Glia cell stimulating factor (GSF): A new lymphokine
Identifieur interne : 000210 ( Istex/Corpus ); précédent : 000209; suivant : 000211Glia cell stimulating factor (GSF): A new lymphokine
Auteurs : A. Fontana ; R. Dubs ; R. Merchant ; S. Balsiger ; P. J. GrobSource :
- Journal of Neuroimmunology [ 0165-5728 ] ; 1981.
Abstract
The effect of activated-lymphocyte supernatant on glia cells was investigated. When treated in vitro with Concanavalin A (ConA), murine spleen cells released a soluble product, termed glia cell stimulating factor (GSF), which stimulated RNA and DNA synthesis in cultured murine glia cells. Furthermore, GSF appeared to promote the maturation of undifferentiated glia cells to astrocytes having a high content of glial fibrillary acidic protein. GSF secretion occurred after a lag period of 16 hours and proceeded at a constant rate for more than 48 hours. This GSF produced by ConA-stimulated murine lymphocytes has an apparent molecular weight between 60,000 and 80,000. Antigenic stimulation of primed lymph node cells with BGG resulted in a similar GSF production. Cellular sources of mitogen-induced GSF were investigated by using isolated lymphoid populations. GSF release by ConA-activated pure T-lymphocytes reconstituted with peritoneal macrophages was equivalent to that of unseparated spleen cells, whereas GSF production by T-lymphocytes alone was low. Macrophages alone did not elaborate detectable levels of GSF. GSF was also secreted by enriched B-lymphocytes populations stimulated by Protein A. Formation of GSF was suppressed when cytochalasin B or cyclo
Url:
DOI: 10.1016/0165-5728(82)90075-3
Links to Exploration step
ISTEX:C7079CBF195318007D30B01A3BCF325570C21E5ALe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Glia cell stimulating factor (GSF): A new lymphokine</title><author><name sortKey="Fontana, A" sort="Fontana, A" uniqKey="Fontana A" first="A." last="Fontana">A. Fontana</name><affiliation><mods:affiliation>Department of Internal Medicine, Section of Clinical Immunology, Switzerland</mods:affiliation></affiliation></author><author><name sortKey="Dubs, R" sort="Dubs, R" uniqKey="Dubs R" first="R." last="Dubs">R. Dubs</name><affiliation><mods:affiliation>Department of Internal Medicine, Section of Clinical Immunology, Switzerland</mods:affiliation></affiliation></author><author><name sortKey="Merchant, R" sort="Merchant, R" uniqKey="Merchant R" first="R." last="Merchant">R. Merchant</name><affiliation><mods:affiliation>Section of Experimental Oncology, University Hospital, Zürich, Switzerland</mods:affiliation></affiliation></author><author><name sortKey="Balsiger, S" sort="Balsiger, S" uniqKey="Balsiger S" first="S." last="Balsiger">S. Balsiger</name><affiliation><mods:affiliation>Department of Internal Medicine, Section of Clinical Immunology, Switzerland</mods:affiliation></affiliation></author><author><name sortKey="Grob, P J" sort="Grob, P J" uniqKey="Grob P" first="P. J." last="Grob">P. J. Grob</name><affiliation><mods:affiliation>Department of Internal Medicine, Section of Clinical Immunology, Switzerland</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:C7079CBF195318007D30B01A3BCF325570C21E5A</idno><date when="1982" year="1982">1982</date><idno type="doi">10.1016/0165-5728(82)90075-3</idno><idno type="url">https://api.istex.fr/document/C7079CBF195318007D30B01A3BCF325570C21E5A/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000210</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000210</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a">Glia cell stimulating factor (GSF): A new lymphokine</title><author><name sortKey="Fontana, A" sort="Fontana, A" uniqKey="Fontana A" first="A." last="Fontana">A. Fontana</name><affiliation><mods:affiliation>Department of Internal Medicine, Section of Clinical Immunology, Switzerland</mods:affiliation></affiliation></author><author><name sortKey="Dubs, R" sort="Dubs, R" uniqKey="Dubs R" first="R." last="Dubs">R. Dubs</name><affiliation><mods:affiliation>Department of Internal Medicine, Section of Clinical