Mzt1/Tam4, a fission yeast MOZART1 homologue, is an essential component of the γ-tubulin complex and directly interacts with GCP3Alp6
Identifieur interne : 000762 ( Pmc/Corpus ); précédent : 000761; suivant : 000763Mzt1/Tam4, a fission yeast MOZART1 homologue, is an essential component of the γ-tubulin complex and directly interacts with GCP3Alp6
Auteurs : Deepsharan K. Dhani ; Benjamin T. Goult ; Gifty M. George ; Daniel T. Rogerson ; Danny A. Bitton ; Crispin J. Miller ; John W. R. Schwabe ; Kayoko TanakaSource :
- Molecular Biology of the Cell [ 1059-1524 ] ; 2013.
Abstract
Fission yeast MOZART1 homologue Mzt1 associates with γ-tubulin and is found at MTOCs. It plays an essential role in microtubule regulation, as well as in septum formation and cytokinesis. Recombinant Mzt1 interacts directly with GCP3Alp6. This interaction may assist MTOC activity of the γ-tubulin complex.
Url:
DOI: 10.1091/mbc.E13-05-0253
PubMed: 24006493
PubMed Central: 3814152
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