MozartV1, PubMed, Checkpoint, bibRecord, 000034

Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention: the MOZART (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy) randomized controlled trial.

Identifieur interne : 000034 ( PubMed/Checkpoint ); précédent : 000033; suivant : 000035

Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention: the MOZART (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy) randomized controlled trial.

Auteurs : José Mariani [Brésil] ; Cristiano Guedes [Brésil] ; Paulo Soares [Brésil] ; Silvio Zalc [Brésil] ; Carlos M. Campos [Pays-Bas] ; Augusto C. Lopes [États-Unis] ; André G. Spadaro [Brésil] ; Marco A. Perin [Brésil] ; Antonio Esteves Filho [Brésil] ; Celso K. Takimura [Brésil] ; Expedito Ribeiro [Brésil] ; Roberto Kalil-Filho [Brésil] ; Elazer R. Edelman [États-Unis] ; Patrick W. Serruys [Royaume-Uni] ; Pedro A. Lemos [Brésil]

Source :

JACC. Cardiovascular interventions ; 2014.

RBID : pubmed:25326742

English descriptors

KwdEn :
- Acute Kidney Injury (blood), Acute Kidney Injury (chemically induced), Acute Kidney Injury (diagnosis), Acute Kidney Injury (prevention & control), Aged, Biomarkers (blood), Contrast Media (adverse effects), Coronary Angiography (adverse effects), Coronary Artery Disease (radiography), Coronary Artery Disease (therapy), Coronary Artery Disease (ultrasonography), Creatinine (blood), Female, Humans, Iohexol (adverse effects), Iohexol (analogs & derivatives), Male, Middle Aged, Percutaneous Coronary Intervention (adverse effects), Percutaneous Coronary Intervention (methods), Risk Factors, Time Factors, Treatment Outcome, Triiodobenzoic Acids (adverse effects), Ultrasonography, Interventional.
MESH :
- chemical , adverse effects : Contrast Media, Iohexol, Triiodobenzoic Acids.
- chemical , analogs & derivatives : Iohexol.
- chemical , blood : Biomarkers, Creatinine.
- adverse effects : Coronary Angiography, Percutaneous Coronary Intervention.
- blood : Acute Kidney Injury.
- chemically induced : Acute Kidney Injury.
- diagnosis : Acute Kidney Injury.
- methods : Percutaneous Coronary Intervention.
- prevention & control : Acute Kidney Injury.
- radiography : Coronary Artery Disease.
- therapy : Coronary Artery Disease.
- ultrasonography : Coronary Artery Disease.
- Aged, Female, Humans, Male, Middle Aged, Risk Factors, Time Factors, Treatment Outcome, Ultrasonography, Interventional.

Abstract

The aim of this study was to evaluate the impact of intravascular ultrasound (IVUS) guidance on the final volume of contrast agent used in patients undergoing percutaneous coronary intervention (PCI).

DOI: 10.1016/j.jcin.2014.05.024
PubMed: 25326742

Affiliations:

Links toward previous steps (curation, corpus...)

