Mozart K.545 Mimics Mozart K.448 in Reducing Epileptiform Discharges in Epileptic Children
Identifieur interne : 000411 ( Main/Exploration ); précédent : 000410; suivant : 000412Mozart K.545 Mimics Mozart K.448 in Reducing Epileptiform Discharges in Epileptic Children
Auteurs : Lung-Chang Lin [Taïwan] ; Mei-Wen Lee [Taïwan] ; Ruey-Chang Wei [Taïwan] ; Hin-Kiu Mok [Taïwan] ; Hui-Chuan Wu [Taïwan] ; Chin-Lin Tsai [Taïwan] ; Rei-Cheng Yang [Taïwan]Source :
- Evidence-based Complementary and Alternative Medicine : eCAM [ 1741-427X ] ; 2012.
Abstract
Mozart K.448 has been shown to improve cognitive function, leading to what is known as the Mozart Effect. Our previous work reveals positive effects of Mozart K.448 in reducing epileptiform discharges in epileptic children. In this study, we evaluated the effect of Mozart K.545 and compared the effects with those of Mozart K.448 on epileptiform discharges in children with epilepsy. Thirty-nine epileptic children with epileptiform discharges were included in the study. They received electroencephalogram examinations before, during, and after listening to Mozart K.448 and K.545, one week apart, respectively. The frequencies of epileptiform discharges were compared. There was a significant decrease in the frequency of epileptiform discharges during and right after listening to Mozart K.448 and K.545 (reduced by 35.7 ± 32.7% during Mozart K.448 and 30.3 ± 44.4% after Mozart K.448; and 34.0 ± 39.5% during Mozart K.545 and 31.8 ± 39.2% after Mozart K.545). Spectrogrammatic analysis of the two pieces of music demonstrated that both share similar spectrogrammatic characteristics. Listening to Mozart K.448 and K.545 decreased the epileptiform discharges in epileptic children. This suggests that Mozart K.448 is not the only piece of music to have beneficial effects on children with epilepsy. Other music with lower harmonics may also decrease epileptiform discharges in epileptic children.
Url:
DOI: 10.1155/2012/607517
PubMed: 23304207
PubMed Central: 3523174
Affiliations:
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Kaohsiung City 807, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Pediatrics, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung City 807</wicri:regionArea><wicri:noRegion>Kaohsiung City 807</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="I2">Department of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung City 807, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung City 807</wicri:regionArea><wicri:noRegion>Kaohsiung City 807</wicri:noRegion></affiliation></author><author><name sortKey="Lee, Mei Wen" sort="Lee, Mei Wen" uniqKey="Lee M" first="Mei-Wen" last="Lee">Mei-Wen Lee</name><affiliation wicri:level="1"><nlm:aff id="I3">Department of Music, National Sun Yat-Sen University, Kaohsiung City 804, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Music, National Sun Yat-Sen University, Kaohsiung City 804</wicri:regionArea><wicri:noRegion>Kaohsiung City 804</wicri:noRegion></affiliation></author><author><name sortKey="Wei, Ruey Chang" sort="Wei, Ruey Chang" uniqKey="Wei R" first="Ruey-Chang" last="Wei">Ruey-Chang Wei</name><affiliation wicri:level="1"><nlm:aff id="I4">Institute of Applied Physics and Underseas Technology, National Sun Yat-Sen University, Kaohsiung City 804, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Institute of Applied Physics and Underseas Technology, National Sun Yat-Sen University, Kaohsiung City 804</wicri:regionArea><wicri:noRegion>Kaohsiung City 804</wicri:noRegion></affiliation></author><author><name sortKey="Mok, Hin Kiu" sort="Mok, Hin Kiu" uniqKey="Mok H" first="Hin-Kiu" last="Mok">Hin-Kiu Mok</name><affiliation wicri:level="1"><nlm:aff id="I5">Institute of Marine Biology, National Sun Yat-Sen University, Kaohsiung City 804, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Institute of Marine Biology, National Sun Yat-Sen University, Kaohsiung City 804</wicri:regionArea><wicri:noRegion>Kaohsiung City 804</wicri:noRegion></affiliation></author><author><name sortKey="Wu, Hui Chuan" sort="Wu, Hui Chuan" uniqKey="Wu H" first="Hui-Chuan" last="Wu">Hui-Chuan Wu</name><affiliation wicri:level="1"><nlm:aff id="I2">Department of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung City 807, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung City 807</wicri:regionArea><wicri:noRegion>Kaohsiung City 807</wicri:noRegion></affiliation></author><author><name sortKey="Tsai, Chin Lin" sort="Tsai, Chin Lin" uniqKey="Tsai