Immunology, Switzerland</mods:affiliation></affiliation></author><author><name sortKey="Merchant, R" sort="Merchant, R" uniqKey="Merchant R" first="R." last="Merchant">R. Merchant</name><affiliation><mods:affiliation>Section of Experimental Oncology, University Hospital, Zürich, Switzerland</mods:affiliation></affiliation></author><author><name sortKey="Balsiger, S" sort="Balsiger, S" uniqKey="Balsiger S" first="S." last="Balsiger">S. Balsiger</name><affiliation><mods:affiliation>Department of Internal Medicine, Section of Clinical Immunology, Switzerland</mods:affiliation></affiliation></author><author><name sortKey="Grob, P J" sort="Grob, P J" uniqKey="Grob P" first="P. J." last="Grob">P. J. Grob</name><affiliation><mods:affiliation>Department of Internal Medicine, Section of Clinical Immunology, Switzerland</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Neuroimmunology</title><title level="j" type="abbrev">JNI</title><idno type="ISSN">0165-5728</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1981">1981</date><biblScope unit="volume">2</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="55">55</biblScope><biblScope unit="page" to="71">71</biblScope></imprint><idno type="ISSN">0165-5728</idno></series><idno type="istex">C7079CBF195318007D30B01A3BCF325570C21E5A</idno><idno type="DOI">10.1016/0165-5728(82)90075-3</idno><idno type="PII">0165-5728(82)90075-3</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0165-5728</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The effect of activated-lymphocyte supernatant on glia cells was investigated. When treated in vitro with Concanavalin A (ConA), murine spleen cells released a soluble product, termed glia cell stimulating factor (GSF), which stimulated RNA and DNA synthesis in cultured murine glia cells. Furthermore, GSF appeared to promote the maturation of undifferentiated glia cells to astrocytes having a high content of glial fibrillary acidic protein. GSF secretion occurred after a lag period of 16 hours and proceeded at a constant rate for more than 48 hours. This GSF produced by ConA-stimulated murine lymphocytes has an apparent molecular weight between 60,000 and 80,000. Antigenic stimulation of primed lymph node cells with BGG resulted in a similar GSF production. Cellular sources of mitogen-induced GSF were investigated by using isolated lymphoid populations. GSF release by ConA-activated pure T-lymphocytes reconstituted with peritoneal macrophages was equivalent to that of unseparated spleen cells, whereas GSF production by T-lymphocytes alone was low. Macrophages alone did not elaborate detectable levels of GSF. GSF was also secreted by enriched B-lymphocytes populations stimulated by Protein A. Formation of GSF was suppressed when cytochalasin B or cyclo</div></front></TEI><istex><corpusName>elsevier</corpusName><author><json:item><name>A. Fontana</name><affiliations><json:string>Department of Internal Medicine, Section of Clinical Immunology, Switzerland</json:string></affiliations></json:item><json:item><name>R. Dubs</name><affiliations><json:string>Department of Internal Medicine, Section of Clinical Immunology, Switzerland</json:string></affiliations></json:item><json:item><name>R. Merchant</name><affiliations><json:string>Section of Experimental Oncology, University Hospital, Zürich, Switzerland</json:string></affiliations></json:item><json:item><name>S. Balsiger</name><affiliations><json:string>Department of Internal Medicine, Section of Clinical Immunology, Switzerland</json:string></affiliations></json:item><json:item><name>P.J. Grob</name><affiliations><json:string>Department of Internal Medicine, Section of Clinical Immunology, Switzerland</json:string></affiliations></json:item></author><language><json:string>eng</json:string></language><abstract>The effect of activated-lymphocyte supernatant on glia cells was investigated. When treated in vitro with Concanavalin A (ConA), murine spleen cells released a soluble product, termed glia cell stimulating factor (GSF), which stimulated RNA and DNA synthesis in cultured murine