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Le document en format XML

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<author><name sortKey="Mariani, Jose" sort="Mariani, Jose" uniqKey="Mariani J" first="José" last="Mariani">José Mariani</name>
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<author><name sortKey="Spadaro, Andre G" sort="Spadaro, Andre G" uniqKey="Spadaro A" first="André G" last="Spadaro">André G. Spadaro</name>
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<author><name sortKey="Perin, Marco A" sort="Perin, Marco A" uniqKey="Perin M" first="Marco A" last="Perin">Marco A. Perin</name>
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<country xml:lang="fr">Brésil</country>
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<author><name sortKey="Filho, Antonio Esteves" sort="Filho, Antonio Esteves" uniqKey="Filho A" first="Antonio Esteves" last="Filho">Antonio Esteves Filho</name>
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<country xml:lang="fr">Brésil</country>
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<region type="state">État de São Paulo</region>
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<author><name sortKey="Takimura, Celso K" sort="Takimura, Celso K" uniqKey="Takimura C" first="Celso K" last="Takimura">Celso K. Takimura</name>
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<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
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<author><name sortKey="Ribeiro, Expedito" sort="Ribeiro, Expedito" uniqKey="Ribeiro E" first="Expedito" last="Ribeiro">Expedito Ribeiro</name>
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<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo</wicri:regionArea>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
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<author><name sortKey="Kalil Filho, Roberto" sort="Kalil Filho, Roberto" uniqKey="Kalil Filho R" first="Roberto" last="Kalil-Filho">Roberto Kalil-Filho</name>
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<region type="state">État de São Paulo</region>
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<author><name sortKey="Edelman, Elazer R" sort="Edelman, Elazer R" uniqKey="Edelman E" first="Elazer R" last="Edelman">Elazer R. Edelman</name>
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<author><name sortKey="Serruys, Patrick W" sort="Serruys, Patrick W" uniqKey="Serruys P" first="Patrick W" last="Serruys">Patrick W. Serruys</name>
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<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Thoraxcenter, Erasmus Medical Center, Rotterdam, the Netherlands; Imperial College London, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
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<author><name sortKey="Lemos, Pedro A" sort="Lemos, Pedro A" uniqKey="Lemos P" first="Pedro A" last="Lemos">Pedro A. Lemos</name>
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<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo</wicri:regionArea>
<placeName><settlement type="city">São Paulo</settlement>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention: the MOZART (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy) randomized controlled trial.</title>
<author><name sortKey="Mariani, Jose" sort="Mariani, Jose" uniqKey="Mariani J" first="José" last="Mariani">José Mariani</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo</wicri:regionArea>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Guedes, Cristiano" sort="Guedes, Cristiano" uniqKey="Guedes C" first="Cristiano" last="Guedes">Cristiano Guedes</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo</wicri:regionArea>
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<region type="state">État de São Paulo</region>
</placeName>
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<author><name sortKey="Soares, Paulo" sort="Soares, Paulo" uniqKey="Soares P" first="Paulo" last="Soares">Paulo Soares</name>
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<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo</wicri:regionArea>
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<author><name sortKey="Zalc, Silvio" sort="Zalc, Silvio" uniqKey="Zalc S" first="Silvio" last="Zalc">Silvio Zalc</name>
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<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo</wicri:regionArea>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
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<author><name sortKey="Campos, Carlos M" sort="Campos, Carlos M" uniqKey="Campos C" first="Carlos M" last="Campos">Carlos M. Campos</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo, Brazil; Thoraxcenter, Erasmus Medical Center, Rotterdam, the Netherlands.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo, Brazil; Thoraxcenter, Erasmus Medical Center, Rotterdam</wicri:regionArea>
<placeName><settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lopes, Augusto C" sort="Lopes, Augusto C" uniqKey="Lopes A" first="Augusto C" last="Lopes">Augusto C. Lopes</name>
<affiliation wicri:level="2"><nlm:affiliation>Institute of Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Institute of Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Spadaro, Andre G" sort="Spadaro, Andre G" uniqKey="Spadaro A" first="André G" last="Spadaro">André G. Spadaro</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo</wicri:regionArea>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Perin, Marco A" sort="Perin, Marco A" uniqKey="Perin M" first="Marco A" last="Perin">Marco A. Perin</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo</wicri:regionArea>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Filho, Antonio Esteves" sort="Filho, Antonio Esteves" uniqKey="Filho A" first="Antonio Esteves" last="Filho">Antonio Esteves Filho</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo</wicri:regionArea>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Takimura, Celso K" sort="Takimura, Celso K" uniqKey="Takimura C" first="Celso K" last="Takimura">Celso K. Takimura</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo</wicri:regionArea>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ribeiro, Expedito" sort="Ribeiro, Expedito" uniqKey="Ribeiro E" first="Expedito" last="Ribeiro">Expedito Ribeiro</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo</wicri:regionArea>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kalil Filho, Roberto" sort="Kalil Filho, Roberto" uniqKey="Kalil Filho R" first="Roberto" last="Kalil-Filho">Roberto Kalil-Filho</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo</wicri:regionArea>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Edelman, Elazer R" sort="Edelman, Elazer R" uniqKey="Edelman E" first="Elazer R" last="Edelman">Elazer R. Edelman</name>
