Ibuprofen in Experimental Vascular Surgery
Identifieur interne : 000B07 ( Main/Exploration ); précédent : 000B06; suivant : 000B08Ibuprofen in Experimental Vascular Surgery
Auteurs : Michael P. Kaye [États-Unis] ; Peter Gloviczki [États-Unis] ; Mrinal K. Dewanjee [États-Unis] ; Paul L. Claus [États-Unis] ; Mark E. Lovaas [États-Unis]Source :
- The American Journal of Medicine [ 0002-9343 ] ; 1984.
Abstract
Animal studies have been conducted to determine the effectiveness of ibuprofen in reducing early platelet deposition on small diameter (4 mm) Gore-Tex (polytetrafluoroethylene) arterial grafts and larger (10 mm) Gore-Tex grafts placed in the inferior vena cava. These studies demonstrated a significant reduction ln platelet deposition at one and three hours. Additional studies of animals undergoing treatment with ibuprofen and subjected to arterial replacement with 1 or 4 mm Gore-Tex grafts demonstrated enhanced patency at 30 days. Cautious evaluation of Ibuprofen as an adjunct in vascular surgery appears warranted.
Url:
DOI: 10.1016/S0002-9343(84)80026-1
Affiliations:
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<front><div type="abstract">Animal studies have been conducted to determine the effectiveness of ibuprofen in reducing early platelet deposition on small diameter (4 mm) Gore-Tex (polytetrafluoroethylene) arterial grafts and larger (10 mm) Gore-Tex grafts placed in the inferior vena cava. These studies demonstrated a significant reduction ln platelet deposition at one and three hours. Additional studies of animals undergoing treatment with ibuprofen and subjected to arterial replacement with 1 or 4 mm Gore-Tex grafts demonstrated enhanced patency at 30 days. Cautious evaluation of Ibuprofen as an adjunct in vascular surgery appears warranted.</div>
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