C" first="Chin-Lin" last="Tsai">Chin-Lin Tsai</name><affiliation wicri:level="1"><nlm:aff id="I6">Department of Neurology, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung Medical University, Kaohsiung City 807, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Neurology, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung Medical University, Kaohsiung City 807</wicri:regionArea><wicri:noRegion>Kaohsiung City 807</wicri:noRegion></affiliation></author><author><name sortKey="Yang, Rei Cheng" sort="Yang, Rei Cheng" uniqKey="Yang R" first="Rei-Cheng" last="Yang">Rei-Cheng Yang</name><affiliation wicri:level="1"><nlm:aff id="I2">Department of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung City 807, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung City 807</wicri:regionArea><wicri:noRegion>Kaohsiung City 807</wicri:noRegion></affiliation></author></analytic><series><title level="j">Evidence-based Complementary and Alternative Medicine : eCAM</title><idno type="ISSN">1741-427X</idno><idno type="e-ISSN">1741-4288</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Mozart K.448 has been shown to improve cognitive function, leading to what is known as the Mozart Effect. Our previous work reveals positive effects of Mozart K.448 in reducing epileptiform discharges in epileptic children. In this study, we evaluated the effect of Mozart K.545 and compared the effects with those of Mozart K.448 on epileptiform discharges in children with epilepsy. Thirty-nine epileptic children with epileptiform discharges were included in the study. They received electroencephalogram examinations before, during, and after listening to Mozart K.448 and K.545, one week apart, respectively. The frequencies of epileptiform discharges were compared. There was a significant decrease in the frequency of epileptiform discharges during and right after listening to Mozart K.448 and K.545 (reduced by 35.7 ± 32.7% during Mozart K.448 and 30.3 ± 44.4% after Mozart K.448; and 34.0 ± 39.5% during Mozart K.545 and 31.8 ± 39.2% after Mozart K.545). Spectrogrammatic analysis of the two pieces of music demonstrated that both share similar spectrogrammatic characteristics. Listening to Mozart K.448 and K.545 decreased the epileptiform discharges in epileptic children. This suggests that Mozart K.448 is not the only piece of music to have beneficial effects on children with epilepsy. Other music with lower harmonics may also decrease epileptiform discharges in epileptic children.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Rauscher, Fh" uniqKey="Rauscher F">FH Rauscher</name></author><author><name sortKey="Shaw, Gl" uniqKey="Shaw G">GL Shaw</name></author><author><name sortKey="Ky, Kn" uniqKey="Ky K">KN Ky</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pacchetti, C" uniqKey="Pacchetti C">C Pacchetti</name></author><author><name sortKey="Mancini, F" uniqKey="Mancini F">F Mancini</name></author><author><name sortKey="Aglieri, R" uniqKey="Aglieri R">R Aglieri</name></author><author><name sortKey="Fundar, C" uniqKey="Fundar C">C Fundaró</name></author><author><name sortKey="Martignoni, E" uniqKey="Martignoni E">E Martignoni</name></author><author><name sortKey="Nappi, G" uniqKey="Nappi G">G Nappi</name></author></analytic></biblStruct><biblStruct><analytic><author><name 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Fonteles</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Taïwan</li></country></list><tree><country name="Taïwan"><noRegion><name sortKey="Lin, Lung Chang" sort="Lin, Lung Chang" uniqKey="Lin L" first="Lung-Chang" last="Lin">Lung-Chang Lin</name></noRegion><name sortKey="Lee, Mei Wen" sort="Lee, Mei Wen" uniqKey="Lee M" first="Mei-Wen" last="Lee">Mei-Wen Lee</name><name sortKey="Lin, Lung Chang" sort="Lin, Lung Chang" uniqKey="Lin L" first="Lung-Chang" last="Lin">Lung-Chang Lin</name><name sortKey="Mok, Hin Kiu" sort="Mok, Hin Kiu" uniqKey="Mok H" first="Hin-Kiu" last="Mok">Hin-Kiu Mok</name><name sortKey="Tsai, Chin Lin" sort="Tsai, Chin Lin" uniqKey="Tsai C" first="Chin-Lin" last="Tsai">Chin-Lin Tsai</name><name sortKey="Wei, Ruey Chang" sort="Wei, Ruey Chang" uniqKey="Wei R" first="Ruey-Chang" last="Wei">Ruey-Chang Wei</name><name sortKey="Wu, Hui Chuan" sort="Wu, Hui Chuan" uniqKey="Wu H" first="Hui-Chuan" last="Wu">Hui-Chuan Wu</name><name sortKey="Yang, Rei Cheng" sort="Yang, Rei Cheng" uniqKey="Yang R" first="Rei-Cheng" last="Yang">Rei-Cheng Yang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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