<affiliation wicri:level="2"><nlm:affiliation>Institute of Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts; Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Institute of Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts; Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Serruys, Patrick W" sort="Serruys, Patrick W" uniqKey="Serruys P" first="Patrick W" last="Serruys">Patrick W. Serruys</name>
<affiliation wicri:level="3"><nlm:affiliation>Thoraxcenter, Erasmus Medical Center, Rotterdam, the Netherlands; Imperial College London, London, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Thoraxcenter, Erasmus Medical Center, Rotterdam, the Netherlands; Imperial College London, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lemos, Pedro A" sort="Lemos, Pedro A" uniqKey="Lemos P" first="Pedro A" last="Lemos">Pedro A. Lemos</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo, Brazil. Electronic address: pedro.lemos@incor.usp.br.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo</wicri:regionArea>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">JACC. Cardiovascular interventions</title>
<idno type="e-ISSN">1876-7605</idno>
<imprint><date when="2014" type="published">2014</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acute Kidney Injury (blood)</term>
<term>Acute Kidney Injury (chemically induced)</term>
<term>Acute Kidney Injury (diagnosis)</term>
<term>Acute Kidney Injury (prevention & control)</term>
<term>Aged</term>
<term>Biomarkers (blood)</term>
<term>Contrast Media (adverse effects)</term>
<term>Coronary Angiography (adverse effects)</term>
<term>Coronary Artery Disease (radiography)</term>
<term>Coronary Artery Disease (therapy)</term>
<term>Coronary Artery Disease (ultrasonography)</term>
<term>Creatinine (blood)</term>
<term>Female</term>
<term>Humans</term>
<term>Iohexol (adverse effects)</term>
<term>Iohexol (analogs & derivatives)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Percutaneous Coronary Intervention (adverse effects)</term>
<term>Percutaneous Coronary Intervention (methods)</term>
<term>Risk Factors</term>
<term>Time Factors</term>
<term>Treatment Outcome</term>
<term>Triiodobenzoic Acids (adverse effects)</term>
<term>Ultrasonography, Interventional</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Contrast Media</term>
<term>Iohexol</term>
<term>Triiodobenzoic Acids</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="analogs & derivatives" xml:lang="en"><term>Iohexol</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Biomarkers</term>
<term>Creatinine</term>
</keywords>
<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Coronary Angiography</term>
<term>Percutaneous Coronary Intervention</term>
</keywords>
<keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Acute Kidney Injury</term>
</keywords>
<keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Acute Kidney Injury</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Acute Kidney Injury</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Percutaneous Coronary Intervention</term>
</keywords>
<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Acute Kidney Injury</term>
</keywords>
<keywords scheme="MESH" qualifier="radiography" xml:lang="en"><term>Coronary Artery Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Coronary Artery Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="ultrasonography" xml:lang="en"><term>Coronary Artery Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Risk Factors</term>
<term>Time Factors</term>
<term>Treatment Outcome</term>
<term>Ultrasonography, Interventional</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The aim of this study was to evaluate the impact of intravascular ultrasound (IVUS) guidance on the final volume of contrast agent used in patients undergoing percutaneous coronary intervention (PCI).</div>
</front>
</TEI>
<pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">25326742</PMID>
<DateCreated><Year>2014</Year>
<Month>12</Month>
<Day>03</Day>
</DateCreated>
<DateCompleted><Year>2015</Year>
<Month>08</Month>
<Day>04</Day>
</DateCompleted>
<DateRevised><Year>2015</Year>
<Month>11</Month>
<Day>19</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1876-7605</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>7</Volume>
<Issue>11</Issue>
<PubDate><Year>2014</Year>
<Month>Nov</Month>
</PubDate>
</JournalIssue>
<Title>JACC. Cardiovascular interventions</Title>
<ISOAbbreviation>JACC Cardiovasc Interv</ISOAbbreviation>
</Journal>
<ArticleTitle>Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention: the MOZART (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy) randomized controlled trial.</ArticleTitle>
<Pagination><MedlinePgn>1287-93</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jcin.2014.05.024</ELocationID>
<ELocationID EIdType="pii" ValidYN="Y">S1936-8798(14)01236-9</ELocationID>
<Abstract><AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">The aim of this study was to evaluate the impact of intravascular ultrasound (IVUS) guidance on the final volume of contrast agent used in patients undergoing percutaneous coronary intervention (PCI).</AbstractText>