glia cells. Furthermore, GSF appeared to promote the maturation of undifferentiated glia cells to astrocytes having a high content of glial fibrillary acidic protein. GSF secretion occurred after a lag period of 16 hours and proceeded at a constant rate for more than 48 hours. This GSF produced by ConA-stimulated murine lymphocytes has an apparent molecular weight between 60,000 and 80,000. Antigenic stimulation of primed lymph node cells with BGG resulted in a similar GSF production. Cellular sources of mitogen-induced GSF were investigated by using isolated lymphoid populations. GSF release by ConA-activated pure T-lymphocytes reconstituted with peritoneal macrophages was equivalent to that of unseparated spleen cells, whereas GSF production by T-lymphocytes alone was low. Macrophages alone did not elaborate detectable levels of GSF. GSF was also secreted by enriched B-lymphocytes populations stimulated by Protein A. Formation of GSF was suppressed when cytochalasin B or cyclo</abstract><qualityIndicators><score>7.22</score><pdfVersion>1.3</pdfVersion><pdfPageSize>432 x 648 pts</pdfPageSize><refBibsNative>true</refBibsNative><keywordCount>0</keywordCount><abstractCharCount>1271</abstractCharCount><pdfWordCount>10258</pdfWordCount><pdfCharCount>29452</pdfCharCount><pdfPageCount>17</pdfPageCount><abstractWordCount>185</abstractWordCount></qualityIndicators><title>Glia cell stimulating factor (GSF): A new lymphokine</title><pii><json:string>0165-5728(82)90075-3</json:string></pii><genre><json:string>research-article</json:string></genre><serie><volume>56</volume><pages><last>77</last><first>72</first></pages><genre></genre><language><json:string>unknown</json:string></language><title>Proc. Nat. Acad. Sci. (USA)</title></serie><host><volume>2</volume><pii><json:string>S0165-5728(00)X0242-1</json:string></pii><pages><last>71</last><first>55</first></pages><issn><json:string>0165-5728</json:string></issn><issue>1</issue><genre><json:string>Journal</json:string></genre><language><json:string>unknown</json:string></language><title>Journal of Neuroimmunology</title><publicationDate>1982</publicationDate></host><categories><wos><json:string>IMMUNOLOGY</json:string><json:string>NEUROSCIENCES</json:string></wos></categories><publicationDate>1981</publicationDate><copyrightDate>1982</copyrightDate><doi><json:string>10.1016/0165-5728(82)90075-3</json:string></doi><id>C7079CBF195318007D30B01A3BCF325570C21E5A</id><fulltext><json:item><original>true</original><mimetype>application/pdf</mimetype><extension>pdf</extension><uri>https://api.istex.fr/document/C7079CBF195318007D30B01A3BCF325570C21E5A/fulltext/pdf</uri></json:item><json:item><original>true</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/C7079CBF195318007D30B01A3BCF325570C21E5A/fulltext/txt</uri></json:item><json:item><original>false</original><mimetype>application/zip</mimetype><extension>zip</extension><uri>https://api.istex.fr/document/C7079CBF195318007D30B01A3BCF325570C21E5A/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/C7079CBF195318007D30B01A3BCF325570C21E5A/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a">Glia cell stimulating factor (GSF): A new lymphokine</title><title level="a" type="sub" xml:lang="">Part 1. Cellular sources and partial purification of murine GSF, role of cytoskeleton and protein synthesis in its production</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>ELSEVIER</publisher><availability><p>ELSEVIER</p></availability><date>1982</date></publicationStmt><notesStmt><note>This work was supported by a grant from the Sandoz Foundation and the Swiss National Science Foundation (Project No. 3.077-0.76).</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a">Glia cell stimulating factor (GSF): A new lymphokine</title><title level="a" type="sub">Part 1. Cellular sources and partial purification of murine GSF, role of cytoskeleton and protein synthesis in its production</title><author><persName><forename type="first">A.