Na-Ca + K exchanger and Ca2+ homeostasis in retinal rod outer segments: Inactivation of the Ca2+ efflux mode and possible involvement of intracellular Ca2+ stores in Ca2+ homeostasis
Identifieur interne : 000C90 ( Main/Exploration ); précédent : 000C89; suivant : 000C91Na-Ca + K exchanger and Ca2+ homeostasis in retinal rod outer segments: Inactivation of the Ca2+ efflux mode and possible involvement of intracellular Ca2+ stores in Ca2+ homeostasis
Auteurs : Paul P. M. Schnetkamp [Canada]Source :
- Behavioral and Brain Sciences [ 0140-525X ] ; 1995-09.
Abstract
Inactivation of the Ca2+ extrusion mode of the retinal rod Na- Ca + K exchanger is suggested to be the mechanism that prevents lowering of cytosolic free Ca2+ to < 1 nM when rod cells are saturated for a prolonged time under bright light conditions. Under these conditions, Ca2+ fluxes across disk membranes can contribute significantly to Ca2+ homeostasis in rods.
Url:
DOI: 10.1017/S0140525X00039455
Affiliations:
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Le document en format XML
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<front><div type="abstract">Inactivation of the Ca2+ extrusion mode of the retinal rod Na- Ca + K exchanger is suggested to be the mechanism that prevents lowering of cytosolic free Ca2+ to < 1 nM when rod cells are saturated for a prolonged time under bright light conditions. Under these conditions, Ca2+ fluxes across disk membranes can contribute significantly to Ca2+ homeostasis in rods.</div>
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