TWO MALE SIBLINGs' CASES OF SPECIFIC LIPIDOSIS FOUND BY ELECTRON MICROSCOPY
Identifieur interne : 000434 ( Istex/Corpus ); précédent : 000433; suivant : 000435TWO MALE SIBLINGs' CASES OF SPECIFIC LIPIDOSIS FOUND BY ELECTRON MICROSCOPY
Auteurs : Kunitaro Yamaguchi ; Hideo Tsuchiyama ; Kimiko TabataSource :
- Pathology International [ 1320-5463 ] ; 1971-08.
Abstract
Biopsy materials obtained from cervical lymph nodes and liver tissues of two male siblings, 5 years and 10 months old and 1 year and 11 months old, were studied electron microscopically. The results were summarized as follows: 1) Marked accumulation of lipid droplets, probably neutral fat, and cholesterol clefts in reticulum cells of lymph node, Kupffer cells and hepatic cells was the most prominent feature in these biopsies. 2) These lipids were found in both lysosomes and cytoplasmic matrices. Many of the lysosomes were considered to be autolysosomes or autophagosomes, because they contained fibrillar components, endoplasmic reticulum, glycogen particles and degraded organelles. It was suggested that these lipids might have been synthesized in lysosomes. 3) This disorder seems not to be included in the category of inborn lysosomal disease, and is considered as an unclassified one.
Url:
DOI: 10.1111/j.1440-1827.1971.tb00135.x
Links to Exploration step
ISTEX:08483FEE118B35885C12946CC4209F817DDEC0F2Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">TWO MALE SIBLINGs' CASES OF SPECIFIC LIPIDOSIS FOUND BY ELECTRON MICROSCOPY</title><author><name sortKey="Yamaguchi, Kunitaro" sort="Yamaguchi, Kunitaro" uniqKey="Yamaguchi K" first="Kunitaro" last="Yamaguchi">Kunitaro Yamaguchi</name><affiliation><mods:affiliation>*Department of Pathology, Faculty of Medicine, Nagasaki University, Nagasaki</mods:affiliation></affiliation></author><author><name sortKey="Tsuchiyama, Hideo" sort="Tsuchiyama, Hideo" uniqKey="Tsuchiyama H" first="Hideo" last="Tsuchiyama">Hideo Tsuchiyama</name><affiliation><mods:affiliation>*Department of Pathology, Faculty of Medicine, Nagasaki University, Nagasaki</mods:affiliation></affiliation></author><author><name sortKey="Tabata, Kimiko" sort="Tabata, Kimiko" uniqKey="Tabata K" first="Kimiko" last="Tabata">Kimiko Tabata</name><affiliation><mods:affiliation>**Department of Pediatrics, Omura Prefectural Hospital, Omura</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:08483FEE118B35885C12946CC4209F817DDEC0F2</idno><date when="1971" year="1971">1971</date><idno type="doi">10.1111/j.1440-1827.1971.tb00135.x</idno><idno type="url">https://api.istex.fr/document/08483FEE118B35885C12946CC4209F817DDEC0F2/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000434</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000434</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">TWO MALE SIBLINGs' CASES OF SPECIFIC LIPIDOSIS FOUND BY ELECTRON MICROSCOPY</title><author><name sortKey="Yamaguchi, Kunitaro" sort="Yamaguchi, Kunitaro" uniqKey="Yamaguchi K" first="Kunitaro" last="Yamaguchi">Kunitaro Yamaguchi</name><affiliation><mods:affiliation>*Department of Pathology, Faculty of Medicine, Nagasaki University, Nagasaki</mods:affiliation></affiliation></author><author><name sortKey="Tsuchiyama, Hideo" sort="Tsuchiyama, Hideo" uniqKey="Tsuchiyama H" first="Hideo" last="Tsuchiyama">Hideo Tsuchiyama</name><affiliation><mods:affiliation>*Department of Pathology, Faculty of Medicine, Nagasaki University, Nagasaki</mods:affiliation></affiliation></author><author><name sortKey="Tabata, Kimiko" sort="Tabata, Kimiko" uniqKey="Tabata K" first="Kimiko" last="Tabata">Kimiko Tabata</name><affiliation><mods:affiliation>**Department of Pediatrics, Omura Prefectural Hospital, Omura</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Pathology International</title><idno type="ISSN">1320-5463</idno><idno type="eISSN">1440-1827</idno><imprint><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="1971-08">1971-08</date><biblScope unit="volume">21</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="445">445</biblScope><biblScope unit="page" to="458">458</biblScope></imprint><idno type="ISSN">1320-5463</idno></series><idno type="istex">08483FEE118B35885C12946CC4209F817DDEC0F2</idno><idno type="DOI">10.1111/j.1440-1827.1971.tb00135.x</idno><idno type="ArticleID">PIN445</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1320-5463</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Biopsy materials obtained from cervical lymph nodes and liver tissues of two male siblings, 5 years and 10 months old and 1 year and 11 months old, were studied electron microscopically. The results were summarized as follows: 1) Marked accumulation of lipid droplets, probably neutral fat, and cholesterol clefts in reticulum cells of lymph node, Kupffer cells and hepatic cells was the most prominent feature in these biopsies. 