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Clinical and laboratory findings with giant cell arteritis

Identifieur interne : 000238 ( Istex/Corpus ); précédent : 000237; suivant : 000239

Clinical and laboratory findings with giant cell arteritis

Auteurs : Peter Berlit

Source :

RBID : ISTEX:CD71AC51E4E3A2FC4491CE49C5F4A16C9ED1A1F4

Abstract

Out of 66 patients who were diagnosed as suffering from polymyalgia rheumatica (PMR; n = 40), temporal arteritis (AT;n = 14) or both (n = 12) in a 6.5 year period (incidence 3.4/100 000 per year), 9 died and 49 were followed up for an average period of 28 months. Exacerbations of the illness (n = 24) and complications in the course (n = 32) were more frequent with an initial ESR > 90 mm/h. Postural vertigo (n = 11), amaurosis fugax (n = 11) and polyneuropathy (n = 8) were the most frequent neurological complications. Persisting unilateral blindness and aromatic anosmia developed in 2 patients each. Complications were significantly more frequent in patients with initial symptoms of AT (χ2P < 0.001). CRP-levels correlated better with persisting symptoms in the course than did the ESR. Recurrences after treatment were significantly more frequent when the length of corticosteroid-therapy was less than 20 months (χ2P < 0.009). On follow up there were normal values for neopterin, tumour necrosis factor and antibodies against Borrelia burgdorferi.

Url:
DOI: 10.1016/0022-510X(92)90105-T

Links to Exploration step

ISTEX:CD71AC51E4E3A2FC4491CE49C5F4A16C9ED1A1F4

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