</forename><surname>Fontana</surname></persName><note type="biography">Reprint requests should be sent to: Adriano Fontana, M.D., Section of Clinical Immunology, University Hospital, Haldeliweg 4, 8044 Zürich, Switzerland.</note><affiliation>Reprint requests should be sent to: Adriano Fontana, M.D., Section of Clinical Immunology, University Hospital, Haldeliweg 4, 8044 Zürich, Switzerland.</affiliation><affiliation>Department of Internal Medicine, Section of Clinical Immunology, Switzerland</affiliation></author><author><persName><forename type="first">R.</forename><surname>Dubs</surname></persName><affiliation>Department of Internal Medicine, Section of Clinical Immunology, Switzerland</affiliation></author><author><persName><forename type="first">R.</forename><surname>Merchant</surname></persName><affiliation>Section of Experimental Oncology, University Hospital, Zürich, Switzerland</affiliation></author><author><persName><forename type="first">S.</forename><surname>Balsiger</surname></persName><affiliation>Department of Internal Medicine, Section of Clinical Immunology, Switzerland</affiliation></author><author><persName><forename type="first">P.J.</forename><surname>Grob</surname></persName><affiliation>Department of Internal Medicine, Section of Clinical Immunology, Switzerland</affiliation></author></analytic><monogr><title level="j">Journal of Neuroimmunology</title><title level="j" type="abbrev">JNI</title><idno type="pISSN">0165-5728</idno><idno type="PII">S0165-5728(00)X0242-1</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1981"></date><biblScope unit="volume">2</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="55">55</biblScope><biblScope unit="page" to="71">71</biblScope></imprint></monogr><idno type="istex">C7079CBF195318007D30B01A3BCF325570C21E5A</idno><idno type="DOI">10.1016/0165-5728(82)90075-3</idno><idno type="PII">0165-5728(82)90075-3</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>1982</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>The effect of activated-lymphocyte supernatant on glia cells was investigated. When treated in vitro with Concanavalin A (ConA), murine spleen cells released a soluble product, termed glia cell stimulating factor (GSF), which stimulated RNA and DNA synthesis in cultured murine glia cells. Furthermore, GSF appeared to promote the maturation of undifferentiated glia cells to astrocytes having a high content of glial fibrillary acidic protein. GSF secretion occurred after a lag period of 16 hours and proceeded at a constant rate for more than 48 hours. This GSF produced by ConA-stimulated murine lymphocytes has an apparent molecular weight between 60,000 and 80,000. Antigenic stimulation of primed lymph node cells with BGG resulted in a similar GSF production. Cellular sources of mitogen-induced GSF were investigated by using isolated lymphoid populations. GSF release by ConA-activated pure T-lymphocytes reconstituted with peritoneal macrophages was equivalent to that of unseparated spleen cells, whereas GSF production by T-lymphocytes alone was low. Macrophages alone did not elaborate detectable levels of GSF. GSF was also secreted by enriched B-lymphocytes populations stimulated by Protein A. Formation of GSF was suppressed when cytochalasin B or cyclo</p></abstract></profileDesc><revisionDesc><change when="1981-07-21">Registration</change><change when="1981">Published</change></revisionDesc></teiHeader></istex:fulltextTEI></fulltext><metadata><istex:metadataXml wicri:clean="Elsevier, elements deleted: tail"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" </istex:xmlDeclaration><istex:docType PUBLIC="-//ES//DTD journal article DTD version 4.5.2//EN//XML" URI="art452.dtd" name="istex:docType"></istex:docType><istex:document><converted-article version="4.5.2" docsubtype="fla"><item-info><jid>JNI</jid><aid>90075</aid><ce:pii>0165-5728(82)90075-3</ce:pii><ce:doi>10.1016/0165-5728(82)90075-3</ce:doi><ce:copyright type="unknown" year="1982"></ce:copyright></item-info><head><ce:article-footnote><ce:label>☆</ce:label><ce:note-para>This work was supported by a grant from the Sandoz Foundation and the Swiss National Science Foundation (Project No. 3.077-0.76).