2) These lipids were found in both lysosomes and cytoplasmic matrices. Many of the lysosomes were considered to be autolysosomes or autophagosomes, because they contained fibrillar components, endoplasmic reticulum, glycogen particles and degraded organelles. It was suggested that these lipids might have been synthesized in lysosomes. 3) This disorder seems not to be included in the category of inborn lysosomal disease, and is considered as an unclassified one.</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Kunitaro Yamaguchi</name><affiliations><json:string>*Department of Pathology, Faculty of Medicine, Nagasaki University, Nagasaki</json:string></affiliations></json:item><json:item><name>Hideo Tsuchiyama</name><affiliations><json:string>*Department of Pathology, Faculty of Medicine, Nagasaki University, Nagasaki</json:string></affiliations></json:item><json:item><name>Kimiko Tabata</name><affiliations><json:string>**Department of Pediatrics, Omura Prefectural Hospital, Omura</json:string></affiliations></json:item></author><articleId><json:string>PIN445</json:string></articleId><language><json:string>eng</json:string></language><abstract>Biopsy materials obtained from cervical lymph nodes and liver tissues of two male siblings, 5 years and 10 months old and 1 year and 11 months old, were studied electron microscopically. The results were summarized as follows: 1) Marked accumulation of lipid droplets, probably neutral fat, and cholesterol clefts in reticulum cells of lymph node, Kupffer cells and hepatic cells was the most prominent feature in these biopsies. 2) These lipids were found in both lysosomes and cytoplasmic matrices. Many of the lysosomes were considered to be autolysosomes or autophagosomes, because they contained fibrillar components, endoplasmic reticulum, glycogen particles and degraded organelles. It was suggested that these lipids might have been synthesized in lysosomes. 3) This disorder seems not to be included in the category of inborn lysosomal disease, and is considered as an unclassified one.</abstract><qualityIndicators><score>4.525</score><pdfVersion>1.3</pdfVersion><pdfPageSize>506.88 x 733.679 pts</pdfPageSize><refBibsNative>true</refBibsNative><keywordCount>0</keywordCount><abstractCharCount>895</abstractCharCount><pdfWordCount>2893</pdfWordCount><pdfCharCount>18172</pdfCharCount><pdfPageCount>14</pdfPageCount><abstractWordCount>136</abstractWordCount></qualityIndicators><title>TWO MALE SIBLINGs' CASES OF SPECIFIC LIPIDOSIS FOUND BY ELECTRON MICROSCOPY</title><genre><json:string>article</json:string></genre><host><volume>21</volume><publisherId><json:string>PIN</json:string></publisherId><pages><total>14</total><last>458</last><first>445</first></pages><issn><json:string>1320-5463</json:string></issn><issue>3</issue><genre><json:string>Journal</json:string></genre><language><json:string>unknown</json:string></language><eissn><json:string>1440-1827</json:string></eissn><title>Pathology International</title><doi><json:string>10.1111/(ISSN)1440-1827</json:string></doi></host><publicationDate>1971</publicationDate><copyrightDate>1971</copyrightDate><doi><json:string>10.1111/j.1440-1827.1971.tb00135.x</json:string></doi><id>08483FEE118B35885C12946CC4209F817DDEC0F2</id><fulltext><json:item><original>true</original><mimetype>application/pdf</mimetype><extension>pdf</extension><uri>https://api.istex.fr/document/08483FEE118B35885C12946CC4209F817DDEC0F2/fulltext/pdf</uri></json:item><json:item><original>false</original><mimetype>application/zip</mimetype><extension>zip</extension><uri>https://api.istex.fr/document/08483FEE118B35885C12946CC4209F817DDEC0F2/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/08483FEE118B35885C12946CC4209F817DDEC0F2/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">TWO MALE SIBLINGs' CASES OF SPECIFIC LIPIDOSIS FOUND BY ELECTRON MICROSCOPY</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><availability><p>WILEY</p></availability><date>1971</date></publicationStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">TWO MALE SIBLINGs' CASES OF SPECIFIC LIPIDOSIS FOUND BY ELECTRON MICROSCOPY</title><author><persName><forename type="first">Kunitaro</forename><surname>Yamaguchi</surname></persName><affiliation>*Department of Pathology, Faculty of Medicine, Nagasaki University, Nagasaki</affiliation></author><author><persName><forename type="first">Hideo</forename><surname>Tsuchiyama</surname></persName><affiliation>*Department of Pathology, Faculty of Medicine, Nagasaki