OPERA: use of pegylated interferon plus ribavirin for treating HCV-HIV coinfection in interferon-naive patients.
Identifieur interne : 000358 ( Main/Curation ); précédent : 000357; suivant : 000359OPERA: use of pegylated interferon plus ribavirin for treating HCV-HIV coinfection in interferon-naive patients.
Auteurs : Giampiero Carosi [Italie] ; Raffaele Bruno ; Giuseppe Cariti ; Paola Nasta ; Roberto Gulminetti ; Massimo Galli ; Gioacchino Angarano ; Gabriella Verucchi ; Emanuele Pontali ; Amedeo Capetti ; Enzo Raise ; Veronica Ravasio ; Ivana Maida ; Claudio Iannacone ; Antonietta Caputo ; Massimo PuotiSource :
- Antiviral therapy ; 2014.
English descriptors
- KwdEn :
- Adolescent, Adult, Aged, Antiretroviral Therapy, Highly Active, CD4 Lymphocyte Count, Coinfection, Drug Therapy, Combination, Female, Genotype, HIV Infections (drug therapy), HIV Infections (immunology), HIV Infections (virology), Hepacivirus (genetics), Hepatitis C (drug therapy), Hepatitis C (virology), Humans, Interferon-alpha (administration & dosage), Interferon-alpha (adverse effects), Interferon-alpha (therapeutic use), Liver (pathology), Liver (virology), Male, Middle Aged, Polyethylene Glycols (administration & dosage), Polyethylene Glycols (adverse effects), Polyethylene Glycols (therapeutic use), Prospective Studies, Recombinant Proteins (administration & dosage), Recombinant Proteins (adverse effects), Recombinant Proteins (therapeutic use), Recurrence, Ribavirin (administration & dosage), Ribavirin (adverse effects), Ribavirin (therapeutic use), Treatment Outcome, Viral Load, Young Adult.
- MESH :
- chemical , administration & dosage : Interferon-alpha, Polyethylene Glycols, Recombinant Proteins, Ribavirin.
- chemical , adverse effects : Interferon-alpha, Polyethylene Glycols, Recombinant Proteins, Ribavirin.
- drug therapy : HIV Infections, Hepatitis C.
- genetics : Hepacivirus.
- immunology : HIV Infections.
- pathology : Liver.
- chemical , therapeutic use : Interferon-alpha, Polyethylene Glycols, Recombinant Proteins, Ribavirin.
- virology : HIV Infections, Hepatitis C, Liver.
- Adolescent, Adult, Aged, Antiretroviral Therapy, Highly Active, CD4 Lymphocyte Count, Coinfection, Drug Therapy, Combination, Female, Genotype, Humans, Male, Middle Aged, Prospective Studies, Recurrence, Treatment Outcome, Viral Load, Young Adult.
Abstract
The Optimized Pegylated interferons Efficacy and anti-Retroviral Approach (OPERA) study aimed to assess the efficacy and safety profile of treatment with pegylated interferons (PEG-IFNs) in interferon-naive patients with chronic HCV and HIV infection in routine clinical practice.
DOI: 10.3851/IMP2757
PubMed: 24583976
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pubmed:24583976Le document en format XML
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<author><name sortKey="Carosi, Giampiero" sort="Carosi, Giampiero" uniqKey="Carosi G" first="Giampiero" last="Carosi">Giampiero Carosi</name>
<affiliation wicri:level="1"><nlm:affiliation>Institute of Infectious and Tropical Diseases, University of Brescia, Brescia, Italy.</nlm:affiliation>
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<series><title level="j">Antiviral therapy</title>
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<term>Adult</term>
<term>Aged</term>
<term>Antiretroviral Therapy, Highly Active</term>
<term>CD4 Lymphocyte Count</term>
<term>Coinfection</term>
<term>Drug Therapy, Combination</term>
<term>Female</term>
<term>Genotype</term>
<term>HIV Infections (drug therapy)</term>
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<term>Interferon-alpha (adverse effects)</term>
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<term>Liver (pathology)</term>
<term>Liver (virology)</term>
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<term>Middle Aged</term>
<term>Polyethylene Glycols (administration & dosage)</term>
<term>Polyethylene Glycols (adverse effects)</term>
<term>Polyethylene Glycols (therapeutic use)</term>
<term>Prospective Studies</term>
<term>Recombinant Proteins (administration & dosage)</term>
<term>Recombinant Proteins (adverse effects)</term>
<term>Recombinant Proteins (therapeutic use)</term>
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<term>Ribavirin (therapeutic use)</term>
<term>Treatment Outcome</term>
<term>Viral Load</term>
<term>Young Adult</term>
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<term>Recombinant Proteins</term>
<term>Ribavirin</term>
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<term>Polyethylene Glycols</term>
<term>Recombinant Proteins</term>
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<term>Hepatitis C</term>
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<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>HIV Infections</term>
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<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Interferon-alpha</term>
<term>Polyethylene Glycols</term>
<term>Recombinant Proteins</term>
<term>Ribavirin</term>
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<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>HIV Infections</term>
<term>Hepatitis C</term>
<term>Liver</term>
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<term>Adult</term>
<term>Aged</term>
<term>Antiretroviral Therapy, Highly Active</term>
<term>CD4 Lymphocyte Count</term>
<term>Coinfection</term>
<term>Drug Therapy, Combination</term>
<term>Female</term>
<term>Genotype</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Prospective Studies</term>
<term>Recurrence</term>
<term>Treatment Outcome</term>
<term>Viral Load</term>
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<front><div type="abstract" xml:lang="en">The Optimized Pegylated interferons Efficacy and anti-Retroviral Approach (OPERA) study aimed to assess the efficacy and safety profile of treatment with pegylated interferons (PEG-IFNs) in interferon-naive patients with chronic HCV and HIV infection in routine clinical practice.</div>
</front>
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