<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">To date, few approaches have been described to reduce the final dose of contrast agent in PCIs. We hypothesized that IVUS might serve as an alternative imaging tool to angiography in many steps during PCI, thereby reducing the use of iodine contrast.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">A total of 83 patients were randomized to angiography-guided PCI or IVUS-guided PCI; both groups were treated according to a pre-defined meticulous procedural strategy. The primary endpoint was the total volume contrast agent used during PCI. Patients were followed clinically for an average of 4 months.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The median total volume of contrast was 64.5 ml (interquartile range [IQR]: 42.8 to 97.0 ml; minimum, 19 ml; maximum, 170 ml) in the angiography-guided group versus 20.0 ml (IQR: 12.5 to 30.0 ml; minimum, 3 ml; maximum, 54 ml) in the IVUS-guided group (p < 0.001). Similarly, the median volume of contrast/creatinine clearance ratio was significantly lower among patients treated with IVUS-guided PCI (1.0 [IQR: 0.6 to 1.9] vs. 0.4 [IQR: 0.2 to 0.6, respectively; p < 0.001). In-hospital and 4-month outcomes were not different between patients randomized to angiography-guided and IVUS-guided PCI.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Thoughtful and extensive use of IVUS as the primary imaging tool to guide PCI is safe and markedly reduces the volume of iodine contrast compared with angiography-alone guidance. The use of IVUS should be considered for patients at high risk of contrast-induced acute kidney injury or volume overload undergoing coronary angioplasty. (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy [MOZART]; NCT01947335).</AbstractText>
<CopyrightInformation>Copyright © 2014 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Mariani</LastName>
<ForeName>José</ForeName>
<Initials>J</Initials>
<Suffix>Jr</Suffix>
<AffiliationInfo><Affiliation>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Guedes</LastName>
<ForeName>Cristiano</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Soares</LastName>
<ForeName>Paulo</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zalc</LastName>
<ForeName>Silvio</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Campos</LastName>
<ForeName>Carlos M</ForeName>
<Initials>CM</Initials>
<AffiliationInfo><Affiliation>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo, Brazil; Thoraxcenter, Erasmus Medical Center, Rotterdam, the Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lopes</LastName>
<ForeName>Augusto C</ForeName>
<Initials>AC</Initials>
<AffiliationInfo><Affiliation>Institute of Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Spadaro</LastName>
<ForeName>André G</ForeName>
<Initials>AG</Initials>
<AffiliationInfo><Affiliation>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Perin</LastName>
<ForeName>Marco A</ForeName>
<Initials>MA</Initials>
<AffiliationInfo><Affiliation>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Filho</LastName>
<ForeName>Antonio Esteves</ForeName>
<Initials>AE</Initials>
<AffiliationInfo><Affiliation>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Takimura</LastName>
<ForeName>Celso K</ForeName>
<Initials>CK</Initials>
<AffiliationInfo><Affiliation>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ribeiro</LastName>
<ForeName>Expedito</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kalil-Filho</LastName>
<ForeName>Roberto</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Edelman</LastName>
<ForeName>Elazer R</ForeName>
<Initials>ER</Initials>
<AffiliationInfo><Affiliation>Institute of Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts; Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Serruys</LastName>
<ForeName>Patrick W</ForeName>
<Initials>PW</Initials>
<AffiliationInfo><Affiliation>Thoraxcenter, Erasmus Medical Center, Rotterdam, the Netherlands; Imperial College London, London, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lemos</LastName>
<ForeName>Pedro A</ForeName>
<Initials>PA</Initials>
<AffiliationInfo><Affiliation>Department of Interventional Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Sao Paulo, Brazil. Electronic address: pedro.lemos@incor.usp.br.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<DataBankList CompleteYN="Y"><DataBank><DataBankName>ClinicalTrials.gov</DataBankName>
<AccessionNumberList><AccessionNumber>NCT01947335</AccessionNumber>
</AccessionNumberList>
</DataBank>
</DataBankList>
<GrantList CompleteYN="Y"><Grant><GrantID>R01 GM049039</GrantID>
<Acronym>GM</Acronym>
<Agency>NIGMS NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant><GrantID>R01 GM49039</GrantID>
<Acronym>GM</Acronym>
<Agency>NIGMS NIH HHS</Agency>
<Country>United States</Country>
</Grant>
</GrantList>
<PublicationTypeList><PublicationType UI="D003160">Comparative Study</PublicationType>
<PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D016449">Randomized Controlled Trial</PublicationType>
<PublicationType UI="D052061">Research Support, N.I.H., Extramural</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2014</Year>
<Month>10</Month>
<Day>15</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>JACC Cardiovasc Interv</MedlineTA>
<NlmUniqueID>101467004</NlmUniqueID>
<ISSNLinking>1936-8798</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D015415">Biomarkers</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D003287">Contrast Media</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D014283">Triiodobenzoic Acids</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>4419T9MX03</RegistryNumber>
<NameOfSubstance UI="D007472">Iohexol</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>712BAC33MZ</RegistryNumber>
<NameOfSubstance UI="C038192">iopromide</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>92339-11-2</RegistryNumber>
<NameOfSubstance UI="C044834">iodixanol</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>AYI8EX34EU</RegistryNumber>
<NameOfSubstance UI="D003404">Creatinine</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>JACC Cardiovasc Interv. 2014 Nov;7(11):1294-6</RefSource>
<PMID Version="1">25459042</PMID>
</CommentsCorrections>
</CommentsCorrectionsList>
<MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D058186">Acute Kidney Injury</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000097">blood</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000139">chemically induced</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000175">diagnosis</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000517">prevention & control</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D015415">Biomarkers</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000097">blood</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="Y" UI="D003287">Contrast Media</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000009">adverse effects</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="Y" UI="D017023">Coronary Angiography</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000009">adverse effects</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D003324">Coronary Artery Disease</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000530">radiography</QualifierName>
<QualifierName MajorTopicYN="Y" UI="Q000628">therapy</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000736">ultrasonography</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D003404">Creatinine</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000097">blood</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D007472">Iohexol</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000009">adverse effects</QualifierName>
<QualifierName MajorTopicYN="Y" UI="Q000031">analogs & derivatives</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D062645">Percutaneous Coronary Intervention</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000009">adverse effects</QualifierName>
<QualifierName MajorTopicYN="Y" UI="Q000379">methods</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D012307">Risk Factors</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D013997">Time Factors</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D016896">Treatment Outcome</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="Y" UI="D014283">Triiodobenzoic Acids</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000009">adverse effects</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="Y" UI="D018084">Ultrasonography, Interventional</DescriptorName>
</MeshHeading>
</MeshHeadingList>
<OtherID Source="NLM">NIHMS733770</OtherID>
<OtherID Source="NLM">PMC4637944</OtherID>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">contrast</Keyword>
<Keyword MajorTopicYN="N">coronary intravascular ultrasound</Keyword>
<Keyword MajorTopicYN="N">renal failure</Keyword>
<Keyword MajorTopicYN="N">stent</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2013</Year>
<Month>12</Month>
<Day>17</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="revised"><Year>2014</Year>
<Month>4</Month>
<Day>25</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2014</Year>
<Month>5</Month>
<Day>22</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="aheadofprint"><Year>2014</Year>
<Month>10</Month>
<Day>15</Day>
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<Month>10</Month>
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<Hour>6</Hour>
<Minute>0</Minute>
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<PubMedPubDate PubStatus="medline"><Year>2015</Year>
<Month>8</Month>
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<PublicationStatus>ppublish</PublicationStatus>
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<ArticleId IdType="doi">10.1016/j.jcin.2014.05.024</ArticleId>
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<affiliations><list><country><li>Brésil</li>
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<li>Royaume-Uni</li>
<li>États-Unis</li>
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<region><li>Angleterre</li>
<li>Grand Londres</li>
<li>Hollande-Méridionale</li>
<li>Massachusetts</li>
<li>État de São Paulo</li>
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<tree><country name="Brésil"><region name="État de São Paulo"><name sortKey="Mariani, Jose" sort="Mariani, Jose" uniqKey="Mariani J" first="José" last="Mariani">José Mariani</name>
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<name sortKey="Filho, Antonio Esteves" sort="Filho, Antonio Esteves" uniqKey="Filho A" first="Antonio Esteves" last="Filho">Antonio Esteves Filho</name>
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<name sortKey="Kalil Filho, Roberto" sort="Kalil Filho, Roberto" uniqKey="Kalil Filho R" first="Roberto" last="Kalil-Filho">Roberto Kalil-Filho</name>
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<name sortKey="Perin, Marco A" sort="Perin, Marco A" uniqKey="Perin M" first="Marco A" last="Perin">Marco A. Perin</name>
<name sortKey="Ribeiro, Expedito" sort="Ribeiro, Expedito" uniqKey="Ribeiro E" first="Expedito" last="Ribeiro">Expedito Ribeiro</name>
<name sortKey="Soares, Paulo" sort="Soares, Paulo" uniqKey="Soares P" first="Paulo" last="Soares">Paulo Soares</name>
<name sortKey="Spadaro, Andre G" sort="Spadaro, Andre G" uniqKey="Spadaro A" first="André G" last="Spadaro">André G. Spadaro</name>
<name sortKey="Takimura, Celso K" sort="Takimura, Celso K" uniqKey="Takimura C" first="Celso K" last="Takimura">Celso K. Takimura</name>
<name sortKey="Zalc, Silvio" sort="Zalc, Silvio" uniqKey="Zalc S" first="Silvio" last="Zalc">Silvio Zalc</name>
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<country name="Pays-Bas"><region name="Hollande-Méridionale"><name sortKey="Campos, Carlos M" sort="Campos, Carlos M" uniqKey="Campos C" first="Carlos M" last="Campos">Carlos M. Campos</name>
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</country>
<country name="États-Unis"><region name="Massachusetts"><name sortKey="Lopes, Augusto C" sort="Lopes, Augusto C" uniqKey="Lopes A" first="Augusto C" last="Lopes">Augusto C. Lopes</name>
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</country>
<country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Serruys, Patrick W" sort="Serruys, Patrick W" uniqKey="Serruys P" first="Patrick W" last="Serruys">Patrick W. Serruys</name>
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Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention: the MOZART (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy) randomized controlled trial.

Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention: the MOZART (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy) randomized controlled trial.

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