</ce:note-para></ce:article-footnote><ce:title>Glia cell stimulating factor (GSF): A new lymphokine</ce:title><ce:subtitle>Part 1. Cellular sources and partial purification of murine GSF, role of cytoskeleton and protein synthesis in its production</ce:subtitle><ce:author-group><ce:author><ce:given-name>A.</ce:given-name><ce:surname>Fontana</ce:surname><ce:cross-ref refid="COR1"><ce:sup>∗</ce:sup></ce:cross-ref><ce:cross-ref refid="AFF1"><ce:sup>1</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>R.</ce:given-name><ce:surname>Dubs</ce:surname><ce:cross-ref refid="AFF1"><ce:sup>1</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>R.</ce:given-name><ce:surname>Merchant</ce:surname><ce:cross-ref refid="AFF2"><ce:sup>2</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>S.</ce:given-name><ce:surname>Balsiger</ce:surname><ce:cross-ref refid="AFF1"><ce:sup>1</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>P.J.</ce:given-name><ce:surname>Grob</ce:surname><ce:cross-ref refid="AFF1"><ce:sup>1</ce:sup></ce:cross-ref></ce:author><ce:affiliation id="AFF1"><ce:label>a</ce:label><ce:textfn>Department of Internal Medicine, Section of Clinical Immunology, Switzerland</ce:textfn></ce:affiliation><ce:affiliation id="AFF2"><ce:label>b</ce:label><ce:textfn>Section of Experimental Oncology, University Hospital, Zürich, Switzerland</ce:textfn></ce:affiliation><ce:correspondence id="COR1"><ce:label>∗</ce:label><ce:text>Reprint requests should be sent to: Adriano Fontana, M.D., Section of Clinical Immunology, University Hospital, Haldeliweg 4, 8044 Zürich, Switzerland.</ce:text></ce:correspondence></ce:author-group><ce:date-received day="11" month="5" year="1981"></ce:date-received><ce:date-accepted day="21" month="7" year="1981"></ce:date-accepted><ce:abstract><ce:section-title>Abstract</ce:section-title><ce:abstract-sec><ce:simple-para id="SP0005">The effect of activated-lymphocyte supernatant on glia cells was investigated. When treated in vitro with Concanavalin A (ConA), murine spleen cells released a soluble product, termed glia cell stimulating factor (GSF), which stimulated RNA and DNA synthesis in cultured murine glia cells. Furthermore, GSF appeared to promote the maturation of undifferentiated glia cells to astrocytes having a high content of glial fibrillary acidic protein. GSF secretion occurred after a lag period of 16 hours and proceeded at a constant rate for more than 48 hours. This GSF produced by ConA-stimulated murine lymphocytes has an apparent molecular weight between 60,000 and 80,000. Antigenic stimulation of primed lymph node cells with BGG resulted in a similar GSF production. Cellular sources of mitogen-induced GSF were investigated by using isolated lymphoid populations. GSF release by ConA-activated pure T-lymphocytes reconstituted with peritoneal macrophages was equivalent to that of unseparated spleen cells, whereas GSF production by T-lymphocytes alone was low. Macrophages alone did not elaborate detectable levels of GSF. GSF was also secreted by enriched B-lymphocytes populations stimulated by Protein A. Formation of GSF was suppressed when cytochalasin B or cyclo</ce:simple-para></ce:abstract-sec></ce:abstract></head></converted-article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo><title>Glia cell stimulating factor (GSF): A new lymphokine</title><subTitle>Part 1. Cellular sources and partial purification of murine GSF, role of cytoskeleton and protein synthesis in its production</subTitle></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Glia cell stimulating factor (GSF): A new lymphokine</title><subTitle>Part 1. Cellular sources and partial purification of murine GSF, role of cytoskeleton and protein synthesis in its production</subTitle></titleInfo><name type="personal"><namePart type="given">A.</namePart><namePart type="family">Fontana</namePart><affiliation>Department of Internal Medicine, Section of Clinical Immunology, Switzerland</affiliation><description>Reprint requests should be sent to: Adriano Fontana, M.D., Section of Clinical Immunology, University Hospital, Haldeliweg 4, 8044 Zürich, Switzerland.