The OPERA trial - comparison of early nasal high flow oxygen therapy with standard care for prevention of postoperative hypoxemia after abdominal surgery: study protocol for a multicenter randomized controlled trial.
Identifieur interne : 000B26 ( Ncbi/Checkpoint ); précédent : 000B25; suivant : 000B27The OPERA trial - comparison of early nasal high flow oxygen therapy with standard care for prevention of postoperative hypoxemia after abdominal surgery: study protocol for a multicenter randomized controlled trial.
Auteurs : Emmanuel Futier [France] ; Catherine Paugam-Burtz ; Jean-Michel Constantin ; Bruno Pereira ; Samir JaberSource :
- Trials ; 2013.
Descripteurs français
- Wicri :
- geographic : France.
English descriptors
- KwdEn :
- Abdomen (surgery), Airway Extubation, Anoxia (etiology), Anoxia (prevention & control), Clinical Protocols, France, Humans, Intubation, Intratracheal, Oxygen Inhalation Therapy (methods), Postoperative Complications (prevention & control), Research Design, Risk Factors, Time Factors, Treatment Outcome.
- MESH :
- geographic : France.
- etiology : Anoxia.
- methods : Oxygen Inhalation Therapy.
- prevention & control : Anoxia, Postoperative Complications.
- surgery : Abdomen.
- Airway Extubation, Clinical Protocols, Humans, Intubation, Intratracheal, Research Design, Risk Factors, Time Factors, Treatment Outcome.
Abstract
Respiratory support following postoperative extubation is of major importance to prevent hypoxemia and subsequent respiratory failure and reintubation. High-flow nasal cannula oxygen (HFNC) delivers a flow-dependent positive airway pressure and improves oxygenation by increasing end-expiratory lung volume. Whether application of HFNC may have therapeutic advantages over conventional oxygen therapy for respiratory support in the early postextubation surgical period remains to be established.
DOI: 10.1186/1745-6215-14-341
PubMed: 24138710
Affiliations:
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pubmed:24138710Le document en format XML
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<author><name sortKey="Futier, Emmanuel" sort="Futier, Emmanuel" uniqKey="Futier E" first="Emmanuel" last="Futier">Emmanuel Futier</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Anesthesiology and Critical Care Medicine, Estaing Hospital, University Teaching Hospital of Clermont-Ferrand, 1, place Lucie Aubrac, Clermont-Ferrand Cedex 1, 63000, France. efutier@chu-clermontferrand.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Anesthesiology and Critical Care Medicine, Estaing Hospital, University Teaching Hospital of Clermont-Ferrand, 1, place Lucie Aubrac, Clermont-Ferrand Cedex 1, 63000</wicri:regionArea>
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<author><name sortKey="Paugam Burtz, Catherine" sort="Paugam Burtz, Catherine" uniqKey="Paugam Burtz C" first="Catherine" last="Paugam-Burtz">Catherine Paugam-Burtz</name>
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<author><name sortKey="Constantin, Jean Michel" sort="Constantin, Jean Michel" uniqKey="Constantin J" first="Jean-Michel" last="Constantin">Jean-Michel Constantin</name>
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<author><name sortKey="Pereira, Bruno" sort="Pereira, Bruno" uniqKey="Pereira B" first="Bruno" last="Pereira">Bruno Pereira</name>
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<author><name sortKey="Jaber, Samir" sort="Jaber, Samir" uniqKey="Jaber S" first="Samir" last="Jaber">Samir Jaber</name>
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<wicri:regionArea>Department of Anesthesiology and Critical Care Medicine, Estaing Hospital, University Teaching Hospital of Clermont-Ferrand, 1, place Lucie Aubrac, Clermont-Ferrand Cedex 1, 63000</wicri:regionArea>
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<series><title level="j">Trials</title>
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<term>Airway Extubation</term>
<term>Anoxia (etiology)</term>
<term>Anoxia (prevention & control)</term>
<term>Clinical Protocols</term>
<term>France</term>
<term>Humans</term>
<term>Intubation, Intratracheal</term>
<term>Oxygen Inhalation Therapy (methods)</term>
<term>Postoperative Complications (prevention & control)</term>
<term>Research Design</term>
<term>Risk Factors</term>
<term>Time Factors</term>
<term>Treatment Outcome</term>
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<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Anoxia</term>
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<term>Postoperative Complications</term>
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<term>Clinical Protocols</term>
<term>Humans</term>
<term>Intubation, Intratracheal</term>
<term>Research Design</term>
<term>Risk Factors</term>
<term>Time Factors</term>
<term>Treatment Outcome</term>
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<front><div type="abstract" xml:lang="en">Respiratory support following postoperative extubation is of major importance to prevent hypoxemia and subsequent respiratory failure and reintubation. High-flow nasal cannula oxygen (HFNC) delivers a flow-dependent positive airway pressure and improves oxygenation by increasing end-expiratory lung volume. Whether application of HFNC may have therapeutic advantages over conventional oxygen therapy for respiratory support in the early postextubation surgical period remains to be established.</div>
</front>
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<affiliations><list><country><li>France</li>
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<region><li>Auvergne</li>
<li>Auvergne-Rhône-Alpes</li>
</region>
</list>
<tree><noCountry><name sortKey="Constantin, Jean Michel" sort="Constantin, Jean Michel" uniqKey="Constantin J" first="Jean-Michel" last="Constantin">Jean-Michel Constantin</name>
<name sortKey="Jaber, Samir" sort="Jaber, Samir" uniqKey="Jaber S" first="Samir" last="Jaber">Samir Jaber</name>
<name sortKey="Paugam Burtz, Catherine" sort="Paugam Burtz, Catherine" uniqKey="Paugam Burtz C" first="Catherine" last="Paugam-Burtz">Catherine Paugam-Burtz</name>
<name sortKey="Pereira, Bruno" sort="Pereira, Bruno" uniqKey="Pereira B" first="Bruno" last="Pereira">Bruno Pereira</name>
</noCountry>
<country name="France"><region name="Auvergne-Rhône-Alpes"><name sortKey="Futier, Emmanuel" sort="Futier, Emmanuel" uniqKey="Futier E" first="Emmanuel" last="Futier">Emmanuel Futier</name>
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