University, Nagasaki</affiliation></author><author><persName><forename type="first">Kimiko</forename><surname>Tabata</surname></persName><affiliation>**Department of Pediatrics, Omura Prefectural Hospital, Omura</affiliation></author></analytic><monogr><title level="j">Pathology International</title><idno type="pISSN">1320-5463</idno><idno type="eISSN">1440-1827</idno><idno type="DOI">10.1111/(ISSN)1440-1827</idno><imprint><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="1971-08"></date><biblScope unit="volume">21</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="445">445</biblScope><biblScope unit="page" to="458">458</biblScope></imprint></monogr><idno type="istex">08483FEE118B35885C12946CC4209F817DDEC0F2</idno><idno type="DOI">10.1111/j.1440-1827.1971.tb00135.x</idno><idno type="ArticleID">PIN445</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>1971</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Biopsy materials obtained from cervical lymph nodes and liver tissues of two male siblings, 5 years and 10 months old and 1 year and 11 months old, were studied electron microscopically. The results were summarized as follows: 1) Marked accumulation of lipid droplets, probably neutral fat, and cholesterol clefts in reticulum cells of lymph node, Kupffer cells and hepatic cells was the most prominent feature in these biopsies. 2) These lipids were found in both lysosomes and cytoplasmic matrices. Many of the lysosomes were considered to be autolysosomes or autophagosomes, because they contained fibrillar components, endoplasmic reticulum, glycogen particles and degraded organelles. It was suggested that these lipids might have been synthesized in lysosomes. 3) This disorder seems not to be included in the category of inborn lysosomal disease, and is considered as an unclassified one.</p></abstract></profileDesc><revisionDesc><change when="1971-08">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/08483FEE118B35885C12946CC4209F817DDEC0F2/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Blackwell Publishing Ltd</publisherName><publisherLoc>Oxford, UK</publisherLoc></publisherInfo><doi origin="wiley" registered="yes">10.1111/(ISSN)1440-1827</doi><issn type="print">1320-5463</issn><issn type="electronic">1440-1827</issn><idGroup><id type="product" value="PIN"></id><id type="publisherDivision" value="ST"></id></idGroup><titleGroup><title type="main" sort="PATHOLOGY INTERNATIONAL">Pathology International</title></titleGroup></publicationMeta><publicationMeta level="part" position="08003"><doi origin="wiley">10.1111/pin.1971.21.issue-3</doi><numberingGroup><numbering type="journalVolume" number="21">21</numbering><numbering type="journalIssue" number="3">3</numbering></numberingGroup><coverDate startDate="1971-08">August 1971</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="0044500" status="forIssue"><doi origin="wiley">10.1111/j.1440-1827.1971.tb00135.x</doi><idGroup><id type="unit" value="PIN445"></id></idGroup><countGroup><count type="pageTotal" number="14"></count></countGroup><titleGroup><title type="tocHeading1">Original Article</title></titleGroup><eventGroup><event type="firstOnline" date="2009-01-08"></event><event type="publishedOnlineFinalForm" date="2009-01-08"></event><event type="xmlConverted" agent="Converter:BPG_TO_WML3G version:2.3.2 mode:FullText source:HeaderRef result:HeaderRef" date="2010-03-02"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-02-06"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-11-03"></event></eventGroup><numberingGroup><numbering type="pageFirst" number="445">445</numbering><numbering type="pageLast" number="458">458</numbering></numberingGroup><linkGroup><link type="toTypesetVersion" href="file:PIN.PIN445.pdf"></link></linkGroup></publicationMeta><contentMeta><unparsedEditorialHistory>Received on Oct. 17, 1970</unparsedEditorialHistory><countGroup><count type="referenceTotal" number="19"></count><count type="linksCrossRef" number="3"></count></countGroup><titleGroup><title type="main">TWO MALE SIBLINGs' CASES OF SPECIFIC LIPIDOSIS FOUND BY ELECTRON MICROSCOPY</title></titleGroup><creators><creator creatorRole="author" xml:id="cr1" affiliationRef="#a1"><personName><givenNames>Kunitaro</givenNames><familyName>Yamaguchi</familyName></personName></creator><creator creatorRole="author" xml:id="cr2" affiliationRef="#a1"><personName><givenNames>Hideo</givenNames><familyName>Tsuchiyama</familyName></personName></creator><creator creatorRole="author" xml:id="cr3" affiliationRef="#a2"><personName><givenNames>Kimiko</givenNames><familyName>Tabata</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="a1"><unparsedAffiliation>*Department of Pathology, Faculty of Medicine, Nagasaki