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Na-Ca + K exchanger and Ca2+ homeostasis in retinal rod outer segments: Inactivation of the Ca2+ efflux mode and possible involvement of intracellular Ca2+ stores in Ca2+ homeostasis

Identifieur interne : 000C90 ( Main/Exploration ); précédent : 000C89; suivant : 000C91

Na-Ca + K exchanger and Ca2+ homeostasis in retinal rod outer segments: Inactivation of the Ca2+ efflux mode and possible involvement of intracellular Ca2+ stores in Ca2+ homeostasis

Auteurs : Paul P. M. Schnetkamp [Canada]

Source :

RBID : ISTEX:6D3C0ADB5B8F87C57B3C1DE7AB644EB22B84F53C

Abstract

Inactivation of the Ca2+ extrusion mode of the retinal rod Na- Ca + K exchanger is suggested to be the mechanism that prevents lowering of cytosolic free Ca2+ to < 1 nM when rod cells are saturated for a prolonged time under bright light conditions. Under these conditions, Ca2+ fluxes across disk membranes can contribute significantly to Ca2+ homeostasis in rods.

Url:
DOI: 10.1017/S0140525X00039455


Affiliations:


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Le document en format XML

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   |texte=   Na-Ca + K exchanger and Ca2+ homeostasis in retinal rod outer segments: Inactivation of the Ca2+ efflux mode and possible involvement of intracellular Ca2+ stores in Ca2+ homeostasis
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