</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R.</namePart><namePart type="family">Dubs</namePart><affiliation>Department of Internal Medicine, Section of Clinical Immunology, Switzerland</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R.</namePart><namePart type="family">Merchant</namePart><affiliation>Section of Experimental Oncology, University Hospital, Zürich, Switzerland</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S.</namePart><namePart type="family">Balsiger</namePart><affiliation>Department of Internal Medicine, Section of Clinical Immunology, Switzerland</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P.J.</namePart><namePart type="family">Grob</namePart><affiliation>Department of Internal Medicine, Section of Clinical Immunology, Switzerland</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="Full-length article"></genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">1981</dateIssued><dateValid encoding="w3cdtf">1981-07-21</dateValid><copyrightDate encoding="w3cdtf">1982</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="en">The effect of activated-lymphocyte supernatant on glia cells was investigated. When treated in vitro with Concanavalin A (ConA), murine spleen cells released a soluble product, termed glia cell stimulating factor (GSF), which stimulated RNA and DNA synthesis in cultured murine glia cells. Furthermore, GSF appeared to promote the maturation of undifferentiated glia cells to astrocytes having a high content of glial fibrillary acidic protein. GSF secretion occurred after a lag period of 16 hours and proceeded at a constant rate for more than 48 hours. This GSF produced by ConA-stimulated murine lymphocytes has an apparent molecular weight between 60,000 and 80,000. Antigenic stimulation of primed lymph node cells with BGG resulted in a similar GSF production. Cellular sources of mitogen-induced GSF were investigated by using isolated lymphoid populations. GSF release by ConA-activated pure T-lymphocytes reconstituted with peritoneal macrophages was equivalent to that of unseparated spleen cells, whereas GSF production by T-lymphocytes alone was low. Macrophages alone did not elaborate detectable levels of GSF. GSF was also secreted by enriched B-lymphocytes populations stimulated by Protein A. Formation of GSF was suppressed when cytochalasin B or cyclo</abstract><note>This work was supported by a grant from the Sandoz Foundation and the Swiss National Science Foundation (Project No. 3.077-0.76).</note><relatedItem type="host"><titleInfo><title>Journal of Neuroimmunology</title></titleInfo><titleInfo type="abbreviated"><title>JNI</title></titleInfo><genre type="Journal">journal</genre><originInfo><dateIssued encoding="w3cdtf">198201</dateIssued></originInfo><identifier type="ISSN">0165-5728</identifier><identifier type="PII">S0165-5728(00)X0242-1</identifier><part><date>198201</date><detail type="volume"><number>2</number><caption>vol.</caption></detail><detail type="issue"><number>1</number><caption>no.</caption></detail><extent unit="issue pages"><start>1</start><end>92</end></extent><extent unit="pages"><start>55</start><end>71</end></extent></part></relatedItem><identifier type="istex">C7079CBF195318007D30B01A3BCF325570C21E5A</identifier><identifier type="DOI">10.1016/0165-5728(82)90075-3</identifier><identifier type="PII">0165-5728(82)90075-3</identifier><recordInfo><recordContentSource>ELSEVIER</recordContentSource></recordInfo></mods></metadata></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Musique/explor/MagnificatV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000210 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 000210 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Musique
|area= MagnificatV1
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:C7079CBF195318007D30B01A3BCF325570C21E5A
|texte= Glia cell stimulating factor (GSF): A new lymphokine
}}
| This area was generated with Dilib version V0.6.31. |  |