University, Nagasaki</unparsedAffiliation></affiliation><affiliation xml:id="a2"><unparsedAffiliation>**Department of Pediatrics, Omura Prefectural Hospital, Omura</unparsedAffiliation></affiliation></affiliationGroup><abstractGroup><abstract type="main" xml:lang="en"><p>Biopsy materials obtained from cervical lymph nodes and liver tissues of two male siblings, 5 years and 10 months old and 1 year and 11 months old, were studied electron microscopically. The results were summarized as follows: 1) Marked accumulation of lipid droplets, probably neutral fat, and cholesterol clefts in reticulum cells of lymph node, Kupffer cells and hepatic cells was the most prominent feature in these biopsies. 2) These lipids were found in both lysosomes and cytoplasmic matrices. Many of the lysosomes were considered to be autolysosomes or autophagosomes, because they contained fibrillar components, endoplasmic reticulum, glycogen particles and degraded organelles. It was suggested that these lipids might have been synthesized in lysosomes. 3) This disorder seems not to be included in the category of inborn lysosomal disease, and is considered as an unclassified one.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>TWO MALE SIBLINGs' CASES OF SPECIFIC LIPIDOSIS FOUND BY ELECTRON MICROSCOPY</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>TWO MALE SIBLINGs' CASES OF SPECIFIC LIPIDOSIS FOUND BY ELECTRON MICROSCOPY</title></titleInfo><name type="personal"><namePart type="given">Kunitaro</namePart><namePart type="family">Yamaguchi</namePart><affiliation>*Department of Pathology, Faculty of Medicine, Nagasaki University, Nagasaki</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Hideo</namePart><namePart type="family">Tsuchiyama</namePart><affiliation>*Department of Pathology, Faculty of Medicine, Nagasaki University, Nagasaki</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Kimiko</namePart><namePart type="family">Tabata</namePart><affiliation>**Department of Pediatrics, Omura Prefectural Hospital, Omura</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><place><placeTerm type="text">Oxford, UK</placeTerm></place><dateIssued encoding="w3cdtf">1971-08</dateIssued><edition>Received on Oct. 17, 1970</edition><copyrightDate encoding="w3cdtf">1971</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="references">19</extent></physicalDescription><abstract lang="en">Biopsy materials obtained from cervical lymph nodes and liver tissues of two male siblings, 5 years and 10 months old and 1 year and 11 months old, were studied electron microscopically. The results were summarized as follows: 1) Marked accumulation of lipid droplets, probably neutral fat, and cholesterol clefts in reticulum cells of lymph node, Kupffer cells and hepatic cells was the most prominent feature in these biopsies. 2) These lipids were found in both lysosomes and cytoplasmic matrices. Many of the lysosomes were considered to be autolysosomes or autophagosomes, because they contained fibrillar components, endoplasmic reticulum, glycogen particles and degraded organelles. It was suggested that these lipids might have been synthesized in lysosomes. 3) This disorder seems not to be included in the category of inborn lysosomal disease, and is considered as an unclassified one.</abstract><relatedItem type="host"><titleInfo><title>Pathology International</title></titleInfo><genre type="Journal">journal</genre><identifier type="ISSN">1320-5463</identifier><identifier type="eISSN">1440-1827</identifier><identifier type="DOI">10.1111/(ISSN)1440-1827</identifier><identifier type="PublisherID">PIN</identifier><part><date>1971</date><detail type="volume"><caption>vol.</caption><number>21</number></detail><detail type="issue"><caption>no.</caption><number>3</number></detail><extent unit="pages"><start>445</start><end>458</end><total>14</total></extent></part></relatedItem><identifier type="istex">08483FEE118B35885C12946CC4209F817DDEC0F2</identifier><identifier type="DOI">10.1111/j.1440-1827.1971.tb00135.x</identifier><identifier type="ArticleID">PIN445</identifier><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Blackwell Publishing Ltd</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Musique/explor/MagnificatV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000434 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 000434 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Musique
|area= MagnificatV1
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:08483FEE118B35885C12946CC4209F817DDEC0F2
|texte= TWO MALE SIBLINGs' CASES OF SPECIFIC LIPIDOSIS FOUND BY ELECTRON MICROSCOPY
}}
| This area was generated with Dilib version V0.6.31. |  |