Hepatotoxic effect of cortisone in experimental animals
Identifieur interne : 000544 ( Istex/Corpus ); précédent : 000543; suivant : 000545Hepatotoxic effect of cortisone in experimental animals
Auteurs : H. Tanyol ; Martin E. RehfussSource :
- The American Journal of Digestive Diseases [ 0002-9211 ] ; 1955-06-01.
Abstract
Summary: 1. A quantitative cytological approach in the comparative study of liver damage is described. 2. Varying degrees of hepatocellular degeneration and necrosis were found in animals treated with cortisone in maximal doses. 3. The hepatotoxic effects of carbon tetrachloride poisoning were augmented, and not reduced, by concomitant treatment with cortisone. 4. The rationale of therapy with cortisone in human cases of liver disease is discussed.
Url:
DOI: 10.1007/BF02886003
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Rehfuss</name><affiliation><mods:affiliation>Deperment of Medicine of the Jefferson Medical College, Philadelphi, Pa.</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:3416E4E1029E608115801CCC7EFFAA24BB93104C</idno><date when="1954" year="1954">1954</date><idno type="doi">10.1007/BF02886003</idno><idno type="url">https://api.istex.fr/document/3416E4E1029E608115801CCC7EFFAA24BB93104C/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000544</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000544</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Hepatotoxic effect of cortisone in experimental animals</title><author><name sortKey="Tanyol, H" sort="Tanyol, H" uniqKey="Tanyol H" first="H." last="Tanyol">H. Tanyol</name><affiliation><mods:affiliation>Deperment of Medicine of the Jefferson Medical College, Philadelphi, Pa.</mods:affiliation></affiliation></author><author><name sortKey="Rehfuss, Martin E" sort="Rehfuss, Martin E" uniqKey="Rehfuss M" first="Martin E." last="Rehfuss">Martin E. Rehfuss</name><affiliation><mods:affiliation>Deperment of Medicine of the Jefferson Medical College, Philadelphi, Pa.</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">The American Journal of Digestive Diseases</title><title level="j" type="abbrev">Amer. Jour. Dig. 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Varying degrees of hepatocellular degeneration and necrosis were found in animals treated with cortisone in maximal doses. 3. The hepatotoxic effects of carbon tetrachloride poisoning were augmented, and not reduced, by concomitant treatment with cortisone. 4. The rationale of therapy with cortisone in human cases of liver disease is discussed.</div></front></TEI><istex><corpusName>springer</corpusName><author><json:item><name>H. Tanyol</name><affiliations><json:string>Deperment of Medicine of the Jefferson Medical College, Philadelphi, Pa.</json:string></affiliations></json:item><json:item><name>Martin E. Rehfuss</name><affiliations><json:string>Deperment of Medicine of the Jefferson Medical College, Philadelphi, Pa.</json:string></affiliations></json:item></author><articleId><json:string>Art3</json:string><json:string>BF02886003</json:string></articleId><language><json:string>eng</json:string></language><abstract>Summary: 1. A quantitative cytological approach in the comparative study of liver damage is described. 2. Varying degrees of hepatocellular degeneration and necrosis were found in animals treated with cortisone in maximal doses. 3. The hepatotoxic effects of carbon tetrachloride poisoning were augmented, and not reduced, by concomitant treatment with cortisone. 4. 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