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<s5>20</s5>
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<s5>20</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Appareil circulatoire pathologie</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Cardiovascular disease</s0>
<s5>37</s5>
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<s5>37</s5>
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<s5>38</s5>
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<s5>38</s5>
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<s5>39</s5>
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<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Cardiopatía</s0>
<s5>39</s5>
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<fN21><s1>211</s1>
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<server><NO>PASCAL 07-0328157 INIST</NO>
<ET>STEMI and NSTEMI : are they so different? 1 year outcomes in acute myocardial infarction as defined by the ESC/ACC definition (the OPERA registry). Commentary</ET>
<AU>BODE (Christoph); ZIRLIK (Andreas); MONTALESCOT (Gilles); DALLONGEVILLE (Jean); VAN BELLE (Eric); ROUANET (Stephanie); BAULAC (Cathrine); DEGRANDSART (Alexia); VICAUT (Eric)</AU>
<AF>Department of Cardiology and Angiology, III. Medizinische Universitaetsklinik, Hugstetter Str. 55/79106 Freiburg/Allemagne (1 aut., 2 aut.); Institut de Cardiologie and INSERM U856, Pitié-Salpétrière University Hospital, AP-HP, 47 Boulevard de l'Hôpital/Paris 75013/France (3 aut.); Institut Pasteur and INSERM U508/Lille/France (4 aut.); University Hospital and INSERM ERI9/Lille/France (5 aut.); THERAPHARM Recherches/Boulogne -Billancourt/France (6 aut.); Pfizer/Paris/France (7 aut., 8 aut.); Clinical Research Unit, Fernand Vidal Hospital/Paris/France (9 aut.)</AF>
<DT>Publication en série; Article; Commentaire; Niveau analytique</DT>
<SO>European heart journal; ISSN 0195-668X; Royaume-Uni; Da. 2007; Vol. 28; No. 12; 1403-1404, 1409-1417 [11 p.]; Bibl. 43 ref.</SO>
<LA>Anglais</LA>
<EA>Aims The ESC/ACC redefined myocardial infarction as any amount of necrosis caused by ischaemia. The aim of this study was to describe the management and outcomes using 'real-world' data taking the new definition of acute myocardial infarction into account. Methods and results A total of 2151 consecutive patients (76.0% men) with a myocardial infarction were enrolled at 56 centres in France. The median delay to presentation was shorter in patients with ST-segment elevation myocardial infarction (STEMI) vs. non-STEMI (NSTEMI) (4 vs. 7 h, P<0.0001). STEMI patients were more likely to receive fibrinolysis (28.9 vs. 0.7%, P< 0.0001) or undergo PCl (71.0 vs. 51.6%, P< 0.0001) but less likely to have bypass surgery (3.1 vs. 4.9%, P< 0.05). At discharge, patients with STEMI received more aggressive secondary prevention therapies than those with NSTEMI, which was not supported by differences in disease severity. A total of 1878 patients were followed-up for 1 year: 36.7% of STEMI and 41.5% of NSTEMI patients were rehospitalized (P= 0.05); 16% in both groups were revascularized. In-hospital mortality was similar (4.6 vs. 4.3%), and 1-year mortality was 9.0% in STEMI patients and 11.6% in NSTEMI patients (Log-Rank P= 0.09). Independent correlates of in-hospital mortality were untreated dyslipidaemia, advanced age, diabetes, and low blood pressure. The strongest predictors of 1 -year mortality were heart failure and age. Similar predictors were found in STEMI and NSTEMI subgroups. Conclusions Despite different management, patients with STEMI and NSTEMI have similar prognoses and independent correlates of outcome. These findings support the new definition of myocardial infarction.</EA>
<CC>002B12A03; 002B12A05</CC>
<FD>Infarctus myocarde; Pronostic; Evolution; Aigu; Définition; Registre; Mort; Prédicteur; Facteur prédictif; Prédiction; Appareil circulatoire; Cardiologie; Phlébologie</FD>
<FG>Appareil circulatoire pathologie; Myocarde pathologie; Cardiopathie</FG>
<ED>Myocardial infarction; Prognosis; Evolution; Acute; Definition; Register; Death; Predictor; Predictive factor; Prediction; Circulatory system; Cardiology; Phlebology</ED>
<EG>Cardiovascular disease; Myocardial disease; Heart disease</EG>
<SD>Infarto miocardio; Pronóstico; Evolución; Agudo; Definición; Registro; Muerte; Predictor; Factor predictivo; Predicción; Aparato circulatorio; Cardiología; Flebología</SD>
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STEMI and NSTEMI : are they so different? 1 year outcomes in acute myocardial infarction as defined by the ESC/ACC definition (the OPERA registry). Commentary

STEMI and NSTEMI : are they so different? 1 year outcomes in acute myocardial infarction as defined by the ESC/ACC definition (the OPERA registry). Commentary

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